FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8863, 101 aa 1>>>pF1KB8863 101 - 101 aa - 101 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2211+/-0.000635; mu= 9.3411+/- 0.038 mean_var=60.9427+/-11.986, 0's: 0 Z-trim(110.4): 33 B-trim: 34 in 1/50 Lambda= 0.164291 statistics sampled from 11534 (11567) to 11534 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.355), width: 16 Scan time: 1.220 The best scores are: opt bits E(32554) CCDS1042.1 S100A4 gene_id:6275|Hs108|chr1 ( 101) 684 169.8 2.5e-43 CCDS1044.1 S100A2 gene_id:6273|Hs108|chr1 ( 97) 415 106.1 3.7e-24 CCDS1040.1 S100A6 gene_id:6277|Hs108|chr1 ( 90) 318 83.1 2.9e-17 CCDS1047.1 S100A1 gene_id:6271|Hs108|chr1 ( 94) 310 81.2 1.1e-16 CCDS1043.1 S100A3 gene_id:6274|Hs108|chr1 ( 101) 309 81.0 1.4e-16 CCDS1041.2 S100A5 gene_id:6276|Hs108|chr1 ( 92) 299 78.6 6.8e-16 CCDS43333.1 S100Z gene_id:170591|Hs108|chr5 ( 99) 291 76.7 2.7e-15 CCDS13736.1 S100B gene_id:6285|Hs108|chr21 ( 92) 289 76.2 3.5e-15 CCDS3391.1 S100P gene_id:6286|Hs108|chr4 ( 95) 258 68.9 5.8e-13 >>CCDS1042.1 S100A4 gene_id:6275|Hs108|chr1 (101 aa) initn: 684 init1: 684 opt: 684 Z-score: 891.4 bits: 169.8 E(32554): 2.5e-43 Smith-Waterman score: 684; 100.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS 10 20 30 40 50 60 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK ::::::::::::::::::::::::::::::::::::::::: CCDS10 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK 70 80 90 100 >>CCDS1044.1 S100A2 gene_id:6273|Hs108|chr1 (97 aa) initn: 420 init1: 411 opt: 415 Z-score: 547.1 bits: 106.1 E(32554): 3.7e-24 Smith-Waterman score: 415; 61.5% identity (87.5% similar) in 96 aa overlap (1-96:1-96) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS : ::.:: :.:.:::::: .:::::::.:.:.:::: .:::::.:...:: ...:::. CCDS10 MCSSLEQALAVLVTTFHKYSCQEGDKFKLSKGEMKELLHKELPSFVGEKVDEEGLKKLMG 10 20 30 40 50 60 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .:: : :..:::::: :::. :..:::.::.: ::. CCDS10 SLDENSDQQVDFQEYAVFLALITVMCNDFFQGCPDRP 70 80 90 >>CCDS1040.1 S100A6 gene_id:6277|Hs108|chr1 (90 aa) initn: 299 init1: 188 opt: 318 Z-score: 423.4 bits: 83.1 E(32554): 2.9e-17 Smith-Waterman score: 318; 50.0% identity (81.5% similar) in 92 aa overlap (1-92:1-90) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS :::::..:. ..:. ::::::.:::: :.:.:::::. .:: .:.. ..: . .:: CCDS10 MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELT--IGSKLQDAEIARLME 10 20 30 40 50 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .:: :.:.::.:::: .::. .:.. :: ..: CCDS10 DLDRNKDQEVNFQEYVTFLGALALIYNEALKG 60 70 80 90 >>CCDS1047.1 S100A1 gene_id:6271|Hs108|chr1 (94 aa) initn: 310 init1: 310 opt: 310 Z-score: 412.8 bits: 81.2 E(32554): 1.1e-16 Smith-Waterman score: 310; 51.1% identity (80.0% similar) in 90 aa overlap (1-90:1-90) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS :. :: :.......:: .:::::::.::.:.:::::: :: .:: . : : .:.:. CCDS10 MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMK 10 20 30 40 50 60 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .:: : :.::::::: :... ... ::.:: CCDS10 ELDENGDGEVDFQEYVVLVAALTVACNNFFWENS 70 80 90 >>CCDS1043.1 S100A3 gene_id:6274|Hs108|chr1 (101 aa) initn: 243 init1: 243 opt: 309 Z-score: 411.1 bits: 81.0 E(32554): 1.4e-16 Smith-Waterman score: 309; 45.9% identity (75.5% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS :: :::.:. ..: ::..:.:. :::.:: ..:::::: .:: .. . : ..:.:: CCDS10 MARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMS 10 20 30 40 50 60 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK ::.:.: :::: :: :.:. ..:.:.:. :.. : CCDS10 VLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ 70 80 90 100 >>CCDS1041.2 S100A5 gene_id:6276|Hs108|chr1 (92 aa) initn: 301 init1: 180 opt: 299 Z-score: 398.9 bits: 78.6 E(32554): 6.8e-16 Smith-Waterman score: 299; 53.3% identity (80.0% similar) in 90 aa overlap (1-90:1-87) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS : :::::: .::.:::::::.::.:. :...:::::. .:: ::. :.... ::. CCDS10 METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKEL--CLGE-MKESSIDDLMK 10 20 30 40 50 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .::.: :.:.::.:: :::. . : :.:: CCDS10 SLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK 60 70 80 90 >>CCDS43333.1 S100Z gene_id:170591|Hs108|chr5 (99 aa) initn: 304 init1: 287 opt: 291 Z-score: 388.1 bits: 76.7 E(32554): 2.7e-15 Smith-Waterman score: 291; 46.7% identity (76.7% similar) in 90 aa overlap (1-90:1-90) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS : :: :.:.:. ::.::::: .:::.:.::: :: ::: ::. . . .:... CCDS43 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 10 20 30 40 50 60 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .::.:.::::::.:. :... ... ::..: CCDS43 DLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 70 80 90 >>CCDS13736.1 S100B gene_id:6285|Hs108|chr21 (92 aa) initn: 289 init1: 289 opt: 289 Z-score: 386.1 bits: 76.2 E(32554): 3.5e-15 Smith-Waterman score: 289; 48.3% identity (80.5% similar) in 87 aa overlap (5-91:4-90) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS ::::. .....::.:::.:::: ::.:::::::.. :: :: . .. . .:.: CCDS13 MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVME 10 20 30 40 50 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .::.. :.: ::::. .:.. .. :.:::: CCDS13 TLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE 60 70 80 90 >>CCDS3391.1 S100P gene_id:6286|Hs108|chr4 (95 aa) initn: 258 init1: 258 opt: 258 Z-score: 346.1 bits: 68.9 E(32554): 5.8e-13 Smith-Waterman score: 258; 43.7% identity (78.2% similar) in 87 aa overlap (5-91:4-90) 10 20 30 40 50 60 pF1KB8 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS :: :. .....: .:::.::. :.:.::: :. .:::.:: . :. : .::.. CCDS33 MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLK 10 20 30 40 50 70 80 90 100 pF1KB8 NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK .::.: : .:::.:. ::.. :. :...:: CCDS33 DLDANGDAQVDFSEFIVFVAAITSACHKYFEKAGLK 60 70 80 90 101 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:12:53 2016 done: Fri Nov 4 16:12:54 2016 Total Scan time: 1.220 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]