FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8877, 168 aa 1>>>pF1KB8877 168 - 168 aa - 168 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1885+/-0.00102; mu= 6.7738+/- 0.059 mean_var=97.1679+/-20.884, 0's: 0 Z-trim(105.9): 236 B-trim: 334 in 2/48 Lambda= 0.130111 statistics sampled from 8378 (8669) to 8378 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.266), width: 16 Scan time: 1.850 The best scores are: opt bits E(32554) CCDS555.1 CDKN2C gene_id:1031|Hs108|chr1 ( 168) 1092 215.3 1.4e-56 CCDS12244.1 CDKN2D gene_id:1032|Hs108|chr19 ( 166) 437 92.3 1.5e-19 CCDS56565.1 CDKN2A gene_id:1029|Hs108|chr9 ( 167) 314 69.2 1.3e-12 CCDS6510.1 CDKN2A gene_id:1029|Hs108|chr9 ( 156) 311 68.7 1.8e-12 CCDS6512.1 CDKN2B gene_id:1030|Hs108|chr9 ( 138) 298 66.2 9e-12 >>CCDS555.1 CDKN2C gene_id:1031|Hs108|chr1 (168 aa) initn: 1092 init1: 1092 opt: 1092 Z-score: 1129.1 bits: 215.3 E(32554): 1.4e-56 Smith-Waterman score: 1092; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168) 10 20 30 40 50 60 pF1KB8 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 70 80 90 100 110 120 130 140 150 160 pF1KB8 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 130 140 150 160 >>CCDS12244.1 CDKN2D gene_id:1032|Hs108|chr19 (166 aa) initn: 494 init1: 330 opt: 437 Z-score: 464.7 bits: 92.3 E(32554): 1.5e-19 Smith-Waterman score: 437; 45.8% identity (77.4% similar) in 155 aa overlap (6-159:9-161) 10 20 30 40 50 pF1KB8 MAEPWGNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRL :..:..::::::.... ::. . :. .: : ::.:::::: .:. :: .: CCDS12 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHL : .::.:...: .: . .:::::.::::::..:.: ::::. :. : ::.:::..::: CCDS12 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 RVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ :: ::. . :.. .:. .: : .:: : ...:...:.. CCDS12 AVVSFLAAE--SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 130 140 150 160 >>CCDS56565.1 CDKN2A gene_id:1029|Hs108|chr9 (167 aa) initn: 312 init1: 181 opt: 314 Z-score: 339.9 bits: 69.2 E(32554): 1.3e-12 Smith-Waterman score: 314; 38.1% identity (69.4% similar) in 147 aa overlap (3-148:10-156) 10 20 30 40 50 pF1KB8 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIA :: .. ::.::::: .:.. .::. .. :: :..:: .::: .:. ..: CCDS56 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 RRLLLRGANPDLKDRTGFAV-IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAK . :::.::.:. : . .. .::::: :::::: .: . : ....: : ::. :: . CCDS56 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 EGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ :: :...: .... : . . :.: ... : CCDS56 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA 130 140 150 160 >>CCDS6510.1 CDKN2A gene_id:1029|Hs108|chr9 (156 aa) initn: 312 init1: 181 opt: 311 Z-score: 337.2 bits: 68.7 E(32554): 1.8e-12 Smith-Waterman score: 311; 39.6% identity (70.5% similar) in 139 aa overlap (3-140:10-148) 10 20 30 40 50 pF1KB8 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIA :: .. ::.::::: .:.. .::. .. :: :..:: .::: .:. ..: CCDS65 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 RRLLLRGANPDLKDRTGFAV-IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAK . :::.::.:. : . .. .::::: :::::: .: . : ....: : ::. :: . CCDS65 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 EGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ :: :...: .... : . . :.: CCDS65 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD 130 140 150 >>CCDS6512.1 CDKN2B gene_id:1030|Hs108|chr9 (138 aa) initn: 310 init1: 176 opt: 298 Z-score: 324.8 bits: 66.2 E(32554): 9e-12 Smith-Waterman score: 298; 45.2% identity (73.9% similar) in 115 aa overlap (9-122:18-132) 10 20 30 40 50 pF1KB8 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPE :::::::: .:.. .::. ... :. : ::: :.::: .:. . CCDS65 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSAR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 IARRLLLRGANPDLKDRTGFAV-IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA .:. :::.::.:. : . .. .::::: :::::: .: . : ....: : ::. :: CCDS65 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ ..:: :. .: CCDS65 EERGHRDVAGYLRTATGD 130 168 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:57:20 2016 done: Sat Nov 5 19:57:20 2016 Total Scan time: 1.850 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]