FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8810, 361 aa 1>>>pF1KB8810 361 - 361 aa - 361 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9670+/-0.000492; mu= 18.0468+/- 0.031 mean_var=81.7201+/-20.833, 0's: 0 Z-trim(108.5): 649 B-trim: 1537 in 2/47 Lambda= 0.141876 statistics sampled from 15789 (16555) to 15789 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.539), E-opt: 0.2 (0.194), width: 16 Scan time: 6.970 The best scores are: opt bits E(85289) XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 2407 503.2 3.7e-142 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 2407 503.2 3.7e-142 NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 595 132.3 1.6e-30 NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 595 132.3 1.6e-30 NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 595 132.3 1.6e-30 NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 595 132.3 1.6e-30 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 595 132.3 1.6e-30 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 595 132.3 1.6e-30 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 595 132.3 1.6e-30 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 578 128.8 1.9e-29 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 578 128.8 1.9e-29 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 578 128.8 1.9e-29 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 578 128.8 1.9e-29 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 578 128.8 1.9e-29 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 578 128.8 1.9e-29 NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 536 120.2 7.4e-27 NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 530 119.0 1.6e-26 NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 530 119.0 1.6e-26 NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 531 119.3 1.6e-26 NP_115942 (OMIM: 300903) probable G-protein couple ( 333) 525 117.9 3.2e-26 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 524 117.8 3.9e-26 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 524 117.8 3.9e-26 XP_005272654 (OMIM: 300241) PREDICTED: probable G- ( 381) 524 117.8 4.1e-26 NP_001091048 (OMIM: 300241) probable G-protein cou ( 381) 524 117.8 4.1e-26 NP_005291 (OMIM: 300241) probable G-protein couple ( 381) 524 117.8 4.1e-26 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 524 117.8 4.1e-26 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 524 117.8 4.2e-26 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 524 117.8 4.2e-26 XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 523 117.6 4.5e-26 XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 523 117.6 4.5e-26 XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 523 117.6 4.5e-26 XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 523 117.6 4.5e-26 XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 523 117.6 4.5e-26 NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 523 117.6 4.5e-26 XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 523 117.6 4.5e-26 XP_016862558 (OMIM: 600515,609821) PREDICTED: P2Y ( 342) 522 117.3 5e-26 NP_795345 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 522 117.3 5e-26 NP_073625 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 522 117.3 5e-26 XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 523 117.7 6.1e-26 XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 523 117.7 6.1e-26 NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 520 117.0 7.2e-26 NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 520 117.0 7.2e-26 NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 520 117.0 7.2e-26 XP_016873328 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 515 115.9 1.5e-25 >>XP_016875894 (OMIM: 605741) PREDICTED: G-protein coupl (361 aa) initn: 2407 init1: 2407 opt: 2407 Z-score: 2673.1 bits: 503.2 E(85289): 3.7e-142 Smith-Waterman score: 2407; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KB8 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG 310 320 330 340 350 360 pF1KB8 K : XP_016 K >>NP_004942 (OMIM: 605741) G-protein coupled receptor 18 (361 aa) initn: 2407 init1: 2407 opt: 2407 Z-score: 2673.1 bits: 503.2 E(85289): 3.7e-142 Smith-Waterman score: 2407; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KB8 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG 310 320 330 340 350 360 pF1KB8 K : NP_004 K >>NP_001269116 (OMIM: 300201) cysteinyl leukotriene rece (337 aa) initn: 518 init1: 360 opt: 595 Z-score: 669.0 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 29.3% identity (67.5% similar) in 311 aa overlap (38-346:30-334) 10 20 30 40 50 60 pF1KB8 NFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTT ::.. ..:. :: ..: :.... .: .. NP_001 MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSI .: ::...:.: . .:: :..::. : .:: :::... ..:.: : .. ::: .:. NP_001 VYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 DRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNF : ::.: :.. .. ..:. ::. .::.:. . :.:. .:.: . :.: :. NP_001 FRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 EETKSLPWIL-LGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTI ..::. .: . :.:...:..::..::..: :.. . .. :. .:::.. : NP_001 NQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSS----HKKAIGMI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 ILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPF ... ..:.. : :::. :. .. .. :.. .: :. .:. : :::.::. NP_001 MVVTAAFLVSFMPYHIQRTIHL--HFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 IYFFACKGYKRKVMRMLKRQVS-VSISSAVKSAPEENSREMTETQMMIHSKSSNGK .:::. ...... . :...: :. :.. :...:. NP_001 LYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV 300 310 320 330 >>NP_006630 (OMIM: 300201) cysteinyl leukotriene recepto (337 aa) initn: 518 init1: 360 opt: 595 Z-score: 669.0 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 29.3% identity (67.5% similar) in 311 aa overlap (38-346:30-334) 10 20 30 40 50 60 pF1KB8 NFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTT ::.. ..:. :: ..: :.... .: .. NP_006 MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSI .: ::...:.: . .:: :..::. : .:: :::... ..:.: : .. ::: .:. NP_006 VYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 DRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNF : ::.: :.. .. ..:. ::. .::.:. . :.:. .:.: . :.: :. NP_006 FRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 EETKSLPWIL-LGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTI ..::. .: . :.:...:..::..::..: :.. . .. :. .:::.. : NP_006 NQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSS----HKKAIGMI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 ILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPF ... ..:.. : :::. :. .. .. :.. .: :. .:. : :::.::. NP_006 MVVTAAFLVSFMPYHIQRTIHL--HFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 IYFFACKGYKRKVMRMLKRQVS-VSISSAVKSAPEENSREMTETQMMIHSKSSNGK .:::. ...... . :...: :. :.. :...:. NP_006 LYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV 300 310 320 330 >>NP_001269117 (OMIM: 300201) cysteinyl leukotriene rece (337 aa) initn: 518 init1: 360 opt: 595 Z-score: 669.0 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 29.3% identity (67.5% similar) in 311 aa overlap (38-346:30-334) 10 20 30 40 50 60 pF1KB8 NFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTT ::.. ..:. :: ..: :.... .: .. NP_001 MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSI .: ::...:.: . .:: :..::. : .:: :::... ..:.: : .. ::: .:. NP_001 VYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 DRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNF : ::.: :.. .. ..:. ::. .::.:. . :.:. .:.: . :.: :. NP_001 FRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 EETKSLPWIL-LGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTI ..::. .: . :.:...:..::..::..: :.. . .. :. .:::.. : NP_001 NQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSS----HKKAIGMI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 ILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPF ... ..:.. : :::. :. .. .. :.. .: :. .:. : :::.::. NP_001 MVVTAAFLVSFMPYHIQRTIHL--HFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 IYFFACKGYKRKVMRMLKRQVS-VSISSAVKSAPEENSREMTETQMMIHSKSSNGK .:::. ...... . :...: :. :.. :...:. NP_001 LYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV 300 310 320 330 >>NP_001269115 (OMIM: 300201) cysteinyl leukotriene rece (337 aa) initn: 518 init1: 360 opt: 595 Z-score: 669.0 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 29.3% identity (67.5% similar) in 311 aa overlap (38-346:30-334) 10 20 30 40 50 60 pF1KB8 NFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTT ::.. ..:. :: ..: :.... .: .. NP_001 MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSI .: ::...:.: . .:: :..::. : .:: :::... ..:.: : .. ::: .:. NP_001 VYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 DRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNF : ::.: :.. .. ..:. ::. .::.:. . :.:. .:.: . :.: :. NP_001 FRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 EETKSLPWIL-LGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTI ..::. .: . :.:...:..::..::..: :.. . .. :. .:::.. : NP_001 NQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSS----HKKAIGMI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 ILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPF ... ..:.. : :::. :. .. .. :.. .: :. .:. : :::.::. NP_001 MVVTAAFLVSFMPYHIQRTIHL--HFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 IYFFACKGYKRKVMRMLKRQVS-VSISSAVKSAPEENSREMTETQMMIHSKSSNGK .:::. ...... . :...: :. :.. :...:. NP_001 LYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV 300 310 320 330 >>NP_001155970 (OMIM: 278150,609239) lysophosphatidic ac (344 aa) initn: 539 init1: 300 opt: 595 Z-score: 668.9 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 31.3% identity (66.3% similar) in 297 aa overlap (19-310:5-293) 10 20 30 40 50 60 pF1KB8 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR :. . . : .. .:.::..::..: .:. ... NP_001 MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVL 10 20 30 40 70 80 90 100 110 120 pF1KB8 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN : : :: : ::..::.::. .:: :: :.. .: .:: ::.:....:: : :... NP_001 KVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSIL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT :.::.:.:::.:.:.:.. . .. ..:: :: ::. :.. . : .. ...... . NP_001 FLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNAS 110 120 130 140 150 160 190 200 210 220 230 pF1KB8 CMEYPNFEET--KS-LPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLT-EKS . :: :. :. : :.. ..:. .:::. . : :.. : . :.: .: NP_001 EACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTK-----PVTLSRS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 GVNK-KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVC .:: :.:. :.. ...: .::.::.. .: . . .: ..:..:: . . .:.: NP_001 KINKTKVLKMIFVHLIIFCFCFVPYNINLILYSL--VRTQTFVNCSVVAAVRTMYPITLC 230 240 250 260 270 300 310 320 330 340 350 pF1KB8 LMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHS . :::.::..:.: NP_001 IAVSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIF 280 290 300 310 320 330 >>NP_001155969 (OMIM: 278150,609239) lysophosphatidic ac (344 aa) initn: 539 init1: 300 opt: 595 Z-score: 668.9 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 31.3% identity (66.3% similar) in 297 aa overlap (19-310:5-293) 10 20 30 40 50 60 pF1KB8 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR :. . . : .. .:.::..::..: .:. ... NP_001 MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVL 10 20 30 40 70 80 90 100 110 120 pF1KB8 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN : : :: : ::..::.::. .:: :: :.. .: .:: ::.:....:: : :... NP_001 KVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSIL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT :.::.:.:::.:.:.:.. . .. ..:: :: ::. :.. . : .. ...... . NP_001 FLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNAS 110 120 130 140 150 160 190 200 210 220 230 pF1KB8 CMEYPNFEET--KS-LPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLT-EKS . :: :. :. : :.. ..:. .:::. . : :.. : . :.: .: NP_001 EACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTK-----PVTLSRS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 GVNK-KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVC .:: :.:. :.. ...: .::.::.. .: . . .: ..:..:: . . .:.: NP_001 KINKTKVLKMIFVHLIIFCFCFVPYNINLILYSL--VRTQTFVNCSVVAAVRTMYPITLC 230 240 250 260 270 300 310 320 330 340 350 pF1KB8 LMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHS . :::.::..:.: NP_001 IAVSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIF 280 290 300 310 320 330 >>NP_005758 (OMIM: 278150,609239) lysophosphatidic acid (344 aa) initn: 539 init1: 300 opt: 595 Z-score: 668.9 bits: 132.3 E(85289): 1.6e-30 Smith-Waterman score: 595; 31.3% identity (66.3% similar) in 297 aa overlap (19-310:5-293) 10 20 30 40 50 60 pF1KB8 MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR :. . . : .. .:.::..::..: .:. ... NP_005 MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVL 10 20 30 40 70 80 90 100 110 120 pF1KB8 KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN : : :: : ::..::.::. .:: :: :.. .: .:: ::.:....:: : :... NP_005 KVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSIL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT :.::.:.:::.:.:.:.. . .. ..:: :: ::. :.. . : .. ...... . NP_005 FLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNAS 110 120 130 140 150 160 190 200 210 220 230 pF1KB8 CMEYPNFEET--KS-LPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLT-EKS . :: :. :. : :.. ..:. .:::. . : :.. : . :.: .: NP_005 EACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTK-----PVTLSRS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 GVNK-KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVC .:: :.:. :.. ...: .::.::.. .: . . .: ..:..:: . . .:.: NP_005 KINKTKVLKMIFVHLIIFCFCFVPYNINLILYSL--VRTQTFVNCSVVAAVRTMYPITLC 230 240 250 260 270 300 310 320 330 340 350 pF1KB8 LMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHS . :::.::..:.: NP_005 IAVSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIF 280 290 300 310 320 330 >>XP_006724702 (OMIM: 300086) PREDICTED: lysophosphatidi (370 aa) initn: 541 init1: 224 opt: 578 Z-score: 649.7 bits: 128.8 E(85289): 1.9e-29 Smith-Waterman score: 578; 30.6% identity (64.8% similar) in 330 aa overlap (38-355:46-368) 10 20 30 40 50 60 pF1KB8 NFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTT ::.:::.::. : ..: :. : . :. XP_006 SSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSVSLFVFCFRMKMRSETA 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB8 LYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSI .. :::..::.::. .:: .: .: .. : .::.::.:.. .: : :... :.::.:. XP_006 IFITNLAVSDLLFVCTLPFKI-FYNFNRHWPFGDTLCKISGTAFLTNIYGSMLFLTCISV 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB8 DRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNF :::.:.:.:.: :. ... :: :::::.. . . .. . ::.: . XP_006 DRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSK 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB8 EETKS-LPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTI . :. : : . .:...:::. . : : . .:: .. . :.::: . . XP_006 RVWKTYLSKITIFIEVVGFIIPLILNVSCSSVV----LRTLRKPATLSQIGTNKKKVLKM 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB8 ILI-IVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDP : . ..:::.::.::. ... . . .: . . .: .. .: .:.:: ..:::.:: XP_006 ITVHMAVFVVCFVPYNSVLFLYAL--VRSQAITNCFLERFAKIMYPITLCLATLNCCFDP 260 270 280 290 300 310 320 330 340 350 pF1KB8 FIYFFACKGYKRKV-----MRM---LKRQVSVSISSAVKSAPEENSREMTET--QMMIHS :::.:. ...... .:: .: .. .. . .. . :: : . :.. ..:..: XP_006 FIYYFTLESFQKSFYINAHIRMESLFKTETPLTTKPSLPAIQEEVSDQTTNNGGELMLES 310 320 330 340 350 360 360 pF1KB8 KSSNGK XP_006 TF 370 361 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:47:59 2016 done: Fri Nov 4 15:48:00 2016 Total Scan time: 6.970 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]