Result of FASTA (omim) for
pF1KB8822
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8822, 396 aa
1>>>pF1KB8822 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9862+/-0.000428; mu= 14.8297+/- 0.027
mean_var=135.4284+/-34.193, 0's: 0 Z-trim(113.4): 492 B-trim: 1235 in 1/54
Lambda= 0.110210
statistics sampled from 22079 (22717) to 22079 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.266), width: 16
Scan time: 7.790
The best scores are: opt bits E(85289)
XP_011536797 (OMIM: 606383) PREDICTED: G-protein c ( 396) 2616 427.9 2.1e-119
NP_065103 (OMIM: 606383) G-protein coupled recepto ( 396) 2616 427.9 2.1e-119
NP_000787 (OMIM: 126451,181500,190300) D(3) dopami ( 400) 334 65.1 3.5e-10
XP_016861318 (OMIM: 126451,181500,190300) PREDICTE ( 400) 334 65.1 3.5e-10
NP_001269492 (OMIM: 126451,181500,190300) D(3) dop ( 400) 334 65.1 3.5e-10
NP_001277738 (OMIM: 126451,181500,190300) D(3) dop ( 400) 334 65.1 3.5e-10
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 297 59.1 1.8e-08
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 297 59.1 1.8e-08
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 297 59.1 2e-08
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 297 59.2 2e-08
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 297 59.2 2.1e-08
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 297 59.3 2.5e-08
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 297 59.3 2.6e-08
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 286 57.3 5.9e-08
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 286 57.3 6e-08
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 286 57.3 6.1e-08
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 286 57.4 6.3e-08
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 286 57.4 6.6e-08
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 286 57.4 6.6e-08
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 286 57.5 7.3e-08
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 286 57.5 7.3e-08
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 286 57.5 7.6e-08
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 286 57.5 7.7e-08
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 286 57.5 7.8e-08
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 286 57.5 7.8e-08
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 286 57.5 7.8e-08
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 286 57.5 7.8e-08
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 268 54.7 5.7e-07
NP_057658 (OMIM: 126450,159900) D(2) dopamine rece ( 414) 267 54.4 5.8e-07
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 268 54.7 6.1e-07
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 265 54.1 7.4e-07
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 265 54.1 7.6e-07
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 265 54.2 7.9e-07
NP_004215 (OMIM: 300207) melatonin-related recepto ( 617) 264 54.1 1e-06
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 261 53.6 1.4e-06
XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytr ( 365) 253 52.1 2.5e-06
NP_000856 (OMIM: 182132) 5-hydroxytryptamine recep ( 365) 253 52.1 2.5e-06
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445) 254 52.4 2.5e-06
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 254 52.4 2.5e-06
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445) 254 52.4 2.5e-06
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445) 254 52.4 2.5e-06
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 254 52.4 2.5e-06
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 254 52.4 2.6e-06
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 254 52.4 2.6e-06
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 254 52.4 2.6e-06
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 253 52.2 2.8e-06
XP_016882096 (OMIM: 600551) PREDICTED: G-protein c ( 362) 251 51.8 3.1e-06
NP_005273 (OMIM: 600551) G-protein coupled recepto ( 362) 251 51.8 3.1e-06
XP_016882097 (OMIM: 600551) PREDICTED: G-protein c ( 362) 251 51.8 3.1e-06
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 251 51.8 3.2e-06
>>XP_011536797 (OMIM: 606383) PREDICTED: G-protein coupl (396 aa)
initn: 2616 init1: 2616 opt: 2616 Z-score: 2264.7 bits: 427.9 E(85289): 2.1e-119
Smith-Waterman score: 2616; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB8 MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
310 320 330 340 350 360
370 380 390
pF1KB8 LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
::::::::::::::::::::::::::::::::::::
XP_011 LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
370 380 390
>>NP_065103 (OMIM: 606383) G-protein coupled receptor 84 (396 aa)
initn: 2616 init1: 2616 opt: 2616 Z-score: 2264.7 bits: 427.9 E(85289): 2.1e-119
Smith-Waterman score: 2616; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB8 MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
310 320 330 340 350 360
370 380 390
pF1KB8 LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
::::::::::::::::::::::::::::::::::::
NP_065 LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
370 380 390
>>NP_000787 (OMIM: 126451,181500,190300) D(3) dopamine r (400 aa)
initn: 284 init1: 92 opt: 334 Z-score: 303.8 bits: 65.1 E(85289): 3.5e-10
Smith-Waterman score: 334; 26.0% identity (55.5% similar) in 411 aa overlap (4-385:8-398)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLG------YRYVAVSW-GVVVAVTGTVGNVLTLLALAIQP
:. :..: :. : . : :.:. ....:.. :: :. .:. .
NP_000 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIV--FGNGLVCMAVLKER
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLH---WRTGATFCRVFGLLLFASNSV
:.: : :...:..:::: ::..:. : ::.. : . : :: : ..
NP_000 ALQTTTNYLVVSLAVADLLVATLVMPWVV--YLEVTGGVWNFSRICCDVFVTLDVMMCTA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SILTLCLIALGRYLLIAHPKLFPQVF---SAKGIVLALVSTWVVGVASFAPLWPIYILV-
:::.:: :.. :: .. : . . : . ..: ....::.. : :: . .
NP_000 SILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTG
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 -PVVCTCSF-DRIRGRPYTTILMGIYFVLGLSSV---GIFYCLIHRQVKRAAQALDQYKL
:.::. : : . :.... ..:. .:.. . :. : .:. :: : . .
NP_000 DPTVCSISNPDFV---IYSSVV-SFYLPFGVTVLVYARIYVVLKQRRRKRI---LTRQNS
180 190 200 210 220
220 230 240 250 260 270
pF1KB8 RQASIHSNHVARTDEAMPG-----RFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSS
. :.. . .: :. :. . . : ::: :.. . .. . : .
NP_000 QCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGP--GFQER---GGELKREEKTRN
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB8 EVGDQINSKRAKQMAEKSPPEASA--KAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFAL
.. : : . .. . : . :. : :.. : .: . :.:.: :. : .
NP_000 SLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQ-PRGVPLREK---KATQMVAIVLGAFIV
290 300 310 320 330 340
340 350 360 370 380
pF1KB8 SYIPFLLLNILDARVQAPRVVHMLAANLTWL---NGCINPVLYAAMNRQFRQAYGSILKR
..::.: ..:... :. .: : . ::: :. .:::.:...: .::.:. .::
NP_000 CWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
350 360 370 380 390 400
390
pF1KB8 GPRSFHRLH
>>XP_016861318 (OMIM: 126451,181500,190300) PREDICTED: D (400 aa)
initn: 284 init1: 92 opt: 334 Z-score: 303.8 bits: 65.1 E(85289): 3.5e-10
Smith-Waterman score: 334; 26.0% identity (55.5% similar) in 411 aa overlap (4-385:8-398)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLG------YRYVAVSW-GVVVAVTGTVGNVLTLLALAIQP
:. :..: :. : . : :.:. ....:.. :: :. .:. .
XP_016 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIV--FGNGLVCMAVLKER
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLH---WRTGATFCRVFGLLLFASNSV
:.: : :...:..:::: ::..:. : ::.. : . : :: : ..
XP_016 ALQTTTNYLVVSLAVADLLVATLVMPWVV--YLEVTGGVWNFSRICCDVFVTLDVMMCTA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SILTLCLIALGRYLLIAHPKLFPQVF---SAKGIVLALVSTWVVGVASFAPLWPIYILV-
:::.:: :.. :: .. : . . : . ..: ....::.. : :: . .
XP_016 SILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTG
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 -PVVCTCSF-DRIRGRPYTTILMGIYFVLGLSSV---GIFYCLIHRQVKRAAQALDQYKL
:.::. : : . :.... ..:. .:.. . :. : .:. :: : . .
XP_016 DPTVCSISNPDFV---IYSSVV-SFYLPFGVTVLVYARIYVVLKQRRRKRI---LTRQNS
180 190 200 210 220
220 230 240 250 260 270
pF1KB8 RQASIHSNHVARTDEAMPG-----RFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSS
. :.. . .: :. :. . . : ::: :.. . .. . : .
XP_016 QCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGP--GFQER---GGELKREEKTRN
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB8 EVGDQINSKRAKQMAEKSPPEASA--KAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFAL
.. : : . .. . : . :. : :.. : .: . :.:.: :. : .
XP_016 SLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQ-PRGVPLREK---KATQMVAIVLGAFIV
290 300 310 320 330 340
340 350 360 370 380
pF1KB8 SYIPFLLLNILDARVQAPRVVHMLAANLTWL---NGCINPVLYAAMNRQFRQAYGSILKR
..::.: ..:... :. .: : . ::: :. .:::.:...: .::.:. .::
XP_016 CWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
350 360 370 380 390 400
390
pF1KB8 GPRSFHRLH
>>NP_001269492 (OMIM: 126451,181500,190300) D(3) dopamin (400 aa)
initn: 284 init1: 92 opt: 334 Z-score: 303.8 bits: 65.1 E(85289): 3.5e-10
Smith-Waterman score: 334; 26.0% identity (55.5% similar) in 411 aa overlap (4-385:8-398)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLG------YRYVAVSW-GVVVAVTGTVGNVLTLLALAIQP
:. :..: :. : . : :.:. ....:.. :: :. .:. .
NP_001 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIV--FGNGLVCMAVLKER
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLH---WRTGATFCRVFGLLLFASNSV
:.: : :...:..:::: ::..:. : ::.. : . : :: : ..
NP_001 ALQTTTNYLVVSLAVADLLVATLVMPWVV--YLEVTGGVWNFSRICCDVFVTLDVMMCTA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SILTLCLIALGRYLLIAHPKLFPQVF---SAKGIVLALVSTWVVGVASFAPLWPIYILV-
:::.:: :.. :: .. : . . : . ..: ....::.. : :: . .
NP_001 SILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTG
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 -PVVCTCSF-DRIRGRPYTTILMGIYFVLGLSSV---GIFYCLIHRQVKRAAQALDQYKL
:.::. : : . :.... ..:. .:.. . :. : .:. :: : . .
NP_001 DPTVCSISNPDFV---IYSSVV-SFYLPFGVTVLVYARIYVVLKQRRRKRI---LTRQNS
180 190 200 210 220
220 230 240 250 260 270
pF1KB8 RQASIHSNHVARTDEAMPG-----RFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSS
. :.. . .: :. :. . . : ::: :.. . .. . : .
NP_001 QCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGP--GFQER---GGELKREEKTRN
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB8 EVGDQINSKRAKQMAEKSPPEASA--KAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFAL
.. : : . .. . : . :. : :.. : .: . :.:.: :. : .
NP_001 SLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQ-PRGVPLREK---KATQMVAIVLGAFIV
290 300 310 320 330 340
340 350 360 370 380
pF1KB8 SYIPFLLLNILDARVQAPRVVHMLAANLTWL---NGCINPVLYAAMNRQFRQAYGSILKR
..::.: ..:... :. .: : . ::: :. .:::.:...: .::.:. .::
NP_001 CWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
350 360 370 380 390 400
390
pF1KB8 GPRSFHRLH
>>NP_001277738 (OMIM: 126451,181500,190300) D(3) dopamin (400 aa)
initn: 284 init1: 92 opt: 334 Z-score: 303.8 bits: 65.1 E(85289): 3.5e-10
Smith-Waterman score: 334; 26.0% identity (55.5% similar) in 411 aa overlap (4-385:8-398)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLG------YRYVAVSW-GVVVAVTGTVGNVLTLLALAIQP
:. :..: :. : . : :.:. ....:.. :: :. .:. .
NP_001 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIV--FGNGLVCMAVLKER
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLH---WRTGATFCRVFGLLLFASNSV
:.: : :...:..:::: ::..:. : ::.. : . : :: : ..
NP_001 ALQTTTNYLVVSLAVADLLVATLVMPWVV--YLEVTGGVWNFSRICCDVFVTLDVMMCTA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SILTLCLIALGRYLLIAHPKLFPQVF---SAKGIVLALVSTWVVGVASFAPLWPIYILV-
:::.:: :.. :: .. : . . : . ..: ....::.. : :: . .
NP_001 SILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTG
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 -PVVCTCSF-DRIRGRPYTTILMGIYFVLGLSSV---GIFYCLIHRQVKRAAQALDQYKL
:.::. : : . :.... ..:. .:.. . :. : .:. :: : . .
NP_001 DPTVCSISNPDFV---IYSSVV-SFYLPFGVTVLVYARIYVVLKQRRRKRI---LTRQNS
180 190 200 210 220
220 230 240 250 260 270
pF1KB8 RQASIHSNHVARTDEAMPG-----RFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSS
. :.. . .: :. :. . . : ::: :.. . .. . : .
NP_001 QCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGP--GFQER---GGELKREEKTRN
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB8 EVGDQINSKRAKQMAEKSPPEASA--KAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFAL
.. : : . .. . : . :. : :.. : .: . :.:.: :. : .
NP_001 SLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQ-PRGVPLREK---KATQMVAIVLGAFIV
290 300 310 320 330 340
340 350 360 370 380
pF1KB8 SYIPFLLLNILDARVQAPRVVHMLAANLTWL---NGCINPVLYAAMNRQFRQAYGSILKR
..::.: ..:... :. .: : . ::: :. .:::.:...: .::.:. .::
NP_001 CWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
350 360 370 380 390 400
390
pF1KB8 GPRSFHRLH
>>XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B adrene (328 aa)
initn: 300 init1: 249 opt: 297 Z-score: 273.0 bits: 59.1 E(85289): 1.8e-08
Smith-Waterman score: 297; 28.2% identity (61.7% similar) in 206 aa overlap (23-221:45-246)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLGYRYVAVSWGVVVA---VTGTVGNVLTLLALAIQP
:.: :.:.. . . :::.:..:..: .
XP_005 AHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNR
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSIL
.::: : .:.::..:::: . :::. . .: : :: ... . ..:::
XP_005 HLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASIL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB8 TLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVG-VASFAPL--WPIYILVPVVC
.:: :.. ::. . . .: . . . .:::.:.::.. : :..:: : :.
XP_005 SLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWK----EPAPN
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB8 TCSFDRIRGRPYTTILMGI-YFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSN
. . .:. ... .. : . :. . ..:: .. .::... :. ... :
XP_005 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 HVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQ
XP_005 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B adrene (331 aa)
initn: 300 init1: 249 opt: 297 Z-score: 272.9 bits: 59.1 E(85289): 1.8e-08
Smith-Waterman score: 297; 28.2% identity (61.7% similar) in 206 aa overlap (23-221:45-246)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLGYRYVAVSWGVVVA---VTGTVGNVLTLLALAIQP
:.: :.:.. . . :::.:..:..: .
XP_006 AHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNR
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSIL
.::: : .:.::..:::: . :::. . .: : :: ... . ..:::
XP_006 HLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASIL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB8 TLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVG-VASFAPL--WPIYILVPVVC
.:: :.. ::. . . .: . . . .:::.:.::.. : :..:: : :.
XP_006 SLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWK----EPAPN
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB8 TCSFDRIRGRPYTTILMGI-YFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSN
. . .:. ... .. : . :. . ..:: .. .::... :. ... :
XP_006 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 HVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQ
XP_006 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B adrene (366 aa)
initn: 300 init1: 249 opt: 297 Z-score: 272.4 bits: 59.1 E(85289): 2e-08
Smith-Waterman score: 297; 28.2% identity (61.7% similar) in 206 aa overlap (23-221:45-246)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLGYRYVAVSWGVVVA---VTGTVGNVLTLLALAIQP
:.: :.:.. . . :::.:..:..: .
XP_005 AHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNR
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSIL
.::: : .:.::..:::: . :::. . .: : :: ... . ..:::
XP_005 HLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASIL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB8 TLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVG-VASFAPL--WPIYILVPVVC
.:: :.. ::. . . .: . . . .:::.:.::.. : :..:: : :.
XP_005 SLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWK----EPAPN
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB8 TCSFDRIRGRPYTTILMGI-YFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSN
. . .:. ... .. : . :. . ..:: .. .::... :. ... :
XP_005 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 HVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQ
XP_005 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B adrene (389 aa)
initn: 300 init1: 249 opt: 297 Z-score: 272.1 bits: 59.2 E(85289): 2e-08
Smith-Waterman score: 297; 28.2% identity (61.7% similar) in 206 aa overlap (23-221:45-246)
10 20 30 40
pF1KB8 MWNSSDANFSCYHESVLGYRYVAVSWGVVVA---VTGTVGNVLTLLALAIQP
:.: :.:.. . . :::.:..:..: .
XP_011 AHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNR
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB8 KLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSIL
.::: : .:.::..:::: . :::. . .: : :: ... . ..:::
XP_011 HLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASIL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB8 TLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVG-VASFAPL--WPIYILVPVVC
.:: :.. ::. . . .: . . . .:::.:.::.. : :..:: : :.
XP_011 SLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWK----EPAPN
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB8 TCSFDRIRGRPYTTILMGI-YFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSN
. . .:. ... .. : . :. . ..:: .. .::... :. ... :
XP_011 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 HVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQ
XP_011 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
396 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:52:16 2016 done: Fri Nov 4 15:52:17 2016
Total Scan time: 7.790 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]