FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8805, 351 aa 1>>>pF1KB8805 351 - 351 aa - 351 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1923+/-0.000317; mu= 17.6908+/- 0.020 mean_var=75.2693+/-15.412, 0's: 0 Z-trim(117.6): 4 B-trim: 153 in 1/57 Lambda= 0.147831 statistics sampled from 29819 (29822) to 29819 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.35), width: 16 Scan time: 6.380 The best scores are: opt bits E(85289) NP_001017970 (OMIM: 611029) cell cycle control pro ( 351) 2479 537.7 1.4e-152 NP_060717 (OMIM: 611028) cell cycle control protei ( 361) 1243 274.1 3.3e-73 NP_001137430 (OMIM: 611028) cell cycle control pro ( 325) 930 207.3 3.8e-53 >>NP_001017970 (OMIM: 611029) cell cycle control protein (351 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 2860.1 bits: 537.7 E(85289): 1.4e-152 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB8 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE 310 320 330 340 350 >>NP_060717 (OMIM: 611028) cell cycle control protein 50 (361 aa) initn: 1197 init1: 342 opt: 1243 Z-score: 1435.3 bits: 274.1 E(85289): 3.3e-73 Smith-Waterman score: 1243; 53.4% identity (76.1% similar) in 343 aa overlap (6-347:22-355) 10 20 30 40 pF1KB8 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGL ::. ...:::::: :::::::::.:.:. .::.:: :: NP_060 MAMNYNAKDEVDGGPPCAPGGTAK-TRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGL 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 AFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELF :: .:.:.. .::.:.:.: :::: .. :. : . :: :. :.: . : NP_060 IFIPIGIGIFVTSNNIREIEIDYTGTEPSSPCNKCLSPDV-----TPCFCTINFTLEKSF 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 QGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGA .: :..:: :.:::::.::: ::::.::.: ::: .: .:: ::.:. ::::::: NP_060 EGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDSSALLNPSKECEPYRRNEDK-PIAPCGA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 IANSLFNDSFSLWHQRQPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTA ::::.:::.. :. . . : . . : ..::::::: .::::::: . .: :.::. NP_060 IANSMFNDTLELFLIGNDSYP-IPIALKKKGIAWWTDKNVKFRNPPG-GDNLEERFKGTT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 PPPNWRRPVYELSPDPNNTGFINQDFVVWMRTAALPTFRKLYARI-RQGNYSAGLPRGAY : :: .::: :. ::.:.::::.::.::::::::::::::: : :... :: : : NP_060 KPVNWLKPVYMLDSDPDNNGFINEDFIVWMRTAALPTFRKLYRLIERKSDLHPTLPAGRY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 RVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQ .:.::::::. : :.: .:.:.:::::::::::::::..:::. .: : :.::. .:. NP_060 SLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYR 300 310 320 330 340 350 350 pF1KB8 DQDDDDEE .... NP_060 NSSNTADITI 360 >>NP_001137430 (OMIM: 611028) cell cycle control protein (325 aa) initn: 1080 init1: 342 opt: 930 Z-score: 1075.1 bits: 207.3 E(85289): 3.8e-53 Smith-Waterman score: 1080; 49.9% identity (70.3% similar) in 343 aa overlap (6-347:22-319) 10 20 30 40 pF1KB8 MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGL ::. ...:::::: :::::::::.:.:. .::.:: :: NP_001 MAMNYNAKDEVDGGPPCAPGGTAK-TRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGL 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 AFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELF :: .:.:.. .::.:.:.: NP_001 IFIPIGIGIFVTSNNIREIE---------------------------------------- 60 70 110 120 130 140 150 160 pF1KB8 QGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGA : :..:: :.:::::.::: ::::.::.: ::: .: .:: ::.:. ::::::: NP_001 -GNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDSSALLNPSKECEPYRRNEDK-PIAPCGA 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB8 IANSLFNDSFSLWHQRQPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTA ::::.:::.. :. . . : . . : ..::::::: .::::::: . .: :.::. NP_001 IANSMFNDTLELFLIGNDSYP-IPIALKKKGIAWWTDKNVKFRNPPG-GDNLEERFKGTT 140 150 160 170 180 190 230 240 250 260 270 280 pF1KB8 PPPNWRRPVYELSPDPNNTGFINQDFVVWMRTAALPTFRKLYARI-RQGNYSAGLPRGAY : :: .::: :. ::.:.::::.::.::::::::::::::: : :... :: : : NP_001 KPVNWLKPVYMLDSDPDNNGFINEDFIVWMRTAALPTFRKLYRLIERKSDLHPTLPAGRY 200 210 220 230 240 250 290 300 310 320 330 340 pF1KB8 RVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQ .:.::::::. : :.: .:.:.:::::::::::::::..:::. .: : :.::. .:. NP_001 SLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYR 260 270 280 290 300 310 350 pF1KB8 DQDDDDEE .... NP_001 NSSNTADITI 320 351 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:44:21 2016 done: Fri Nov 4 15:44:22 2016 Total Scan time: 6.380 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]