FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8862, 101 aa 1>>>pF1KB8862 101 - 101 aa - 101 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6141+/-0.000308; mu= 13.4732+/- 0.019 mean_var=62.6707+/-12.514, 0's: 0 Z-trim(117.0): 47 B-trim: 804 in 1/57 Lambda= 0.162010 statistics sampled from 28522 (28573) to 28522 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.335), width: 16 Scan time: 3.730 The best scores are: opt bits E(85289) NP_002954 (OMIM: 600353) protein S100-A7 [Homo sap ( 101) 672 164.7 2.3e-41 NP_005611 (OMIM: 603114) protein S100-A11 [Homo sa ( 105) 163 45.7 1.6e-05 NP_002956 (OMIM: 123886) protein S100-A9 [Homo sap ( 114) 151 42.9 0.00012 NP_005612 (OMIM: 603112) protein S100-A12 [Homo sa ( 92) 150 42.6 0.00012 XP_011541546 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 XP_016864660 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 XP_016864661 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 XP_011541542 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 NP_570128 (OMIM: 610103) protein S100-Z [Homo sapi ( 99) 140 40.3 0.00062 XP_011541547 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 XP_016864662 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 XP_011541543 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 XP_011541541 (OMIM: 610103) PREDICTED: protein S10 ( 99) 140 40.3 0.00062 NP_001306130 (OMIM: 123885) protein S100-A8 isofor ( 93) 136 39.4 0.0011 NP_002955 (OMIM: 123885) protein S100-A8 isoform d ( 93) 136 39.4 0.0011 NP_001306127 (OMIM: 123885) protein S100-A8 isofor ( 101) 136 39.4 0.0012 NP_001306126 (OMIM: 123885) protein S100-A8 isofor ( 116) 136 39.4 0.0013 NP_001306125 (OMIM: 123885) protein S100-A8 isofor ( 117) 136 39.4 0.0013 XP_016857522 (OMIM: 114110) PREDICTED: protein S10 ( 90) 134 38.9 0.0015 NP_055439 (OMIM: 114110) protein S100-A6 [Homo sap ( 90) 134 38.9 0.0015 NP_006263 (OMIM: 176990) protein S100-B [Homo sapi ( 92) 134 38.9 0.0016 XP_016883913 (OMIM: 176990) PREDICTED: protein S10 ( 92) 134 38.9 0.0016 XP_016885330 (OMIM: 302020) PREDICTED: protein S10 ( 79) 132 38.4 0.0019 NP_004048 (OMIM: 302020) protein S100-G [Homo sapi ( 79) 132 38.4 0.0019 NP_005971 (OMIM: 600614) protein S100-P [Homo sapi ( 95) 132 38.4 0.0022 NP_002007 (OMIM: 135940,146700,605803) filaggrin [ (4061) 144 42.6 0.0052 NP_002957 (OMIM: 114085) protein S100-A10 [Homo sa ( 97) 124 36.6 0.0082 >>NP_002954 (OMIM: 600353) protein S100-A7 [Homo sapiens (101 aa) initn: 672 init1: 672 opt: 672 Z-score: 863.5 bits: 164.7 E(85289): 2.3e-41 Smith-Waterman score: 672; 99.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101) 10 20 30 40 50 60 pF1KB8 MSNTQAERSIIGMIDMFHKYTRRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLADVFE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_002 MSNTQAERSIIGMIDMFHKYTRRDDKIEKPSLLTMMKENFPNFLSACDKKGTNYLADVFE 10 20 30 40 50 60 70 80 90 100 pF1KB8 KKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ ::::::::::::::::::::::::::::::::::::::::: NP_002 KKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ 70 80 90 100 >>NP_005611 (OMIM: 603114) protein S100-A11 [Homo sapien (105 aa) initn: 123 init1: 62 opt: 163 Z-score: 220.3 bits: 45.7 E(85289): 1.6e-05 Smith-Waterman score: 163; 33.0% identity (63.9% similar) in 97 aa overlap (2-95:6-100) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYTRRDD---KIDKPSLLTMMKENFPNFLSACDKKGTN : :..:: : ..: .:.::. .: ..: .:..:. .. : . ..: . NP_005 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTK--NQKDPG 10 20 30 40 50 60 70 80 90 100 pF1KB8 YLADVFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ : ...: : : : ..::::::.:.: .: : . :.: NP_005 VLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT 60 70 80 90 100 >>NP_002956 (OMIM: 123886) protein S100-A9 [Homo sapiens (114 aa) initn: 105 init1: 51 opt: 151 Z-score: 204.6 bits: 42.9 E(85289): 0.00012 Smith-Waterman score: 151; 26.4% identity (64.8% similar) in 91 aa overlap (4-91:6-95) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYTRR---DDKIDKPSLLTMMKENFPNFLSACDKKGTNYL .: ::.: .:. ::.:. . : ... . ...... :::. ..:. . . NP_002 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKK-ENKNEKVI 10 20 30 40 50 60 70 80 90 100 pF1KB8 ADVFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ ..: : : ::...: ::. :.. .. :.. : NP_002 EHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP 60 70 80 90 100 110 >>NP_005612 (OMIM: 603112) protein S100-A12 [Homo sapien (92 aa) initn: 77 init1: 43 opt: 150 Z-score: 204.6 bits: 42.6 E(85289): 0.00012 Smith-Waterman score: 150; 26.4% identity (62.6% similar) in 91 aa overlap (4-91:2-90) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYTRRD---DKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :. :. . :....::.:. : : ..: : .. ... : .. . : . . NP_005 MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIK--NIKDKAVIDE 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ .:. : :.:...::.::.::.. : ..: NP_005 IFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE 60 70 80 90 >>XP_011541546 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 104 init1: 60 opt: 140 Z-score: 191.6 bits: 40.3 E(85289): 0.00062 Smith-Waterman score: 140; 31.6% identity (68.4% similar) in 79 aa overlap (4-79:3-79) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYT---RRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :: : .. :: .::.:. :. :..: : ...... .::: :.:. :. . XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLS-CQKE-TQLVDK 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ . . : :.:...::.::. .. XP_011 IVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_016864660 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 104 init1: 60 opt: 140 Z-score: 191.6 bits: 40.3 E(85289): 0.00062 Smith-Waterman score: 140; 31.6% identity (68.4% similar) in 79 aa overlap (4-79:3-79) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYT---RRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :: : .. :: .::.:. :. :..: : ...... .::: :.:. :. . XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLS-CQKE-TQLVDK 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ . . : :.:...::.::. .. XP_016 IVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_016864661 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 104 init1: 60 opt: 140 Z-score: 191.6 bits: 40.3 E(85289): 0.00062 Smith-Waterman score: 140; 31.6% identity (68.4% similar) in 79 aa overlap (4-79:3-79) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYT---RRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :: : .. :: .::.:. :. :..: : ...... .::: :.:. :. . XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLS-CQKE-TQLVDK 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ . . : :.:...::.::. .. XP_016 IVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_011541542 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 104 init1: 60 opt: 140 Z-score: 191.6 bits: 40.3 E(85289): 0.00062 Smith-Waterman score: 140; 31.6% identity (68.4% similar) in 79 aa overlap (4-79:3-79) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYT---RRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :: : .. :: .::.:. :. :..: : ...... .::: :.:. :. . XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLS-CQKE-TQLVDK 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ . . : :.:...::.::. .. XP_011 IVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>NP_570128 (OMIM: 610103) protein S100-Z [Homo sapiens] (99 aa) initn: 104 init1: 60 opt: 140 Z-score: 191.6 bits: 40.3 E(85289): 0.00062 Smith-Waterman score: 140; 31.6% identity (68.4% similar) in 79 aa overlap (4-79:3-79) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYT---RRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :: : .. :: .::.:. :. :..: : ...... .::: :.:. :. . NP_570 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLS-CQKE-TQLVDK 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ . . : :.:...::.::. .. NP_570 IVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_011541547 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 104 init1: 60 opt: 140 Z-score: 191.6 bits: 40.3 E(85289): 0.00062 Smith-Waterman score: 140; 31.6% identity (68.4% similar) in 79 aa overlap (4-79:3-79) 10 20 30 40 50 pF1KB8 MSNTQAERSIIGMIDMFHKYT---RRDDKIDKPSLLTMMKENFPNFLSACDKKGTNYLAD :: : .. :: .::.:. :. :..: : ...... .::: :.:. :. . XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLS-CQKE-TQLVDK 10 20 30 40 50 60 70 80 90 100 pF1KB8 VFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ . . : :.:...::.::. .. XP_011 IVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 101 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:12:18 2016 done: Fri Nov 4 16:12:19 2016 Total Scan time: 3.730 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]