FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8856, 90 aa 1>>>pF1KB8856 90 - 90 aa - 90 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9194+/-0.000309; mu= 5.6084+/- 0.019 mean_var=69.3896+/-13.833, 0's: 0 Z-trim(116.7): 93 B-trim: 84 in 1/53 Lambda= 0.153967 statistics sampled from 28067 (28166) to 28067 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.33), width: 16 Scan time: 3.510 The best scores are: opt bits E(85289) NP_055439 (OMIM: 114110) protein S100-A6 [Homo sap ( 90) 571 135.1 1.5e-32 XP_016857522 (OMIM: 114110) PREDICTED: protein S10 ( 90) 571 135.1 1.5e-32 NP_062427 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 318 78.9 1.4e-15 NP_002952 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 318 78.9 1.4e-15 XP_016857521 (OMIM: 176991) PREDICTED: protein S10 ( 92) 304 75.8 1.1e-14 NP_002953 (OMIM: 176991) protein S100-A5 [Homo sap ( 92) 304 75.8 1.1e-14 XP_016857520 (OMIM: 176991) PREDICTED: protein S10 ( 92) 304 75.8 1.1e-14 XP_011508162 (OMIM: 176991) PREDICTED: protein S10 ( 104) 304 75.8 1.2e-14 XP_016857519 (OMIM: 176991) PREDICTED: protein S10 ( 110) 304 75.8 1.3e-14 XP_016857518 (OMIM: 176991) PREDICTED: protein S10 ( 133) 304 75.8 1.5e-14 NP_005969 (OMIM: 176993) protein S100-A2 [Homo sap ( 97) 273 68.9 1.3e-12 NP_006262 (OMIM: 176940) protein S100-A1 [Homo sap ( 94) 245 62.7 9.8e-11 NP_002951 (OMIM: 176992) protein S100-A3 [Homo sap ( 101) 236 60.7 4.2e-10 NP_006263 (OMIM: 176990) protein S100-B [Homo sapi ( 92) 228 58.9 1.3e-09 XP_016883913 (OMIM: 176990) PREDICTED: protein S10 ( 92) 228 58.9 1.3e-09 XP_016864660 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 XP_011541543 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 NP_570128 (OMIM: 610103) protein S100-Z [Homo sapi ( 99) 221 57.4 4.1e-09 XP_011541542 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 XP_016864662 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 XP_016864661 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 XP_011541547 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 XP_011541546 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 XP_011541541 (OMIM: 610103) PREDICTED: protein S10 ( 99) 221 57.4 4.1e-09 NP_005971 (OMIM: 600614) protein S100-P [Homo sapi ( 95) 209 54.7 2.5e-08 NP_005612 (OMIM: 603112) protein S100-A12 [Homo sa ( 92) 186 49.6 8.4e-07 NP_005611 (OMIM: 603114) protein S100-A11 [Homo sa ( 105) 178 47.8 3.3e-06 NP_002956 (OMIM: 123886) protein S100-A9 [Homo sap ( 114) 176 47.4 4.8e-06 NP_002957 (OMIM: 114085) protein S100-A10 [Homo sa ( 97) 151 41.8 0.00019 NP_004048 (OMIM: 302020) protein S100-G [Homo sapi ( 79) 148 41.1 0.00026 XP_016885330 (OMIM: 302020) PREDICTED: protein S10 ( 79) 148 41.1 0.00026 NP_001019382 (OMIM: 601989) protein S100-A13 [Homo ( 98) 147 40.9 0.00036 XP_005245491 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 NP_005970 (OMIM: 601989) protein S100-A13 [Homo sa ( 98) 147 40.9 0.00036 XP_011508164 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 XP_016857523 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 XP_016857525 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 NP_001019383 (OMIM: 601989) protein S100-A13 [Homo ( 98) 147 40.9 0.00036 XP_016857524 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 NP_001019381 (OMIM: 601989) protein S100-A13 [Homo ( 98) 147 40.9 0.00036 XP_011508166 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 NP_001019384 (OMIM: 601989) protein S100-A13 [Homo ( 98) 147 40.9 0.00036 XP_011508165 (OMIM: 601989) PREDICTED: protein S10 ( 98) 147 40.9 0.00036 NP_001306130 (OMIM: 123885) protein S100-A8 isofor ( 93) 141 39.6 0.00087 NP_002955 (OMIM: 123885) protein S100-A8 isoform d ( 93) 141 39.6 0.00087 NP_001306127 (OMIM: 123885) protein S100-A8 isofor ( 101) 141 39.6 0.00094 NP_001306126 (OMIM: 123885) protein S100-A8 isofor ( 116) 141 39.6 0.0011 NP_001306125 (OMIM: 123885) protein S100-A8 isofor ( 117) 141 39.6 0.0011 XP_011507833 (OMIM: 616284) PREDICTED: filaggrin-2 (2239) 158 43.8 0.0012 NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391) 158 43.8 0.0012 >>NP_055439 (OMIM: 114110) protein S100-A6 [Homo sapiens (90 aa) initn: 571 init1: 571 opt: 571 Z-score: 705.4 bits: 135.1 E(85289): 1.5e-32 Smith-Waterman score: 571; 100.0% identity (100.0% similar) in 90 aa overlap (1-90:1-90) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL 10 20 30 40 50 60 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :::::::::::::::::::::::::::::: NP_055 DRNKDQEVNFQEYVTFLGALALIYNEALKG 70 80 90 >>XP_016857522 (OMIM: 114110) PREDICTED: protein S100-A6 (90 aa) initn: 571 init1: 571 opt: 571 Z-score: 705.4 bits: 135.1 E(85289): 1.5e-32 Smith-Waterman score: 571; 100.0% identity (100.0% similar) in 90 aa overlap (1-90:1-90) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL 10 20 30 40 50 60 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :::::::::::::::::::::::::::::: XP_016 DRNKDQEVNFQEYVTFLGALALIYNEALKG 70 80 90 >>NP_062427 (OMIM: 114210) protein S100-A4 [Homo sapiens (101 aa) initn: 299 init1: 188 opt: 318 Z-score: 400.9 bits: 78.9 E(85289): 1.4e-15 Smith-Waterman score: 318; 50.0% identity (81.5% similar) in 92 aa overlap (1-90:1-92) 10 20 30 40 50 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELT--IGSKLQDAEIARLME :::::..:. ..:. ::::::.:::: :.:.:::::. .:: .:.. ..: . .:: NP_062 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG .:: :.:.::.:::: .::. .:.. :: ..: NP_062 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK 70 80 90 100 >>NP_002952 (OMIM: 114210) protein S100-A4 [Homo sapiens (101 aa) initn: 299 init1: 188 opt: 318 Z-score: 400.9 bits: 78.9 E(85289): 1.4e-15 Smith-Waterman score: 318; 50.0% identity (81.5% similar) in 92 aa overlap (1-90:1-92) 10 20 30 40 50 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELT--IGSKLQDAEIARLME :::::..:. ..:. ::::::.:::: :.:.:::::. .:: .:.. ..: . .:: NP_002 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG .:: :.:.::.:::: .::. .:.. :: ..: NP_002 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK 70 80 90 100 >>XP_016857521 (OMIM: 176991) PREDICTED: protein S100-A5 (92 aa) initn: 299 init1: 184 opt: 304 Z-score: 384.7 bits: 75.8 E(85289): 1.1e-14 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:1-85) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL : ::..:. .:. :::::::::.: :::.:::::::.::: .: ..... : ::..: XP_016 METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLG-EMKESSIDDLMKSL 10 20 30 40 50 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :.:.:::..:.:: .:: : . ::. XP_016 DKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 60 70 80 90 >>NP_002953 (OMIM: 176991) protein S100-A5 [Homo sapiens (92 aa) initn: 299 init1: 184 opt: 304 Z-score: 384.7 bits: 75.8 E(85289): 1.1e-14 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:1-85) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL : ::..:. .:. :::::::::.: :::.:::::::.::: .: ..... : ::..: NP_002 METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLG-EMKESSIDDLMKSL 10 20 30 40 50 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :.:.:::..:.:: .:: : . ::. NP_002 DKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 60 70 80 90 >>XP_016857520 (OMIM: 176991) PREDICTED: protein S100-A5 (92 aa) initn: 299 init1: 184 opt: 304 Z-score: 384.7 bits: 75.8 E(85289): 1.1e-14 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:1-85) 10 20 30 40 50 60 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDL : ::..:. .:. :::::::::.: :::.:::::::.::: .: ..... : ::..: XP_016 METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLG-EMKESSIDDLMKSL 10 20 30 40 50 70 80 90 pF1KB8 DRNKDQEVNFQEYVTFLGALALIYNEALKG :.:.:::..:.:: .:: : . ::. XP_016 DKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 60 70 80 90 >>XP_011508162 (OMIM: 176991) PREDICTED: protein S100-A5 (104 aa) initn: 299 init1: 184 opt: 304 Z-score: 383.8 bits: 75.8 E(85289): 1.2e-14 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:13-97) 10 20 30 40 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKL : ::..:. .:. :::::::::.: :::.:::::::.::: .: .. XP_011 MGHSSISELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLG-EM 10 20 30 40 50 50 60 70 80 90 pF1KB8 QDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNEALKG ... : ::..::.:.:::..:.:: .:: : . ::. XP_011 KESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 60 70 80 90 100 >>XP_016857519 (OMIM: 176991) PREDICTED: protein S100-A5 (110 aa) initn: 299 init1: 184 opt: 304 Z-score: 383.4 bits: 75.8 E(85289): 1.3e-14 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:19-103) 10 20 30 40 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKEL : ::..:. .:. :::::::::.: :::.:::::::.::: XP_016 MPAAWILWAHSHSELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKEL 10 20 30 40 50 60 50 60 70 80 90 pF1KB8 TIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNEALKG .: ..... : ::..::.:.:::..:.:: .:: : . ::. XP_016 CLG-EMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 70 80 90 100 110 >>XP_016857518 (OMIM: 176991) PREDICTED: protein S100-A5 (133 aa) initn: 308 init1: 184 opt: 304 Z-score: 382.1 bits: 75.8 E(85289): 1.5e-14 Smith-Waterman score: 304; 53.5% identity (81.4% similar) in 86 aa overlap (1-86:42-126) 10 20 30 pF1KB8 MACPLDQAIGLLVAIFHKYSGREGDKHTLS : ::..:. .:. :::::::::.: ::: XP_016 REIKAEGSEREAMPAAWILWAHSHSELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLS 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 KKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNEALKG .:::::::.::: .: ..... : ::..::.:.:::..:.:: .:: : . ::. XP_016 RKELKELIKKELCLG-EMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLE 80 90 100 110 120 130 XP_016 DNK 90 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:34:34 2016 done: Sat Nov 5 00:34:35 2016 Total Scan time: 3.510 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]