FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8860, 97 aa 1>>>pF1KB8860 97 - 97 aa - 97 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9867+/-0.000331; mu= 10.8561+/- 0.021 mean_var=60.6969+/-11.960, 0's: 0 Z-trim(116.5): 87 B-trim: 1552 in 2/53 Lambda= 0.164623 statistics sampled from 27682 (27776) to 27682 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.326), width: 16 Scan time: 3.310 The best scores are: opt bits E(85289) NP_002957 (OMIM: 114085) protein S100-A10 [Homo sa ( 97) 661 164.6 2.2e-41 XP_011541547 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 XP_011541541 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 XP_011541546 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 XP_011541542 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 XP_016864660 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 XP_011541543 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 NP_570128 (OMIM: 610103) protein S100-Z [Homo sapi ( 99) 311 81.5 2.4e-16 XP_016864662 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 XP_016864661 (OMIM: 610103) PREDICTED: protein S10 ( 99) 311 81.5 2.4e-16 NP_006262 (OMIM: 176940) protein S100-A1 [Homo sap ( 94) 289 76.3 8.5e-15 NP_005971 (OMIM: 600614) protein S100-P [Homo sapi ( 95) 257 68.7 1.7e-12 NP_005611 (OMIM: 603114) protein S100-A11 [Homo sa ( 105) 254 68.0 2.9e-12 NP_062427 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 225 61.1 3.4e-10 NP_002952 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 225 61.1 3.4e-10 NP_005969 (OMIM: 176993) protein S100-A2 [Homo sap ( 97) 220 59.9 7.4e-10 NP_006263 (OMIM: 176990) protein S100-B [Homo sapi ( 92) 218 59.4 9.9e-10 XP_016883913 (OMIM: 176990) PREDICTED: protein S10 ( 92) 218 59.4 9.9e-10 XP_016857521 (OMIM: 176991) PREDICTED: protein S10 ( 92) 178 49.9 7.2e-07 NP_002953 (OMIM: 176991) protein S100-A5 [Homo sap ( 92) 178 49.9 7.2e-07 XP_016857520 (OMIM: 176991) PREDICTED: protein S10 ( 92) 178 49.9 7.2e-07 XP_011508162 (OMIM: 176991) PREDICTED: protein S10 ( 104) 178 49.9 7.9e-07 XP_016857519 (OMIM: 176991) PREDICTED: protein S10 ( 110) 178 50.0 8.3e-07 XP_016857518 (OMIM: 176991) PREDICTED: protein S10 ( 133) 178 50.0 9.7e-07 NP_001116437 (OMIM: 613259) repetin [Homo sapiens] ( 784) 185 52.1 1.3e-06 NP_005612 (OMIM: 603112) protein S100-A12 [Homo sa ( 92) 169 47.8 3.2e-06 NP_002956 (OMIM: 123886) protein S100-A9 [Homo sap ( 114) 161 45.9 1.4e-05 XP_011507833 (OMIM: 616284) PREDICTED: filaggrin-2 (2239) 174 49.8 1.9e-05 NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391) 174 49.8 2e-05 XP_016857522 (OMIM: 114110) PREDICTED: protein S10 ( 90) 151 43.5 6e-05 NP_055439 (OMIM: 114110) protein S100-A6 [Homo sap ( 90) 151 43.5 6e-05 XP_016885330 (OMIM: 302020) PREDICTED: protein S10 ( 79) 148 42.8 8.8e-05 NP_004048 (OMIM: 302020) protein S100-G [Homo sapi ( 79) 148 42.8 8.8e-05 NP_057274 (OMIM: 611312) cornulin [Homo sapiens] ( 495) 153 44.4 0.00017 NP_001306130 (OMIM: 123885) protein S100-A8 isofor ( 93) 143 41.6 0.00023 NP_002955 (OMIM: 123885) protein S100-A8 isoform d ( 93) 143 41.6 0.00023 NP_001306127 (OMIM: 123885) protein S100-A8 isofor ( 101) 143 41.6 0.00025 NP_002951 (OMIM: 176992) protein S100-A3 [Homo sap ( 101) 143 41.6 0.00025 NP_001306126 (OMIM: 123885) protein S100-A8 isofor ( 116) 143 41.7 0.00028 NP_001306125 (OMIM: 123885) protein S100-A8 isofor ( 117) 143 41.7 0.00028 XP_005245419 (OMIM: 607986) PREDICTED: protein S10 ( 104) 136 40.0 0.0008 NP_065723 (OMIM: 607986) protein S100-A14 [Homo sa ( 104) 136 40.0 0.0008 XP_016857364 (OMIM: 607986) PREDICTED: protein S10 ( 104) 136 40.0 0.0008 NP_009044 (OMIM: 190370) trichohyalin [Homo sapien (1943) 148 43.6 0.0012 NP_001009931 (OMIM: 616293) hornerin [Homo sapiens (2850) 149 43.9 0.0014 NP_001019383 (OMIM: 601989) protein S100-A13 [Homo ( 98) 127 37.8 0.0033 XP_005245491 (OMIM: 601989) PREDICTED: protein S10 ( 98) 127 37.8 0.0033 NP_001019381 (OMIM: 601989) protein S100-A13 [Homo ( 98) 127 37.8 0.0033 XP_011508166 (OMIM: 601989) PREDICTED: protein S10 ( 98) 127 37.8 0.0033 XP_016857524 (OMIM: 601989) PREDICTED: protein S10 ( 98) 127 37.8 0.0033 >>NP_002957 (OMIM: 114085) protein S100-A10 [Homo sapien (97 aa) initn: 661 init1: 661 opt: 661 Z-score: 864.0 bits: 164.6 E(85289): 2.2e-41 Smith-Waterman score: 661; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97) 10 20 30 40 50 60 pF1KB8 MPSQMEHAMETMMFTFHKFAGDKGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPSQMEHAMETMMFTFHKFAGDKGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLD 10 20 30 40 50 60 70 80 90 pF1KB8 QCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::::::::::::::::::::::::::::::::::::: NP_002 QCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK 70 80 90 >>XP_011541547 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541541 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541546 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541542 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_016864660 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_016 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_011541543 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_011 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>NP_570128 (OMIM: 610103) protein S100-Z [Homo sapiens] (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. NP_570 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: NP_570 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_016864662 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_016 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>XP_016864661 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 317 init1: 239 opt: 311 Z-score: 414.6 bits: 81.5 E(85289): 2.4e-16 Smith-Waterman score: 311; 46.5% identity (76.8% similar) in 99 aa overlap (1-96:1-99) 10 20 30 40 50 pF1KB8 MPSQMEHAMETMMFTFHKFAGD--KGY-LTKEDLRVLMEKEFPGFLENQKDPLAVDKIMK ::.:.: ::.::. ::...: : . :.: .:..:...:. :: ::. ::::.. XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 DLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK ::: .:..: :. : ..:.::.::::::: ..:.::: XP_016 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 97 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:10:46 2016 done: Fri Nov 4 16:10:46 2016 Total Scan time: 3.310 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]