FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8876, 167 aa 1>>>pF1KB8876 167 - 167 aa - 167 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4296+/-0.000347; mu= 11.5423+/- 0.021 mean_var=63.5234+/-12.943, 0's: 0 Z-trim(114.4): 17 B-trim: 159 in 1/51 Lambda= 0.160919 statistics sampled from 24228 (24245) to 24228 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.284), width: 16 Scan time: 5.070 The best scores are: opt bits E(85289) NP_000221 (OMIM: 164160,614962) leptin precursor [ ( 167) 1112 266.4 1.5e-71 XP_005250397 (OMIM: 164160,614962) PREDICTED: lept ( 166) 1093 262.0 3.1e-70 >>NP_000221 (OMIM: 164160,614962) leptin precursor [Homo (167 aa) initn: 1112 init1: 1112 opt: 1112 Z-score: 1405.7 bits: 266.4 E(85289): 1.5e-71 Smith-Waterman score: 1112; 100.0% identity (100.0% similar) in 167 aa overlap (1-167:1-167) 10 20 30 40 50 60 pF1KB8 MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLP 70 80 90 100 110 120 130 140 150 160 pF1KB8 WASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC ::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC 130 140 150 160 >>XP_005250397 (OMIM: 164160,614962) PREDICTED: leptin i (166 aa) initn: 765 init1: 765 opt: 1093 Z-score: 1381.9 bits: 262.0 E(85289): 3.1e-70 Smith-Waterman score: 1093; 99.4% identity (99.4% similar) in 167 aa overlap (1-167:1-166) 10 20 30 40 50 60 pF1KB8 MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGL :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_005 MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHT-SVSSKQKVTGL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 DFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLP 60 70 80 90 100 110 130 140 150 160 pF1KB8 WASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC ::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC 120 130 140 150 160 167 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:16:49 2016 done: Fri Nov 4 16:16:50 2016 Total Scan time: 5.070 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]