FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8811, 362 aa 1>>>pF1KB8811 362 - 362 aa - 362 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4200+/-0.000417; mu= 15.9294+/- 0.026 mean_var=158.0921+/-43.365, 0's: 0 Z-trim(111.6): 552 B-trim: 0 in 0/53 Lambda= 0.102004 statistics sampled from 19520 (20259) to 19520 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.238), width: 16 Scan time: 6.940 The best scores are: opt bits E(85289) NP_005273 (OMIM: 600551) G-protein coupled recepto ( 362) 2479 377.7 2.3e-104 XP_016882097 (OMIM: 600551) PREDICTED: G-protein c ( 362) 2479 377.7 2.3e-104 XP_016882096 (OMIM: 600551) PREDICTED: G-protein c ( 362) 2479 377.7 2.3e-104 NP_003476 (OMIM: 601404) ovarian cancer G-protein ( 365) 1112 176.5 8.3e-44 NP_001171147 (OMIM: 601404) ovarian cancer G-prote ( 365) 1112 176.5 8.3e-44 XP_005268167 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_011535499 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_011535498 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_006720325 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_011535501 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_005268168 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_005268169 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 XP_011535500 (OMIM: 601404) PREDICTED: ovarian can ( 375) 1112 176.5 8.4e-44 NP_003599 (OMIM: 604620) psychosine receptor [Homo ( 337) 798 130.3 6.4e-30 NP_001265624 (OMIM: 606167) probable G-protein cou ( 371) 667 111.0 4.3e-24 NP_001265623 (OMIM: 606167) probable G-protein cou ( 380) 667 111.1 4.4e-24 NP_037477 (OMIM: 606167) probable G-protein couple ( 380) 667 111.1 4.4e-24 XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 540 92.3 1.8e-18 NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 540 92.3 1.8e-18 XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 540 92.3 1.8e-18 XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 540 92.3 1.8e-18 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 529 90.7 5.3e-18 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 529 90.7 5.3e-18 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 529 90.7 5.3e-18 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 529 90.7 5.3e-18 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 525 90.1 8.1e-18 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 525 90.1 8.1e-18 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 525 90.1 8.1e-18 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 517 89.0 1.9e-17 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 517 89.0 1.9e-17 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 517 89.0 1.9e-17 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 517 89.0 1.9e-17 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 517 89.0 1.9e-17 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 517 89.0 1.9e-17 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 507 87.4 5e-17 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 507 87.4 5e-17 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 507 87.5 5.2e-17 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 507 87.5 5.2e-17 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 507 87.5 5.2e-17 XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 506 87.4 5.9e-17 NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 506 87.4 6.1e-17 NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 500 86.5 1.1e-16 XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 484 84.1 5.4e-16 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 484 84.1 5.4e-16 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 475 82.8 1.3e-15 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 471 82.2 2e-15 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 471 82.2 2e-15 NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 464 81.2 4.3e-15 NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 464 81.2 4.3e-15 NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 464 81.2 4.3e-15 >>NP_005273 (OMIM: 600551) G-protein coupled receptor 4 (362 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 1994.8 bits: 377.7 E(85289): 2.3e-104 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP 310 320 330 340 350 360 pF1KB8 AQ :: NP_005 AQ >>XP_016882097 (OMIM: 600551) PREDICTED: G-protein coupl (362 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 1994.8 bits: 377.7 E(85289): 2.3e-104 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP 310 320 330 340 350 360 pF1KB8 AQ :: XP_016 AQ >>XP_016882096 (OMIM: 600551) PREDICTED: G-protein coupl (362 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 1994.8 bits: 377.7 E(85289): 2.3e-104 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB8 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP 310 320 330 340 350 360 pF1KB8 AQ :: XP_016 AQ >>NP_003476 (OMIM: 601404) ovarian cancer G-protein coup (365 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.5 bits: 176.5 E(85289): 8.3e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:1-331) 10 20 30 40 50 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :.. :::::::: NP_003 MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::..:::::::::: NP_003 CNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG ::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: :::..:... NP_003 LAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 WVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVC : .: :: .:::::: :.: ::.::::::: : .:....: .:.::.:: ..: :.: NP_003 WQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 FAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGAR : ::::::: ::. :. : : . ::.::: :: .::.::::::.:::.:.: .. NP_003 FLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTH 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQ :.:. : ::. .. . : . : .: .: .. NP_003 RDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNS 300 310 320 330 340 350 360 pF1KB8 LKMLPPAQ NP_003 PGSGGFPTGRLA 360 >>NP_001171147 (OMIM: 601404) ovarian cancer G-protein c (365 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.5 bits: 176.5 E(85289): 8.3e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:1-331) 10 20 30 40 50 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :.. :::::::: NP_001 MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::..:::::::::: NP_001 CNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG ::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: :::..:... NP_001 LAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 WVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVC : .: :: .:::::: :.: ::.::::::: : .:....: .:.::.:: ..: :.: NP_001 WQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 FAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGAR : ::::::: ::. :. : : . ::.::: :: .::.::::::.:::.:.: .. NP_001 FLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTH 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQ :.:. : ::. .. . : . : .: .: .. NP_001 RDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNS 300 310 320 330 340 350 360 pF1KB8 LKMLPPAQ NP_001 PGSGGFPTGRLA 360 >>XP_005268167 (OMIM: 601404) PREDICTED: ovarian cancer (375 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.4 bits: 176.5 E(85289): 8.4e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:11-341) 10 20 30 40 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQV ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :. XP_005 MRSVAPSGPKMGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 QQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIA . :::::::: ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::.. XP_005 KARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 FLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT ::::::::::::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: XP_005 FLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 FCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLA :::..:...: .: :: .:::::: :.: ::.::::::: : .:....: .:.::. XP_005 VCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPI :: ..: :.:: ::::::: ::. :. : : . ::.::: :: .::.::::::. XP_005 LSTVVIFLACFLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPV 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAA :::.:.: .. :.:. : ::. .. . : . : .: .: .. XP_005 LYCFVSETTHRDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTK 300 310 320 330 340 350 350 360 pF1KB8 TPPSQGDQVQLKMLPPAQ XP_005 LHPAFQTPNSPGSGGFPTGRLA 360 370 >>XP_011535499 (OMIM: 601404) PREDICTED: ovarian cancer (375 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.4 bits: 176.5 E(85289): 8.4e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:11-341) 10 20 30 40 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQV ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :. XP_011 MRSVAPSGPKMGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 QQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIA . :::::::: ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::.. XP_011 KARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 FLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT ::::::::::::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: XP_011 FLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 FCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLA :::..:...: .: :: .:::::: :.: ::.::::::: : .:....: .:.::. XP_011 VCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPI :: ..: :.:: ::::::: ::. :. : : . ::.::: :: .::.::::::. XP_011 LSTVVIFLACFLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPV 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAA :::.:.: .. :.:. : ::. .. . : . : .: .: .. XP_011 LYCFVSETTHRDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTK 300 310 320 330 340 350 350 360 pF1KB8 TPPSQGDQVQLKMLPPAQ XP_011 LHPAFQTPNSPGSGGFPTGRLA 360 370 >>XP_011535498 (OMIM: 601404) PREDICTED: ovarian cancer (375 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.4 bits: 176.5 E(85289): 8.4e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:11-341) 10 20 30 40 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQV ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :. XP_011 MRSVAPSGPKMGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 QQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIA . :::::::: ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::.. XP_011 KARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 FLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT ::::::::::::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: XP_011 FLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 FCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLA :::..:...: .: :: .:::::: :.: ::.::::::: : .:....: .:.::. XP_011 VCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPI :: ..: :.:: ::::::: ::. :. : : . ::.::: :: .::.::::::. XP_011 LSTVVIFLACFLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPV 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAA :::.:.: .. :.:. : ::. .. . : . : .: .: .. XP_011 LYCFVSETTHRDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTK 300 310 320 330 340 350 350 360 pF1KB8 TPPSQGDQVQLKMLPPAQ XP_011 LHPAFQTPNSPGSGGFPTGRLA 360 370 >>XP_006720325 (OMIM: 601404) PREDICTED: ovarian cancer (375 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.4 bits: 176.5 E(85289): 8.4e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:11-341) 10 20 30 40 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQV ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :. XP_006 MRSVAPSGPKMGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 QQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIA . :::::::: ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::.. XP_006 KARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 FLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT ::::::::::::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: XP_006 FLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 FCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLA :::..:...: .: :: .:::::: :.: ::.::::::: : .:....: .:.::. XP_006 VCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPI :: ..: :.:: ::::::: ::. :. : : . ::.::: :: .::.::::::. XP_006 LSTVVIFLACFLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPV 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAA :::.:.: .. :.:. : ::. .. . : . : .: .: .. XP_006 LYCFVSETTHRDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTK 300 310 320 330 340 350 350 360 pF1KB8 TPPSQGDQVQLKMLPPAQ XP_006 LHPAFQTPNSPGSGGFPTGRLA 360 370 >>XP_011535501 (OMIM: 601404) PREDICTED: ovarian cancer (375 aa) initn: 1093 init1: 940 opt: 1112 Z-score: 907.4 bits: 176.5 E(85289): 8.4e-44 Smith-Waterman score: 1112; 49.1% identity (75.4% similar) in 338 aa overlap (1-332:11-341) 10 20 30 40 pF1KB8 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQV ::: : .. : .: . . . : .:. :. ::.:.:::.:. .: :. XP_011 MRSVAPSGPKMGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 QQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIA . :::::::: ::..:::.:::.::.:..: :.:::: :: ::.. :...: :::::.. XP_011 KARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 FLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT ::::::::::::::::.:: ..: .:.::.:: :.:: :: .. :.:.:...:. .: XP_011 FLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 FCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLA :::..:...: .: :: .:::::: :.: ::.::::::: : .:....: .:.::. XP_011 VCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 LSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPI :: ..: :.:: ::::::: ::. :. : : . ::.::: :: .::.::::::. XP_011 LSTVVIFLACFLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPV 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAA :::.:.: .. :.:. : ::. .. . : . : .: .: .. XP_011 LYCFVSETTHRDLARLRGACLAFLTCSRTGR-AREAYPLGAPEASGKSGAQGEEPELLTK 300 310 320 330 340 350 350 360 pF1KB8 TPPSQGDQVQLKMLPPAQ XP_011 LHPAFQTPNSPGSGGFPTGRLA 360 370 362 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:48:35 2016 done: Fri Nov 4 15:48:36 2016 Total Scan time: 6.940 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]