FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8873, 162 aa 1>>>pF1KB8873 162 - 162 aa - 162 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0203+/-0.000328; mu= 6.0317+/- 0.021 mean_var=147.7242+/-28.473, 0's: 0 Z-trim(120.5): 38 B-trim: 52 in 2/53 Lambda= 0.105523 statistics sampled from 35789 (35831) to 35789 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.42), width: 16 Scan time: 6.190 The best scores are: opt bits E(85289) NP_002350 (OMIM: 602020) transcription factor MafG ( 162) 998 162.3 3e-40 NP_116100 (OMIM: 602020) transcription factor MafG ( 162) 998 162.3 3e-40 XP_011521880 (OMIM: 602020) PREDICTED: transcripti ( 162) 998 162.3 3e-40 XP_005249908 (OMIM: 600197) PREDICTED: transcripti ( 156) 675 113.2 1.9e-25 XP_006715836 (OMIM: 600197) PREDICTED: transcripti ( 156) 675 113.2 1.9e-25 NP_002351 (OMIM: 600197) transcription factor MafK ( 156) 675 113.2 1.9e-25 NP_001155044 (OMIM: 604877) transcription factor M ( 164) 547 93.7 1.4e-19 NP_036455 (OMIM: 604877) transcription factor MafF ( 164) 547 93.7 1.4e-19 NP_001155045 (OMIM: 604877) transcription factor M ( 164) 547 93.7 1.4e-19 NP_001155046 (OMIM: 604877) transcription factor M ( 135) 469 81.7 4.6e-16 NP_005452 (OMIM: 166300,608968,617041) transcripti ( 323) 368 66.7 3.8e-11 NP_001026974 (OMIM: 177075,601088,610202) transcri ( 373) 348 63.7 3.4e-10 XP_016878723 (OMIM: 177075,601088,610202) PREDICTE ( 383) 348 63.7 3.5e-10 XP_016878722 (OMIM: 177075,601088,610202) PREDICTE ( 383) 348 63.7 3.5e-10 XP_016878724 (OMIM: 177075,601088,610202) PREDICTE ( 383) 348 63.7 3.5e-10 NP_005351 (OMIM: 177075,601088,610202) transcripti ( 403) 348 63.7 3.6e-10 NP_963883 (OMIM: 610303) transcription factor MafA ( 353) 344 63.1 5e-10 XP_016876839 (OMIM: 162080,613750) PREDICTED: neur ( 132) 278 52.7 2.6e-07 XP_011535108 (OMIM: 162080,613750) PREDICTED: neur ( 234) 278 52.9 3.9e-07 XP_005267766 (OMIM: 162080,613750) PREDICTED: neur ( 237) 278 52.9 4e-07 XP_005267767 (OMIM: 162080,613750) PREDICTED: neur ( 237) 278 52.9 4e-07 XP_011535106 (OMIM: 162080,613750) PREDICTED: neur ( 237) 278 52.9 4e-07 XP_011535107 (OMIM: 162080,613750) PREDICTED: neur ( 237) 278 52.9 4e-07 XP_011535104 (OMIM: 162080,613750) PREDICTED: neur ( 237) 278 52.9 4e-07 XP_005267765 (OMIM: 162080,613750) PREDICTED: neur ( 237) 278 52.9 4e-07 NP_006168 (OMIM: 162080,613750) neural retina-spec ( 237) 278 52.9 4e-07 XP_011535103 (OMIM: 162080,613750) PREDICTED: neur ( 339) 278 53.0 5.2e-07 >>NP_002350 (OMIM: 602020) transcription factor MafG [Ho (162 aa) initn: 998 init1: 998 opt: 998 Z-score: 843.5 bits: 162.3 E(85289): 3e-40 Smith-Waterman score: 998; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS :::::::::::::::::::::::::::::::::::::::::: NP_002 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS 130 140 150 160 >>NP_116100 (OMIM: 602020) transcription factor MafG [Ho (162 aa) initn: 998 init1: 998 opt: 998 Z-score: 843.5 bits: 162.3 E(85289): 3e-40 Smith-Waterman score: 998; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS :::::::::::::::::::::::::::::::::::::::::: NP_116 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS 130 140 150 160 >>XP_011521880 (OMIM: 602020) PREDICTED: transcription f (162 aa) initn: 998 init1: 998 opt: 998 Z-score: 843.5 bits: 162.3 E(85289): 3e-40 Smith-Waterman score: 998; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS :::::::::::::::::::::::::::::::::::::::::: XP_011 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS 130 140 150 160 >>XP_005249908 (OMIM: 600197) PREDICTED: transcription f (156 aa) initn: 675 init1: 675 opt: 675 Z-score: 578.0 bits: 113.2 E(85289): 1.9e-25 Smith-Waterman score: 694; 75.0% identity (86.5% similar) in 156 aa overlap (1-156:1-142) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK ::: : :::::::.: :::. :.:.:::.:::::::::::::.:::...::::::::: XP_005 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART :::::::::.::::::::::.:..:::::::::: ::.::.::::::::::::::::::: XP_005 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS :::.::::. :::.::::::::: XP_005 VARGPVAPS--------------KVATTSVITIVKSTELSSTSVPFSAAS 130 140 150 >>XP_006715836 (OMIM: 600197) PREDICTED: transcription f (156 aa) initn: 675 init1: 675 opt: 675 Z-score: 578.0 bits: 113.2 E(85289): 1.9e-25 Smith-Waterman score: 694; 75.0% identity (86.5% similar) in 156 aa overlap (1-156:1-142) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK ::: : :::::::.: :::. :.:.:::.:::::::::::::.:::...::::::::: XP_006 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART :::::::::.::::::::::.:..:::::::::: ::.::.::::::::::::::::::: XP_006 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS :::.::::. :::.::::::::: XP_006 VARGPVAPS--------------KVATTSVITIVKSTELSSTSVPFSAAS 130 140 150 >>NP_002351 (OMIM: 600197) transcription factor MafK [Ho (156 aa) initn: 675 init1: 675 opt: 675 Z-score: 578.0 bits: 113.2 E(85289): 1.9e-25 Smith-Waterman score: 694; 75.0% identity (86.5% similar) in 156 aa overlap (1-156:1-142) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK ::: : :::::::.: :::. :.:.:::.:::::::::::::.:::...::::::::: NP_002 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART :::::::::.::::::::::.:..:::::::::: ::.::.::::::::::::::::::: NP_002 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS :::.::::. :::.::::::::: NP_002 VARGPVAPS--------------KVATTSVITIVKSTELSSTSVPFSAAS 130 140 150 >>NP_001155044 (OMIM: 604877) transcription factor MafF (164 aa) initn: 568 init1: 532 opt: 547 Z-score: 472.4 bits: 93.7 E(85289): 1.4e-19 Smith-Waterman score: 564; 65.4% identity (80.1% similar) in 156 aa overlap (1-156:1-142) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK :.. ..::::.::: .:: :.:: :. .::::::.:::::: ::...::::::::: NP_001 MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART ::::::::::::: :::::.:::.::..::.::: :::.:.:::::::.: :::: :::. NP_001 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS : : :::: : : :: .:::::::: NP_001 V-----AAARGP--ATL-------VAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 130 140 150 160 >>NP_036455 (OMIM: 604877) transcription factor MafF iso (164 aa) initn: 568 init1: 532 opt: 547 Z-score: 472.4 bits: 93.7 E(85289): 1.4e-19 Smith-Waterman score: 564; 65.4% identity (80.1% similar) in 156 aa overlap (1-156:1-142) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK :.. ..::::.::: .:: :.:: :. .::::::.:::::: ::...::::::::: NP_036 MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART ::::::::::::: :::::.:::.::..::.::: :::.:.:::::::.: :::: :::. NP_036 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS : : :::: : : :: .:::::::: NP_036 V-----AAARGP--ATL-------VAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 130 140 150 160 >>NP_001155045 (OMIM: 604877) transcription factor MafF (164 aa) initn: 568 init1: 532 opt: 547 Z-score: 472.4 bits: 93.7 E(85289): 1.4e-19 Smith-Waterman score: 564; 65.4% identity (80.1% similar) in 156 aa overlap (1-156:1-142) 10 20 30 40 50 60 pF1KB8 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK :.. ..::::.::: .:: :.:: :. .::::::.:::::: ::...::::::::: NP_001 MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART ::::::::::::: :::::.:::.::..::.::: :::.:.:::::::.: :::: :::. NP_001 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 70 80 90 100 110 120 130 140 150 160 pF1KB8 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS : : :::: : : :: .:::::::: NP_001 V-----AAARGP--ATL-------VAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 130 140 150 160 >>NP_001155046 (OMIM: 604877) transcription factor MafF (135 aa) initn: 493 init1: 457 opt: 469 Z-score: 409.3 bits: 81.7 E(85289): 4.6e-16 Smith-Waterman score: 486; 70.4% identity (82.4% similar) in 125 aa overlap (32-156:3-113) 10 20 30 40 50 60 pF1KB8 TTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKN .::::::.:::::: ::...:::::::::: NP_001 MGLSVRELNRHLRGLSAEEVTRLKQRRRTLKN 10 20 30 70 80 90 100 110 120 pF1KB8 RGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTV :::::::::::: :::::.:::.::..::.::: :::.:.:::::::.: :::: :::.: NP_001 RGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSV 40 50 60 70 80 90 130 140 150 160 pF1KB8 ARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS : :::: : : :: .:::::::: NP_001 A-----AARGP--ATL-------VAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 100 110 120 130 162 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:16:17 2016 done: Fri Nov 4 16:16:18 2016 Total Scan time: 6.190 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]