FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8805, 351 aa 1>>>pF1KB8805 351 - 351 aa - 351 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3687+/-0.000707; mu= 16.5399+/- 0.043 mean_var=72.6505+/-14.481, 0's: 0 Z-trim(110.8): 7 B-trim: 0 in 0/52 Lambda= 0.150472 statistics sampled from 11875 (11879) to 11875 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.365), width: 16 Scan time: 2.870 The best scores are: opt bits E(32554) CCDS32093.1 TMEM30B gene_id:161291|Hs108|chr14 ( 351) 2479 546.9 9.1e-156 CCDS4983.1 TMEM30A gene_id:55754|Hs108|chr6 ( 361) 1243 278.6 5.5e-75 CCDS47453.1 TMEM30A gene_id:55754|Hs108|chr6 ( 325) 930 210.6 1.4e-54 >>CCDS32093.1 TMEM30B gene_id:161291|Hs108|chr14 (351 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 2910.0 bits: 546.9 E(32554): 9.1e-156 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB8 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE 310 320 330 340 350 >>CCDS4983.1 TMEM30A gene_id:55754|Hs108|chr6 (361 aa) initn: 1197 init1: 342 opt: 1243 Z-score: 1459.7 bits: 278.6 E(32554): 5.5e-75 Smith-Waterman score: 1243; 53.4% identity (76.1% similar) in 343 aa overlap (6-347:22-355) 10 20 30 40 pF1KB8 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGL ::. ...:::::: :::::::::.:.:. .::.:: :: CCDS49 MAMNYNAKDEVDGGPPCAPGGTAK-TRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGL 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 AFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELF :: .:.:.. .::.:.:.: :::: .. :. : . :: :. :.: . : CCDS49 IFIPIGIGIFVTSNNIREIEIDYTGTEPSSPCNKCLSPDV-----TPCFCTINFTLEKSF 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 QGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGA .: :..:: :.:::::.::: ::::.::.: ::: .: .:: ::.:. ::::::: CCDS49 EGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDSSALLNPSKECEPYRRNEDK-PIAPCGA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 IANSLFNDSFSLWHQRQPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTA ::::.:::.. :. . . : . . : ..::::::: .::::::: . .: :.::. CCDS49 IANSMFNDTLELFLIGNDSYP-IPIALKKKGIAWWTDKNVKFRNPPG-GDNLEERFKGTT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 PPPNWRRPVYELSPDPNNTGFINQDFVVWMRTAALPTFRKLYARI-RQGNYSAGLPRGAY : :: .::: :. ::.:.::::.::.::::::::::::::: : :... :: : : CCDS49 KPVNWLKPVYMLDSDPDNNGFINEDFIVWMRTAALPTFRKLYRLIERKSDLHPTLPAGRY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 RVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQ .:.::::::. : :.: .:.:.:::::::::::::::..:::. .: : :.::. .:. CCDS49 SLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYR 300 310 320 330 340 350 350 pF1KB8 DQDDDDEE .... CCDS49 NSSNTADITI 360 >>CCDS47453.1 TMEM30A gene_id:55754|Hs108|chr6 (325 aa) initn: 1080 init1: 342 opt: 930 Z-score: 1093.1 bits: 210.6 E(32554): 1.4e-54 Smith-Waterman score: 1080; 49.9% identity (70.3% similar) in 343 aa overlap (6-347:22-319) 10 20 30 40 pF1KB8 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGL ::. ...:::::: :::::::::.:.:. .::.:: :: CCDS47 MAMNYNAKDEVDGGPPCAPGGTAK-TRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGL 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 AFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELF :: .:.:.. .::.:.:.: CCDS47 IFIPIGIGIFVTSNNIREIE---------------------------------------- 60 70 110 120 130 140 150 160 pF1KB8 QGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGA : :..:: :.:::::.::: ::::.::.: ::: .: .:: ::.:. ::::::: CCDS47 -GNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDSSALLNPSKECEPYRRNEDK-PIAPCGA 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB8 IANSLFNDSFSLWHQRQPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTA ::::.:::.. :. . . : . . : ..::::::: .::::::: . .: :.::. CCDS47 IANSMFNDTLELFLIGNDSYP-IPIALKKKGIAWWTDKNVKFRNPPG-GDNLEERFKGTT 140 150 160 170 180 190 230 240 250 260 270 280 pF1KB8 PPPNWRRPVYELSPDPNNTGFINQDFVVWMRTAALPTFRKLYARI-RQGNYSAGLPRGAY : :: .::: :. ::.:.::::.::.::::::::::::::: : :... :: : : CCDS47 KPVNWLKPVYMLDSDPDNNGFINEDFIVWMRTAALPTFRKLYRLIERKSDLHPTLPAGRY 200 210 220 230 240 250 290 300 310 320 330 340 pF1KB8 RVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQ .:.::::::. : :.: .:.:.:::::::::::::::..:::. .: : :.::. .:. CCDS47 SLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYR 260 270 280 290 300 310 350 pF1KB8 DQDDDDEE .... CCDS47 NSSNTADITI 320 351 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:44:20 2016 done: Fri Nov 4 15:44:20 2016 Total Scan time: 2.870 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]