FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8851, 73 aa 1>>>pF1KB8851 73 - 73 aa - 73 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7955+/-0.000235; mu= 6.7961+/- 0.015 mean_var=88.8522+/-17.669, 0's: 0 Z-trim(123.5): 31 B-trim: 84 in 1/54 Lambda= 0.136063 statistics sampled from 43311 (43342) to 43311 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.853), E-opt: 0.2 (0.508), width: 16 Scan time: 4.200 The best scores are: opt bits E(85289) NP_004117 (OMIM: 604390) guanine nucleotide-bindin ( 73) 481 102.4 6.8e-23 NP_001316355 (OMIM: 189970) guanine nucleotide-bin ( 74) 380 82.6 6.4e-17 NP_068774 (OMIM: 189970) guanine nucleotide-bindin ( 74) 380 82.6 6.4e-17 NP_001185685 (OMIM: 139391) guanine nucleotide-bin ( 69) 299 66.6 3.7e-12 NP_001185684 (OMIM: 139391) guanine nucleotide-bin ( 69) 299 66.6 3.7e-12 NP_113686 (OMIM: 139391) guanine nucleotide-bindin ( 69) 299 66.6 3.7e-12 NP_001185683 (OMIM: 139391) guanine nucleotide-bin ( 69) 299 66.6 3.7e-12 XP_016857299 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 181 43.5 3.6e-05 NP_061329 (OMIM: 615405) guanine nucleotide-bindin ( 72) 181 43.5 3.6e-05 XP_016857300 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 181 43.5 3.6e-05 XP_016857298 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 181 43.5 3.6e-05 XP_016882095 (OMIM: 604430) PREDICTED: guanine nuc ( 68) 172 41.7 0.00012 NP_443079 (OMIM: 604430) guanine nucleotide-bindin ( 68) 172 41.7 0.00012 NP_444292 (OMIM: 606981) guanine nucleotide-bindin ( 71) 146 36.6 0.0042 XP_016876866 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 146 36.6 0.0042 NP_001230703 (OMIM: 606981) guanine nucleotide-bin ( 71) 146 36.6 0.0042 XP_011535148 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 146 36.6 0.0042 NP_001230702 (OMIM: 606981) guanine nucleotide-bin ( 71) 146 36.6 0.0042 XP_016876865 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 146 36.6 0.0042 XP_006720236 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 146 36.6 0.0042 XP_006718563 (OMIM: 608941) PREDICTED: guanine nuc ( 75) 144 36.2 0.0057 NP_036334 (OMIM: 608941) guanine nucleotide-bindin ( 75) 144 36.2 0.0057 NP_001017998 (OMIM: 604389) guanine nucleotide-bin ( 68) 143 36.0 0.0061 NP_001185593 (OMIM: 604389) guanine nucleotide-bin ( 68) 143 36.0 0.0061 >>NP_004117 (OMIM: 604390) guanine nucleotide-binding pr (73 aa) initn: 481 init1: 481 opt: 481 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 481; 100.0% identity (100.0% similar) in 73 aa overlap (1-73:1-73) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED 10 20 30 40 50 60 70 pF1KB8 KNPFKEKGSCVIS ::::::::::::: NP_004 KNPFKEKGSCVIS 70 >>NP_001316355 (OMIM: 189970) guanine nucleotide-binding (74 aa) initn: 378 init1: 350 opt: 380 Z-score: 424.7 bits: 82.6 E(85289): 6.4e-17 Smith-Waterman score: 380; 75.7% identity (93.2% similar) in 74 aa overlap (1-73:1-74) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED ::...:::: ::.::::::.::.::: :.:. :::: ::...:.:::::::::::::::: NP_001 MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPED 10 20 30 40 50 60 70 pF1KB8 KNPFKE-KGSCVIS :::::: ::.:::: NP_001 KNPFKELKGGCVIS 70 >>NP_068774 (OMIM: 189970) guanine nucleotide-binding pr (74 aa) initn: 378 init1: 350 opt: 380 Z-score: 424.7 bits: 82.6 E(85289): 6.4e-17 Smith-Waterman score: 380; 75.7% identity (93.2% similar) in 74 aa overlap (1-73:1-74) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED ::...:::: ::.::::::.::.::: :.:. :::: ::...:.:::::::::::::::: NP_068 MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPED 10 20 30 40 50 60 70 pF1KB8 KNPFKE-KGSCVIS :::::: ::.:::: NP_068 KNPFKELKGGCVIS 70 >>NP_001185685 (OMIM: 139391) guanine nucleotide-binding (69 aa) initn: 299 init1: 299 opt: 299 Z-score: 339.2 bits: 66.6 E(85289): 3.7e-12 Smith-Waterman score: 299; 65.7% identity (88.1% similar) in 67 aa overlap (7-73:3-69) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED .:: ::. ::::::::.:::: : .:: ..:::.:.: ..:.::..:::::: NP_001 MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPED 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS ::::::::.:.:: NP_001 KNPFKEKGGCLIS 60 >>NP_001185684 (OMIM: 139391) guanine nucleotide-binding (69 aa) initn: 299 init1: 299 opt: 299 Z-score: 339.2 bits: 66.6 E(85289): 3.7e-12 Smith-Waterman score: 299; 65.7% identity (88.1% similar) in 67 aa overlap (7-73:3-69) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED .:: ::. ::::::::.:::: : .:: ..:::.:.: ..:.::..:::::: NP_001 MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPED 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS ::::::::.:.:: NP_001 KNPFKEKGGCLIS 60 >>NP_113686 (OMIM: 139391) guanine nucleotide-binding pr (69 aa) initn: 299 init1: 299 opt: 299 Z-score: 339.2 bits: 66.6 E(85289): 3.7e-12 Smith-Waterman score: 299; 65.7% identity (88.1% similar) in 67 aa overlap (7-73:3-69) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED .:: ::. ::::::::.:::: : .:: ..:::.:.: ..:.::..:::::: NP_113 MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPED 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS ::::::::.:.:: NP_113 KNPFKEKGGCLIS 60 >>NP_001185683 (OMIM: 139391) guanine nucleotide-binding (69 aa) initn: 299 init1: 299 opt: 299 Z-score: 339.2 bits: 66.6 E(85289): 3.7e-12 Smith-Waterman score: 299; 65.7% identity (88.1% similar) in 67 aa overlap (7-73:3-69) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED .:: ::. ::::::::.:::: : .:: ..:::.:.: ..:.::..:::::: NP_001 MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPED 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS ::::::::.:.:: NP_001 KNPFKEKGGCLIS 60 >>XP_016857299 (OMIM: 615405) PREDICTED: guanine nucleot (72 aa) initn: 174 init1: 174 opt: 181 Z-score: 213.8 bits: 43.5 E(85289): 3.6e-05 Smith-Waterman score: 181; 48.1% identity (79.6% similar) in 54 aa overlap (19-72:18-71) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED :.::: :....: .::: : .. .: ::.. :::. ::: . XP_016 MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTS 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS .::::.: .:.: XP_016 ENPFKDKKTCIIL 60 70 >>NP_061329 (OMIM: 615405) guanine nucleotide-binding pr (72 aa) initn: 174 init1: 174 opt: 181 Z-score: 213.8 bits: 43.5 E(85289): 3.6e-05 Smith-Waterman score: 181; 48.1% identity (79.6% similar) in 54 aa overlap (19-72:18-71) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED :.::: :....: .::: : .. .: ::.. :::. ::: . NP_061 MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTS 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS .::::.: .:.: NP_061 ENPFKDKKTCIIL 60 70 >>XP_016857300 (OMIM: 615405) PREDICTED: guanine nucleot (72 aa) initn: 174 init1: 174 opt: 181 Z-score: 213.8 bits: 43.5 E(85289): 3.6e-05 Smith-Waterman score: 181; 48.1% identity (79.6% similar) in 54 aa overlap (19-72:18-71) 10 20 30 40 50 60 pF1KB8 MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPED :.::: :....: .::: : .. .: ::.. :::. ::: . XP_016 MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTS 10 20 30 40 50 70 pF1KB8 KNPFKEKGSCVIS .::::.: .:.: XP_016 ENPFKDKKTCIIL 60 70 73 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:12:15 2016 done: Sat Nov 5 20:12:16 2016 Total Scan time: 4.200 Total Display time: -0.050 Function used was FASTA [36.3.4 Apr, 2011]