FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8819, 382 aa 1>>>pF1KB8819 382 - 382 aa - 382 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7630+/-0.000505; mu= 21.9172+/- 0.032 mean_var=219.0481+/-54.446, 0's: 0 Z-trim(112.6): 313 B-trim: 1245 in 1/51 Lambda= 0.086657 statistics sampled from 21218 (21655) to 21218 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.254), width: 16 Scan time: 8.260 The best scores are: opt bits E(85289) NP_543022 (OMIM: 300407) polyadenylate-binding pro ( 382) 2565 334.4 2.8e-91 NP_001129126 (OMIM: 603407) polyadenylate-binding ( 631) 1623 217.0 9.6e-56 NP_003810 (OMIM: 603407) polyadenylate-binding pro ( 644) 1623 217.0 9.7e-56 NP_001129125 (OMIM: 603407) polyadenylate-binding ( 660) 1623 217.1 9.8e-56 XP_005250918 (OMIM: 604679) PREDICTED: polyadenyla ( 636) 1606 214.9 4.2e-55 NP_002559 (OMIM: 604679) polyadenylate-binding pro ( 636) 1606 214.9 4.2e-55 NP_112241 (OMIM: 604680) polyadenylate-binding pro ( 631) 1509 202.8 1.9e-51 NP_005841 (OMIM: 154400,605593) splicing factor 3B ( 424) 375 60.7 7.6e-09 NP_001311138 (OMIM: 168360) ELAV-like protein 4 is ( 352) 271 47.5 5.8e-05 NP_001311144 (OMIM: 168360) ELAV-like protein 4 is ( 358) 271 47.5 5.8e-05 XP_016856028 (OMIM: 168360) PREDICTED: ELAV-like p ( 359) 271 47.5 5.8e-05 NP_001311143 (OMIM: 168360) ELAV-like protein 4 is ( 365) 271 47.5 5.9e-05 NP_001311141 (OMIM: 168360) ELAV-like protein 4 is ( 365) 271 47.5 5.9e-05 NP_001138246 (OMIM: 168360) ELAV-like protein 4 is ( 366) 271 47.5 5.9e-05 NP_001138248 (OMIM: 168360) ELAV-like protein 4 is ( 366) 271 47.5 5.9e-05 NP_001138249 (OMIM: 168360) ELAV-like protein 4 is ( 369) 271 47.5 5.9e-05 NP_001281277 (OMIM: 168360) ELAV-like protein 4 is ( 371) 271 47.5 5.9e-05 XP_011539196 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 271 47.6 6e-05 XP_011539197 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 271 47.6 6e-05 XP_016856027 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 271 47.6 6e-05 NP_068771 (OMIM: 168360) ELAV-like protein 4 isofo ( 380) 271 47.6 6e-05 XP_011539195 (OMIM: 168360) PREDICTED: ELAV-like p ( 380) 271 47.6 6e-05 NP_001311137 (OMIM: 168360) ELAV-like protein 4 is ( 383) 271 47.6 6e-05 NP_001311142 (OMIM: 168360) ELAV-like protein 4 is ( 385) 271 47.6 6e-05 XP_011539192 (OMIM: 168360) PREDICTED: ELAV-like p ( 389) 271 47.6 6e-05 XP_006710474 (OMIM: 168360) PREDICTED: ELAV-like p ( 393) 271 47.6 6e-05 NP_001138247 (OMIM: 168360) ELAV-like protein 4 is ( 402) 271 47.6 6.1e-05 NP_001410 (OMIM: 603466) ELAV-like protein 1 [Homo ( 326) 270 47.3 6.1e-05 XP_011539191 (OMIM: 168360) PREDICTED: ELAV-like p ( 416) 271 47.6 6.2e-05 NP_001164666 (OMIM: 601673) ELAV-like protein 2 is ( 346) 269 47.2 6.8e-05 XP_016869913 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 269 47.2 6.8e-05 XP_016869914 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 269 47.2 6.8e-05 NP_001164668 (OMIM: 601673) ELAV-like protein 2 is ( 346) 269 47.2 6.8e-05 XP_016869911 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05 XP_016869912 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05 XP_016869908 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05 XP_016869910 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05 NP_004423 (OMIM: 601673) ELAV-like protein 2 isofo ( 359) 269 47.3 6.9e-05 XP_016869909 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 269 47.3 6.9e-05 XP_016869907 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 NP_115657 (OMIM: 603458) ELAV-like protein 3 isofo ( 360) 269 47.3 6.9e-05 XP_005251452 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_005251451 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_006716799 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_011516086 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_011516087 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_011516088 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_005251450 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 269 47.3 6.9e-05 XP_011526080 (OMIM: 603458) PREDICTED: ELAV-like p ( 366) 269 47.3 7e-05 NP_001411 (OMIM: 603458) ELAV-like protein 3 isofo ( 367) 269 47.3 7e-05 >>NP_543022 (OMIM: 300407) polyadenylate-binding protein (382 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 1759.8 bits: 334.4 E(85289): 2.8e-91 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE 310 320 330 340 350 360 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC :::::::::::::::::::::: NP_543 MNGRIVGSKPLHVTLGQARRRC 370 380 >>NP_001129126 (OMIM: 603407) polyadenylate-binding prot (631 aa) initn: 1809 init1: 825 opt: 1623 Z-score: 1121.7 bits: 217.0 E(85289): 9.6e-56 Smith-Waterman score: 1623; 66.6% identity (85.8% similar) in 365 aa overlap (15-379:8-371) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG : :.:::::: :::: :::.:: ::::. :.::: .:: :: NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :.::::. ::::: ::.:::::.:.:::.:.:::: : ::::::::.:::::::::::. NP_001 YAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF ::. :::::::::::::::.:::::::.:::.. ::..:: .:::. ::.:.:.:::: NP_001 ALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG : .:: ::. .. . ::::..::.:...:::.::::: ..: : ::::.:: .::::: NP_001 KSRKEREAELGAKAKE-FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::: :: :: :.::: ...:: :.::...:::::::.:: :::.:.::.:. .. :: NP_001 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE :: .::::::.::.::::..::: ::::. ::::.: :..:::: ::::: ::::::: : NP_001 GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTE 300 310 320 330 340 350 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC :::::::::::.:.:.: . NP_001 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPA 360 370 380 390 400 410 >>NP_003810 (OMIM: 603407) polyadenylate-binding protein (644 aa) initn: 1809 init1: 825 opt: 1623 Z-score: 1121.7 bits: 217.0 E(85289): 9.7e-56 Smith-Waterman score: 1623; 66.6% identity (85.8% similar) in 365 aa overlap (15-379:8-371) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG : :.:::::: :::: :::.:: ::::. :.::: .:: :: NP_003 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :.::::. ::::: ::.:::::.:.:::.:.:::: : ::::::::.:::::::::::. NP_003 YAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF ::. :::::::::::::::.:::::::.:::.. ::..:: .:::. ::.:.:.:::: NP_003 ALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG : .:: ::. .. . ::::..::.:...:::.::::: ..: : ::::.:: .::::: NP_003 KSRKEREAELGAKAKE-FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::: :: :: :.::: ...:: :.::...:::::::.:: :::.:.::.:. .. :: NP_003 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE :: .::::::.::.::::..::: ::::. ::::.: :..:::: ::::: ::::::: : NP_003 GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTE 300 310 320 330 340 350 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC :::::::::::.:.:.: . NP_003 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPA 360 370 380 390 400 410 >>NP_001129125 (OMIM: 603407) polyadenylate-binding prot (660 aa) initn: 1809 init1: 825 opt: 1623 Z-score: 1121.6 bits: 217.1 E(85289): 9.8e-56 Smith-Waterman score: 1623; 66.6% identity (85.8% similar) in 365 aa overlap (15-379:8-371) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG : :.:::::: :::: :::.:: ::::. :.::: .:: :: NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :.::::. ::::: ::.:::::.:.:::.:.:::: : ::::::::.:::::::::::. NP_001 YAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF ::. :::::::::::::::.:::::::.:::.. ::..:: .:::. ::.:.:.:::: NP_001 ALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG : .:: ::. .. . ::::..::.:...:::.::::: ..: : ::::.:: .::::: NP_001 KSRKEREAELGAKAKE-FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::: :: :: :.::: ...:: :.::...:::::::.:: :::.:.::.:. .. :: NP_001 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE :: .::::::.::.::::..::: ::::. ::::.: :..:::: ::::: ::::::: : NP_001 GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTE 300 310 320 330 340 350 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC :::::::::::.:.:.: . NP_001 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPA 360 370 380 390 400 410 >>XP_005250918 (OMIM: 604679) PREDICTED: polyadenylate-b (636 aa) initn: 1791 init1: 838 opt: 1606 Z-score: 1110.2 bits: 214.9 E(85289): 4.2e-55 Smith-Waterman score: 1606; 64.3% identity (84.5% similar) in 373 aa overlap (7-379:2-371) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG ::.. . : :.:::::: ::::: :::.:: ::::. :.::: .:: :: XP_005 MNPSAPS--YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :.::::. ::::: ::.:::::.:.::: :.:::: : ::::::::::::::::::::. XP_005 YAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF ::. :::::::::::::::.::::::..:::.. ::.::: .:::. ::.:.:.:::: XP_005 ALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG : .:: ::. .: . ::::..::.:.:.:::.::.:: ..::. ::::. : :::::: XP_005 KSRKEREAELGARAKE-FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::: .: :: ::::: ...:: ..:: .::::::::.:: .::.:.::... . .: XP_005 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE :: .:.::::. :.::.:..::: ::.:. :::::: :..:::: ::::: ::::::: : XP_005 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE 300 310 320 330 340 350 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC ::::::..:::.:.:.: . XP_005 MNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAA 360 370 380 390 400 410 >>NP_002559 (OMIM: 604679) polyadenylate-binding protein (636 aa) initn: 1791 init1: 838 opt: 1606 Z-score: 1110.2 bits: 214.9 E(85289): 4.2e-55 Smith-Waterman score: 1606; 64.3% identity (84.5% similar) in 373 aa overlap (7-379:2-371) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG ::.. . : :.:::::: ::::: :::.:: ::::. :.::: .:: :: NP_002 MNPSAPS--YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :.::::. ::::: ::.:::::.:.::: :.:::: : ::::::::::::::::::::. NP_002 YAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF ::. :::::::::::::::.::::::..:::.. ::.::: .:::. ::.:.:.:::: NP_002 ALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG : .:: ::. .: . ::::..::.:.:.:::.::.:: ..::. ::::. : :::::: NP_002 KSRKEREAELGARAKE-FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::: .: :: ::::: ...:: ..:: .::::::::.:: .::.:.::... . .: NP_002 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE :: .:.::::. :.::.:..::: ::.:. :::::: :..:::: ::::: ::::::: : NP_002 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE 300 310 320 330 340 350 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC ::::::..:::.:.:.: . NP_002 MNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAA 360 370 380 390 400 410 >>NP_112241 (OMIM: 604680) polyadenylate-binding protein (631 aa) initn: 1681 init1: 764 opt: 1509 Z-score: 1044.7 bits: 202.8 E(85289): 1.9e-51 Smith-Waterman score: 1509; 61.1% identity (82.0% similar) in 373 aa overlap (7-379:2-371) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG ::. .: :.:::::: ::::: :::.:: ::::. ::::: .: . . NP_112 MNPS--TPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSN 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR :.::::. ::: ::.:::::.:.::: :.:::: : ::::::::::.:::::::.:. NP_112 YAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF ::. :::::::::.::::.::::::..:::.. ::.::: .:::. ::.:.:.::.: NP_112 ALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG : .:: ::. .: . : ::..::.:.:.:::.::.:: ..::. ::::. : :::::: NP_112 KSRKEREAELGARAKE-FPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP :::: .: :: ::::: ...:: ..:: .::::::::.:: .::.: ::... . .: NP_112 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE : .:.::::. :.::.:.. :: ::.:. :::::: :..:::: ::::: ::::::: : NP_112 VVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE 300 310 320 330 340 350 370 380 pF1KB8 MNGRIVGSKPLHVTLGQARRRC ::::::..:::.:.:.: . NP_112 MNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQN 360 370 380 390 400 410 >>NP_005841 (OMIM: 154400,605593) splicing factor 3B sub (424 aa) initn: 441 init1: 187 opt: 375 Z-score: 279.8 bits: 60.7 E(85289): 7.6e-09 Smith-Waterman score: 375; 41.1% identity (66.9% similar) in 175 aa overlap (18-189:13-185) 10 20 30 40 50 60 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG :..::: :: :.: .:.. : :::. :.. .: :: . : NP_005 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQG 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR ::.:.: ::..:.. ::. . :::.:. .. .. :. :::: ::: ::.. NP_005 YGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGA-NIFIGNLDPEIDEK 60 70 80 90 100 110 130 140 150 160 170 pF1KB8 ALFYLFSAFGNILSC-KVVCD-DNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYV :. ::::: ::. :.. : :.: :::::...: :. :.. :: ::: : :: . : NP_005 LLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 GRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK . . : .. .: NP_005 S-YAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLP 180 190 200 210 220 230 >>NP_001311138 (OMIM: 168360) ELAV-like protein 4 isofor (352 aa) initn: 321 init1: 132 opt: 271 Z-score: 210.1 bits: 47.5 E(85289): 5.8e-05 Smith-Waterman score: 356; 27.3% identity (55.6% similar) in 322 aa overlap (6-280:33-351) 10 20 30 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLY : .: :. : :. : ..:.. . NP_001 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 KKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQ . : : .. .. :: .: . ::::.::. : ::: :.::.: .. : ... ... NP_001 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 PDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD-NG-SKGYAYVHFD :.. ... :.....: :.. .. : ::: .: :.. ... :. .: :.: ....:: NP_001 PSSASIRDA--NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 130 140 150 160 170 180 160 170 180 pF1KB8 SLAAANRAIWHMNG-----------VRLNNR-----------QVYVG---RFKFPEERAA . :..:: .:: :.. : :.: . :. : .. : NP_001 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQA 190 200 210 220 230 240 190 200 210 220 pF1KB8 EVRTR-------------------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVK . : : .: .:: :.. : :. : .:: .: ...:: NP_001 Q-RFRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 250 260 270 280 290 230 240 250 260 270 280 pF1KB8 VIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF :::: ..: :::::: . ... : :. .:.: . .:: :. .: .. NP_001 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB8 ERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCF >>NP_001311144 (OMIM: 168360) ELAV-like protein 4 isofor (358 aa) initn: 321 init1: 132 opt: 271 Z-score: 210.1 bits: 47.5 E(85289): 5.8e-05 Smith-Waterman score: 356; 27.3% identity (55.6% similar) in 322 aa overlap (6-280:39-357) 10 20 30 pF1KB8 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLY : .: :. : :. : ..:.. . NP_001 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 KKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQ . : : .. .. :: .: . ::::.::. : ::: :.::.: .. : ... ... NP_001 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 PDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD-NG-SKGYAYVHFD :.. ... :.....: :.. .. : ::: .: :.. ... :. .: :.: ....:: NP_001 PSSASIRDA--NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 130 140 150 160 170 180 160 170 180 pF1KB8 SLAAANRAIWHMNG-----------VRLNNR-----------QVYVG---RFKFPEERAA . :..:: .:: :.. : :.: . :. : .. : NP_001 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQA 190 200 210 220 230 240 190 200 210 220 pF1KB8 EVRTR-------------------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVK . : : .: .:: :.. : :. : .:: .: ...:: NP_001 Q-RFRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB8 VIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF :::: ..: :::::: . ... : :. .:.: . .:: :. .: .. NP_001 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 310 320 330 340 350 290 300 310 320 330 340 pF1KB8 ERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCF 382 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:51:03 2016 done: Fri Nov 4 15:51:04 2016 Total Scan time: 8.260 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]