FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8796, 333 aa 1>>>pF1KB8796 333 - 333 aa - 333 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2646+/-0.000944; mu= 16.1868+/- 0.056 mean_var=124.8461+/-38.845, 0's: 0 Z-trim(106.1): 268 B-trim: 1125 in 2/47 Lambda= 0.114785 statistics sampled from 8301 (8776) to 8301 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.27), width: 16 Scan time: 2.590 The best scores are: opt bits E(32554) CCDS2736.1 XCR1 gene_id:2829|Hs108|chr3 ( 333) 2242 383.0 1.8e-106 CCDS43078.1 CCR2 gene_id:729230|Hs108|chr3 ( 374) 699 127.6 1.6e-29 CCDS46813.1 CCR2 gene_id:729230|Hs108|chr3 ( 360) 696 127.0 2.2e-29 CCDS43069.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 355) 689 125.9 4.9e-29 CCDS54571.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 387) 689 125.9 5.2e-29 CCDS46420.1 CXCR4 gene_id:7852|Hs108|chr2 ( 352) 608 112.5 5.4e-25 CCDS33295.1 CXCR4 gene_id:7852|Hs108|chr2 ( 356) 608 112.5 5.4e-25 CCDS2735.1 CXCR6 gene_id:10663|Hs108|chr3 ( 342) 542 101.5 1e-21 CCDS3075.1 ACKR4 gene_id:51554|Hs108|chr3 ( 350) 487 92.4 5.7e-19 CCDS2684.1 CCR8 gene_id:1237|Hs108|chr3 ( 355) 443 85.1 9.1e-17 CCDS14416.1 CXCR3 gene_id:2833|Hs108|chrX ( 368) 415 80.5 2.3e-15 CCDS48135.1 CXCR3 gene_id:2833|Hs108|chrX ( 415) 415 80.6 2.5e-15 CCDS2656.1 CCR4 gene_id:1233|Hs108|chr3 ( 360) 410 79.7 4e-15 CCDS2148.1 GPR17 gene_id:2840|Hs108|chr2 ( 367) 400 78.0 1.3e-14 CCDS2706.1 ACKR2 gene_id:1238|Hs108|chr3 ( 384) 386 75.7 6.6e-14 CCDS2739.1 CCR5 gene_id:1234|Hs108|chr3 ( 352) 372 73.4 3.1e-13 CCDS2408.1 CXCR2 gene_id:3579|Hs108|chr2 ( 360) 366 72.4 6.3e-13 CCDS43079.1 CCRL2 gene_id:9034|Hs108|chr3 ( 344) 358 71.0 1.5e-12 CCDS46814.1 CCRL2 gene_id:9034|Hs108|chr3 ( 356) 358 71.1 1.6e-12 CCDS10429.1 SSTR5 gene_id:6755|Hs108|chr16 ( 364) 350 69.7 4e-12 CCDS2738.1 CCR3 gene_id:1232|Hs108|chr3 ( 355) 346 69.1 6.2e-12 CCDS54574.1 CCR3 gene_id:1232|Hs108|chr3 ( 376) 346 69.1 6.4e-12 CCDS5298.1 CCR6 gene_id:1235|Hs108|chr6 ( 374) 339 67.9 1.4e-11 CCDS2737.1 CCR1 gene_id:1230|Hs108|chr3 ( 355) 334 67.1 2.5e-11 CCDS9412.1 CYSLTR2 gene_id:57105|Hs108|chr13 ( 346) 332 66.7 3e-11 CCDS2409.1 CXCR1 gene_id:3577|Hs108|chr2 ( 350) 329 66.2 4.3e-11 CCDS5322.1 GPER1 gene_id:2852|Hs108|chr7 ( 375) 328 66.1 5.1e-11 CCDS12049.1 KISS1R gene_id:84634|Hs108|chr19 ( 398) 325 65.7 7.4e-11 >>CCDS2736.1 XCR1 gene_id:2829|Hs108|chr3 (333 aa) initn: 2242 init1: 2242 opt: 2242 Z-score: 2024.9 bits: 383.0 E(32554): 1.8e-106 Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB8 MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVKYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVKYE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 SLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDYSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 TIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDYSEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 TWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 YNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVKFRTHLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 YNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVKFRTHLKH 250 260 270 280 290 300 310 320 330 pF1KB8 VLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY ::::::::::::::::::::::::::::::::: CCDS27 VLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY 310 320 330 >>CCDS43078.1 CCR2 gene_id:729230|Hs108|chr3 (374 aa) initn: 655 init1: 356 opt: 699 Z-score: 643.4 bits: 127.6 E(32554): 1.6e-29 Smith-Waterman score: 699; 36.5% identity (68.4% similar) in 329 aa overlap (4-323:16-336) 10 20 30 40 pF1KB8 MESSGNPESTTFFYYDLQSQPCE--NQAWVFATLATTVLYCLVFLLSL ::. : :::: :: . ::. . . : : :: :::.... CCDS43 MLSTSRSRFIRNTNESGE-EVTTFFDYDY-GAPCHKFDVKQIGAQLLPP-LYSLVFIFGF 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 VGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLN ::: ::. .:.. ..:. ::.:..::: .:::.: ::.: ::.:. .:::.. CCDS43 VGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFT 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 MIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTI .. :. ...:::. ..:: :::..: . .:.. :. :.... .:......:. : CCDS43 GLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGII 120 130 140 150 160 170 170 180 190 200 210 pF1KB8 FHKVLSSG----CD-YSELTWY-LTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRS-KR : : . : : : . ..... : ..: : :...:: ::.::.: :. :. CCDS43 FTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKK 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 RHRTVKLIFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSH :::.:..::.:...::: : :::....:.:. . . .::. .::. : . ..:...: CCDS43 RHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTH 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 CCFNPVLYVFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY ::.::..:.::: :::. : :. ::. :: . .:: CCDS43 CCINPIIYAFVGEKFRS-LFHIALG---CRI-APLQKPVCGGPGVRPGKNVKVTTQGLLD 300 310 320 330 340 350 CCDS43 GRGKGKSIGRAPEASLQDKEGA 360 370 >>CCDS46813.1 CCR2 gene_id:729230|Hs108|chr3 (360 aa) initn: 659 init1: 356 opt: 696 Z-score: 640.9 bits: 127.0 E(32554): 2.2e-29 Smith-Waterman score: 705; 36.7% identity (69.1% similar) in 324 aa overlap (4-313:16-333) 10 20 30 40 pF1KB8 MESSGNPESTTFFYYDLQSQPCE--NQAWVFATLATTVLYCLVFLLSL ::. : :::: :: . ::. . . : : :: :::.... CCDS46 MLSTSRSRFIRNTNESGE-EVTTFFDYDYGA-PCHKFDVKQIGAQLLPP-LYSLVFIFGF 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 VGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLN ::: ::. .:.. ..:. ::.:..::: .:::.: ::.: ::.:. .:::.. CCDS46 VGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFT 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 MIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTI .. :. ...:::. ..:: :::..: . .:.. :. :.... .:......:. : CCDS46 GLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGII 120 130 140 150 160 170 170 180 190 200 210 pF1KB8 FHKVLSSG----CD-YSELTWY-LTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRS-KR : : . : : : . ..... : ..: : :...:: ::.::.: :. :. CCDS46 FTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKK 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 RHRTVKLIFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSH :::.:..::.:...::: : :::....:.:. . . .::. .::. : . ..:...: CCDS46 RHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTH 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 CCFNPVLYVFVGVKFRTHL-----KHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY ::.::..:.::: ::: .: ::. ..: :. : : CCDS46 CCINPIIYAFVGEKFRRYLSVFFRKHITKRF--CK-QCPVFYRETVDGVTSTNTPSTGEQ 300 310 320 330 340 350 CCDS46 EVSAGL 360 >>CCDS43069.1 CX3CR1 gene_id:1524|Hs108|chr3 (355 aa) initn: 653 init1: 349 opt: 689 Z-score: 634.7 bits: 125.9 E(32554): 4.9e-29 Smith-Waterman score: 689; 37.0% identity (70.0% similar) in 303 aa overlap (7-301:5-307) 10 20 30 40 50 pF1KB8 MESSGNPESTTF-FYYDLQSQPCE-NQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVK :::.: : :: .. : .. ::.:. ...: ..: ..:::: ::...:.. CCDS43 MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSVIFAIGLVGNLLVVFALTN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 YESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIF .. .:.:.:..::: ::::.:. :: : : . .::. . .: :....::: CCDS43 SKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNAMCKFTTAFFFIGFFGSIF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGC--D :.:...: :::..: ... :.. : ....::.:.:: . . .: : . : : CCDS43 FITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVAAPQFMFTKQKENECLGD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 YSELT---W-YLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVV : :. : : .: . : ::: : :. .:: .:..::: ..... ...:::. .:. CCDS43 YPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGV ..:: : ::: .::.:: ... ::. ...:. :: . ...::::::.::..:.:.: CCDS43 VFFLFWTPYNVMIFLETLKLYDFFPSCDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGE 240 250 260 270 280 290 300 310 320 330 pF1KB8 KFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY ::: .: :. CCDS43 KFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL 300 310 320 330 340 350 >>CCDS54571.1 CX3CR1 gene_id:1524|Hs108|chr3 (387 aa) initn: 653 init1: 349 opt: 689 Z-score: 634.3 bits: 125.9 E(32554): 5.2e-29 Smith-Waterman score: 689; 37.0% identity (70.0% similar) in 303 aa overlap (7-301:37-339) 10 20 30 pF1KB8 MESSGNPESTTF-FYYDLQSQPCE-NQAWVFATLAT :::.: : :: .. : .. ::.:. CCDS54 AFKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFGTVFL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 TVLYCLVFLLSLVGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWG ...: ..: ..:::: ::...:.. .. .:.:.:..::: ::::.:. :: : CCDS54 SIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 WVLGDFLCKLLNMIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVW : . .::. . .: :....::::.:...: :::..: ... :.. : ....:: CCDS54 KGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVW 130 140 150 160 170 180 160 170 180 190 200 pF1KB8 VASILSSILDTIFHKVLSSGC--DYSELT---W-YLTSVYQHNLFFLLSLGIILFCYVEI .:.:: . . .: : . : :: :. : : .: . : ::: : :. .:: .: CCDS54 AAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRI 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 LRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYA ..::: ..... ...:::. .:...:: : ::: .::.:: ... ::. ...:. : CCDS54 IQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKDLRLA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 LLICRNLAFSHCCFNPVLYVFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYE : . ...::::::.::..:.:.: ::: .: :. CCDS54 LSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRH 310 320 330 340 350 360 330 pF1KB8 GASFY CCDS54 GSVLSSNFTYHTSDGDALLLL 370 380 >>CCDS46420.1 CXCR4 gene_id:7852|Hs108|chr2 (352 aa) initn: 579 init1: 321 opt: 608 Z-score: 562.3 bits: 112.5 E(32554): 5.4e-25 Smith-Waterman score: 608; 31.6% identity (67.7% similar) in 297 aa overlap (15-302:21-317) 10 20 30 40 50 pF1KB8 MESSGNPESTTFFYYDLQSQPC-ENQAWVFATLATTVLYCLVFLLSLVGNSLVL :: ...:: ... : . ..: ..:: ..:::.::. CCDS46 MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 WVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISL :. ..:.:.:. . :.: ..::.:. :: : .: .:.:::: ...:....: CCDS46 LVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 YSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSS :::...:..... :::..: .. : : . .: ..::. ..: .: : :: .: . CCDS46 YSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEA 130 140 150 160 170 180 180 190 200 210 220 pF1KB8 G----CD--YSELTWYLTSVYQHNLFFLLSLGIILF-CYVEILRTLFRSRSKRRHRTVKL :: : . : .. .:: . :. ::... :: :. : .:.........: CCDS46 DDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKT 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 IFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRS-CEAKQQLEYALLICRNLAFSHCCFNPV ...:.: : :: . . ..... .::.. :: .. .. . : . ::: :::.::. CCDS46 TVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPI 250 260 270 280 290 300 290 300 310 320 330 pF1KB8 LYVFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY ::.:.:.::.: .:.: CCDS46 LYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS 310 320 330 340 350 >>CCDS33295.1 CXCR4 gene_id:7852|Hs108|chr2 (356 aa) initn: 579 init1: 321 opt: 608 Z-score: 562.2 bits: 112.5 E(32554): 5.4e-25 Smith-Waterman score: 608; 31.6% identity (67.7% similar) in 297 aa overlap (15-302:25-321) 10 20 30 40 pF1KB8 MESSGNPESTTFFYYDLQSQPC-ENQAWVFATLATTVLYCLVFLLSLVGN :: ...:: ... : . ..: ..:: ..::: CCDS33 MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 SLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIF .::. :. ..:.:.:. . :.: ..::.:. :: : .: .:.:::: ...:. CCDS33 GLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 SISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHK ...::::...:..... :::..: .. : : . .: ..::. ..: .: : :: . CCDS33 TVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFAN 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 VLSSG----CD--YSELTWYLTSVYQHNLFFLLSLGIILF-CYVEILRTLFRSRSKRRHR : . :: : . : .. .:: . :. ::... :: :. : .:....... CCDS33 VSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 TVKLIFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRS-CEAKQQLEYALLICRNLAFSHCC ..: ...:.: : :: . . ..... .::.. :: .. .. . : . ::: ::: CCDS33 ALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCC 250 260 270 280 290 300 290 300 310 320 330 pF1KB8 FNPVLYVFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY .::.::.:.:.::.: .:.: CCDS33 LNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS 310 320 330 340 350 >>CCDS2735.1 CXCR6 gene_id:10663|Hs108|chr3 (342 aa) initn: 464 init1: 301 opt: 542 Z-score: 503.3 bits: 101.5 E(32554): 1e-21 Smith-Waterman score: 542; 31.4% identity (66.7% similar) in 303 aa overlap (8-303:8-304) 10 20 30 40 50 pF1KB8 MESSGNPESTTFFYYDLQSQPCENQAWV-FATLATTVLYCLVFLLSLVGNSLVLWVLVKY :. : .. .:: :.: .. :. . .: .::. .:::::::: . . : CCDS27 MAEHDYHEDYGFSSFNDSSQE-EHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFY 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 ESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFF ..:.:::..:..:: :.::::.: :: : ::.:. .:: : :..:..:.:... CCDS27 HKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 LTIMTIHRYLSVVSPLSTLRVPTLRCRV--LVTMAVWVASILSSILDTIFHKVLSSG--- :: .:. :.. ::. .. . : .... .:: :.: :. . :. .:.. CCDS27 LTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 CDY-SELTWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVA : : .: .. . : .: :.: : .. :: :..::... . ..::..:.:: .... CCDS27 CGYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 YFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVK ..:. :.:. :... : ...:.... . .:. . :.:::::.::..: CCDS27 FLLTQMPFNLMKFIRSTHWEYY-----AMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLK 240 250 260 270 280 290 300 310 320 330 pF1KB8 FRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY :: .. .... CCDS27 FRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL 300 310 320 330 340 >>CCDS3075.1 ACKR4 gene_id:51554|Hs108|chr3 (350 aa) initn: 496 init1: 249 opt: 487 Z-score: 454.0 bits: 92.4 E(32554): 5.7e-19 Smith-Waterman score: 487; 28.5% identity (65.6% similar) in 302 aa overlap (29-319:39-335) 10 20 30 40 50 pF1KB8 MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVK :: . :. .::...:.:::.:. . . CCDS30 TDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNSMVVAIYAY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 YESLESLTNIFILNLCLSDLVFACLLPVW-ISPYHWGWVLGDFLCKLLNMIFSISLYSSI :.. .. :...:::: ..::.. :: : .. : ::::: ..::. . ...... :.. CCDS30 YKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVH-GWVLGKIMCKITSALYTLNFVSGM 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 FFLTIMTIHRYLSV--VSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGC ::. ..: ::..: : : . : : . . . ::.:.:: :: . .:. : ... CCDS30 QFLACISIDRYVAVTKVPSQSGVGKP---CWI-ICFCVWMAAILLSIPQLVFYTVNDNAR 130 140 150 160 170 180 180 190 200 210 220 pF1KB8 DYSELTWYL-TSVYQHNLFFLLSLGIIL------FCYVEILRTLFRSRSKRRHRTVKLIF . :: ::. .. . .:... :: :::.. . . : .:... CCDS30 CIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLKVLL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 AIVVAYFLSWGPYNFTLFLQTL-FRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLY ..:...... :::.. : ... . ..: ::. ..... :. . ...:. : :.::.:: CCDS30 TVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNPILY 250 260 270 280 290 300 290 300 310 320 330 pF1KB8 VFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY ::.:..:.... .: ... : : : .: CCDS30 VFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI 310 320 330 340 350 >>CCDS2684.1 CCR8 gene_id:1237|Hs108|chr3 (355 aa) initn: 695 init1: 386 opt: 443 Z-score: 414.5 bits: 85.1 E(32554): 9.1e-17 Smith-Waterman score: 747; 36.1% identity (71.1% similar) in 305 aa overlap (10-304:13-317) 10 20 30 40 50 pF1KB8 MESSGNPESTTFFYYDLQSQPCENQ-AWVFATLATTVLYCLVFLLSLVGNSLVLWVL : ..: :. :.::. . . . : .:.:::.:..::.:::::. :: CCDS26 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSS : ..:.:.:....::: ::::.:. .: ::.: .::... .. :..::: CCDS26 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 IFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSG-- .::.:.:.. :::.:: . .:.: :.: . . .:::...:...: .:..: : CCDS26 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV 130 140 150 160 170 180 180 190 200 210 220 pF1KB8 --C----DYSELTWYLTSVYQHNLF-FLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLI : . . : : . . .. :.. .:. . :..:::..::. : : ... . ....:. CCDS26 LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 FAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLY . .:.: .: : :.: .::: .: .:. .: .::: :: . . ..:.::: :::.: CCDS26 LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY 250 260 270 280 290 300 290 300 310 320 330 pF1KB8 VFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY .::: ::. ::...... CCDS26 AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 310 320 330 340 350 333 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:40:16 2016 done: Fri Nov 4 15:40:17 2016 Total Scan time: 2.590 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]