FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8811, 362 aa 1>>>pF1KB8811 362 - 362 aa - 362 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9997+/-0.000967; mu= 12.2924+/- 0.057 mean_var=140.6290+/-43.569, 0's: 0 Z-trim(106.1): 248 B-trim: 1195 in 2/47 Lambda= 0.108153 statistics sampled from 8360 (8785) to 8360 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.27), width: 16 Scan time: 2.180 The best scores are: opt bits E(32554) CCDS12669.1 GPR4 gene_id:2828|Hs108|chr19 ( 362) 2479 399.1 3.1e-111 CCDS9894.2 GPR68 gene_id:8111|Hs108|chr14 ( 365) 1112 185.8 5e-47 CCDS9879.1 GPR65 gene_id:8477|Hs108|chr14 ( 337) 798 136.8 2.7e-32 CCDS61567.1 GPR132 gene_id:29933|Hs108|chr14 ( 371) 667 116.4 4.1e-26 CCDS9997.1 GPR132 gene_id:29933|Hs108|chr14 ( 380) 667 116.4 4.1e-26 CCDS2516.1 ACKR3 gene_id:57007|Hs108|chr2 ( 362) 540 96.5 3.7e-20 CCDS318.1 PTAFR gene_id:5724|Hs108|chr1 ( 342) 529 94.8 1.2e-19 CCDS9410.1 LPAR6 gene_id:10161|Hs108|chr13 ( 344) 525 94.2 1.8e-19 CCDS14441.1 LPAR4 gene_id:2846|Hs108|chrX ( 370) 517 93.0 4.5e-19 CCDS2148.1 GPR17 gene_id:2840|Hs108|chr2 ( 367) 507 91.4 1.3e-18 CCDS4033.1 F2RL1 gene_id:2150|Hs108|chr5 ( 397) 506 91.3 1.5e-18 CCDS3169.1 P2RY1 gene_id:5028|Hs108|chr3 ( 373) 500 90.3 2.8e-18 CCDS9492.1 GPR183 gene_id:1880|Hs108|chr13 ( 361) 484 87.8 1.6e-17 CCDS2737.1 CCR1 gene_id:1230|Hs108|chr3 ( 355) 475 86.4 4.1e-17 CCDS2656.1 CCR4 gene_id:1233|Hs108|chr3 ( 360) 471 85.8 6.4e-17 CCDS8219.1 P2RY2 gene_id:5029|Hs108|chr11 ( 377) 460 84.1 2.2e-16 CCDS8553.1 LPAR5 gene_id:57121|Hs108|chr12 ( 372) 459 83.9 2.4e-16 CCDS9482.1 OXGR1 gene_id:27199|Hs108|chr13 ( 337) 458 83.7 2.5e-16 CCDS2738.1 CCR3 gene_id:1232|Hs108|chr3 ( 355) 457 83.6 2.9e-16 CCDS54574.1 CCR3 gene_id:1232|Hs108|chr3 ( 376) 457 83.6 3e-16 CCDS14398.1 P2RY4 gene_id:5030|Hs108|chrX ( 365) 447 82.0 8.7e-16 CCDS14569.1 AGTR2 gene_id:186|Hs108|chrX ( 363) 444 81.6 1.2e-15 CCDS9412.1 CYSLTR2 gene_id:57105|Hs108|chr13 ( 346) 443 81.4 1.3e-15 CCDS58959.1 F2RL2 gene_id:2151|Hs108|chr5 ( 352) 435 80.1 3.1e-15 CCDS4031.1 F2RL2 gene_id:2151|Hs108|chr5 ( 374) 435 80.2 3.2e-15 CCDS14443.1 GPR174 gene_id:84636|Hs108|chrX ( 333) 434 80.0 3.3e-15 CCDS3137.1 AGTR1 gene_id:185|Hs108|chr3 ( 359) 429 79.2 6e-15 CCDS82855.1 AGTR1 gene_id:185|Hs108|chr3 ( 388) 429 79.3 6.3e-15 CCDS82854.1 AGTR1 gene_id:185|Hs108|chr3 ( 394) 429 79.3 6.4e-15 CCDS8220.1 P2RY6 gene_id:5031|Hs108|chr11 ( 328) 427 78.9 7e-15 CCDS4032.1 F2R gene_id:2149|Hs108|chr5 ( 425) 425 78.7 1e-14 CCDS14439.1 CYSLTR1 gene_id:10800|Hs108|chrX ( 337) 423 78.3 1.1e-14 CCDS12350.1 F2RL3 gene_id:9002|Hs108|chr19 ( 385) 420 77.9 1.7e-14 CCDS8927.1 GPR182 gene_id:11318|Hs108|chr12 ( 404) 414 76.9 3.3e-14 CCDS14115.1 P2RY8 gene_id:286530|Hs108|chrX ( 359) 411 76.4 4.2e-14 CCDS14115.1 P2RY8 gene_id:286530|Hs108|chrY ( 359) 411 76.4 4.2e-14 CCDS14258.1 GPR34 gene_id:2857|Hs108|chrX ( 381) 411 76.4 4.4e-14 CCDS7950.1 APLNR gene_id:187|Hs108|chr11 ( 380) 405 75.5 8.3e-14 CCDS14416.1 CXCR3 gene_id:2833|Hs108|chrX ( 368) 403 75.2 1e-13 CCDS48135.1 CXCR3 gene_id:2833|Hs108|chrX ( 415) 403 75.2 1.1e-13 CCDS2706.1 ACKR2 gene_id:1238|Hs108|chr3 ( 384) 401 74.9 1.3e-13 CCDS2739.1 CCR5 gene_id:1234|Hs108|chr3 ( 352) 399 74.5 1.5e-13 CCDS46813.1 CCR2 gene_id:729230|Hs108|chr3 ( 360) 399 74.5 1.5e-13 CCDS43078.1 CCR2 gene_id:729230|Hs108|chr3 ( 374) 399 74.6 1.6e-13 CCDS14442.1 P2RY10 gene_id:27334|Hs108|chrX ( 339) 398 74.4 1.7e-13 CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 ( 372) 397 74.2 2e-13 CCDS43069.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 355) 394 73.8 2.6e-13 CCDS54571.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 387) 394 73.8 2.8e-13 CCDS55069.1 OPRM1 gene_id:4988|Hs108|chr6 ( 389) 392 73.5 3.5e-13 CCDS47508.1 OPRM1 gene_id:4988|Hs108|chr6 ( 392) 392 73.5 3.5e-13 >>CCDS12669.1 GPR4 gene_id:2828|Hs108|chr19 (362 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 2110.5 bits: 399.1 E(32554): 3.1e-111 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP 310 320 330 340 350 360 pF1KB8 AQ :: CCDS12 AQ >>CCDS9894.2 GPR68 gene_id:8111|Hs108|chr14 (365 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 957.7 bits: 185.8 E(32554): 5e-47 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:1-331) 10 20 30 40 50 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :.. :::::::: CCDS98 MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::..:::::::::: CCDS98 CNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG ::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: :::..:... CCDS98 LAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 WVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVC : .: :: .:::::: :.: ::.::::::: : .:....: .:.::.:: ..: :.: CCDS98 WQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 FAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGAR : ::::::: ::. :. : : . ::.::: :: .::.::::::.:::.:.: .. CCDS98 FLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTH 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQ :.:. : ::. .. . : . : .: .: .. CCDS98 RDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNS 300 310 320 330 340 350 360 pF1KB8 LKMLPPAQ CCDS98 PGSGGFPTGRLA 360 >>CCDS9879.1 GPR65 gene_id:8477|Hs108|chr14 (337 aa) initn: 719 init1: 453 opt: 798 Z-score: 693.3 bits: 136.8 E(32554): 2.7e-32 Smith-Waterman score: 799; 41.4% identity (70.5% similar) in 302 aa overlap (15-307:12-307) 10 20 30 40 50 60 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS .:: . : .::::: :..:.: .: ... :.....:::.::..:: CCDS98 MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLS 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA ..:::: :::::.:: ..::: .:. :: .:..: :.: : ::: ::.:::::::. CCDS98 LSDLLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVV 60 70 80 90 100 110 130 140 150 160 170 pF1KB8 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELF-----RDRYNHTFCFEKFPME .::.: :: . :. :: .: : :.. :..:: .. : :.:..:.:.: CCDS98 YPLKFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 GWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLV : .::.:. .:. .: . .:. : . .::: . .:: .:: .: .: .:. . .. CCDS98 KWQINLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 CFAPYHVLLLSRS----AIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNE ::.:.::.:: : :. . . : .:... :. ..:.:::::::::::::.:.: CCDS98 CFTPFHVMLLIRCILEHAVNFEDHSNSG--KRTYTMYRITVALTSLNCVADPILYCFVTE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 GARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGD .: : . :.:.: CCDS98 TGRYD----MWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE 300 310 320 330 >>CCDS61567.1 GPR132 gene_id:29933|Hs108|chr14 (371 aa) initn: 677 init1: 343 opt: 667 Z-score: 582.4 bits: 116.4 E(32554): 4.1e-26 Smith-Waterman score: 667; 38.8% identity (68.3% similar) in 281 aa overlap (23-299:39-312) 10 20 30 40 50 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNEL .: : .:.:.:::. : : :: : : : CCDS61 TTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCIS .:::. :.. .::: :::::: :. .. : : .::. ..::. :::.:: :::::: CCDS61 AVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCIS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 VDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKF ::..::.. :. :: .::. .:. .. .: :.:. : :. . ::. . CCDS61 CDRFVAVVYALESRGRRRRRTAILISACIFIL-VGIVHYPVFQTE---DKET---CFDML 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 PMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAI :.. .: . : ::: .: ... .. . :.:... :.. .:::.:. :.....: CCDS61 QMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVI 190 200 210 220 230 240 240 250 260 270 280 pF1KB8 VLVCFAPYHVLLLSRSAI---YLG-RPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCL ::::::::..:: ..: : : : ::.:::...: : ....: :::::.: : CCDS61 FLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 VNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPS ... .:..:.. CCDS61 ATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFSRPVHPPGSPC 310 320 330 340 350 360 >>CCDS9997.1 GPR132 gene_id:29933|Hs108|chr14 (380 aa) initn: 677 init1: 343 opt: 667 Z-score: 582.2 bits: 116.4 E(32554): 4.1e-26 Smith-Waterman score: 667; 38.8% identity (68.3% similar) in 281 aa overlap (23-299:48-321) 10 20 30 40 50 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNEL .: : .:.:.:::. : : :: : : : CCDS99 TTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVL 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB8 GVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCIS .:::. :.. .::: :::::: :. .. : : .::. ..::. :::.:: :::::: CCDS99 AVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCIS 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB8 VDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKF ::..::.. :. :: .::. .:. .. .: :.:. : :. . ::. . CCDS99 CDRFVAVVYALESRGRRRRRTAILISACIFIL-VGIVHYPVFQTE---DKET---CFDML 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB8 PMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAI :.. .: . : ::: .: ... .. . :.:... :.. .:::.:. :.....: CCDS99 QMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVI 200 210 220 230 240 250 240 250 260 270 280 pF1KB8 VLVCFAPYHVLLLSRSAI---YLG-RPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCL ::::::::..:: ..: : : : ::.:::...: : ....: :::::.: : CCDS99 FLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVL 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB8 VNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPS ... .:..:.. CCDS99 ATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFSRPVHPPGSPC 320 330 340 350 360 370 >>CCDS2516.1 ACKR3 gene_id:57007|Hs108|chr2 (362 aa) initn: 357 init1: 279 opt: 540 Z-score: 475.4 bits: 96.5 E(32554): 3.7e-20 Smith-Waterman score: 540; 28.7% identity (62.5% similar) in 317 aa overlap (23-334:50-361) 10 20 30 40 50 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNEL .:::.. .:. .: ...:. . . CCDS25 PCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDT 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB8 GVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCIS :..::.:::: . :.:.:: ...:..: : .::. .:: :.. :: :: :.: CCDS25 HCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMS 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB8 VDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNH-TFCFEK :::::.... :. . .: .:: . .. .. . . :. :.: CCDS25 VDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSASNNETYCRSF 140 150 160 170 180 190 180 190 200 210 220 pF1KB8 FP---MEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALS .: .. :. :.: : .:: :.... . : . ::. :.:.. ::: . ... .: CCDS25 YPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAI--SASSD-QEKHSSRKIIFS 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB8 LIAIVLVCFAPYHV-LLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYC ... :::. :::: .::. .: :. : .:. .:.: : . .. ..: ..:.:: CCDS25 YVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCCVNPVLYS 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB8 LVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPP ..:.. : .. ::. .... :. .. .:: . :: .. ..:: CCDS25 FINRNYRYELMKAF--IFKYSAKTGLTKLIDASRVSETEYSALEQSTK 320 330 340 350 360 350 360 pF1KB8 SQGDQVQLKMLPPAQ >>CCDS318.1 PTAFR gene_id:5724|Hs108|chr1 (342 aa) initn: 431 init1: 310 opt: 529 Z-score: 466.4 bits: 94.8 E(32554): 1.2e-19 Smith-Waterman score: 529; 28.9% identity (65.0% similar) in 311 aa overlap (7-304:5-311) 10 20 30 40 50 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYR--QVQQRNELGVYLMN .. :.::. . . : .: ... .:. .: .::. : .. ::. ....: CCDS31 MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLA :..::.:.. :::::. :. .. ::: :.. : .:. : : :.::: :. .:. : CCDS31 LTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHD--ELFRDRY---NHTFCFEKFP :..:.. :. : ....: :.:.. .:: : :. : . : : : :::.. CCDS31 VTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYE 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 MEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSV--STERQEKAKIKRLAL---- .: : . . ..:. : : ..... . ... .: . ...:..:..:: :: CCDS31 -KGSVPVL-IIHIFIVFSFFLVFLIILFCNLV-IIRTLLMQPVQQQRNAEVKRRALWMVC 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 SLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYC ...:. ..::.:.::. : . :: : :.. . .:.. .: . : ::: ::..:: CCDS31 TVLAVFIICFVPHHVVQLPWTLAELGFQ-DSKFHQAINDAHQVTLCLLSTNCVLDPVIYC 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPP .... :. ... .... CCDS31 FLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN 300 310 320 330 340 >>CCDS9410.1 LPAR6 gene_id:10161|Hs108|chr13 (344 aa) initn: 451 init1: 213 opt: 525 Z-score: 463.0 bits: 94.2 E(32554): 1.8e-19 Smith-Waterman score: 525; 29.8% identity (60.0% similar) in 295 aa overlap (9-297:9-302) 10 20 30 40 50 60 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS : .. . . .. .:. .:: .::.:.. .. ::: .:..::. CCDS94 MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA ..:::.. :::. . :: . :: : ::. ..::::.: :: :: ::::::.::.. CCDS94 MSDLLFVFTLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIV 70 80 90 100 110 130 140 150 160 170 pF1KB8 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTF-CFEKFPMEGWVA .:.. :: ..: : . :: : .:... .: . . : . :::.:: : . CCDS94 YPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 WMNLYRVF---VGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVC ... .: :::..: : . .:... :. :.. : : : . .. ... : CCDS94 YLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 F--APYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGAR : .::.. :. : . .:. : . : .: .. :: :::.: .... . CCDS94 FCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQ ... CCDS94 NSIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIFDNESAA 300 310 320 330 340 >>CCDS14441.1 LPAR4 gene_id:2846|Hs108|chrX (370 aa) initn: 433 init1: 172 opt: 517 Z-score: 455.9 bits: 93.0 E(32554): 4.5e-19 Smith-Waterman score: 517; 30.0% identity (58.8% similar) in 337 aa overlap (1-330:22-343) 10 20 30 pF1KB8 MGNHTWEG-CHVDSRVDHLFPPSLYIFVIGVGLPTNCLA .:: : .. : ::. . . ..: :. .:: :: .. CCDS14 MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSVS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 LWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFY :.. ....:.: .... ::...:::..::::. . .. . .: : ::. : : CCDS14 LFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKI-FYNFNRHWPFGDTLCKISGTAFL 70 80 90 100 110 100 110 120 130 140 150 pF1KB8 TNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATEL-GANSAPLFHDE :::: :. :: ::::::.::...:.: .: .... : . :: : :. :: :: CCDS14 TNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTT 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB8 LFRDRYNHTFCFEKFPMEGWVAWMNLYRVF---VGFLFPWALMLLSYRGILRAVR--GSV . : ::: : . : .... .: :::..: : . .::..: ... CCDS14 NVNN--ATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 STERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSL : .: :. .. .:. .:::.::. .:. . . .: .:. . : .: CCDS14 SQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPITL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 AFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRN ...::: ::..: .. :. ... : .. : . :::::.: CCDS14 CLATLNCCFDPFIYYFTLESFQKSFYINAHIRMESL------------FKTETPLTTKPS 300 310 320 330 340 340 350 360 pF1KB8 STAKAMTGSWAATPPSQGDQVQLKMLPPAQ CCDS14 LPAIQEEVSDQTTNNGGELMLESTF 350 360 370 >>CCDS2148.1 GPR17 gene_id:2840|Hs108|chr2 (367 aa) initn: 430 init1: 297 opt: 507 Z-score: 447.5 bits: 91.4 E(32554): 1.3e-18 Smith-Waterman score: 507; 33.1% identity (62.3% similar) in 305 aa overlap (5-305:47-340) 10 20 30 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPT : : : .. ..... :.:.. . ..: CCDS21 MLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVG 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 NCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFG : :::: :. .. . .:.::.:..::: . .:: . : . ..: : .:.: : CCDS21 NTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTG 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 FIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLF :.:: :.: :: :: :::.::.::..::.. .::: : . . .:.. ... :::. CCDS21 FLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVV-VAVAMAPLL 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB8 HDELFRDRYNHTF-CFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVS . . ::: :.. . .. . : . :.: ::. . : :.:..: .. CCDS21 VSPQTV-QTNHTVVCLQLYREKA--SHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLR 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB8 TERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAI---YLGRPWDCGFEERVFSAYHS .:.. :.: :. ..:: ::::.:::: .::. : .. .:. .. . : . CCDS21 VEKRLKTKAVRMIAIVLAIFLVCFVPYHV---NRSVYVLHYRSHGASCATQRILALANRI 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 SLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSK . .:::: . :::.: .: : : .:: ::: CCDS21 TSCLTSLNGALDPIMYFFVAEKFR----HALCNLLCGKRLKGPPPSFEGKTNESSLSAKS 310 320 330 340 350 360 340 350 360 pF1KB8 RNSTAKAMTGSWAATPPSQGDQVQLKMLPPAQ CCDS21 EL 362 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:48:34 2016 done: Fri Nov 4 15:48:35 2016 Total Scan time: 2.180 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]