FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8852, 75 aa 1>>>pF1KB8852 75 - 75 aa - 75 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7516+/-0.000262; mu= 9.9087+/- 0.016 mean_var=49.1813+/- 9.563, 0's: 0 Z-trim(119.3): 76 B-trim: 0 in 0/51 Lambda= 0.182883 statistics sampled from 33077 (33158) to 33077 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.389), width: 16 Scan time: 3.780 The best scores are: opt bits E(85289) XP_006718563 (OMIM: 608941) PREDICTED: guanine nuc ( 75) 499 138.3 1.1e-33 NP_036334 (OMIM: 608941) guanine nucleotide-bindin ( 75) 499 138.3 1.1e-33 XP_016876865 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 363 102.4 6.8e-23 NP_001230703 (OMIM: 606981) guanine nucleotide-bin ( 71) 363 102.4 6.8e-23 XP_011535148 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 363 102.4 6.8e-23 NP_444292 (OMIM: 606981) guanine nucleotide-bindin ( 71) 363 102.4 6.8e-23 XP_016876866 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 363 102.4 6.8e-23 NP_001230702 (OMIM: 606981) guanine nucleotide-bin ( 71) 363 102.4 6.8e-23 XP_006720236 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 363 102.4 6.8e-23 XP_011542469 (OMIM: 604388) PREDICTED: guanine nuc ( 75) 341 96.6 4e-21 NP_001092191 (OMIM: 604388) guanine nucleotide-bin ( 75) 341 96.6 4e-21 NP_004476 (OMIM: 604388) guanine nucleotide-bindin ( 75) 341 96.6 4e-21 XP_006711824 (OMIM: 604388) PREDICTED: guanine nuc ( 75) 341 96.6 4e-21 NP_001092192 (OMIM: 604388) guanine nucleotide-bin ( 75) 341 96.6 4e-21 XP_016882095 (OMIM: 604430) PREDICTED: guanine nuc ( 68) 275 79.2 6.4e-16 NP_443079 (OMIM: 604430) guanine nucleotide-bindin ( 68) 275 79.2 6.4e-16 XP_016857299 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 272 78.4 1.2e-15 XP_016857298 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 272 78.4 1.2e-15 XP_016857300 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 272 78.4 1.2e-15 NP_061329 (OMIM: 615405) guanine nucleotide-bindin ( 72) 272 78.4 1.2e-15 NP_001017998 (OMIM: 604389) guanine nucleotide-bin ( 68) 218 64.1 2.2e-11 NP_001185593 (OMIM: 604389) guanine nucleotide-bin ( 68) 218 64.1 2.2e-11 NP_005265 (OMIM: 600874) guanine nucleotide-bindin ( 68) 210 62.0 9.3e-11 NP_001185684 (OMIM: 139391) guanine nucleotide-bin ( 69) 148 45.7 7.9e-06 NP_001185685 (OMIM: 139391) guanine nucleotide-bin ( 69) 148 45.7 7.9e-06 NP_113686 (OMIM: 139391) guanine nucleotide-bindin ( 69) 148 45.7 7.9e-06 NP_001185683 (OMIM: 139391) guanine nucleotide-bin ( 69) 148 45.7 7.9e-06 NP_068774 (OMIM: 189970) guanine nucleotide-bindin ( 74) 147 45.4 1e-05 NP_001316355 (OMIM: 189970) guanine nucleotide-bin ( 74) 147 45.4 1e-05 NP_004117 (OMIM: 604390) guanine nucleotide-bindin ( 73) 144 44.6 1.7e-05 >>XP_006718563 (OMIM: 608941) PREDICTED: guanine nucleot (75 aa) initn: 499 init1: 499 opt: 499 Z-score: 725.5 bits: 138.3 E(85289): 1.1e-33 Smith-Waterman score: 499; 100.0% identity (100.0% similar) in 75 aa overlap (1-75:1-75) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT 10 20 30 40 50 60 70 pF1KB8 SENPFREKKFFCALL ::::::::::::::: XP_006 SENPFREKKFFCALL 70 >>NP_036334 (OMIM: 608941) guanine nucleotide-binding pr (75 aa) initn: 499 init1: 499 opt: 499 Z-score: 725.5 bits: 138.3 E(85289): 1.1e-33 Smith-Waterman score: 499; 100.0% identity (100.0% similar) in 75 aa overlap (1-75:1-75) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT 10 20 30 40 50 60 70 pF1KB8 SENPFREKKFFCALL ::::::::::::::: NP_036 SENPFREKKFFCALL 70 >>XP_016876865 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. XP_016 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: XP_016 SENPFREKKFFCAIL 60 70 >>NP_001230703 (OMIM: 606981) guanine nucleotide-binding (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. NP_001 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: NP_001 SENPFREKKFFCAIL 60 70 >>XP_011535148 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. XP_011 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: XP_011 SENPFREKKFFCAIL 60 70 >>NP_444292 (OMIM: 606981) guanine nucleotide-binding pr (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. NP_444 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: NP_444 SENPFREKKFFCAIL 60 70 >>XP_016876866 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. XP_016 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: XP_016 SENPFREKKFFCAIL 60 70 >>NP_001230702 (OMIM: 606981) guanine nucleotide-binding (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. NP_001 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: NP_001 SENPFREKKFFCAIL 60 70 >>XP_006720236 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 358 init1: 351 opt: 363 Z-score: 532.0 bits: 102.4 E(85289): 6.8e-23 Smith-Waterman score: 363; 79.4% identity (95.6% similar) in 68 aa overlap (8-75:4-71) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :.: ::.::::.:::::.::.. ::::::::::::.::.::: ::::.::::. XP_006 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPA 10 20 30 40 50 70 pF1KB8 SENPFREKKFFCALL :::::::::::::.: XP_006 SENPFREKKFFCAIL 60 70 >>XP_011542469 (OMIM: 604388) PREDICTED: guanine nucleot (75 aa) initn: 351 init1: 341 opt: 341 Z-score: 500.2 bits: 96.6 E(85289): 4e-21 Smith-Waterman score: 341; 69.3% identity (85.3% similar) in 75 aa overlap (1-75:1-75) 10 20 30 40 50 60 pF1KB8 MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT :: ::: ::.:::: :::::.:: . :.:::.:::::..::.::. ::::: :::. XP_011 MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 10 20 30 40 50 60 70 pF1KB8 SENPFREKKFFCALL ::::::::::::..: XP_011 SENPFREKKFFCTIL 70 75 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:56:19 2016 done: Sat Nov 5 19:56:20 2016 Total Scan time: 3.780 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]