FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8819, 382 aa
1>>>pF1KB8819 382 - 382 aa - 382 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7630+/-0.000505; mu= 21.9172+/- 0.032
mean_var=219.0481+/-54.446, 0's: 0 Z-trim(112.6): 313 B-trim: 1245 in 1/51
Lambda= 0.086657
statistics sampled from 21218 (21655) to 21218 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.254), width: 16
Scan time: 8.260
The best scores are: opt bits E(85289)
NP_543022 (OMIM: 300407) polyadenylate-binding pro ( 382) 2565 334.4 2.8e-91
NP_001129126 (OMIM: 603407) polyadenylate-binding ( 631) 1623 217.0 9.6e-56
NP_003810 (OMIM: 603407) polyadenylate-binding pro ( 644) 1623 217.0 9.7e-56
NP_001129125 (OMIM: 603407) polyadenylate-binding ( 660) 1623 217.1 9.8e-56
XP_005250918 (OMIM: 604679) PREDICTED: polyadenyla ( 636) 1606 214.9 4.2e-55
NP_002559 (OMIM: 604679) polyadenylate-binding pro ( 636) 1606 214.9 4.2e-55
NP_112241 (OMIM: 604680) polyadenylate-binding pro ( 631) 1509 202.8 1.9e-51
NP_005841 (OMIM: 154400,605593) splicing factor 3B ( 424) 375 60.7 7.6e-09
NP_001311138 (OMIM: 168360) ELAV-like protein 4 is ( 352) 271 47.5 5.8e-05
NP_001311144 (OMIM: 168360) ELAV-like protein 4 is ( 358) 271 47.5 5.8e-05
XP_016856028 (OMIM: 168360) PREDICTED: ELAV-like p ( 359) 271 47.5 5.8e-05
NP_001311143 (OMIM: 168360) ELAV-like protein 4 is ( 365) 271 47.5 5.9e-05
NP_001311141 (OMIM: 168360) ELAV-like protein 4 is ( 365) 271 47.5 5.9e-05
NP_001138246 (OMIM: 168360) ELAV-like protein 4 is ( 366) 271 47.5 5.9e-05
NP_001138248 (OMIM: 168360) ELAV-like protein 4 is ( 366) 271 47.5 5.9e-05
NP_001138249 (OMIM: 168360) ELAV-like protein 4 is ( 369) 271 47.5 5.9e-05
NP_001281277 (OMIM: 168360) ELAV-like protein 4 is ( 371) 271 47.5 5.9e-05
XP_011539196 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 271 47.6 6e-05
XP_011539197 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 271 47.6 6e-05
XP_016856027 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 271 47.6 6e-05
NP_068771 (OMIM: 168360) ELAV-like protein 4 isofo ( 380) 271 47.6 6e-05
XP_011539195 (OMIM: 168360) PREDICTED: ELAV-like p ( 380) 271 47.6 6e-05
NP_001311137 (OMIM: 168360) ELAV-like protein 4 is ( 383) 271 47.6 6e-05
NP_001311142 (OMIM: 168360) ELAV-like protein 4 is ( 385) 271 47.6 6e-05
XP_011539192 (OMIM: 168360) PREDICTED: ELAV-like p ( 389) 271 47.6 6e-05
XP_006710474 (OMIM: 168360) PREDICTED: ELAV-like p ( 393) 271 47.6 6e-05
NP_001138247 (OMIM: 168360) ELAV-like protein 4 is ( 402) 271 47.6 6.1e-05
NP_001410 (OMIM: 603466) ELAV-like protein 1 [Homo ( 326) 270 47.3 6.1e-05
XP_011539191 (OMIM: 168360) PREDICTED: ELAV-like p ( 416) 271 47.6 6.2e-05
NP_001164666 (OMIM: 601673) ELAV-like protein 2 is ( 346) 269 47.2 6.8e-05
XP_016869913 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 269 47.2 6.8e-05
XP_016869914 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 269 47.2 6.8e-05
NP_001164668 (OMIM: 601673) ELAV-like protein 2 is ( 346) 269 47.2 6.8e-05
XP_016869911 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05
XP_016869912 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05
XP_016869908 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05
XP_016869910 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05
NP_004423 (OMIM: 601673) ELAV-like protein 2 isofo ( 359) 269 47.3 6.9e-05
XP_016869909 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05
XP_016869907 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
NP_115657 (OMIM: 603458) ELAV-like protein 3 isofo ( 360) 269 47.3 6.9e-05
XP_005251452 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_005251451 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_006716799 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_011516086 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_011516087 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_011516088 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_005251450 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05
XP_011526080 (OMIM: 603458) PREDICTED: ELAV-like p ( 366) 269 47.3 7e-05
NP_001411 (OMIM: 603458) ELAV-like protein 3 isofo ( 367) 269 47.3 7e-05
>>NP_543022 (OMIM: 300407) polyadenylate-binding protein (382 aa)
initn: 2565 init1: 2565 opt: 2565 Z-score: 1759.8 bits: 334.4 E(85289): 2.8e-91
Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
310 320 330 340 350 360
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
::::::::::::::::::::::
NP_543 MNGRIVGSKPLHVTLGQARRRC
370 380
>>NP_001129126 (OMIM: 603407) polyadenylate-binding prot (631 aa)
initn: 1809 init1: 825 opt: 1623 Z-score: 1121.7 bits: 217.0 E(85289): 9.6e-56
Smith-Waterman score: 1623; 66.6% identity (85.8% similar) in 365 aa overlap (15-379:8-371)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
: :.:::::: :::: :::.:: ::::. :.::: .:: ::
NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
:.::::. ::::: ::.:::::.:.:::.:.:::: : ::::::::.:::::::::::.
NP_001 YAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::. :::::::::::::::.:::::::.:::.. ::..:: .:::. ::.:.:.::::
NP_001 ALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
: .:: ::. .. . ::::..::.:...:::.::::: ..: : ::::.:: .:::::
NP_001 KSRKEREAELGAKAKE-FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
:::: :: :: :.::: ...:: :.::...:::::::.:: :::.:.::.:. .. ::
NP_001 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
:: .::::::.::.::::..::: ::::. ::::.: :..:::: ::::: ::::::: :
NP_001 GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTE
300 310 320 330 340 350
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
:::::::::::.:.:.: .
NP_001 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPA
360 370 380 390 400 410
>>NP_003810 (OMIM: 603407) polyadenylate-binding protein (644 aa)
initn: 1809 init1: 825 opt: 1623 Z-score: 1121.7 bits: 217.0 E(85289): 9.7e-56
Smith-Waterman score: 1623; 66.6% identity (85.8% similar) in 365 aa overlap (15-379:8-371)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
: :.:::::: :::: :::.:: ::::. :.::: .:: ::
NP_003 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
:.::::. ::::: ::.:::::.:.:::.:.:::: : ::::::::.:::::::::::.
NP_003 YAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::. :::::::::::::::.:::::::.:::.. ::..:: .:::. ::.:.:.::::
NP_003 ALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
: .:: ::. .. . ::::..::.:...:::.::::: ..: : ::::.:: .:::::
NP_003 KSRKEREAELGAKAKE-FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
:::: :: :: :.::: ...:: :.::...:::::::.:: :::.:.::.:. .. ::
NP_003 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
:: .::::::.::.::::..::: ::::. ::::.: :..:::: ::::: ::::::: :
NP_003 GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTE
300 310 320 330 340 350
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
:::::::::::.:.:.: .
NP_003 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPA
360 370 380 390 400 410
>>NP_001129125 (OMIM: 603407) polyadenylate-binding prot (660 aa)
initn: 1809 init1: 825 opt: 1623 Z-score: 1121.6 bits: 217.1 E(85289): 9.8e-56
Smith-Waterman score: 1623; 66.6% identity (85.8% similar) in 365 aa overlap (15-379:8-371)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
: :.:::::: :::: :::.:: ::::. :.::: .:: ::
NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
:.::::. ::::: ::.:::::.:.:::.:.:::: : ::::::::.:::::::::::.
NP_001 YAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::. :::::::::::::::.:::::::.:::.. ::..:: .:::. ::.:.:.::::
NP_001 ALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
: .:: ::. .. . ::::..::.:...:::.::::: ..: : ::::.:: .:::::
NP_001 KSRKEREAELGAKAKE-FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
:::: :: :: :.::: ...:: :.::...:::::::.:: :::.:.::.:. .. ::
NP_001 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
:: .::::::.::.::::..::: ::::. ::::.: :..:::: ::::: ::::::: :
NP_001 GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTE
300 310 320 330 340 350
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
:::::::::::.:.:.: .
NP_001 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPA
360 370 380 390 400 410
>>XP_005250918 (OMIM: 604679) PREDICTED: polyadenylate-b (636 aa)
initn: 1791 init1: 838 opt: 1606 Z-score: 1110.2 bits: 214.9 E(85289): 4.2e-55
Smith-Waterman score: 1606; 64.3% identity (84.5% similar) in 373 aa overlap (7-379:2-371)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
::.. . : :.:::::: ::::: :::.:: ::::. :.::: .:: ::
XP_005 MNPSAPS--YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
:.::::. ::::: ::.:::::.:.::: :.:::: : ::::::::::::::::::::.
XP_005 YAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::. :::::::::::::::.::::::..:::.. ::.::: .:::. ::.:.:.::::
XP_005 ALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
: .:: ::. .: . ::::..::.:.:.:::.::.:: ..::. ::::. : ::::::
XP_005 KSRKEREAELGARAKE-FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
:::: .: :: ::::: ...:: ..:: .::::::::.:: .::.:.::... . .:
XP_005 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
:: .:.::::. :.::.:..::: ::.:. :::::: :..:::: ::::: ::::::: :
XP_005 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE
300 310 320 330 340 350
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
::::::..:::.:.:.: .
XP_005 MNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAA
360 370 380 390 400 410
>>NP_002559 (OMIM: 604679) polyadenylate-binding protein (636 aa)
initn: 1791 init1: 838 opt: 1606 Z-score: 1110.2 bits: 214.9 E(85289): 4.2e-55
Smith-Waterman score: 1606; 64.3% identity (84.5% similar) in 373 aa overlap (7-379:2-371)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
::.. . : :.:::::: ::::: :::.:: ::::. :.::: .:: ::
NP_002 MNPSAPS--YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
:.::::. ::::: ::.:::::.:.::: :.:::: : ::::::::::::::::::::.
NP_002 YAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::. :::::::::::::::.::::::..:::.. ::.::: .:::. ::.:.:.::::
NP_002 ALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
: .:: ::. .: . ::::..::.:.:.:::.::.:: ..::. ::::. : ::::::
NP_002 KSRKEREAELGARAKE-FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
:::: .: :: ::::: ...:: ..:: .::::::::.:: .::.:.::... . .:
NP_002 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
:: .:.::::. :.::.:..::: ::.:. :::::: :..:::: ::::: ::::::: :
NP_002 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE
300 310 320 330 340 350
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
::::::..:::.:.:.: .
NP_002 MNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAA
360 370 380 390 400 410
>>NP_112241 (OMIM: 604680) polyadenylate-binding protein (631 aa)
initn: 1681 init1: 764 opt: 1509 Z-score: 1044.7 bits: 202.8 E(85289): 1.9e-51
Smith-Waterman score: 1509; 61.1% identity (82.0% similar) in 373 aa overlap (7-379:2-371)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
::. .: :.:::::: ::::: :::.:: ::::. ::::: .: . .
NP_112 MNPS--TPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSN
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
:.::::. ::: ::.:::::.:.::: :.:::: : ::::::::::.:::::::.:.
NP_112 YAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
::. :::::::::.::::.::::::..:::.. ::.::: .:::. ::.:.:.::.:
NP_112 ALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
: .:: ::. .: . : ::..::.:.:.:::.::.:: ..::. ::::. : ::::::
NP_112 KSRKEREAELGARAKE-FPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
:::: .: :: ::::: ...:: ..:: .::::::::.:: .::.: ::... . .:
NP_112 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
: .:.::::. :.::.:.. :: ::.:. :::::: :..:::: ::::: ::::::: :
NP_112 VVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE
300 310 320 330 340 350
370 380
pF1KB8 MNGRIVGSKPLHVTLGQARRRC
::::::..:::.:.:.: .
NP_112 MNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQN
360 370 380 390 400 410
>>NP_005841 (OMIM: 154400,605593) splicing factor 3B sub (424 aa)
initn: 441 init1: 187 opt: 375 Z-score: 279.8 bits: 60.7 E(85289): 7.6e-09
Smith-Waterman score: 375; 41.1% identity (66.9% similar) in 175 aa overlap (18-189:13-185)
10 20 30 40 50 60
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
:..::: :: :.: .:.. : :::. :.. .: :: . :
NP_005 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQG
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
::.:.: ::..:.. ::. . :::.:. .. .. :. :::: ::: ::..
NP_005 YGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGA-NIFIGNLDPEIDEK
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 ALFYLFSAFGNILSC-KVVCD-DNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYV
:. ::::: ::. :.. : :.: :::::...: :. :.. :: ::: : :: . :
NP_005 LLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 GRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK
. . : .. .:
NP_005 S-YAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLP
180 190 200 210 220 230
>>NP_001311138 (OMIM: 168360) ELAV-like protein 4 isofor (352 aa)
initn: 321 init1: 132 opt: 271 Z-score: 210.1 bits: 47.5 E(85289): 5.8e-05
Smith-Waterman score: 356; 27.3% identity (55.6% similar) in 322 aa overlap (6-280:33-351)
10 20 30
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLY
: .: :. : :. : ..:.. .
NP_001 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 KKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQ
. : : .. .. :: .: . ::::.::. : ::: :.::.: .. : ... ...
NP_001 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 PDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD-NG-SKGYAYVHFD
:.. ... :.....: :.. .. : ::: .: :.. ... :. .: :.: ....::
NP_001 PSSASIRDA--NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD
130 140 150 160 170 180
160 170 180
pF1KB8 SLAAANRAIWHMNG-----------VRLNNR-----------QVYVG---RFKFPEERAA
. :..:: .:: :.. : :.: . :. : .. :
NP_001 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQA
190 200 210 220 230 240
190 200 210 220
pF1KB8 EVRTR-------------------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVK
. : : .: .:: :.. : :. : .:: .: ...::
NP_001 Q-RFRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK
250 260 270 280 290
230 240 250 260 270 280
pF1KB8 VIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF
:::: ..: :::::: . ... : :. .:.: . .:: :. .: ..
NP_001 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB8 ERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCF
>>NP_001311144 (OMIM: 168360) ELAV-like protein 4 isofor (358 aa)
initn: 321 init1: 132 opt: 271 Z-score: 210.1 bits: 47.5 E(85289): 5.8e-05
Smith-Waterman score: 356; 27.3% identity (55.6% similar) in 322 aa overlap (6-280:39-357)
10 20 30
pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLY
: .: :. : :. : ..:.. .
NP_001 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 KKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQ
. : : .. .. :: .: . ::::.::. : ::: :.::.: .. : ... ...
NP_001 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 PDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD-NG-SKGYAYVHFD
:.. ... :.....: :.. .. : ::: .: :.. ... :. .: :.: ....::
NP_001 PSSASIRDA--NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD
130 140 150 160 170 180
160 170 180
pF1KB8 SLAAANRAIWHMNG-----------VRLNNR-----------QVYVG---RFKFPEERAA
. :..:: .:: :.. : :.: . :. : .. :
NP_001 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQA
190 200 210 220 230 240
190 200 210 220
pF1KB8 EVRTR-------------------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVK
. : : .: .:: :.. : :. : .:: .: ...::
NP_001 Q-RFRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK
250 260 270 280 290 300
230 240 250 260 270 280
pF1KB8 VIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF
:::: ..: :::::: . ... : :. .:.: . .:: :. .: ..
NP_001 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS
310 320 330 340 350
290 300 310 320 330 340
pF1KB8 ERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCF
382 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:51:03 2016 done: Fri Nov 4 15:51:04 2016
Total Scan time: 8.260 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]