FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8838, 463 aa 1>>>pF1KB8838 463 - 463 aa - 463 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7543+/-0.000833; mu= 15.2002+/- 0.050 mean_var=76.3766+/-15.556, 0's: 0 Z-trim(107.7): 37 B-trim: 68 in 1/50 Lambda= 0.146755 statistics sampled from 9710 (9735) to 9710 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.299), width: 16 Scan time: 3.000 The best scores are: opt bits E(32554) CCDS14610.1 DCAF12L1 gene_id:139170|Hs108|chrX ( 463) 3171 681.0 7.1e-196 CCDS43991.1 DCAF12L2 gene_id:340578|Hs108|chrX ( 463) 2778 597.8 8e-171 CCDS6549.1 DCAF12 gene_id:25853|Hs108|chr9 ( 453) 1843 399.8 3.1e-111 >>CCDS14610.1 DCAF12L1 gene_id:139170|Hs108|chrX (463 aa) initn: 3171 init1: 3171 opt: 3171 Z-score: 3630.0 bits: 681.0 E(32554): 7.1e-196 Smith-Waterman score: 3171; 99.8% identity (99.8% similar) in 463 aa overlap (1-463:1-463) 10 20 30 40 50 60 pF1KB8 MAQQQTGSRKRKAPAVEAGAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: CCDS14 MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY 370 380 390 400 410 420 430 440 450 460 pF1KB8 FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS ::::::::::::::::::::::::::::::::::::::::::: CCDS14 FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS 430 440 450 460 >>CCDS43991.1 DCAF12L2 gene_id:340578|Hs108|chrX (463 aa) initn: 2778 init1: 2778 opt: 2778 Z-score: 3180.3 bits: 597.8 E(32554): 8e-171 Smith-Waterman score: 2778; 87.0% identity (94.6% similar) in 463 aa overlap (1-463:1-463) 10 20 30 40 50 60 pF1KB8 MAQQQTGSRKRKAPAVEAGAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREV :::::::::::::::::::: :: :::::::::::::: :.:.:::: : ..:::: ::: CCDS43 MAQQQTGSRKRKAPAVEAGAGSSSSQGLAAADGEGPLLPKKQKRPATRRRLVHYLKGREV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTL :. ::: ::::.::::::::::::::::::::.:::.::::::::::.:::::::::::: CCDS43 GARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP :::::.::::.::::.::.:: ::: .::::::::::::::::::::::::::::::::: CCDS43 FVVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLP .:::::::::::::::::::::::::::::::::::::::::::: :. ..::::::::: CCDS43 TLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIAWHSEVGLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLS :::::::::::::::: ::::::::::: .:::::::::::::::::::: :.:::::: CCDS43 VYAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 IRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYR ::::: :.::::::::..:.:::::.::::::: :: ::::::::::::::::::::::. CCDS43 IRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 HIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNY ::::::::.:::::::.:::::::::::..:.: ::: :::.:::::::::..: :::: CCDS43 HIITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNY 370 380 390 400 410 420 430 440 450 460 pF1KB8 FGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS :::: :::::::::::::::::::::::::.::::::::::: CCDS43 FGGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS 430 440 450 460 >>CCDS6549.1 DCAF12 gene_id:25853|Hs108|chr9 (453 aa) initn: 1871 init1: 1197 opt: 1843 Z-score: 2110.6 bits: 399.8 E(32554): 3.1e-111 Smith-Waterman score: 1860; 61.3% identity (80.4% similar) in 465 aa overlap (8-463:7-453) 10 20 30 40 50 pF1KB8 MAQQQTGSRKRKAPAVEAGAESSPSQGLAAADGEGPL------LLKRQRRPATYRSMAHY :::::::: ::. : .:..:: : ::.: : . ::...: CCDS65 MARKVVSRKRKAPA-------SPGAG---SDAQGPQFGWDHSLHKRKRLPPVKRSLVYY 10 20 30 40 60 70 80 90 100 110 pF1KB8 LKVREVGGWGPARLQG---FDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQV :: ::: :::. .. :.:::.:.:: :: ::...:::.:::::::::: ::: CCDS65 LKNREV------RLQNETSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQV 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 VCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENP ::::::::::::::....:..::.:.: : . ::::::::::::::.:::::::.:: CCDS65 VCGTKCNTLFVVDVQTSQITKIPILKDREPG-GVTQQGCGIHAIELNPSRTLLATGGDNP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 NSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTV ::::::.::.:::.:.:: :::::::..::.:::.::::::::...::.. : . . CCDS65 NSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSD 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 AWHSEVGLPVYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKA : :. .:::::: . .. ::. ::.: :::::: ..::.:::::::::::::::: CCDS65 ARHNVSRVPVYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKA 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 GSALSRLLSIRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGT ..::.::: .::: :.::::.: .. :::::::..:::::: :: . :.. .:::: :. CCDS65 ENTLSKLLSTKLPYCRENVCLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGS 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 GVRSLSFYRHIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWL :.::.:::.::::::::::::::::.:::.::::: :: :. : ..:.:. :.::: CCDS65 GIRSVSFYEHIITVGTGQGSLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWL 350 360 370 380 390 400 420 430 440 450 460 pF1KB8 NHNDFWVNYFGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS ::.. : :::. .. ::::.:::::. ::::::::::.::::::::::: CCDS65 NHDETWRNYFSDIDFFPNAVYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS 410 420 430 440 450 463 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:00:20 2016 done: Fri Nov 4 16:00:21 2016 Total Scan time: 3.000 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]