FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8800, 342 aa 1>>>pF1KB8800 342 - 342 aa - 342 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6082+/-0.000558; mu= 20.4850+/- 0.035 mean_var=115.6278+/-28.701, 0's: 0 Z-trim(107.5): 617 B-trim: 809 in 1/49 Lambda= 0.119273 statistics sampled from 14851 (15592) to 14851 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.509), E-opt: 0.2 (0.183), width: 16 Scan time: 6.520 The best scores are: opt bits E(85289) XP_005264866 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 2275 403.4 3.6e-112 NP_006555 (OMIM: 605163) C-X-C chemokine receptor ( 342) 2275 403.4 3.6e-112 XP_011531593 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 2275 403.4 3.6e-112 XP_011531592 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 2275 403.4 3.6e-112 NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 722 136.2 1e-31 NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 722 136.2 1e-31 NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 682 129.4 1.2e-29 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 681 129.2 1.4e-29 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 681 129.2 1.4e-29 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 674 128.0 3.1e-29 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 674 128.0 3.1e-29 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 664 126.3 1e-28 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 664 126.3 1e-28 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 664 126.3 1e-28 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 664 126.3 1e-28 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 663 126.1 1.2e-28 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 663 126.1 1.2e-28 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 645 123.0 1e-27 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 645 123.0 1e-27 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 645 123.0 1e-27 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 645 123.0 1e-27 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 639 122.0 2.1e-27 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 639 122.0 2.1e-27 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 639 122.0 2.2e-27 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 639 122.0 2.2e-27 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 636 121.5 3e-27 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 636 121.5 3e-27 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 614 117.6 3.7e-26 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 605 116.1 1.2e-25 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 589 113.3 7.9e-25 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 589 113.3 7.9e-25 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 589 113.3 7.9e-25 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 589 113.4 8.2e-25 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 567 109.6 1.1e-23 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 564 109.0 1.5e-23 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 564 109.0 1.5e-23 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 556 107.7 4.1e-23 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 556 107.7 4.1e-23 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 556 107.7 4.1e-23 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 556 107.7 4.1e-23 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 556 107.7 4.1e-23 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 556 107.7 4.1e-23 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 553 107.2 5.8e-23 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 553 107.2 5.8e-23 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 553 107.2 5.8e-23 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 553 107.2 5.8e-23 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 553 107.2 5.9e-23 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 553 107.2 5.9e-23 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 553 107.2 6.2e-23 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 553 107.2 6.2e-23 >>XP_005264866 (OMIM: 605163) PREDICTED: C-X-C chemokine (342 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2134.9 bits: 403.4 E(85289): 3.6e-112 Smith-Waterman score: 2275; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW 250 260 270 280 290 300 310 320 330 340 pF1KB8 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL :::::::::::::::::::::::::::::::::::::::::: XP_005 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL 310 320 330 340 >>NP_006555 (OMIM: 605163) C-X-C chemokine receptor type (342 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2134.9 bits: 403.4 E(85289): 3.6e-112 Smith-Waterman score: 2275; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW 250 260 270 280 290 300 310 320 330 340 pF1KB8 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL :::::::::::::::::::::::::::::::::::::::::: NP_006 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL 310 320 330 340 >>XP_011531593 (OMIM: 605163) PREDICTED: C-X-C chemokine (342 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2134.9 bits: 403.4 E(85289): 3.6e-112 Smith-Waterman score: 2275; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW 250 260 270 280 290 300 310 320 330 340 pF1KB8 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL :::::::::::::::::::::::::::::::::::::::::: XP_011 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL 310 320 330 340 >>XP_011531592 (OMIM: 605163) PREDICTED: C-X-C chemokine (342 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2134.9 bits: 403.4 E(85289): 3.6e-112 Smith-Waterman score: 2275; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLIC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFW 250 260 270 280 290 300 310 320 330 340 pF1KB8 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL :::::::::::::::::::::::::::::::::::::::::: XP_011 KLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL 310 320 330 340 >>NP_057641 (OMIM: 606065) atypical chemokine receptor 4 (350 aa) initn: 655 init1: 379 opt: 722 Z-score: 690.5 bits: 136.2 E(85289): 1e-31 Smith-Waterman score: 722; 33.3% identity (67.8% similar) in 354 aa overlap (6-342:12-350) 10 20 30 40 50 pF1KB8 MAEHDYHEDYGFSSFNDSSQEE----HQDFLQFSKVFLPCMYLVVFVCGLVGNS :.:. ... : :: : ..: .:.::::: . .::: ::.::: NP_057 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYT .:..: .:.: .. :::...:: .:::... :::::: ..: ::.:..::: ..:: NP_057 MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 INFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYG .:: ..: .:.::..::...:.:. . .. . . : . . .:. ..:.:.::... NP_057 LNFVSGMQFLACISIDRYVAVTKVPS--QSGVGKPCW--IICFCVWMAAILLSIPQLVFY 130 140 150 160 170 180 190 200 210 220 pF1KB8 NVFNLDKLIC-----GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQ .: : :. : : ...... .. .:: .:.: : ::: . .::.. ... NP_057 TV-N-DNARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIK 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 KHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYT------IMVTEAIAYL : ::... :. ::..::.:.:..:: :. : .:: ... :.:::.:: . NP_057 ISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 RACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTF--SASHNVEAT ..::::.::.:.. .:.. :..: : .:. .... . : .. .: : NP_057 HSCLNPILYVFMGASFKNYVMKVAKKYG---------SWRRQRQSVEEFPFDSEGPTEPT 300 310 320 330 340 340 pF1KB8 SMFQL : :.. NP_057 STFSI 350 >>NP_848540 (OMIM: 606065) atypical chemokine receptor 4 (350 aa) initn: 655 init1: 379 opt: 722 Z-score: 690.5 bits: 136.2 E(85289): 1e-31 Smith-Waterman score: 722; 33.3% identity (67.8% similar) in 354 aa overlap (6-342:12-350) 10 20 30 40 50 pF1KB8 MAEHDYHEDYGFSSFNDSSQEE----HQDFLQFSKVFLPCMYLVVFVCGLVGNS :.:. ... : :: : ..: .:.::::: . .::: ::.::: NP_848 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYT .:..: .:.: .. :::...:: .:::... :::::: ..: ::.:..::: ..:: NP_848 MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 INFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYG .:: ..: .:.::..::...:.:. . .. . . : . . .:. ..:.:.::... NP_848 LNFVSGMQFLACISIDRYVAVTKVPS--QSGVGKPCW--IICFCVWMAAILLSIPQLVFY 130 140 150 160 170 180 190 200 210 220 pF1KB8 NVFNLDKLIC-----GYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQ .: : :. : : ...... .. .:: .:.: : ::: . .::.. ... NP_848 TV-N-DNARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIK 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 KHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYT------IMVTEAIAYL : ::... :. ::..::.:.:..:: :. : .:: ... :.:::.:: . NP_848 ISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 RACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTF--SASHNVEAT ..::::.::.:.. .:.. :..: : .:. .... . : .. .: : NP_848 HSCLNPILYVFMGASFKNYVMKVAKKYG---------SWRRQRQSVEEFPFDSEGPTEPT 300 310 320 330 340 340 pF1KB8 SMFQL : :.. NP_848 STFSI 350 >>NP_001116513 (OMIM: 601267) C-C chemokine receptor typ (374 aa) initn: 541 init1: 383 opt: 682 Z-score: 653.1 bits: 129.4 E(85289): 1.2e-29 Smith-Waterman score: 682; 36.2% identity (73.0% similar) in 293 aa overlap (17-299:27-316) 10 20 30 40 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQ-DFLQFSKVFLPCMYLVVFVCGLVGN : . :. : :.. .:: .: .::. :.::: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 SLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIY ::..: : .::. :::..:.:: ..::.:. :::.::... .:::::..::: . :.: NP_001 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIY :... ..... .:.::....:.: .. .:. .:.: :::.. :......:.: ::. NP_001 HIGYFGGIFFIILLTIDRYLAIVHA--VFALKARTVTFGVVTSVITWLVAVFASVPGIIF 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 GNVFNLDKL-ICG-YHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQK- . . :.. .:: : .. .. . ::. :::: :..::: :.::::. . .: NP_001 TKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 HRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYT------IMVTEAIAYLR ::....:: .: :..: :.:.. .. .: :...... . : .:::.... . NP_001 HRAVRVIFTIMIVYFLFWTPYNIVILL-NTFQEFFGLSNCESTSQLDQATQVTETLGMTH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 ACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMF :.::..::::. :::. : NP_001 CCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKG 300 310 320 330 340 350 >>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r (360 aa) initn: 540 init1: 383 opt: 681 Z-score: 652.3 bits: 129.2 E(85289): 1.4e-29 Smith-Waterman score: 681; 36.1% identity (73.2% similar) in 291 aa overlap (17-297:27-314) 10 20 30 40 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQ-DFLQFSKVFLPCMYLVVFVCGLVGN : . :. : :.. .:: .: .::. :.::: XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 SLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIY ::..: : .::. :::..:.:: ..::.:. :::.::... .:::::..::: . :.: XP_011 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIY :... ..... .:.::....:.:. . .:. .:.: :::.. :......:.: ::. XP_011 HIGYFGGIFFIILLTIDRYLAIVHAV--FALKARTVTFGVVTSVITWLVAVFASVPGIIF 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 GNVFNLDKL-ICG-YHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQK- . . :.. .:: : .. .. . ::. :::: :..::: :.::::. . .: XP_011 TKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 HRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYT------IMVTEAIAYLR ::....:: .: :..: :.:.. .. .: :...... . : .:::.... . XP_011 HRAVRVIFTIMIVYFLFWTPYNIVILL-NTFQEFFGLSNCESTSQLDQATQVTETLGMTH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 ACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMF :.::..::::. :::. XP_011 CCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPSTGEQEVS 300 310 320 330 340 350 >>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ (360 aa) initn: 540 init1: 383 opt: 681 Z-score: 652.3 bits: 129.2 E(85289): 1.4e-29 Smith-Waterman score: 681; 36.1% identity (73.2% similar) in 291 aa overlap (17-297:27-314) 10 20 30 40 pF1KB8 MAEHDYHEDYGFSSFNDSSQEEHQ-DFLQFSKVFLPCMYLVVFVCGLVGN : . :. : :.. .:: .: .::. :.::: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 SLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIY ::..: : .::. :::..:.:: ..::.:. :::.::... .:::::..::: . :.: NP_001 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIY :... ..... .:.::....:.:. . .:. .:.: :::.. :......:.: ::. NP_001 HIGYFGGIFFIILLTIDRYLAIVHAV--FALKARTVTFGVVTSVITWLVAVFASVPGIIF 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 GNVFNLDKL-ICG-YHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQK- . . :.. .:: : .. .. . ::. :::: :..::: :.::::. . .: NP_001 TKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 HRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYT------IMVTEAIAYLR ::....:: .: :..: :.:.. .. .: :...... . : .:::.... . NP_001 HRAVRVIFTIMIVYFLFWTPYNIVILL-NTFQEFFGLSNCESTSQLDQATQVTETLGMTH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 ACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMF :.::..::::. :::. NP_001 CCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPSTGEQEVS 300 310 320 330 340 350 >>NP_003458 (OMIM: 162643,193670) C-X-C chemokine recept (352 aa) initn: 632 init1: 377 opt: 674 Z-score: 645.9 bits: 128.0 E(85289): 3.1e-29 Smith-Waterman score: 683; 33.0% identity (69.8% similar) in 348 aa overlap (5-331:11-352) 10 20 30 40 50 pF1KB8 MAEHDYHEDYGFSSFNDSSQEE--HQDFLQFSKVFLPCMYLVVFVCGLVGNSLV .: :..: ... :: .: ... .:.:.::: .: ..:. :.:::.:: NP_003 MEGISIYTSDNYTEEMGSGDY-DSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTIN ... . .::.:.:: . ..: .:::.:: :::::: .. .: ::. .::.. :::.: NP_003 ILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNV .:.:.:::. :..::....:.::. .:. ... ::. . .:. .::...:..:..:: NP_003 LYSSVLILAFISLDRYLAIVHATN--SQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANV 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 FNLD-KLICG-YHDEAISTVVLATQ-MTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRS . : . :: .. . . .::. : . .:..:: .... :: .::. : :. : ::... NP_003 SEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 LKIIFLVMAVFLLTQMP---------FNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLR :: ... .:. .: : :...:.. :. .. : : .:::.:... NP_003 LKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGC-EFE--NTVHKWISITEALAFFH 240 250 260 270 280 290 290 300 310 320 330 pF1KB8 ACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGV-------SHQWKSSEDNSKTFSASHN ::::.::::.. ::. . . . ... : . .:. :.:..:..: .: NP_003 CCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS 300 310 320 330 340 350 340 pF1KB8 VEATSMFQL 342 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:43:08 2016 done: Fri Nov 4 15:43:09 2016 Total Scan time: 6.520 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]