FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8869, 133 aa 1>>>pF1KB8869 133 - 133 aa - 133 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6940+/-0.000332; mu= 8.9350+/- 0.021 mean_var=65.1813+/-13.002, 0's: 0 Z-trim(115.1): 8 B-trim: 0 in 0/55 Lambda= 0.158859 statistics sampled from 25303 (25310) to 25303 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.297), width: 16 Scan time: 4.950 The best scores are: opt bits E(85289) NP_057056 (OMIM: 613715,613717) DNA-directed RNA p ( 133) 874 208.6 2.5e-54 XP_005266469 (OMIM: 613715,613717) PREDICTED: DNA- ( 133) 874 208.6 2.5e-54 NP_006225 (OMIM: 604150) DNA-directed RNA polymera ( 117) 214 57.3 7.5e-09 XP_016867842 (OMIM: 604150) PREDICTED: DNA-directe ( 116) 206 55.5 2.7e-08 XP_005250509 (OMIM: 604150) PREDICTED: DNA-directe ( 159) 192 52.3 3.3e-07 NP_116581 (OMIM: 609881) DNA-directed RNA polymera ( 115) 189 51.6 3.9e-07 >>NP_057056 (OMIM: 613715,613717) DNA-directed RNA polym (133 aa) initn: 874 init1: 874 opt: 874 Z-score: 1096.5 bits: 208.6 E(85289): 2.5e-54 Smith-Waterman score: 874; 100.0% identity (100.0% similar) in 133 aa overlap (1-133:1-133) 10 20 30 40 50 60 pF1KB8 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD 70 80 90 100 110 120 130 pF1KB8 YKDQKASRNESTF ::::::::::::: NP_057 YKDQKASRNESTF 130 >>XP_005266469 (OMIM: 613715,613717) PREDICTED: DNA-dire (133 aa) initn: 874 init1: 874 opt: 874 Z-score: 1096.5 bits: 208.6 E(85289): 2.5e-54 Smith-Waterman score: 874; 100.0% identity (100.0% similar) in 133 aa overlap (1-133:1-133) 10 20 30 40 50 60 pF1KB8 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD 70 80 90 100 110 120 130 pF1KB8 YKDQKASRNESTF ::::::::::::: XP_005 YKDQKASRNESTF 130 >>NP_006225 (OMIM: 604150) DNA-directed RNA polymerase I (117 aa) initn: 224 init1: 190 opt: 214 Z-score: 279.9 bits: 57.3 E(85289): 7.5e-09 Smith-Waterman score: 214; 32.7% identity (68.3% similar) in 104 aa overlap (20-123:14-114) 10 20 30 40 50 60 pF1KB8 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM :::.: ... . . . :. :....::::::: .. ... NP_006 MNAPPAFESFLLFEGEKKITIN--KDTKVPNACL-FTINKEDHTLGNIIKSQLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD :.:.: : :: . :: : :: .:.:: : : ....:.. . . ..:...::: NP_006 KDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKD 60 70 80 90 100 110 130 pF1KB8 YKDQKASRNESTF .. NP_006 KQEGIE >>XP_016867842 (OMIM: 604150) PREDICTED: DNA-directed RN (116 aa) initn: 221 init1: 190 opt: 206 Z-score: 270.0 bits: 55.5 E(85289): 2.7e-08 Smith-Waterman score: 206; 32.7% identity (66.3% similar) in 104 aa overlap (20-123:14-113) 10 20 30 40 50 60 pF1KB8 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM :::. : . . . . :. :....::::::: .. ... XP_016 MNAPPAFESFLLFEGEKIT---INKDTKVPNACL-FTINKEDHTLGNIIKSQLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD :.:.: : :: . :: : :: .:.:: : : ....:.. . . ..:...::: XP_016 KDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKD 60 70 80 90 100 110 130 pF1KB8 YKDQKASRNESTF .. XP_016 KQEGIE >>XP_005250509 (OMIM: 604150) PREDICTED: DNA-directed RN (159 aa) initn: 198 init1: 164 opt: 192 Z-score: 250.5 bits: 52.3 E(85289): 3.3e-07 Smith-Waterman score: 192; 32.6% identity (66.3% similar) in 95 aa overlap (20-114:14-105) 10 20 30 40 50 60 pF1KB8 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM :::.: ... . . . :. :....::::::: .. ... XP_005 MNAPPAFESFLLFEGEKKITIN--KDTKVPNACL-FTINKEDHTLGNIIKSQLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD :.:.: : :: . :: : :: .:.:: : : ....:.. . . ..: XP_005 KDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVRAGP 60 70 80 90 100 110 130 pF1KB8 YKDQKASRNESTF XP_005 GGADGVGWTLARVPRPGTALACFFGGPGGEAAVMEEQGLPPQAPGHVD 120 130 140 150 >>NP_116581 (OMIM: 609881) DNA-directed RNA polymerase I (115 aa) initn: 182 init1: 164 opt: 189 Z-score: 249.0 bits: 51.6 E(85289): 3.9e-07 Smith-Waterman score: 189; 31.3% identity (65.7% similar) in 99 aa overlap (20-118:14-108) 10 20 30 40 50 60 pF1KB8 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM :::. : . . . . . :. :....::::::: .. ... NP_116 MNAPPAFESFLLFEGEKIT---INKDTKVPKACL-FTINKEDHTLGNIIKSQLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD :.:.: : :: . :: : :: .:.:: : : ....:.. . . ..:.. . NP_116 KDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLP 60 70 80 90 100 110 130 pF1KB8 YKDQKASRNESTF NP_116 LRLLP 133 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:15:49 2016 done: Fri Nov 4 16:15:49 2016 Total Scan time: 4.950 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]