FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8804, 350 aa 1>>>pF1KB8804 350 - 350 aa - 350 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5419+/-0.000559; mu= 20.8723+/- 0.035 mean_var=122.2270+/-29.991, 0's: 0 Z-trim(106.7): 675 B-trim: 0 in 0/49 Lambda= 0.116009 statistics sampled from 14039 (14804) to 14039 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.508), E-opt: 0.2 (0.174), width: 16 Scan time: 6.440 The best scores are: opt bits E(85289) NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 2317 400.1 3.8e-111 NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 2317 400.1 3.8e-111 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 841 153.1 9e-37 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 841 153.1 9e-37 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 841 153.1 9e-37 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 841 153.1 9.1e-37 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 837 152.4 1.4e-36 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 837 152.4 1.4e-36 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 830 151.2 3.2e-36 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 830 151.2 3.2e-36 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 729 134.3 3.6e-31 XP_011531593 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 722 133.1 8.5e-31 XP_005264866 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 722 133.1 8.5e-31 XP_011531592 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 722 133.1 8.5e-31 NP_006555 (OMIM: 605163) C-X-C chemokine receptor ( 342) 722 133.1 8.5e-31 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 718 132.5 1.4e-30 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 718 132.5 1.4e-30 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 708 130.8 4.4e-30 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 708 130.8 4.4e-30 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 708 130.8 4.4e-30 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 708 130.8 4.4e-30 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 708 130.8 4.4e-30 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 708 130.8 4.4e-30 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 685 127.0 6.7e-29 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 684 126.8 7.1e-29 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 684 126.8 7.1e-29 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 684 126.8 7.1e-29 NP_057686 (OMIM: 600240) C-C chemokine receptor ty ( 362) 681 126.3 1e-28 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 679 126.0 1.3e-28 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 676 125.5 1.8e-28 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 669 124.3 4.1e-28 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 661 123.0 1e-27 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 661 123.0 1e-27 NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 656 122.1 1.8e-27 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 655 122.0 2.1e-27 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 655 122.0 2.1e-27 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 655 122.1 2.2e-27 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 655 122.1 2.2e-27 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 653 121.6 2.6e-27 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 653 121.6 2.6e-27 NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 646 120.5 6e-27 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 645 120.3 6.6e-27 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 629 117.6 4.2e-26 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 623 116.6 8.5e-26 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 623 116.6 8.5e-26 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 623 116.6 8.5e-26 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 623 116.6 8.5e-26 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 623 116.6 8.7e-26 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 623 116.6 8.7e-26 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 623 116.7 9.1e-26 >>NP_057641 (OMIM: 606065) atypical chemokine receptor 4 (350 aa) initn: 2317 init1: 2317 opt: 2317 Z-score: 2116.5 bits: 400.1 E(85289): 3.8e-111 Smith-Waterman score: 2317; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KB8 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LNFVSGMQFLACISIDRYVAVTKVPSQSGVGKPCWIICFCVWMAAILLSIPQLVFYTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LNFVSGMQFLACISIDRYVAVTKVPSQSGVGKPCWIICFCVWMAAILLSIPQLVFYTVND 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 NARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNP 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 ILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI :::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI 310 320 330 340 350 >>NP_848540 (OMIM: 606065) atypical chemokine receptor 4 (350 aa) initn: 2317 init1: 2317 opt: 2317 Z-score: 2116.5 bits: 400.1 E(85289): 3.8e-111 Smith-Waterman score: 2317; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KB8 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LNFVSGMQFLACISIDRYVAVTKVPSQSGVGKPCWIICFCVWMAAILLSIPQLVFYTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 LNFVSGMQFLACISIDRYVAVTKVPSQSGVGKPCWIICFCVWMAAILLSIPQLVFYTVND 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 NARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 VLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNP 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 ILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI :::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 ILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI 310 320 330 340 350 >>NP_001288646 (OMIM: 600242) C-C chemokine receptor typ (372 aa) initn: 810 init1: 456 opt: 841 Z-score: 781.2 bits: 153.1 E(85289): 9e-37 Smith-Waterman score: 845; 39.4% identity (69.8% similar) in 358 aa overlap (3-349:17-371) 10 20 30 40 pF1KB8 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPV : :.. :: : .: : ::. .: .: :.:::.: :::. NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNT---TVDYTLFESLCSKKDVRNFKAWFLPI 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 FLTIVFVIGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWV . .:. .:: ::..:: : :.:. .: ::.:.:::::::.:.:.:::::: .:...:: NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 LGKIMCKITSALYTLNFVSGMQFLACISIDRYVAVTKVPS----QSGVGKPCWIICFCVW .: .::. :.: ..: ::: .: :::::::::.... : .. : . : .: NP_001 FGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 MAAILLSIPQLVFYTVNDNARCIPIFPRYLGTSMKALI--QMLEICIGFVVPFLIMGVCY . : .::::.:.. .. .. . . ..:.: :. .. :::.::.: :. :: NP_001 ILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCY 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 FITARTLMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKR .. :::.. :.. .. .::...::.:::: ::::: : . ... . ..:..::. NP_001 LVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQ 240 250 260 270 280 290 290 300 310 320 330 pF1KB8 MDIAIQVTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYG--SWRRQRQ--SVEEFPF ..:: .:: :.: . :.::.::.:.:..:.: ..:. : : : .. :: : ... NP_001 LNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRR 300 310 320 330 340 350 340 350 pF1KB8 DSEG-PTEPTSTFSI .: . .: :.::: NP_001 SSMSVEAETTTTFSP 360 370 >>NP_001288645 (OMIM: 600242) C-C chemokine receptor typ (372 aa) initn: 810 init1: 456 opt: 841 Z-score: 781.2 bits: 153.1 E(85289): 9e-37 Smith-Waterman score: 845; 39.4% identity (69.8% similar) in 358 aa overlap (3-349:17-371) 10 20 30 40 pF1KB8 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPV : :.. :: : .: : ::. .: .: :.:::.: :::. NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNT---TVDYTLFESLCSKKDVRNFKAWFLPI 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 FLTIVFVIGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWV . .:. .:: ::..:: : :.:. .: ::.:.:::::::.:.:.:::::: .:...:: NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 LGKIMCKITSALYTLNFVSGMQFLACISIDRYVAVTKVPS----QSGVGKPCWIICFCVW .: .::. :.: ..: ::: .: :::::::::.... : .. : . : .: NP_001 FGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 MAAILLSIPQLVFYTVNDNARCIPIFPRYLGTSMKALI--QMLEICIGFVVPFLIMGVCY . : .::::.:.. .. .. . . ..:.: :. .. :::.::.: :. :: NP_001 ILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCY 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 FITARTLMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKR .. :::.. :.. .. .::...::.:::: ::::: : . ... . ..:..::. NP_001 LVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQ 240 250 260 270 280 290 290 300 310 320 330 pF1KB8 MDIAIQVTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYG--SWRRQRQ--SVEEFPF ..:: .:: :.: . :.::.::.:.:..:.: ..:. : : : .. :: : ... NP_001 LNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRR 300 310 320 330 340 350 340 350 pF1KB8 DSEG-PTEPTSTFSI .: . .: :.::: NP_001 SSMSVEAETTTTFSP 360 370 >>NP_001288647 (OMIM: 600242) C-C chemokine receptor typ (372 aa) initn: 810 init1: 456 opt: 841 Z-score: 781.2 bits: 153.1 E(85289): 9e-37 Smith-Waterman score: 845; 39.4% identity (69.8% similar) in 358 aa overlap (3-349:17-371) 10 20 30 40 pF1KB8 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPV : :.. :: : .: : ::. .: .: :.:::.: :::. NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNT---TVDYTLFESLCSKKDVRNFKAWFLPI 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 FLTIVFVIGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWV . .:. .:: ::..:: : :.:. .: ::.:.:::::::.:.:.:::::: .:...:: NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 LGKIMCKITSALYTLNFVSGMQFLACISIDRYVAVTKVPS----QSGVGKPCWIICFCVW .: .::. :.: ..: ::: .: :::::::::.... : .. : . : .: NP_001 FGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 MAAILLSIPQLVFYTVNDNARCIPIFPRYLGTSMKALI--QMLEICIGFVVPFLIMGVCY . : .::::.:.. .. .. . . ..:.: :. .. :::.::.: :. :: NP_001 ILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCY 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 FITARTLMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKR .. :::.. :.. .. .::...::.:::: ::::: : . ... . ..:..::. NP_001 LVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQ 240 250 260 270 280 290 290 300 310 320 330 pF1KB8 MDIAIQVTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYG--SWRRQRQ--SVEEFPF ..:: .:: :.: . :.::.::.:.:..:.: ..:. : : : .. :: : ... NP_001 LNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRR 300 310 320 330 340 350 340 350 pF1KB8 DSEG-PTEPTSTFSI .: . .: :.::: NP_001 SSMSVEAETTTTFSP 360 370 >>NP_001829 (OMIM: 600242) C-C chemokine receptor type 7 (378 aa) initn: 810 init1: 456 opt: 841 Z-score: 781.1 bits: 153.1 E(85289): 9.1e-37 Smith-Waterman score: 845; 39.4% identity (69.8% similar) in 358 aa overlap (3-349:23-377) 10 20 30 40 pF1KB8 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFA : :.. :: : .: : ::. .: .: :.:::.: NP_001 MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNT---TVDYTLFESLCSKKDVRNFK 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 KVFLPVFLTIVFVIGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVN :::.. .:. .:: ::..:: : :.:. .: ::.:.:::::::.:.:.:::::: . NP_001 AWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYS 60 70 80 90 100 110 110 120 130 140 150 pF1KB8 AVHGWVLGKIMCKITSALYTLNFVSGMQFLACISIDRYVAVTKVPS----QSGVGKPCWI :...::.: .::. :.: ..: ::: .: :::::::::.... : .. : . NP_001 AAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB8 ICFCVWMAAILLSIPQLVFYTVNDNARCIPIFPRYLGTSMKALI--QMLEICIGFVVPFL : .:. : .::::.:.. .. .. . . ..:.: :. .. :::.::.: NP_001 SCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 IMGVCYFITARTLMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITS :. ::.. :::.. :.. .. .::...::.:::: ::::: : . ... . .. NP_001 AMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSST 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 CNMSKRMDIAIQVTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYG--SWRRQRQ--S :..::...:: .:: :.: . :.::.::.:.:..:.: ..:. : : : .. :: : NP_001 CELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSS 300 310 320 330 340 350 340 350 pF1KB8 VEEFPFDSEG-PTEPTSTFSI ... .: . .: :.::: NP_001 CRHIRRSSMSVEAETTTTFSP 360 370 >>XP_011531614 (OMIM: 604738) PREDICTED: C-C chemokine r (369 aa) initn: 808 init1: 380 opt: 837 Z-score: 777.6 bits: 152.4 E(85289): 1.4e-36 Smith-Waterman score: 837; 36.6% identity (68.9% similar) in 325 aa overlap (6-322:12-336) 10 20 30 40 50 pF1KB8 MALEQNQSTDYYYEE-NEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFV :.. :: : . :. ... .. : :..::.::. ::: . .::. XP_011 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 IGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCK .: :::.:. .: : . .: ::...::::.::::.: ::::::. :. : . .::: XP_011 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 ITSALYTLNFVSGMQFLACISIDRYVAVTKVPSQSGVGKP----CWIICFCVWMAAILLS .....: .:: : . .. :::.:::.:.... . ..:: .:. : : XP_011 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 IPQLVFYTVNDN---ARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITART ::.... .... : : ..: .:..:. . :.. .:: .::..:. :: : .: XP_011 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQ :.. . . . ::: .::. ::...:.::: . . ..:: .:..: .: .:: .: XP_011 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 VTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTS ::..::.:::::::.::::.: :. ..:. :. : XP_011 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL 310 320 330 340 350 360 350 pF1KB8 TFSI XP_011 ETTSGALSL >>NP_112477 (OMIM: 604738) C-C chemokine receptor type 9 (369 aa) initn: 808 init1: 380 opt: 837 Z-score: 777.6 bits: 152.4 E(85289): 1.4e-36 Smith-Waterman score: 837; 36.6% identity (68.9% similar) in 325 aa overlap (6-322:12-336) 10 20 30 40 50 pF1KB8 MALEQNQSTDYYYEE-NEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFV :.. :: : . :. ... .. : :..::.::. ::: . .::. NP_112 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 IGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCK .: :::.:. .: : . .: ::...::::.::::.: ::::::. :. : . .::: NP_112 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 ITSALYTLNFVSGMQFLACISIDRYVAVTKVPSQSGVGKP----CWIICFCVWMAAILLS .....: .:: : . .. :::.:::.:.... . ..:: .:. : : NP_112 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 IPQLVFYTVNDN---ARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITART ::.... .... : : ..: .:..:. . :.. .:: .::..:. :: : .: NP_112 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQ :.. . . . ::: .::. ::...:.::: . . ..:: .:..: .: .:: .: NP_112 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 VTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTS ::..::.:::::::.::::.: :. ..:. :. : NP_112 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL 310 320 330 340 350 360 350 pF1KB8 TFSI NP_112 ETTSGALSL >>NP_001243298 (OMIM: 604738) C-C chemokine receptor typ (357 aa) initn: 808 init1: 380 opt: 830 Z-score: 771.4 bits: 151.2 E(85289): 3.2e-36 Smith-Waterman score: 830; 36.8% identity (68.8% similar) in 321 aa overlap (10-322:4-324) 10 20 30 40 50 pF1KB8 MALEQNQSTDYYYEE-NEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGN :: : . :. ... .. : :..::.::. ::: . .::..: :: NP_001 MADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 SMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALY :.:. .: : . .: ::...::::.::::.: ::::::. :. : . .:::.....: NP_001 SLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 TLNFVSGMQFLACISIDRYVAVTKVPSQSGVGKP----CWIICFCVWMAAILLSIPQLVF .:: : . .. :::.:::.:.... . ..:: .:. : : ::.... NP_001 KMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 YTVNDN---ARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPN .... : : ..: .:..:. . :.. .:: .::..:. :: : .::.. . NP_001 SQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 IKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIA . . ::: .::. ::...:.::: . . ..:: .:..: .: .:: .:::..:: NP_001 SSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 LFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI .:::::::.::::.: :. ..:. :. : NP_001 FFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGA 300 310 320 330 340 350 >>NP_006632 (OMIM: 604738) C-C chemokine receptor type 9 (357 aa) initn: 808 init1: 380 opt: 830 Z-score: 771.4 bits: 151.2 E(85289): 3.2e-36 Smith-Waterman score: 830; 36.8% identity (68.8% similar) in 321 aa overlap (10-322:4-324) 10 20 30 40 50 pF1KB8 MALEQNQSTDYYYEE-NEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGN :: : . :. ... .. : :..::.::. ::: . .::..: :: NP_006 MADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 SMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALY :.:. .: : . .: ::...::::.::::.: ::::::. :. : . .:::.....: NP_006 SLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 TLNFVSGMQFLACISIDRYVAVTKVPSQSGVGKP----CWIICFCVWMAAILLSIPQLVF .:: : . .. :::.:::.:.... . ..:: .:. : : ::.... NP_006 KMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 YTVNDN---ARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPN .... : : ..: .:..:. . :.. .:: .::..:. :: : .::.. . NP_006 SQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 IKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIA . . ::: .::. ::...:.::: . . ..:: .:..: .: .:: .:::..:: NP_006 SSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 LFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI .:::::::.::::.: :. ..:. :. : NP_006 FFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGA 300 310 320 330 340 350 350 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:40:28 2016 done: Sat Nov 5 09:40:29 2016 Total Scan time: 6.440 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]