FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8823, 404 aa
1>>>pF1KB8823 404 - 404 aa - 404 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8586+/-0.000331; mu= 21.4069+/- 0.021
mean_var=128.8698+/-30.985, 0's: 0 Z-trim(116.6): 494 B-trim: 1326 in 1/55
Lambda= 0.112979
statistics sampled from 27202 (27856) to 27202 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.327), width: 16
Scan time: 7.410
The best scores are: opt bits E(85289)
XP_011536127 (OMIM: 605307) PREDICTED: G-protein c ( 404) 2785 465.5 1.1e-130
NP_009195 (OMIM: 605307) G-protein coupled recepto ( 404) 2785 465.5 1.1e-130
XP_011536126 (OMIM: 605307) PREDICTED: G-protein c ( 404) 2785 465.5 1.1e-130
XP_011536129 (OMIM: 605307) PREDICTED: G-protein c ( 404) 2785 465.5 1.1e-130
XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 695 124.7 3.5e-28
XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 695 124.7 3.5e-28
NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 695 124.7 3.5e-28
XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 695 124.7 3.5e-28
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 592 108.0 4.1e-23
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 526 97.2 6.8e-20
NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 521 96.4 1.2e-19
NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 521 96.4 1.2e-19
NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 521 96.4 1.3e-19
NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 521 96.4 1.3e-19
NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 521 96.4 1.3e-19
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 489 91.2 4.6e-18
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 489 91.2 4.6e-18
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 479 89.5 1.4e-17
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 479 89.5 1.4e-17
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 478 89.3 1.5e-17
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 471 88.2 3.4e-17
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 471 88.2 3.4e-17
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 470 88.0 3.8e-17
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 463 86.9 8.4e-17
NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 458 86.1 1.5e-16
XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 458 86.1 1.5e-16
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 457 85.9 1.7e-16
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 456 85.8 1.9e-16
NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 456 85.8 1.9e-16
NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 450 84.8 3.7e-16
NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 450 84.8 3.7e-16
XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 450 84.8 3.7e-16
NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 442 83.5 9.3e-16
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 440 83.2 1.2e-15
NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 439 83.0 1.3e-15
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 439 83.0 1.3e-15
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 439 83.0 1.3e-15
NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 438 82.8 1.4e-15
NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 438 82.8 1.4e-15
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 438 82.8 1.4e-15
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 438 82.8 1.4e-15
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 438 82.8 1.4e-15
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 438 82.8 1.4e-15
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 438 82.9 1.5e-15
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 438 82.9 1.5e-15
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 438 82.9 1.5e-15
>>XP_011536127 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa)
initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130
Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
310 320 330 340 350 360
370 380 390 400
pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
370 380 390 400
>>NP_009195 (OMIM: 605307) G-protein coupled receptor 18 (404 aa)
initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130
Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
310 320 330 340 350 360
370 380 390 400
pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
::::::::::::::::::::::::::::::::::::::::::::
NP_009 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
370 380 390 400
>>XP_011536126 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa)
initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130
Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
310 320 330 340 350 360
370 380 390 400
pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
370 380 390 400
>>XP_011536129 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa)
initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130
Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS
310 320 330 340 350 360
370 380 390 400
pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
370 380 390 400
>>XP_005246154 (OMIM: 610376) PREDICTED: atypical chemok (362 aa)
initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28
Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331)
30 40 50 60 70
pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN
: :.:..: :. .::.:.. : .:. ::
XP_005 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY
... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:..
XP_005 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP
.:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : .
XP_005 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR
: .: . : .. . : ... : ...::: .:: .:.:: : : . .. ...
XP_005 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV
.. .::.::..:::::::..:: . : : . :.: : :. : .:.:..::
XP_005 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA
.::.::.:.. ..: .:..: .
XP_005 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK
310 320 330 340 350 360
>>XP_016860005 (OMIM: 610376) PREDICTED: atypical chemok (362 aa)
initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28
Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331)
30 40 50 60 70
pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN
: :.:..: :. .::.:.. : .:. ::
XP_016 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY
... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:..
XP_016 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP
.:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : .
XP_016 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR
: .: . : .. . : ... : ...::: .:: .:.:: : : . .. ...
XP_016 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV
.. .::.::..:::::::..:: . : : . :.: : :. : .:.:..::
XP_016 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA
.::.::.:.. ..: .:..: .
XP_016 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK
310 320 330 340 350 360
>>NP_064707 (OMIM: 610376) atypical chemokine receptor 3 (362 aa)
initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28
Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331)
30 40 50 60 70
pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN
: :.:..: :. .::.:.. : .:. ::
NP_064 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY
... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:..
NP_064 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP
.:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : .
NP_064 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR
: .: . : .. . : ... : ...::: .:: .:.:: : : . .. ...
NP_064 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV
.. .::.::..:::::::..:: . : : . :.: : :. : .:.:..::
NP_064 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA
.::.::.:.. ..: .:..: .
NP_064 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK
310 320 330 340 350 360
>>XP_005246155 (OMIM: 610376) PREDICTED: atypical chemok (362 aa)
initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28
Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331)
30 40 50 60 70
pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN
: :.:..: :. .::.:.. : .:. ::
XP_005 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY
... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:..
XP_005 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP
.:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : .
XP_005 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR
: .: . : .. . : ... : ...::: .:: .:.:: : : . .. ...
XP_005 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV
.. .::.::..:::::::..:: . : : . :.: : :. : .:.:..::
XP_005 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA
.::.::.:.. ..: .:..: .
XP_005 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK
310 320 330 340 350 360
>>NP_001287 (OMIM: 602648) atypical chemokine receptor 2 (384 aa)
initn: 471 init1: 235 opt: 592 Z-score: 535.9 bits: 108.0 E(85289): 4.1e-23
Smith-Waterman score: 592; 32.7% identity (63.9% similar) in 330 aa overlap (43-361:36-359)
20 30 40 50 60 70
pF1KB8 EGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALYLAMFVVGLVENL
:. . : .: : ..: .::.:: ::
NP_001 SPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNL
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 LVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYF
:.. : : : ....:.::.::..: ....:: : . :. . :..::: :... .
NP_001 LLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVA--WHWVFGSFLCKMVSTL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 YFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGI-WVLSAIIPLPEVVH
: .:.::.:::. :.:.:.:. .. :.: ..: . :.. . : : :..: . .:..:
NP_001 YTINFYSGIFFISCMSLDKYLEIVHAQP-YHRLRTRAKSLLLATIVWAVSLAVSIPDMVF
130 140 150 160 170 180
200 210 220 230 240
pF1KB8 IQLVEGPEPMCLFMAPFETYST-WALAVALSTTILGFLLPFPLITVFNVLTAC---RLRQ
.: :.:. . : : ..: : : . .. ..::::::. . : .: :::
NP_001 VQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFYDVIDC
:: .. . . : :..: . :.::..::.: :: .. .:.. . : . .: .
NP_001 AGQGRALK---IAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTES
250 260 270 280 290
310 320 330 340 350 360
pF1KB8 FSMLHCVINPILYNFLSPHFRGRL---LNAVV--HYLPKD-QTKAGTCASSSSCSTQHSI
...::: ..:::: : : .:: : : ::. : : :.. ..:. :: ..:. .
NP_001 IAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEM
300 310 320 330 340 350
370 380 390 400
pF1KB8 IITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
NP_001 TGMNDLGERQSENYPNKEDVGNKSA
360 370 380
>>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa)
initn: 436 init1: 335 opt: 526 Z-score: 478.1 bits: 97.2 E(85289): 6.8e-20
Smith-Waterman score: 526; 28.1% identity (62.1% similar) in 335 aa overlap (34-360:19-345)
10 20 30 40 50 60
pF1KB8 KPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALYLAM
:.:. : : .:: :.. ...: ..: .
NP_005 MDYTLDLSVTTVTDYYYPDIFS---SPCDAELIQTNGKLLLAVFYCLL
10 20 30 40
70 80 90 100 110 120
pF1KB8 FVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGS
:: .:. : ::: : . .. ..:.::.:..:: .:.:.: .. :: :..:.
NP_005 FVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFP-FQTYYLLDQ-WVFGT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 FSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAI
:. . ::....:::.::.. .:::::.... : . . :. ..: ..:. . .
NP_005 VMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIM
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IPLPEVVHIQLV-EGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTA
.: .: :.. : .: . .: . : . . .. .:::.:.:: .. .
NP_005 ATIPLLVFYQVASEDGVLQCYSFYNQQTLK-WKIFTNFKMNILGLLIPFTIFMFCYIKIL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 CRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFY
.:.. . .. . :. : . .. :.:..:.:.: .::. :: : . . : .
NP_005 HQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYAT
230 240 250 260 270 280
310 320 330 340 350
pF1KB8 DVIDCFSMLHCVINPILYNFLSPHFRGRL-------LNAVVHYLPKDQTKAGTCASSSSC
: . .:. :: .::..: :.. .:. .: . . .:: ... . .: .::::
NP_005 HVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRE-SCEKSSSC
290 300 310 320 330 340
360 370 380 390 400
pF1KB8 STQHSIIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
. :::
NP_005 Q-QHSSRSSSVDYIL
350
404 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:53:24 2016 done: Fri Nov 4 15:53:25 2016
Total Scan time: 7.410 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]