FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8875, 166 aa 1>>>pF1KB8875 166 - 166 aa - 166 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2661+/-0.000904; mu= 6.7154+/- 0.053 mean_var=97.9281+/-20.129, 0's: 0 Z-trim(108.0): 231 B-trim: 71 in 2/48 Lambda= 0.129605 statistics sampled from 9610 (9901) to 9610 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.304), width: 16 Scan time: 1.970 The best scores are: opt bits E(32554) CCDS12244.1 CDKN2D gene_id:1032|Hs108|chr19 ( 166) 1064 209.0 1.1e-54 CCDS555.1 CDKN2C gene_id:1031|Hs108|chr1 ( 168) 437 91.8 2.2e-19 CCDS6512.1 CDKN2B gene_id:1030|Hs108|chr9 ( 138) 342 74.0 4.1e-14 CCDS6510.1 CDKN2A gene_id:1029|Hs108|chr9 ( 156) 338 73.2 7.6e-14 CCDS56565.1 CDKN2A gene_id:1029|Hs108|chr9 ( 167) 332 72.1 1.7e-13 >>CCDS12244.1 CDKN2D gene_id:1032|Hs108|chr19 (166 aa) initn: 1064 init1: 1064 opt: 1064 Z-score: 1095.3 bits: 209.0 E(32554): 1.1e-54 Smith-Waterman score: 1064; 100.0% identity (100.0% similar) in 166 aa overlap (1-166:1-166) 10 20 30 40 50 60 pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT 70 80 90 100 110 120 130 140 150 160 pF1KB8 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL :::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 130 140 150 160 >>CCDS555.1 CDKN2C gene_id:1031|Hs108|chr1 (168 aa) initn: 465 init1: 330 opt: 437 Z-score: 461.6 bits: 91.8 E(32554): 2.2e-19 Smith-Waterman score: 437; 45.8% identity (77.4% similar) in 155 aa overlap (9-161:6-159) 10 20 30 40 50 60 pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL :..:..::::::.... ::. . :. .: : ::.:::::: .:. :: .: CCDS55 MAEPWGNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT : .::.:...: .: . .:::::.::::::..:.: ::::. :. : ::.:::..::: CCDS55 LLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHL 60 70 80 90 100 110 130 140 150 160 pF1KB8 AVVSFLAAE--SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL :: ::. . :.. .:. .: : .:: : ...:...:.. CCDS55 RVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 120 130 140 150 160 >>CCDS6512.1 CDKN2B gene_id:1030|Hs108|chr9 (138 aa) initn: 373 init1: 209 opt: 342 Z-score: 366.9 bits: 74.0 E(32554): 4.1e-14 Smith-Waterman score: 342; 51.7% identity (75.0% similar) in 116 aa overlap (12-126:18-132) 10 20 30 40 50 pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST :..::::: :..::.::. . :...::::. :.::::.::. CCDS65 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLE-AGADPNGVNRFGRRAIQVMMMGSA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 AIALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL .: :: .:: :: : . : ::::::: :::::: :: . :: ..: :. : ::. : CCDS65 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 60 70 80 90 100 110 120 130 140 150 160 pF1KB8 AVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL : ..:: :...: CCDS65 AEERGHRDVAGYLRTATGD 120 130 >>CCDS6510.1 CDKN2A gene_id:1029|Hs108|chr9 (156 aa) initn: 303 init1: 218 opt: 338 Z-score: 362.1 bits: 73.2 E(32554): 7.6e-14 Smith-Waterman score: 338; 44.0% identity (64.7% similar) in 150 aa overlap (8-156:12-156) 10 20 30 40 50 pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAI ..: :. ::::: :.::: ::. . :.: : .:. .::::.::. . CCDS65 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARV 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 ALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV : :: .:: :: : . : ::::::: :::::: :: . :: ..: :. : ::. :: CCDS65 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE 60 70 80 90 100 110 120 130 140 150 160 pF1KB8 QEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL . :: :. .: : . .:: . .. .: .:. : CCDS65 ELGHRDVARYLRAAAG----GTRGSNHARIDAAEGPSDIPD 120 130 140 150 >>CCDS56565.1 CDKN2A gene_id:1029|Hs108|chr9 (167 aa) initn: 303 init1: 218 opt: 332 Z-score: 355.6 bits: 72.1 E(32554): 1.7e-13 Smith-Waterman score: 332; 43.0% identity (65.1% similar) in 149 aa overlap (8-155:12-155) 10 20 30 40 50 pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAI ..: :. ::::: :.::: ::. . :.: : .:. .::::.::. . CCDS56 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARV 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 ALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV : :: .:: :: : . : ::::::: :::::: :: . :: ..: :. : ::. :: CCDS56 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE 60 70 80 90 100 110 120 130 140 150 160 pF1KB8 QEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL . :: :. .: : . .:: . .. .: .... CCDS56 ELGHRDVARYLRAAAG----GTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA 120 130 140 150 160 166 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:19:39 2016 done: Fri Nov 4 20:19:39 2016 Total Scan time: 1.970 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]