FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8820, 384 aa 1>>>pF1KB8820 384 - 384 aa - 384 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8824+/-0.000432; mu= 19.3441+/- 0.027 mean_var=90.6406+/-20.529, 0's: 0 Z-trim(110.5): 589 B-trim: 989 in 1/55 Lambda= 0.134714 statistics sampled from 18225 (18901) to 18225 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.578), E-opt: 0.2 (0.222), width: 16 Scan time: 8.380 The best scores are: opt bits E(85289) NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 2555 507.3 2.4e-143 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 888 183.3 7.7e-46 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 888 183.3 7.7e-46 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 839 173.8 5.6e-43 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 798 165.8 1.4e-40 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 798 165.8 1.4e-40 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 783 162.9 1.1e-39 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 782 162.7 1.2e-39 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 782 162.7 1.2e-39 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 782 162.7 1.2e-39 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 782 162.7 1.2e-39 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 782 162.7 1.2e-39 NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 782 162.7 1.3e-39 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 782 162.7 1.3e-39 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 782 162.8 1.3e-39 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 782 162.8 1.3e-39 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 766 159.6 1e-38 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 766 159.6 1e-38 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 734 153.4 7.9e-37 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 734 153.4 7.9e-37 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 734 153.4 7.9e-37 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 734 153.4 7.9e-37 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 734 153.4 7.9e-37 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 734 153.4 7.9e-37 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 731 152.8 1.2e-36 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 731 152.8 1.2e-36 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 731 152.8 1.2e-36 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 731 152.8 1.2e-36 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 731 152.8 1.2e-36 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 731 152.8 1.2e-36 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 731 152.9 1.3e-36 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 731 152.9 1.3e-36 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 726 151.9 2.4e-36 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 726 151.9 2.4e-36 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 722 151.1 4e-36 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 722 151.1 4e-36 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 705 147.8 3.9e-35 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 705 147.8 3.9e-35 NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 696 146.0 1.3e-34 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 688 144.4 3.8e-34 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 683 143.5 7.5e-34 NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 679 142.7 1.3e-33 NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 679 142.7 1.3e-33 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 668 140.6 5.8e-33 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 668 140.6 5.8e-33 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 668 140.6 5.8e-33 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 668 140.6 5.9e-33 NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 619 131.0 3.9e-30 NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 619 131.1 4.3e-30 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 612 129.6 9.9e-30 >>NP_001287 (OMIM: 602648) atypical chemokine receptor 2 (384 aa) initn: 2555 init1: 2555 opt: 2555 Z-score: 2694.6 bits: 507.3 E(85289): 2.4e-143 Smith-Waterman score: 2555; 99.7% identity (99.7% similar) in 384 aa overlap (1-384:1-384) 10 20 30 40 50 60 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 STLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMT 310 320 330 340 350 360 370 380 pF1KB8 GMNDLGERQSENSPNKEDVGNKSA :::::::::::: ::::::::::: NP_001 GMNDLGERQSENYPNKEDVGNKSA 370 380 >>XP_016861176 (OMIM: 604836) PREDICTED: C-C chemokine r (360 aa) initn: 821 init1: 468 opt: 888 Z-score: 944.0 bits: 183.3 E(85289): 7.7e-46 Smith-Waterman score: 888; 41.3% identity (73.6% similar) in 322 aa overlap (12-332:4-324) 10 20 30 40 50 pF1KB8 MAATASPQPLATEDADSE-NSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVL :. ::. . :.: :: : : :... .::..::: .:::.::. XP_016 MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKM :: :: ....::..: : :...::::::::.:::. .::::: .: .:::: :::: XP_016 GLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD .: .: ..:::::::. ::.:.:: :::: : :: . ... . .:.:.. .:.: XP_016 ISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVR ..: . . . .. :.. .. ..: ::.. .. :.::...:: :.: :: : .: . XP_016 FLFSTCYTERNHTY-CKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQH 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTES . ...:.:. :.:: :. .: :::..:::.::..:.:. .: ..::::.:.::. XP_016 CKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATET 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 IAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEM .::.:::..::.: : ...::.:. .. . : XP_016 LAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQST 300 310 320 330 340 350 360 370 380 pF1KB8 TGMNDLGERQSENSPNKEDVGNKSA XP_016 MDHDLHDAL 360 >>NP_005499 (OMIM: 604836) C-C chemokine receptor type 4 (360 aa) initn: 821 init1: 468 opt: 888 Z-score: 944.0 bits: 183.3 E(85289): 7.7e-46 Smith-Waterman score: 888; 41.3% identity (73.6% similar) in 322 aa overlap (12-332:4-324) 10 20 30 40 50 pF1KB8 MAATASPQPLATEDADSE-NSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVL :. ::. . :.: :: : : :... .::..::: .:::.::. NP_005 MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKM :: :: ....::..: : :...::::::::.:::. .::::: .: .:::: :::: NP_005 GLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD .: .: ..:::::::. ::.:.:: :::: : :: . ... . .:.:.. .:.: NP_005 ISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVR ..: . . . .. :.. .. ..: ::.. .. :.::...:: :.: :: : .: . NP_005 FLFSTCYTERNHTY-CKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQH 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTES . ...:.:. :.:: :. .: :::..:::.::..:.:. .: ..::::.:.::. NP_005 CKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATET 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 IAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEM .::.:::..::.: : ...::.:. .. . : NP_005 LAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQST 300 310 320 330 340 350 360 370 380 pF1KB8 TGMNDLGERQSENSPNKEDVGNKSA NP_005 MDHDLHDAL 360 >>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1 (355 aa) initn: 783 init1: 559 opt: 839 Z-score: 892.6 bits: 173.8 E(85289): 5.6e-43 Smith-Waterman score: 839; 39.6% identity (68.0% similar) in 359 aa overlap (9-360:4-352) 10 20 30 40 50 60 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLG : .::: :. . .:: : . :.: .:: .:: .:::.::.: NP_001 METPNTTEDYDTTTE----FDYGDATP---CQKVNERAFGAQLLPPLYSLVFVIG 10 20 30 40 70 80 90 100 110 pF1KB8 LSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFW-GISVAWHWVFGSFLCKM : ::.:...::..: . :. :::::::::.:::: ::::: .. ::::. .::. NP_001 LVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD .: .: ..:: :::: ...:.:: :::: : :: . ... . :.::... .:.: NP_001 LSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTI--WKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVL . : .:. . .: : : .. :::: .. ::.:..::::.::. :. : .: NP_001 LYFSKTQWEFTH-HTCSLHFP-HESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKIL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 VRLRPA-GQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQV .: :: ...:... .... ::..: :::::... .. :. .:: :.::: :.:: NP_001 LR-RPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 TESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLA---PGTAQASLSSCSESSIL :: ::. ::: .:..::: ..:::.::. .. .. ::. : . : : .: NP_001 TEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPS 290 300 310 320 330 340 360 370 380 pF1KB8 TAQEEMTGMNDLGERQSENSPNKEDVGNKSA :...:.. NP_001 TGEHELSAGF 350 >>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ (360 aa) initn: 682 init1: 378 opt: 798 Z-score: 849.4 bits: 165.8 E(85289): 1.4e-40 Smith-Waterman score: 798; 38.2% identity (74.4% similar) in 317 aa overlap (12-327:13-320) 10 20 30 40 50 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVL :... : ..:. ::: :.: : ..: .:: .:::.:.. NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAP-----CHKFDVKQIGAQLLPPLYSLVFIF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKM :. ::.:....:. . ...:::::::::.::::.:::.:. :.: .::::. .::. NP_001 GFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD . :: :....::::: ...:.:: :::: . :: . ... ..:.: :.. .:.: NP_001 FTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVR ..:.. ... . :. : : .: :. : ...:.::..:::: :.. :: : .:.: NP_001 IIFTKCQKEDS-VYVCGPYFP-RG--WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LRPAGQ-GRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTE : . ::... ......:..: :::....:.:. .. ..::: ...:: : :::: NP_001 CRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEE .... :::..::.::: ...::.::..:. NP_001 TLGMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPST 300 310 320 330 340 350 >>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r (360 aa) initn: 682 init1: 378 opt: 798 Z-score: 849.4 bits: 165.8 E(85289): 1.4e-40 Smith-Waterman score: 798; 38.2% identity (74.4% similar) in 317 aa overlap (12-327:13-320) 10 20 30 40 50 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVL :... : ..:. ::: :.: : ..: .:: .:::.:.. XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAP-----CHKFDVKQIGAQLLPPLYSLVFIF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKM :. ::.:....:. . ...:::::::::.::::.:::.:. :.: .::::. .::. XP_011 GFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD . :: :....::::: ...:.:: :::: . :: . ... ..:.: :.. .:.: XP_011 FTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVR ..:.. ... . :. : : .: :. : ...:.::..:::: :.. :: : .:.: XP_011 IIFTKCQKEDS-VYVCGPYFP-RG--WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LRPAGQ-GRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTE : . ::... ......:..: :::....:.:. .. ..::: ...:: : :::: XP_011 CRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEE .... :::..::.::: ...::.::..:. XP_011 TLGMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPST 300 310 320 330 340 350 >>NP_001158152 (OMIM: 601268) C-C chemokine receptor typ (373 aa) initn: 737 init1: 506 opt: 783 Z-score: 833.5 bits: 162.9 E(85289): 1.1e-39 Smith-Waterman score: 783; 37.0% identity (69.1% similar) in 362 aa overlap (8-360:13-370) 10 20 30 40 50 pF1KB8 MAATASPQPLATEDADSENS--SFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFY .: .: . : .. .: .: :.:. .::.: . .. :.: .: NP_001 MPFGIRMLLRAHKPGRSEMTTSLDTVETFGTTSYYDDVG-LLCEKADTRALMAQFVPPLY 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 SLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWH-WVF ::.:..:: ::....:.:..: : :..:::::::::.:::::::::: : : ::: NP_001 SLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVS : .::..: .: ..:: :::: ...:.:: :::: : :: . ... . ..:... NP_001 GHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LAVSIPDMVFVQTHENPKGVWNCHADFGGHGTI--WKLFLRFQQNLLGFLLPLLAMIFFY . ...:...: .:.: . . : : . . :. :. : ...... ..::::.: . : NP_001 VLAALPEFIFYETEELFEETL-CSALYP-EDTVYSWRHFHTLRMTIFCLVLPLLVMAICY 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 SRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGN-CEVSQH . : .:.: . .:... .....::..: :::....: . .. .::: :: :.: NP_001 TGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSI-LFGNDCERSKH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLA---PGTAQASLSS :: .. ::: ::. :::..:..::: ..:::.::. :. : ::. : . .: NP_001 LDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLER 300 310 320 330 340 350 350 360 370 380 pF1KB8 CSESSILTAQEEMTGMNDLGERQSENSPNKEDVGNKSA : : ::. :.. NP_001 TSSVSPSTAEPELSIVF 360 370 >>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa) initn: 768 init1: 406 opt: 782 Z-score: 832.7 bits: 162.7 E(85289): 1.2e-39 Smith-Waterman score: 782; 35.5% identity (68.1% similar) in 332 aa overlap (20-351:13-339) 10 20 30 40 50 60 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLG ...:: : .. : . . . ::..: ::: :.::.. NP_005 MDYTLDLSVTTVTDYYYPDIFSSP----CDAELIQTNGKLLLAVFYCLLFVFS 10 20 30 40 70 80 90 100 110 120 pF1KB8 LSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMV : :: :...::. : ....::::::.:.:::. ..:: . .::::. .::.: NP_005 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 STLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDM : .: :.:::..:::. ::.:.:: .::: ..:: . : :: ... ..:: . NP_005 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 VFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRL :: :. . :: .:.. .. . ::.: :..:.::.:.:. ..: : .: : : NP_005 VFYQV-ASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 RPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESI . .. .:.... .:.: ...: :.:..::: .: ..... .: .::.: :: .::: : NP_005 QNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 AFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMT .: ::: .:..::: ...:...:. .. . . : :: .:: NP_005 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRS 290 300 310 320 330 340 370 380 pF1KB8 GMNDLGERQSENSPNKEDVGNKSA NP_005 SSVDYIL 350 >>XP_006713023 (OMIM: 601268) PREDICTED: C-C chemokine r (355 aa) initn: 737 init1: 506 opt: 782 Z-score: 832.7 bits: 162.7 E(85289): 1.2e-39 Smith-Waterman score: 782; 37.8% identity (69.7% similar) in 347 aa overlap (21-360:10-352) 10 20 30 40 50 60 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLG .: .: :.:. .::.: . .. :.: .:::.:..: XP_006 MTTSLDTVETFGTTSYYDDVG-LLCEKADTRALMAQFVPPLYSLVFTVG 10 20 30 40 70 80 90 100 110 pF1KB8 LSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWH-WVFGSFLCKM : ::....:.:..: : :..:::::::::.:::::::::: : : :::: .::. XP_006 LLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD .: .: ..:: :::: ...:.:: :::: : :: . ... . ..:.... ...:. XP_006 LSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPE 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTI--WKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVL ..: .:.: . . : : . . :. :. : ...... ..::::.: . :. : .: XP_006 FIFYETEELFEETL-CSALYP-EDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 VRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGN-CEVSQHLDYALQV .: . .:... .....::..: :::....: . .. .::: :: :.::: .. : XP_006 LRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSI-LFGNDCERSKHLDLVMLV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 TESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLA---PGTAQASLSSCSESSIL :: ::. :::..:..::: ..:::.::. :. : ::. : . .: : : XP_006 TEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPS 290 300 310 320 330 340 360 370 380 pF1KB8 TAQEEMTGMNDLGERQSENSPNKEDVGNKSA ::. :.. XP_006 TAEPELSIVF 350 >>NP_001828 (OMIM: 601268) C-C chemokine receptor type 3 (355 aa) initn: 737 init1: 506 opt: 782 Z-score: 832.7 bits: 162.7 E(85289): 1.2e-39 Smith-Waterman score: 782; 37.8% identity (69.7% similar) in 347 aa overlap (21-360:10-352) 10 20 30 40 50 60 pF1KB8 MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLG .: .: :.:. .::.: . .. :.: .:::.:..: NP_001 MTTSLDTVETFGTTSYYDDVG-LLCEKADTRALMAQFVPPLYSLVFTVG 10 20 30 40 70 80 90 100 110 pF1KB8 LSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWH-WVFGSFLCKM : ::....:.:..: : :..:::::::::.:::::::::: : : :::: .::. NP_001 LLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 VSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPD .: .: ..:: :::: ...:.:: :::: : :: . ... . ..:.... ...:. NP_001 LSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPE 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 MVFVQTHENPKGVWNCHADFGGHGTI--WKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVL ..: .:.: . . : : . . :. :. : ...... ..::::.: . :. : .: NP_001 FIFYETEELFEETL-CSALYP-EDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 VRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGN-CEVSQHLDYALQV .: . .:... .....::..: :::....: . .. .::: :: :.::: .. : NP_001 LRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSI-LFGNDCERSKHLDLVMLV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 TESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLA---PGTAQASLSSCSESSIL :: ::. :::..:..::: ..:::.::. :. : ::. : . .: : : NP_001 TEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPS 290 300 310 320 330 340 360 370 380 pF1KB8 TAQEEMTGMNDLGERQSENSPNKEDVGNKSA ::. :.. NP_001 TAEPELSIVF 350 384 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:51:39 2016 done: Fri Nov 4 15:51:41 2016 Total Scan time: 8.380 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]