FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8856, 90 aa 1>>>pF1KB8856 90 - 90 aa - 90 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7748+/-0.000699; mu= 6.1570+/- 0.042 mean_var=66.3032+/-12.919, 0's: 0 Z-trim(109.6): 43 B-trim: 0 in 0/51 Lambda= 0.157510 statistics sampled from 10990 (11033) to 10990 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.339), width: 16 Scan time: 1.450 The best scores are: opt bits E(32554) CCDS1040.1 S100A6 gene_id:6277|Hs108|chr1 ( 90) 571 137.8 8.5e-34 CCDS1042.1 S100A4 gene_id:6275|Hs108|chr1 ( 101) 318 80.4 1.9e-16 CCDS1041.2 S100A5 gene_id:6276|Hs108|chr1 ( 92) 304 77.2 1.6e-15 CCDS1044.1 S100A2 gene_id:6273|Hs108|chr1 ( 97) 273 70.1 2.2e-13 CCDS1047.1 S100A1 gene_id:6271|Hs108|chr1 ( 94) 245 63.8 1.8e-11 CCDS1043.1 S100A3 gene_id:6274|Hs108|chr1 ( 101) 236 61.7 7.8e-11 >>CCDS1040.1 S100A6 gene_id:6277|Hs108|chr1 (90 aa) initn: 571 init1: 571 opt: 571 Z-score: 720.2 bits: 137.8 E(32554): 8.5e-34 Smith-Waterman score: 571; 100.0% identity (100.0% similar) in 90 aa overlap (1-90:1-90) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL 10 20 30 40 50 60 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :::::::::::::::::::::::::::::: CCDS10 DRNKDQEVNFQEYVTFLGALALIYNEALKG 70 80 90 >>CCDS1042.1 S100A4 gene_id:6275|Hs108|chr1 (101 aa) initn: 299 init1: 188 opt: 318 Z-score: 408.7 bits: 80.4 E(32554): 1.9e-16 Smith-Waterman score: 318; 50.0% identity (81.5% similar) in 92 aa overlap (1-90:1-92) 10 20 30 40 50 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELT--IGSKLQDAEIARLME :::::..:. ..:. ::::::.:::: :.:.:::::. .:: .:.. ..: . .:: CCDS10 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG .:: :.:.::.:::: .::. .:.. :: ..: CCDS10 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK 70 80 90 100 >>CCDS1041.2 S100A5 gene_id:6276|Hs108|chr1 (92 aa) initn: 299 init1: 184 opt: 304 Z-score: 392.1 bits: 77.2 E(32554): 1.6e-15 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:1-85) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL : ::..:. .:. :::::::::.: :::.:::::::.::: .: ..... : ::..: CCDS10 METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLG-EMKESSIDDLMKSL 10 20 30 40 50 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :.:.:::..:.:: .:: : . ::. CCDS10 DKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 60 70 80 90 >>CCDS1044.1 S100A2 gene_id:6273|Hs108|chr1 (97 aa) initn: 254 init1: 156 opt: 273 Z-score: 353.7 bits: 70.1 E(32554): 2.2e-13 Smith-Waterman score: 273; 46.7% identity (79.3% similar) in 92 aa overlap (1-90:1-92) 10 20 30 40 50 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELT--IGSKLQDAEIARLME : :.::...::. ::::: .:::: ::: :.:::..::: .: :... . .:: CCDS10 MCSSLEQALAVLVTTFHKYSCQEGDKFKLSKGEMKELLHKELPSFVGEKVDEEGLKKLMG 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG .::.:.::.:.::::..::. .... :. ..: CCDS10 SLDENSDQQVDFQEYAVFLALITVMCNDFFQGCPDRP 70 80 90 >>CCDS1047.1 S100A1 gene_id:6271|Hs108|chr1 (94 aa) initn: 245 init1: 161 opt: 245 Z-score: 319.5 bits: 63.8 E(32554): 1.8e-11 Smith-Waterman score: 245; 46.0% identity (78.2% similar) in 87 aa overlap (1-85:1-87) 10 20 30 40 50 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELT-IGSKLQDAE-IARLME :. :. :. :. .:: .::.::::. :::::::::.: ::. . . .:.. . ..:. CCDS10 MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMK 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG .::.: : ::.:::::....::.. : CCDS10 ELDENGDGEVDFQEYVVLVAALTVACNNFFWENS 70 80 90 >>CCDS1043.1 S100A3 gene_id:6274|Hs108|chr1 (101 aa) initn: 227 init1: 157 opt: 236 Z-score: 308.0 bits: 61.7 E(32554): 7.8e-11 Smith-Waterman score: 236; 45.1% identity (70.3% similar) in 91 aa overlap (1-89:1-91) 10 20 30 40 50 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTI--GSKLQDAEIARLME :: ::.::.. .: :..:.:: :::. : . :::::.::::. ..... . ..: CCDS10 MARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMS 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG :: ::: ::.: ::: :. : : .: .: CCDS10 VLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ 70 80 90 100 90 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:34:34 2016 done: Sat Nov 5 00:34:34 2016 Total Scan time: 1.450 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]