FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8818, 381 aa 1>>>pF1KB8818 381 - 381 aa - 381 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1640+/-0.000521; mu= 17.5630+/- 0.033 mean_var=98.6739+/-23.728, 0's: 0 Z-trim(109.4): 667 B-trim: 1841 in 2/48 Lambda= 0.129114 statistics sampled from 16757 (17536) to 16757 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.206), width: 16 Scan time: 7.720 The best scores are: opt bits E(85289) NP_001091048 (OMIM: 300241) probable G-protein cou ( 381) 2496 476.2 5.5e-134 NP_005291 (OMIM: 300241) probable G-protein couple ( 381) 2496 476.2 5.5e-134 XP_005272654 (OMIM: 300241) PREDICTED: probable G- ( 381) 2496 476.2 5.5e-134 XP_011511642 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 645 131.4 3.1e-30 XP_005247979 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 645 131.4 3.1e-30 NP_055694 (OMIM: 610116) P2Y purinoceptor 14 [Homo ( 338) 645 131.4 3.1e-30 XP_016863072 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 645 131.4 3.1e-30 NP_001074924 (OMIM: 610116) P2Y purinoceptor 14 [H ( 338) 645 131.4 3.1e-30 XP_005247980 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 645 131.4 3.1e-30 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 577 118.7 2e-26 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 577 118.7 2e-26 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 577 118.7 2.2e-26 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 577 118.7 2.2e-26 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 577 118.7 2.2e-26 NP_073625 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 575 118.3 2.7e-26 NP_795345 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 575 118.3 2.7e-26 XP_016862558 (OMIM: 600515,609821) PREDICTED: P2Y ( 342) 575 118.3 2.7e-26 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 541 112.0 2.2e-24 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 541 112.0 2.2e-24 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 541 112.0 2.2e-24 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 540 111.8 2.6e-24 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 540 111.8 2.6e-24 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 540 111.8 2.6e-24 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 540 111.8 2.6e-24 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 540 111.8 2.6e-24 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 540 111.8 2.6e-24 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 539 111.6 2.8e-24 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 539 111.6 2.8e-24 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 539 111.6 2.8e-24 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 539 111.6 2.8e-24 NP_795713 (OMIM: 606380) P2Y purinoceptor 13 [Homo ( 354) 534 110.7 5.4e-24 XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 524 108.9 2e-23 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 524 108.9 2e-23 NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 518 107.7 4.2e-23 NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 518 107.7 4.2e-23 NP_076404 (OMIM: 606379) G-protein coupled recepto ( 358) 505 105.3 2.3e-22 NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 502 104.7 3.3e-22 NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 502 104.7 3.3e-22 NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 502 104.7 3.3e-22 NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 502 104.7 3.3e-22 NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 481 100.9 5.2e-21 NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 462 97.3 6.2e-20 NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 462 97.3 6.2e-20 NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 462 97.3 6.2e-20 >>NP_001091048 (OMIM: 300241) probable G-protein coupled (381 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 2526.5 bits: 476.2 E(85289): 5.5e-134 Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFK 310 320 330 340 350 360 370 380 pF1KB8 PGYSLHDTSVAVKIQSSSKST ::::::::::::::::::::: NP_001 PGYSLHDTSVAVKIQSSSKST 370 380 >>NP_005291 (OMIM: 300241) probable G-protein coupled re (381 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 2526.5 bits: 476.2 E(85289): 5.5e-134 Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 WKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFK 310 320 330 340 350 360 370 380 pF1KB8 PGYSLHDTSVAVKIQSSSKST ::::::::::::::::::::: NP_005 PGYSLHDTSVAVKIQSSSKST 370 380 >>XP_005272654 (OMIM: 300241) PREDICTED: probable G-prot (381 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 2526.5 bits: 476.2 E(85289): 5.5e-134 Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFK 310 320 330 340 350 360 370 380 pF1KB8 PGYSLHDTSVAVKIQSSSKST ::::::::::::::::::::: XP_005 PGYSLHDTSVAVKIQSSSKST 370 380 >>XP_011511642 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 555 init1: 345 opt: 645 Z-score: 663.7 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 647; 33.2% identity (67.7% similar) in 319 aa overlap (26-342:2-310) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :.. : :::.. .: .. . . .. . XP_011 MINSTSTQPPDE--------SCSQNLLITQQIIPVL 10 20 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW : ..::.:.. : .. ..:. . ... : ::: :..:::... . .::.:. . . : XP_011 YCMVFIAGILLNGVSGWIFFYVPSSKSFI-IYLKNIVIADFVMSLTFPFKILGDSGLGPW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :.:..:.: ..:::.:::.::...:.::.::: :: . . ... : . :::: XP_011 QLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWM 90 100 110 120 130 140 190 200 210 220 230 pF1KB8 LALGGFLTMIILTLKKGGHNSTM-CFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYI : : . :::: .. . . . :.. ... . : . :.:.:..::..:::.:. : XP_011 LMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 KIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVS-S : :.... . :. .: : ..:: : ....: .:::::: :. : .:: .. : XP_011 AITKKIFKSHLKSSRNSTSVK-KKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 CYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSE : :::.. .:. :.::. : ::::..::.. . .:.:.:. : XP_011 CQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIK 270 280 290 300 310 320 360 370 380 pF1KB8 FKPGYSLHDTSVAVKIQSSSKST XP_011 RGNTTLESTDTL 330 >>XP_005247979 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 555 init1: 345 opt: 645 Z-score: 663.7 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 647; 33.2% identity (67.7% similar) in 319 aa overlap (26-342:2-310) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :.. : :::.. .: .. . . .. . XP_005 MINSTSTQPPDE--------SCSQNLLITQQIIPVL 10 20 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW : ..::.:.. : .. ..:. . ... : ::: :..:::... . .::.:. . . : XP_005 YCMVFIAGILLNGVSGWIFFYVPSSKSFI-IYLKNIVIADFVMSLTFPFKILGDSGLGPW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :.:..:.: ..:::.:::.::...:.::.::: :: . . ... : . :::: XP_005 QLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWM 90 100 110 120 130 140 190 200 210 220 230 pF1KB8 LALGGFLTMIILTLKKGGHNSTM-CFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYI : : . :::: .. . . . :.. ... . : . :.:.:..::..:::.:. : XP_005 LMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 KIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVS-S : :.... . :. .: : ..:: : ....: .:::::: :. : .:: .. : XP_005 AITKKIFKSHLKSSRNSTSVK-KKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 CYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSE : :::.. .:. :.::. : ::::..::.. . .:.:.:. : XP_005 CQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIK 270 280 290 300 310 320 360 370 380 pF1KB8 FKPGYSLHDTSVAVKIQSSSKST XP_005 RGNTTLESTDTL 330 >>NP_055694 (OMIM: 610116) P2Y purinoceptor 14 [Homo sap (338 aa) initn: 555 init1: 345 opt: 645 Z-score: 663.7 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 647; 33.2% identity (67.7% similar) in 319 aa overlap (26-342:2-310) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :.. : :::.. .: .. . . .. . NP_055 MINSTSTQPPDE--------SCSQNLLITQQIIPVL 10 20 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW : ..::.:.. : .. ..:. . ... : ::: :..:::... . .::.:. . . : NP_055 YCMVFIAGILLNGVSGWIFFYVPSSKSFI-IYLKNIVIADFVMSLTFPFKILGDSGLGPW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :.:..:.: ..:::.:::.::...:.::.::: :: . . ... : . :::: NP_055 QLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWM 90 100 110 120 130 140 190 200 210 220 230 pF1KB8 LALGGFLTMIILTLKKGGHNSTM-CFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYI : : . :::: .. . . . :.. ... . : . :.:.:..::..:::.:. : NP_055 LMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 KIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVS-S : :.... . :. .: : ..:: : ....: .:::::: :. : .:: .. : NP_055 AITKKIFKSHLKSSRNSTSVK-KKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 CYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSE : :::.. .:. :.::. : ::::..::.. . .:.:.:. : NP_055 CQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIK 270 280 290 300 310 320 360 370 380 pF1KB8 FKPGYSLHDTSVAVKIQSSSKST NP_055 RGNTTLESTDTL 330 >>XP_016863072 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 555 init1: 345 opt: 645 Z-score: 663.7 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 647; 33.2% identity (67.7% similar) in 319 aa overlap (26-342:2-310) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :.. : :::.. .: .. . . .. . XP_016 MINSTSTQPPDE--------SCSQNLLITQQIIPVL 10 20 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW : ..::.:.. : .. ..:. . ... : ::: :..:::... . .::.:. . . : XP_016 YCMVFIAGILLNGVSGWIFFYVPSSKSFI-IYLKNIVIADFVMSLTFPFKILGDSGLGPW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :.:..:.: ..:::.:::.::...:.::.::: :: . . ... : . :::: XP_016 QLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWM 90 100 110 120 130 140 190 200 210 220 230 pF1KB8 LALGGFLTMIILTLKKGGHNSTM-CFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYI : : . :::: .. . . . :.. ... . : . :.:.:..::..:::.:. : XP_016 LMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 KIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVS-S : :.... . :. .: : ..:: : ....: .:::::: :. : .:: .. : XP_016 AITKKIFKSHLKSSRNSTSVK-KKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 CYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSE : :::.. .:. :.::. : ::::..::.. . .:.:.:. : XP_016 CQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIK 270 280 290 300 310 320 360 370 380 pF1KB8 FKPGYSLHDTSVAVKIQSSSKST XP_016 RGNTTLESTDTL 330 >>NP_001074924 (OMIM: 610116) P2Y purinoceptor 14 [Homo (338 aa) initn: 555 init1: 345 opt: 645 Z-score: 663.7 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 647; 33.2% identity (67.7% similar) in 319 aa overlap (26-342:2-310) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :.. : :::.. .: .. . . .. . NP_001 MINSTSTQPPDE--------SCSQNLLITQQIIPVL 10 20 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW : ..::.:.. : .. ..:. . ... : ::: :..:::... . .::.:. . . : NP_001 YCMVFIAGILLNGVSGWIFFYVPSSKSFI-IYLKNIVIADFVMSLTFPFKILGDSGLGPW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :.:..:.: ..:::.:::.::...:.::.::: :: . . ... : . :::: NP_001 QLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWM 90 100 110 120 130 140 190 200 210 220 230 pF1KB8 LALGGFLTMIILTLKKGGHNSTM-CFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYI : : . :::: .. . . . :.. ... . : . :.:.:..::..:::.:. : NP_001 LMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 KIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVS-S : :.... . :. .: : ..:: : ....: .:::::: :. : .:: .. : NP_001 AITKKIFKSHLKSSRNSTSVK-KKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 CYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSE : :::.. .:. :.::. : ::::..::.. . .:.:.:. : NP_001 CQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIK 270 280 290 300 310 320 360 370 380 pF1KB8 FKPGYSLHDTSVAVKIQSSSKST NP_001 RGNTTLESTDTL 330 >>XP_005247980 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 555 init1: 345 opt: 645 Z-score: 663.7 bits: 131.4 E(85289): 3.1e-30 Smith-Waterman score: 647; 33.2% identity (67.7% similar) in 319 aa overlap (26-342:2-310) 10 20 30 40 50 60 pF1KB8 MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTS :.. : :::.. .: .. . . .. . XP_005 MINSTSTQPPDE--------SCSQNLLITQQIIPVL 10 20 70 80 90 100 110 120 pF1KB8 YSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKW : ..::.:.. : .. ..:. . ... : ::: :..:::... . .::.:. . . : XP_005 YCMVFIAGILLNGVSGWIFFYVPSSKSFI-IYLKNIVIADFVMSLTFPFKILGDSGLGPW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 TLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWM :.:..:.: ..:::.:::.::...:.::.::: :: . . ... : . :::: XP_005 QLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWM 90 100 110 120 130 140 190 200 210 220 230 pF1KB8 LALGGFLTMIILTLKKGGHNSTM-CFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYI : : . :::: .. . . . :.. ... . : . :.:.:..::..:::.:. : XP_005 LMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 KIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVS-S : :.... . :. .: : ..:: : ....: .:::::: :. : .:: .. : XP_005 AITKKIFKSHLKSSRNSTSVK-KKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 CYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSE : :::.. .:. :.::. : ::::..::.. . .:.:.:. : XP_005 CQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIK 270 280 290 300 310 320 360 370 380 pF1KB8 FKPGYSLHDTSVAVKIQSSSKST XP_005 RGNTTLESTDTL 330 >>NP_001154888 (OMIM: 603071) uracil nucleotide/cysteiny (339 aa) initn: 523 init1: 324 opt: 577 Z-score: 595.2 bits: 118.7 E(85289): 2e-26 Smith-Waterman score: 577; 31.4% identity (64.5% similar) in 338 aa overlap (33-357:8-328) 10 20 30 40 50 pF1KB8 SHTITMTTTSVSSWPYSSHRMRFITNHSDQPP---QNFSATPNVTTCPMDEKLLSTVLTT :: ::: .. : .. : . .... NP_001 MNGLEVAPPGLITNFS-LATAEQCGQETPLENMLFAS 10 20 30 60 70 80 90 100 110 pF1KB8 SYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNK : . ::..:::: .::..:. :.. . ...:...:.::: .. :: :..::.. :. NP_001 FYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNH 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB8 WTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYV---CC : .: : :...: :::.::: :: .: :: ::.. : .. :.. .. .:. : NP_001 WPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAI---VHPVKSLKLRRPLYAHLACA 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB8 IVWMLALGGFLTMIILTLKKGGHNSTMCFH-YRDKHNAKGEAIFNFILVVMFWLIFLLII ..:... .. ... .....:.. ::.: :. .:. . :.: : . :. . NP_001 FLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREK--ASHHALVS--LAVAFTFPFITTV 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 LSYIKIGKNL---LRISKR-RSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYI- :. : ..: ::. :: ..: ..: ::: :: .::::::. : .:. NP_001 TCYLLIIRSLRQGLRVEKRLKTK---------AVRMIAIVLAIFLVCFVPYHVNRSVYVL 210 220 230 240 250 260 300 310 320 330 340 pF1KB8 SSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLF-RRFQGE . . .:: ..:. .:.: :.:.:. :::.:::... ..:. .:.:: .:..: NP_001 HYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGP 270 280 290 300 310 320 350 360 370 380 pF1KB8 PSRSESTSEFKPGYSLHDTSVAVKIQSSSKST : :. . NP_001 PPSFEGKTNESSLSAKSEL 330 381 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:50:28 2016 done: Fri Nov 4 15:50:29 2016 Total Scan time: 7.720 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]