FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8870, 134 aa
  1>>>pF1KB8870 134 - 134 aa - 134 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5677+/-0.000316; mu= 9.8126+/- 0.020
 mean_var=65.1504+/-12.988, 0's: 0 Z-trim(116.2): 39  B-trim: 0 in 0/53
 Lambda= 0.158897
 statistics sampled from 27234 (27273) to 27234 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.32), width:  16
 Scan time:  4.240

The best scores are:                                      opt bits E(85289)
NP_002157 (OMIM: 600386) DNA-binding protein inhib ( 134)  868 207.1   7e-54
NP_001537 (OMIM: 600581) DNA-binding protein inhib ( 161)  305 78.1 5.8e-15
NP_002156 (OMIM: 600349) DNA-binding protein inhib ( 155)  301 77.1 1.1e-14
NP_851998 (OMIM: 600349) DNA-binding protein inhib ( 149)  286 73.7 1.1e-13
NP_002158 (OMIM: 600277) DNA-binding protein inhib ( 119)  275 71.1 5.3e-13


>>NP_002157 (OMIM: 600386) DNA-binding protein inhibitor  (134 aa)
 initn: 868 init1: 868 opt: 868  Z-score: 1088.3  bits: 207.1 E(85289): 7e-54
Smith-Waterman score: 868; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134)

               10        20        30        40        50        60
pF1KB8 MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF
               70        80        90       100       110       120

              130    
pF1KB8 PSELMSNDSKALCG
       ::::::::::::::
NP_002 PSELMSNDSKALCG
              130    

>>NP_001537 (OMIM: 600581) DNA-binding protein inhibitor  (161 aa)
 initn: 347 init1: 259 opt: 305  Z-score: 389.6  bits: 78.1 E(85289): 5.8e-15
Smith-Waterman score: 305; 54.3% identity (76.6% similar) in 94 aa overlap (25-109:53-146)

                     10        20        30         40        50   
pF1KB8       MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDP-MSLLYNMNDCYSKLKELVPSI
                                     ... .:.: . :  .::::::.:..:::.:
NP_001 LALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEPALCLQCDMNDCYSRLRRLVPTI
             30        40        50        60        70        80  

            60        70        80              90         100     
pF1KB8 PQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLH------HQRPGQNQAS--RTPLTT
       : ::::::.::::::::::::::.::..::...         :.  :   :.  :::::.
NP_001 PPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPPPAPPHHPAGTCPAAPPRTPLTA
             90       100       110       120       130       140  

         110       120       130    
pF1KB8 LNTDISILSLQASEFPSELMSNDSKALCG
       ::::                         
NP_001 LNTDPAGAVNKQGDSILCR          
            150       160           

>>NP_002156 (OMIM: 600349) DNA-binding protein inhibitor  (155 aa)
 initn: 336 init1: 249 opt: 301  Z-score: 384.9  bits: 77.1 E(85289): 1.1e-14
Smith-Waterman score: 314; 46.2% identity (70.0% similar) in 130 aa overlap (15-133:35-154)

                               10        20                30      
pF1KB8                 MKAFSPVRSVRKNSLSDHSLGISR------SKTP--VDDPMS--
                                     ::..:..:::      .. :  .:. .   
NP_002 SGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQQVNV
           10        20        30        40        50        60    

           40        50        60        70        80        90    
pF1KB8 LLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPG
       :::.:: :::.::::::..:::.::::.:::::::::: :::. :.:.  . .     ::
NP_002 LLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGT-----PG
           70        80        90       100       110              

           100       110       120       130    
pF1KB8 -QNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALCG
        ..   :.::.::: .:: :. .:.  :.     :.. :: 
NP_002 GRGLPVRAPLSTLNGEISALTAEAACVPA-----DDRILCR
     120       130       140            150     

>>NP_851998 (OMIM: 600349) DNA-binding protein inhibitor  (149 aa)
 initn: 307 init1: 249 opt: 286  Z-score: 366.5  bits: 73.7 E(85289): 1.1e-13
Smith-Waterman score: 293; 49.5% identity (73.0% similar) in 111 aa overlap (15-114:35-140)

                               10        20                30      
pF1KB8                 MKAFSPVRSVRKNSLSDHSLGISR------SKTP--VDDPMS--
                                     ::..:..:::      .. :  .:. .   
NP_851 SGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQQVNV
           10        20        30        40        50        60    

           40        50        60        70        80        90    
pF1KB8 LLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPG
       :::.:: :::.::::::..:::.::::.:::::::::: :::. :.:.  . .     ::
NP_851 LLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGT-----PG
           70        80        90       100       110              

           100       110       120       130    
pF1KB8 -QNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALCG
        ..   :.::.::: .:: :.                    
NP_851 GRGLPVRAPLSTLNGEISALTAEVRSRSDH           
     120       130       140                    

>>NP_002158 (OMIM: 600277) DNA-binding protein inhibitor  (119 aa)
 initn: 283 init1: 203 opt: 275  Z-score: 354.5  bits: 71.1 E(85289): 5.3e-13
Smith-Waterman score: 288; 41.0% identity (70.5% similar) in 139 aa overlap (1-133:1-118)

               10          20           30        40        50     
pF1KB8 MKAFSPVRSVRKN--SLSDHSLGISRS--KTPV-DDPMSLLYNMNDCYSKLKELVPSIPQ
       :::.::::.  .    ::..::.:.:.  : :. ..:.::: .:: :::.:.::::..:.
NP_002 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB8 NKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSL
       . ..:..::::.:::::::::..: ..:.        ::  .. . :.            
NP_002 GTQLSQVEILQRVIDYILDLQVVL-AEPA--------PGPPDGPHLPI------------
               70        80                 90                     

         120        130    
pF1KB8 QASEFPSEL-MSNDSKALCG
       :..:.  :: .:::....: 
NP_002 QTAELTPELVISNDKRSFCH
     100       110         




134 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:36:28 2016 done: Sat Nov  5 00:36:29 2016
 Total Scan time:  4.240 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]