FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8882, 182 aa 1>>>pF1KB8882 182 - 182 aa - 182 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9195+/-0.000546; mu= 15.3586+/- 0.033 mean_var=61.0611+/-12.268, 0's: 0 Z-trim(113.0): 16 B-trim: 10 in 1/50 Lambda= 0.164131 statistics sampled from 13638 (13654) to 13638 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.419), width: 16 Scan time: 2.070 The best scores are: opt bits E(32554) CCDS8352.1 HSPB2 gene_id:3316|Hs108|chr11 ( 182) 1230 298.7 1.3e-81 CCDS8351.1 CRYAB gene_id:1410|Hs108|chr11 ( 175) 381 97.6 4.3e-21 CCDS12475.1 HSPB6 gene_id:126393|Hs108|chr19 ( 160) 349 90.0 7.6e-19 CCDS82651.1 LOC102724652 gene_id:102724652|Hs108|c ( 173) 324 84.1 4.9e-17 CCDS13695.1 CRYAA gene_id:1409|Hs108|chr21 ( 173) 324 84.1 4.9e-17 CCDS5583.1 HSPB1 gene_id:3315|Hs108|chr7 ( 205) 309 80.6 6.6e-16 CCDS81626.1 CRYAB gene_id:1410|Hs108|chr11 ( 108) 293 76.6 5.4e-15 CCDS82652.1 LOC102724652 gene_id:102724652|Hs108|c ( 136) 277 72.9 9.1e-14 CCDS3961.1 HSPB3 gene_id:8988|Hs108|chr5 ( 150) 240 64.2 4.3e-11 >>CCDS8352.1 HSPB2 gene_id:3316|Hs108|chr11 (182 aa) initn: 1230 init1: 1230 opt: 1230 Z-score: 1578.4 bits: 298.7 E(32554): 1.3e-81 Smith-Waterman score: 1230; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182) 10 20 30 40 50 60 pF1KB8 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV 130 140 150 160 170 180 pF1KB8 EP :: CCDS83 EP >>CCDS8351.1 CRYAB gene_id:1410|Hs108|chr11 (175 aa) initn: 358 init1: 310 opt: 381 Z-score: 492.2 bits: 97.6 E(32554): 4.3e-21 Smith-Waterman score: 381; 43.1% identity (72.3% similar) in 137 aa overlap (16-148:15-149) 10 20 30 40 50 pF1KB8 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEIL-TPTLYHGYYVRPRA---APA . : .:::: .: ::: :: ... : : .:.:: . ::. CCDS83 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPS 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSRE . : ::.:: . .:.. :::.::.:.:. :... ...:: ..: .: :.:::.::: CCDS83 WFDT--GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISRE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEE : : : .:::::: . ..:: ::.:....:: CCDS83 FHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK 120 130 140 150 160 170 180 pF1KB8 AAIVEP >>CCDS12475.1 HSPB6 gene_id:126393|Hs108|chr19 (160 aa) initn: 339 init1: 253 opt: 349 Z-score: 451.8 bits: 90.0 E(32554): 7.6e-19 Smith-Waterman score: 349; 45.0% identity (71.0% similar) in 131 aa overlap (18-146:22-146) 10 20 30 40 50 pF1KB8 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEI--LTPTLYHGYYVRPRAA .. :.:: .:::::::: :. : :: ::.: : CCDS12 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLR---A 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PAGEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVS :. .... . :.:...:::.::.:.:..:..: . .:: ::: .: :.::::. CCDS12 PS---VALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 REFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEE ::: : : :: ::: : .::: .:.:...: CCDS12 REFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK 120 130 140 150 160 180 pF1KB8 EEAAIVEP >>CCDS82651.1 LOC102724652 gene_id:102724652|Hs108|chr21 (173 aa) initn: 336 init1: 279 opt: 324 Z-score: 419.3 bits: 84.1 E(32554): 4.9e-17 Smith-Waterman score: 324; 38.0% identity (62.0% similar) in 158 aa overlap (21-178:19-170) 10 20 30 40 50 60 pF1KB8 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS :::: .: :::::. ..: : : : . CCDS82 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLL-PFLSSTISPYYRQSLFRTVL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT .: ::.: .. :: ::::.::.:...::.. :...:. ..: .: : ::..:::: : CCDS82 DSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV : ::..:: . .:: ::.:.. .:. ::. : : : . ::. .: CCDS82 YRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAI-----PVSREEKPTSAPS 120 130 140 150 160 170 pF1KB8 EP CCDS82 S >>CCDS13695.1 CRYAA gene_id:1409|Hs108|chr21 (173 aa) initn: 336 init1: 279 opt: 324 Z-score: 419.3 bits: 84.1 E(32554): 4.9e-17 Smith-Waterman score: 324; 38.0% identity (62.0% similar) in 158 aa overlap (21-178:19-170) 10 20 30 40 50 60 pF1KB8 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS :::: .: :::::. ..: : : : . CCDS13 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLL-PFLSSTISPYYRQSLFRTVL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT .: ::.: .. :: ::::.::.:...::.. :...:. ..: .: : ::..:::: : CCDS13 DSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV : ::..:: . .:: ::.:.. .:. ::. : : : . ::. .: CCDS13 YRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAI-----PVSREEKPTSAPS 120 130 140 150 160 170 pF1KB8 EP CCDS13 S >>CCDS5583.1 HSPB1 gene_id:3315|Hs108|chr7 (205 aa) initn: 351 init1: 294 opt: 309 Z-score: 399.0 bits: 80.6 E(32554): 6.6e-16 Smith-Waterman score: 341; 37.2% identity (58.9% similar) in 207 aa overlap (1-178:1-204) 10 20 30 40 50 pF1KB8 MSGRSVPHA---HPATAEYEFANP-SRLGEQRFGEGLLPEEI---LTPTLYHGYYVRPRA :. : :: . :. .. : ::: .: :: :::: : . . :: ::: CCDS55 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGY-VRPLP 10 20 30 40 50 60 70 80 90 pF1KB8 APAGEG--------SRA-------GASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLE : :. ::: :.::.: . .... :::.::.:::.::.: :...: CCDS55 PAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVE 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB8 VSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVN ....: .: :.::..:: : : :.:: ::: .: ..:: .: :..::: .: :. : CCDS55 ITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMP--KLATQSN 120 130 140 150 160 170 160 170 180 pF1KB8 EVYISL-------LPAPPDPEEEEEAAIVEP :. : . : .: . .: :: CCDS55 EITIPVTFESRAQLGGPEAAKSDETAAK 180 190 200 >>CCDS81626.1 CRYAB gene_id:1410|Hs108|chr11 (108 aa) initn: 293 init1: 293 opt: 293 Z-score: 382.6 bits: 76.6 E(32554): 5.4e-15 Smith-Waterman score: 293; 46.3% identity (81.7% similar) in 82 aa overlap (67-148:1-82) 40 50 60 70 80 90 pF1KB8 EILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNL .:: . .:.. :::.::.:.:. :... .. CCDS81 MRLEKDRFSVNLDVKHFSPEELKVKVLGDV 10 20 30 100 110 120 130 140 150 pF1KB8 LEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTE .:: ..: .: :.:::.:::: : : .:::::: . ..:: ::.:....:: CCDS81 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPER 40 50 60 70 80 90 160 170 180 pF1KB8 VNEVYISLLPAPPDPEEEEEAAIVEP CCDS81 TIPITREEKPAVTAAPKK 100 >>CCDS82652.1 LOC102724652 gene_id:102724652|Hs108|chr21 (136 aa) initn: 262 init1: 262 opt: 277 Z-score: 360.7 bits: 72.9 E(32554): 9.1e-14 Smith-Waterman score: 277; 37.5% identity (64.8% similar) in 128 aa overlap (51-178:12-133) 30 40 50 60 70 80 pF1KB8 PSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLDV :.: : .: : ..: .. :: :::: CCDS82 MPVCPGDSHRPPKALPHLVCGRRG-RQVRSDRDKFVIFLDV 10 20 30 40 90 100 110 120 130 140 pF1KB8 SHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDG .::.:...::.. :...:. ..: .: : ::..:::: : : ::..:: . .:: :: CCDS82 KHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADG 50 60 70 80 90 100 150 160 170 180 pF1KB8 ILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP .:.. .:. ::. : : : . ::. .: CCDS82 MLTFCGPKIQTGLDATHAERAI-----PVSREEKPTSAPSS 110 120 130 >>CCDS3961.1 HSPB3 gene_id:8988|Hs108|chr5 (150 aa) initn: 257 init1: 236 opt: 240 Z-score: 312.7 bits: 64.2 E(32554): 4.3e-11 Smith-Waterman score: 240; 37.5% identity (66.3% similar) in 104 aa overlap (50-151:47-150) 20 30 40 50 60 70 pF1KB8 NPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLD . ::: . . :. . : ....:: .:: CCDS39 QEEFEARGLEDCRLDHALYALPGPTIVDLRKTRAAQSPPVDSAAETPPREGKSHFQILLD 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB8 VSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHD : .: :... ..: .. : ..:.: :.:.:::.:: : : : :: :. . :.: :: CCDS39 VVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVEIKDLSAVLCHD 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GILNLEA--PRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP ::: .:. : : . CCDS39 GILVVEVKDPVGTK 140 150 182 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:58:22 2016 done: Sat Nov 5 19:58:22 2016 Total Scan time: 2.070 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]