FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8823, 404 aa 1>>>pF1KB8823 404 - 404 aa - 404 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8586+/-0.000331; mu= 21.4069+/- 0.021 mean_var=128.8698+/-30.985, 0's: 0 Z-trim(116.6): 494 B-trim: 1326 in 1/55 Lambda= 0.112979 statistics sampled from 27202 (27856) to 27202 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.327), width: 16 Scan time: 7.410 The best scores are: opt bits E(85289) XP_011536127 (OMIM: 605307) PREDICTED: G-protein c ( 404) 2785 465.5 1.1e-130 NP_009195 (OMIM: 605307) G-protein coupled recepto ( 404) 2785 465.5 1.1e-130 XP_011536126 (OMIM: 605307) PREDICTED: G-protein c ( 404) 2785 465.5 1.1e-130 XP_011536129 (OMIM: 605307) PREDICTED: G-protein c ( 404) 2785 465.5 1.1e-130 XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 695 124.7 3.5e-28 XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 695 124.7 3.5e-28 NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 695 124.7 3.5e-28 XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 695 124.7 3.5e-28 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 592 108.0 4.1e-23 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 526 97.2 6.8e-20 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 521 96.4 1.2e-19 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 521 96.4 1.2e-19 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 521 96.4 1.3e-19 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 521 96.4 1.3e-19 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 521 96.4 1.3e-19 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 489 91.2 4.6e-18 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 489 91.2 4.6e-18 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 479 89.5 1.4e-17 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 479 89.5 1.4e-17 NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 478 89.3 1.5e-17 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 471 88.2 3.4e-17 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 471 88.2 3.4e-17 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 471 88.2 3.4e-17 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 470 88.0 3.8e-17 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 463 86.9 8.4e-17 NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 458 86.1 1.5e-16 XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 458 86.1 1.5e-16 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 457 85.9 1.7e-16 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 456 85.8 1.9e-16 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 456 85.8 1.9e-16 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 450 84.8 3.7e-16 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 450 84.8 3.7e-16 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 450 84.8 3.7e-16 NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 442 83.5 9.3e-16 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 440 83.2 1.2e-15 NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 439 83.0 1.3e-15 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 439 83.0 1.3e-15 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 439 83.0 1.3e-15 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 438 82.8 1.4e-15 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 438 82.8 1.4e-15 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 438 82.8 1.4e-15 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 438 82.8 1.4e-15 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 438 82.8 1.4e-15 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 438 82.8 1.4e-15 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 438 82.9 1.5e-15 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 438 82.9 1.5e-15 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 438 82.9 1.5e-15 >>XP_011536127 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa) initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130 Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS 310 320 330 340 350 360 370 380 390 400 pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS :::::::::::::::::::::::::::::::::::::::::::: XP_011 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS 370 380 390 400 >>NP_009195 (OMIM: 605307) G-protein coupled receptor 18 (404 aa) initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130 Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS 310 320 330 340 350 360 370 380 390 400 pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS :::::::::::::::::::::::::::::::::::::::::::: NP_009 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS 370 380 390 400 >>XP_011536126 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa) initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130 Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS 310 320 330 340 350 360 370 380 390 400 pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS :::::::::::::::::::::::::::::::::::::::::::: XP_011 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS 370 380 390 400 >>XP_011536129 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa) initn: 2785 init1: 2785 opt: 2785 Z-score: 2467.5 bits: 465.5 E(85289): 1.1e-130 Smith-Waterman score: 2785; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB8 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHS 310 320 330 340 350 360 370 380 390 400 pF1KB8 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS :::::::::::::::::::::::::::::::::::::::::::: XP_011 IIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS 370 380 390 400 >>XP_005246154 (OMIM: 610376) PREDICTED: atypical chemok (362 aa) initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331) 30 40 50 60 70 pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN : :.:..: :. .::.:.. : .:. :: XP_005 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. XP_005 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . XP_005 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... XP_005 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: XP_005 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA .::.::.:.. ..: .:..: . XP_005 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK 310 320 330 340 350 360 >>XP_016860005 (OMIM: 610376) PREDICTED: atypical chemok (362 aa) initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331) 30 40 50 60 70 pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN : :.:..: :. .::.:.. : .:. :: XP_016 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. XP_016 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . XP_016 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... XP_016 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: XP_016 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA .::.::.:.. ..: .:..: . XP_016 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK 310 320 330 340 350 360 >>NP_064707 (OMIM: 610376) atypical chemokine receptor 3 (362 aa) initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331) 30 40 50 60 70 pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN : :.:..: :. .::.:.. : .:. :: NP_064 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. NP_064 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . NP_064 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... NP_064 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: NP_064 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA .::.::.:.. ..: .:..: . NP_064 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK 310 320 330 340 350 360 >>XP_005246155 (OMIM: 610376) PREDICTED: atypical chemok (362 aa) initn: 636 init1: 362 opt: 695 Z-score: 626.9 bits: 124.7 E(85289): 3.5e-28 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (52-336:40-331) 30 40 50 60 70 pF1KB8 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN : :.:..: :. .::.:.. : .:. :: XP_005 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. XP_005 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . XP_005 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB8 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... XP_005 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB8 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: XP_005 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB8 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA .::.::.:.. ..: .:..: . XP_005 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK 310 320 330 340 350 360 >>NP_001287 (OMIM: 602648) atypical chemokine receptor 2 (384 aa) initn: 471 init1: 235 opt: 592 Z-score: 535.9 bits: 108.0 E(85289): 4.1e-23 Smith-Waterman score: 592; 32.7% identity (63.9% similar) in 330 aa overlap (43-361:36-359) 20 30 40 50 60 70 pF1KB8 EGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALYLAMFVVGLVENL :. . : .: : ..: .::.:: :: NP_001 SPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNL 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 LVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYF :.. : : : ....:.::.::..: ....:: : . :. . :..::: :... . NP_001 LLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVA--WHWVFGSFLCKMVSTL 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 YFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGI-WVLSAIIPLPEVVH : .:.::.:::. :.:.:.:. .. :.: ..: . :.. . : : :..: . .:..: NP_001 YTINFYSGIFFISCMSLDKYLEIVHAQP-YHRLRTRAKSLLLATIVWAVSLAVSIPDMVF 130 140 150 160 170 180 200 210 220 230 240 pF1KB8 IQLVEGPEPMCLFMAPFETYST-WALAVALSTTILGFLLPFPLITVFNVLTAC---RLRQ .: :.:. . : : ..: : : . .. ..::::::. . : .: ::: NP_001 VQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFYDVIDC :: .. . . : :..: . :.::..::.: :: .. .:.. . : . .: . NP_001 AGQGRALK---IAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTES 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 FSMLHCVINPILYNFLSPHFRGRL---LNAVV--HYLPKD-QTKAGTCASSSSCSTQHSI ...::: ..:::: : : .:: : : ::. : : :.. ..:. :: ..:. . NP_001 IAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEM 300 310 320 330 340 350 370 380 390 400 pF1KB8 IITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS NP_001 TGMNDLGERQSENYPNKEDVGNKSA 360 370 380 >>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa) initn: 436 init1: 335 opt: 526 Z-score: 478.1 bits: 97.2 E(85289): 6.8e-20 Smith-Waterman score: 526; 28.1% identity (62.1% similar) in 335 aa overlap (34-360:19-345) 10 20 30 40 50 60 pF1KB8 KPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALYLAM :.:. : : .:: :.. ...: ..: . NP_005 MDYTLDLSVTTVTDYYYPDIFS---SPCDAELIQTNGKLLLAVFYCLL 10 20 30 40 70 80 90 100 110 120 pF1KB8 FVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGS :: .:. : ::: : . .. ..:.::.:..:: .:.:.: .. :: :..:. NP_005 FVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFP-FQTYYLLDQ-WVFGT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 FSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAI :. . ::....:::.::.. .:::::.... : . . :. ..: ..:. . . NP_005 VMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIM 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 IPLPEVVHIQLV-EGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTA .: .: :.. : .: . .: . : . . .. .:::.:.:: .. . NP_005 ATIPLLVFYQVASEDGVLQCYSFYNQQTLK-WKIFTNFKMNILGLLIPFTIFMFCYIKIL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 CRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFY .:.. . .. . :. : . .. :.:..:.:.: .::. :: : . . : . NP_005 HQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYAT 230 240 250 260 270 280 310 320 330 340 350 pF1KB8 DVIDCFSMLHCVINPILYNFLSPHFRGRL-------LNAVVHYLPKDQTKAGTCASSSSC : . .:. :: .::..: :.. .:. .: . . .:: ... . .: .:::: NP_005 HVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRE-SCEKSSSC 290 300 310 320 330 340 360 370 380 390 400 pF1KB8 STQHSIIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS . ::: NP_005 Q-QHSSRSSSVDYIL 350 404 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:53:24 2016 done: Fri Nov 4 15:53:25 2016 Total Scan time: 7.410 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]