FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8871, 158 aa 1>>>pF1KB8871 158 - 158 aa - 158 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3651+/-0.000314; mu= 11.5334+/- 0.019 mean_var=59.6264+/-12.256, 0's: 0 Z-trim(116.1): 18 B-trim: 0 in 0/50 Lambda= 0.166094 statistics sampled from 27008 (27026) to 27008 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.317), width: 16 Scan time: 4.980 The best scores are: opt bits E(85289) NP_006754 (OMIM: 601597) protein BTG2 [Homo sapien ( 158) 1062 262.3 2.3e-70 NP_001722 (OMIM: 109580) protein BTG1 [Homo sapien ( 171) 620 156.4 1.9e-38 NP_001230806 (OMIM: 605523) protein Tob1 isoform 1 ( 345) 352 92.3 7.6e-19 NP_005740 (OMIM: 605523) protein Tob1 isoform 1 [H ( 345) 352 92.3 7.6e-19 NP_057356 (OMIM: 607396) protein Tob2 [Homo sapien ( 344) 336 88.5 1.1e-17 XP_016884028 (OMIM: 607396) PREDICTED: protein Tob ( 344) 336 88.5 1.1e-17 XP_005261372 (OMIM: 607396) PREDICTED: protein Tob ( 344) 336 88.5 1.1e-17 XP_006724168 (OMIM: 607396) PREDICTED: protein Tob ( 344) 336 88.5 1.1e-17 NP_006797 (OMIM: 605674) protein BTG3 isoform b [H ( 252) 291 77.6 1.5e-14 XP_016883755 (OMIM: 605674) PREDICTED: protein BTG ( 252) 291 77.6 1.5e-14 XP_016883754 (OMIM: 605674) PREDICTED: protein BTG ( 252) 291 77.6 1.5e-14 NP_060059 (OMIM: 605673) protein BTG4 [Homo sapien ( 223) 280 75.0 8.1e-14 XP_011541182 (OMIM: 605673) PREDICTED: protein BTG ( 226) 280 75.0 8.2e-14 XP_011541181 (OMIM: 605673) PREDICTED: protein BTG ( 244) 280 75.0 8.8e-14 NP_001124386 (OMIM: 605674) protein BTG3 isoform a ( 296) 281 75.3 8.8e-14 XP_011527743 (OMIM: 605674) PREDICTED: protein BTG ( 306) 281 75.3 9.1e-14 XP_011541180 (OMIM: 605673) PREDICTED: protein BTG ( 255) 280 75.0 9.1e-14 XP_011541178 (OMIM: 605673) PREDICTED: protein BTG ( 273) 280 75.0 9.7e-14 >>NP_006754 (OMIM: 601597) protein BTG2 [Homo sapiens] (158 aa) initn: 1062 init1: 1062 opt: 1062 Z-score: 1384.2 bits: 262.3 E(85289): 2.3e-70 Smith-Waterman score: 1062; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC 70 80 90 100 110 120 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS :::::::::::::::::::::::::::::::::::::: NP_006 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS 130 140 150 >>NP_001722 (OMIM: 109580) protein BTG1 [Homo sapiens] (171 aa) initn: 693 init1: 611 opt: 620 Z-score: 811.2 bits: 156.4 E(85289): 1.9e-38 Smith-Waterman score: 686; 63.4% identity (86.0% similar) in 164 aa overlap (5-157:7-170) 10 20 30 40 50 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEK ... :. ::::::.:.:..:::.: .::..:..:: .::: :.::::::::::: NP_001 MHPFYTRAATMIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 PSKGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGS : ::::::::::::::::.:...:..::::. .: .:::::::::::::::::::::::: NP_001 PCKGSGYRCIRINHKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGS 70 80 90 100 110 120 120 130 140 150 pF1KB8 ICVLYEEAPLAASC----------GLLTCKNQVLLGRSSPSKNY-VMAVSS :::::: .: ..: . ..::...::::.:::::: .:.:: NP_001 ICVLYEASPAGGSTQNSTNVQMVDSRISCKEELLLGRTSPSKNYNMMTVSG 130 140 150 160 170 >>NP_001230806 (OMIM: 605523) protein Tob1 isoform 1 [Ho (345 aa) initn: 331 init1: 331 opt: 352 Z-score: 459.3 bits: 92.3 E(85289): 7.6e-19 Smith-Waterman score: 352; 40.5% identity (75.4% similar) in 126 aa overlap (9-134:1-124) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : :: .:..:. : : .. . ..:...:. :.. : ..:. ::.:::: NP_001 MQLEIQVALNFIISYLYNK--LPRRRVNIFGEELERLLKKKYEGHWYPEKPY 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC ::::.:::.:..:.::.: ..... ::. ... ::..:..:.::.::::.::: : . NP_001 KGSGFRCIHIGEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVK 60 70 80 90 100 110 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS ::: . .: : NP_001 VLYVDDNNENGCELDKEIKNSFNPEAQVFMPISDPASSVSSSPSPPFGHSAAVSPTFMPR 120 130 140 150 160 170 >>NP_005740 (OMIM: 605523) protein Tob1 isoform 1 [Homo (345 aa) initn: 331 init1: 331 opt: 352 Z-score: 459.3 bits: 92.3 E(85289): 7.6e-19 Smith-Waterman score: 352; 40.5% identity (75.4% similar) in 126 aa overlap (9-134:1-124) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : :: .:..:. : : .. . ..:...:. :.. : ..:. ::.:::: NP_005 MQLEIQVALNFIISYLYNK--LPRRRVNIFGEELERLLKKKYEGHWYPEKPY 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC ::::.:::.:..:.::.: ..... ::. ... ::..:..:.::.::::.::: : . NP_005 KGSGFRCIHIGEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVK 60 70 80 90 100 110 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS ::: . .: : NP_005 VLYVDDNNENGCELDKEIKNSFNPEAQVFMPISDPASSVSSSPSPPFGHSAAVSPTFMPR 120 130 140 150 160 170 >>NP_057356 (OMIM: 607396) protein Tob2 [Homo sapiens] (344 aa) initn: 311 init1: 311 opt: 336 Z-score: 438.6 bits: 88.5 E(85289): 1.1e-17 Smith-Waterman score: 336; 39.2% identity (73.6% similar) in 125 aa overlap (9-133:1-121) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : :: .:..:. : : .. . ..: .:. :.. : ..:. ::.:::: NP_057 MQLEIKVALNFIISYLYNK--LPRRRADLFGEELERLLKKKYEGHWYPEKPL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC ::::.::..:.. .::.. .:.. ::. ... .: ::..:.::.::::.::: :.. NP_057 KGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVK 60 70 80 90 100 110 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS ::: . . .:: NP_057 VLYLDD--SEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIP 120 130 140 150 160 >>XP_016884028 (OMIM: 607396) PREDICTED: protein Tob2 is (344 aa) initn: 311 init1: 311 opt: 336 Z-score: 438.6 bits: 88.5 E(85289): 1.1e-17 Smith-Waterman score: 336; 39.2% identity (73.6% similar) in 125 aa overlap (9-133:1-121) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : :: .:..:. : : .. . ..: .:. :.. : ..:. ::.:::: XP_016 MQLEIKVALNFIISYLYNK--LPRRRADLFGEELERLLKKKYEGHWYPEKPL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC ::::.::..:.. .::.. .:.. ::. ... .: ::..:.::.::::.::: :.. XP_016 KGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVK 60 70 80 90 100 110 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS ::: . . .:: XP_016 VLYLDD--SEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIP 120 130 140 150 160 >>XP_005261372 (OMIM: 607396) PREDICTED: protein Tob2 is (344 aa) initn: 311 init1: 311 opt: 336 Z-score: 438.6 bits: 88.5 E(85289): 1.1e-17 Smith-Waterman score: 336; 39.2% identity (73.6% similar) in 125 aa overlap (9-133:1-121) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : :: .:..:. : : .. . ..: .:. :.. : ..:. ::.:::: XP_005 MQLEIKVALNFIISYLYNK--LPRRRADLFGEELERLLKKKYEGHWYPEKPL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC ::::.::..:.. .::.. .:.. ::. ... .: ::..:.::.::::.::: :.. XP_005 KGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVK 60 70 80 90 100 110 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS ::: . . .:: XP_005 VLYLDD--SEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIP 120 130 140 150 160 >>XP_006724168 (OMIM: 607396) PREDICTED: protein Tob2 is (344 aa) initn: 311 init1: 311 opt: 336 Z-score: 438.6 bits: 88.5 E(85289): 1.1e-17 Smith-Waterman score: 336; 39.2% identity (73.6% similar) in 125 aa overlap (9-133:1-121) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : :: .:..:. : : .. . ..: .:. :.. : ..:. ::.:::: XP_006 MQLEIKVALNFIISYLYNK--LPRRRADLFGEELERLLKKKYEGHWYPEKPL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSIC ::::.::..:.. .::.. .:.. ::. ... .: ::..:.::.::::.::: :.. XP_006 KGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVK 60 70 80 90 100 110 130 140 150 pF1KB8 VLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS ::: . . .:: XP_006 VLYLDD--SEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIP 120 130 140 150 160 >>NP_006797 (OMIM: 605674) protein BTG3 isoform b [Homo (252 aa) initn: 255 init1: 255 opt: 291 Z-score: 382.5 bits: 77.6 E(85289): 1.5e-14 Smith-Waterman score: 291; 41.4% identity (69.0% similar) in 116 aa overlap (9-122:1-114) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : ::::.: :.. :.: . .... .. :. : : :.::.::.::::: NP_006 MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPS 10 20 30 40 50 70 80 90 100 110 pF1KB8 KGSGYRCIRIN--HKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGS ::..:::::.: ...:: . .. . . .: ::.:::::::: :: : :: .. NP_006 KGQAYRCIRVNKFQRVDPDVLKACENSCILYSDLG--LPKELTLWVDPCEVCCRYGEKNN 60 70 80 90 100 110 120 130 140 150 pF1KB8 ICVLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS .. NP_006 AFIVASFENKDENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASP 120 130 140 150 160 170 >>XP_016883755 (OMIM: 605674) PREDICTED: protein BTG3 is (252 aa) initn: 255 init1: 255 opt: 291 Z-score: 382.5 bits: 77.6 E(85289): 1.5e-14 Smith-Waterman score: 291; 41.4% identity (69.0% similar) in 116 aa overlap (9-122:1-114) 10 20 30 40 50 60 pF1KB8 MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPS : ::::.: :.. :.: . .... .. :. : : :.::.::.::::: XP_016 MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPS 10 20 30 40 50 70 80 90 100 110 pF1KB8 KGSGYRCIRIN--HKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGS ::..:::::.: ...:: . .. . . .: ::.:::::::: :: : :: .. XP_016 KGQAYRCIRVNKFQRVDPDVLKACENSCILYSDLG--LPKELTLWVDPCEVCCRYGEKNN 60 70 80 90 100 110 120 130 140 150 pF1KB8 ICVLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS .. XP_016 AFIVASFENKDENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASP 120 130 140 150 160 170 158 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:45:24 2016 done: Sat Nov 5 00:45:25 2016 Total Scan time: 4.980 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]