FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8830, 440 aa 1>>>pF1KB8830 440 - 440 aa - 440 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3871+/-0.000969; mu= 11.7788+/- 0.058 mean_var=85.6176+/-17.020, 0's: 0 Z-trim(106.1): 46 B-trim: 0 in 0/49 Lambda= 0.138609 statistics sampled from 8778 (8809) to 8778 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.271), width: 16 Scan time: 2.830 The best scores are: opt bits E(32554) CCDS9722.1 SOCS4 gene_id:122809|Hs108|chr14 ( 440) 3048 619.7 1.8e-177 CCDS1830.1 SOCS5 gene_id:9655|Hs108|chr2 ( 536) 1160 242.2 9.8e-64 >>CCDS9722.1 SOCS4 gene_id:122809|Hs108|chr14 (440 aa) initn: 3048 init1: 3048 opt: 3048 Z-score: 3299.5 bits: 619.7 E(32554): 1.8e-177 Smith-Waterman score: 3048; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440) 10 20 30 40 50 60 pF1KB8 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK 370 380 390 400 410 420 430 440 pF1KB8 EYHYKSKVRVLRIDAPEQQC :::::::::::::::::::: CCDS97 EYHYKSKVRVLRIDAPEQQC 430 440 >>CCDS1830.1 SOCS5 gene_id:9655|Hs108|chr2 (536 aa) initn: 1399 init1: 1035 opt: 1160 Z-score: 1257.7 bits: 242.2 E(32554): 9.8e-64 Smith-Waterman score: 1496; 54.2% identity (77.3% similar) in 437 aa overlap (7-430:93-525) 10 20 30 pF1KB8 MAENNENISKNVD--VRPKTSRSRSADRKDGYVWSG .: :. : : : : .: . . :.: CCDS18 IALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGG 70 80 90 100 110 120 40 50 60 70 80 90 pF1KB8 KKL-SWSKKSESYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCGHRFLG-RSLK :: : : :..: ::. : .:. .:. .::... ::.. :.: : . : .: :::. CCDS18 KKKHSCSTKTQSSLDADKKFG--RTRSGLQRRERRYGVSSVH-DMD-SVSSRTVGSRSLR 130 140 150 160 170 100 110 120 130 140 150 pF1KB8 QKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTA :.:::.:: :::... :.. . . .:::::.:::::.::::: :::: .::.::.::: CCDS18 QRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTA 180 190 200 210 220 230 160 170 180 190 200 pF1KB8 PINSKSDEWVSTD--LSQTELRDGQLKRR---NMEENINCFSHTNVQPCVITTD-NALCR :.. .: . . : : .:: .. .:..: ..::... ..... :.. : : . CCDS18 PVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYK 240 250 260 270 280 290 210 220 230 240 250 260 pF1KB8 EGPMTGSVMNLVSNNS--IEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEI-LQLETPPK :: . :. .:..: : ... ::... ::: .::.... . . :.. .. . : CCDS18 LGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWK 300 310 320 330 340 350 270 280 290 300 310 320 pF1KB8 YHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVS ::::::.::::::::::..:::::::::.: :::::::::::::::::::::::::::: CCDS18 VHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVS 360 370 380 390 400 410 330 340 350 360 370 380 pF1KB8 FRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIR ::::.:::::::::::::::::::::::::: .:::::::::::.::::::::. : : CCDS18 FRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNR 420 430 440 450 460 470 390 400 410 420 430 440 pF1KB8 TFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC :::::::.:::.::: ::::::::.::.:: .. .:::::::.:::: CCDS18 TFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK 480 490 500 510 520 530 440 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:55:09 2016 done: Fri Nov 4 15:55:09 2016 Total Scan time: 2.830 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]