Result of FASTA (omim) for pF1KB8885
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8885, 193 aa
  1>>>pF1KB8885 193 - 193 aa - 193 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4185+/-0.000298; mu= -4.0374+/- 0.019
 mean_var=205.3358+/-43.351, 0's: 0 Z-trim(123.6): 9  B-trim: 1992 in 1/56
 Lambda= 0.089504
 statistics sampled from 43697 (43712) to 43697 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.513), width:  16
 Scan time:  6.300

The best scores are:                                      opt bits E(85289)
NP_001138358 (OMIM: 300149) cbp/p300-interacting t ( 193) 1281 176.5 2.3e-44
NP_001138359 (OMIM: 300149) cbp/p300-interacting t ( 193) 1281 176.5 2.3e-44
NP_004134 (OMIM: 300149) cbp/p300-interacting tran ( 193) 1281 176.5 2.3e-44
XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-in ( 219) 1281 176.5 2.6e-44
NP_001138357 (OMIM: 300149) cbp/p300-interacting t ( 219) 1281 176.5 2.6e-44
NP_001161860 (OMIM: 602937,614431,614433) cbp/p300 ( 270)  258 44.5 0.00018
NP_006070 (OMIM: 602937,614431,614433) cbp/p300-in ( 270)  258 44.5 0.00018
NP_001161861 (OMIM: 602937,614431,614433) cbp/p300 ( 275)  258 44.5 0.00018
NP_597724 (OMIM: 606815) cbp/p300-interacting tran ( 184)  254 43.9 0.00019


>>NP_001138358 (OMIM: 300149) cbp/p300-interacting trans  (193 aa)
 initn: 1281 init1: 1281 opt: 1281  Z-score: 917.4  bits: 176.5 E(85289): 2.3e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP
       :::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_001 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
              130       140       150       160       170       180

              190   
pF1KB8 NEFDFTADFPSSC
       :::::::::::::
NP_001 NEFDFTADFPSSC
              190   

>>NP_001138359 (OMIM: 300149) cbp/p300-interacting trans  (193 aa)
 initn: 1281 init1: 1281 opt: 1281  Z-score: 917.4  bits: 176.5 E(85289): 2.3e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP
       :::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_001 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
              130       140       150       160       170       180

              190   
pF1KB8 NEFDFTADFPSSC
       :::::::::::::
NP_001 NEFDFTADFPSSC
              190   

>>NP_004134 (OMIM: 300149) cbp/p300-interacting transact  (193 aa)
 initn: 1281 init1: 1281 opt: 1281  Z-score: 917.4  bits: 176.5 E(85289): 2.3e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP
       :::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_004 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
              130       140       150       160       170       180

              190   
pF1KB8 NEFDFTADFPSSC
       :::::::::::::
NP_004 NEFDFTADFPSSC
              190   

>>XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-intera  (219 aa)
 initn: 1281 init1: 1281 opt: 1281  Z-score: 916.6  bits: 176.5 E(85289): 2.6e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:27-219)

                                         10        20        30    
pF1KB8                           MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
                                 ::::::::::::::::::::::::::::::::::
XP_011 MEPSAQQLQLAASLPANLSNFCQGSEMPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB8 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
               70        80        90       100       110       120

          100       110       120       130       140       150    
pF1KB8 MQLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
              130       140       150       160       170       180

          160       170       180       190   
pF1KB8 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
       :::::::::::::::::::::::::::::::::::::::
XP_011 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
              190       200       210         

>>NP_001138357 (OMIM: 300149) cbp/p300-interacting trans  (219 aa)
 initn: 1281 init1: 1281 opt: 1281  Z-score: 916.6  bits: 176.5 E(85289): 2.6e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:27-219)

                                         10        20        30    
pF1KB8                           MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
                                 ::::::::::::::::::::::::::::::::::
NP_001 MEPSAQQLQLAASLPANLSNFCQGSEMPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB8 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
               70        80        90       100       110       120

          100       110       120       130       140       150    
pF1KB8 MQLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
              130       140       150       160       170       180

          160       170       180       190   
pF1KB8 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
       :::::::::::::::::::::::::::::::::::::::
NP_001 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
              190       200       210         

>>NP_001161860 (OMIM: 602937,614431,614433) cbp/p300-int  (270 aa)
 initn: 344 init1: 248 opt: 258  Z-score: 201.3  bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:89-259)

        20        30        40        50        60        70       
pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
                                     :..  :...  : :..:.:. . .      
NP_001 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
       60        70        80        90       100       110        

        80        90               100             110             
pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE
        .   :: :: ::          :. :..  :....        ...:::       :: 
NP_001 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG
      120       130       140       150       160       170        

       120       130          140             150       160        
pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD
       .:  ..   :.. .:. : :   :.. :. ::      .::.: .:::::::::.:.:::
NP_001 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD
      180       190       200       210       220       230        

      170       180       190          
pF1KB8 RANELPELWLGQNEFDFTADFPSSC       
       : .:::::::::::::: .::           
NP_001 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
      240       250       260       270

>>NP_006070 (OMIM: 602937,614431,614433) cbp/p300-intera  (270 aa)
 initn: 344 init1: 248 opt: 258  Z-score: 201.3  bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:89-259)

        20        30        40        50        60        70       
pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
                                     :..  :...  : :..:.:. . .      
NP_006 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
       60        70        80        90       100       110        

        80        90               100             110             
pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE
        .   :: :: ::          :. :..  :....        ...:::       :: 
NP_006 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG
      120       130       140       150       160       170        

       120       130          140             150       160        
pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD
       .:  ..   :.. .:. : :   :.. :. ::      .::.: .:::::::::.:.:::
NP_006 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD
      180       190       200       210       220       230        

      170       180       190          
pF1KB8 RANELPELWLGQNEFDFTADFPSSC       
       : .:::::::::::::: .::           
NP_006 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
      240       250       260       270

>>NP_001161861 (OMIM: 602937,614431,614433) cbp/p300-int  (275 aa)
 initn: 344 init1: 248 opt: 258  Z-score: 201.2  bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:94-264)

        20        30        40        50        60        70       
pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
                                     :..  :...  : :..:.:. . .      
NP_001 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
            70        80        90       100       110       120   

        80        90               100             110             
pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE
        .   :: :: ::          :. :..  :....        ...:::       :: 
NP_001 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG
           130       140       150       160       170       180   

       120       130          140             150       160        
pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD
       .:  ..   :.. .:. : :   :.. :. ::      .::.: .:::::::::.:.:::
NP_001 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD
           190       200       210       220       230       240   

      170       180       190          
pF1KB8 RANELPELWLGQNEFDFTADFPSSC       
       : .:::::::::::::: .::           
NP_001 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
           250       260       270     

>>NP_597724 (OMIM: 606815) cbp/p300-interacting transact  (184 aa)
 initn: 230 init1: 147 opt: 254  Z-score: 201.0  bits: 43.9 E(85289): 0.00019
Smith-Waterman score: 254; 34.5% identity (55.0% similar) in 171 aa overlap (36-192:14-176)

          10        20        30        40        50        60     
pF1KB8 RPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSS
                                     :.   ..:  : : .  .    .:   .:.
NP_597                  MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSG
                                10        20        30        40   

          70                   80           90       100       110 
pF1KB8 GSPIGSPTTTPPTK-----------PPS-FNLHPA--PHLLASMQLQKLNSQYQGMAAAT
         : :.:   :: .           ::: :.  ::  :   .  .:: . . : : ::: 
NP_597 LRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAP
            50        60        70        80        90       100   

             120       130       140       150       160       170 
pF1KB8 PGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRAN
       :. ::  ::      : : . . . .:   :.. . .:.. .:::.: :: .:::: :. 
NP_597 PNAPG--GPP-----GPQPAPSAA-APPPPAHALGGMDAELIDEEALTSLELELGLHRVR
             110            120        130       140       150     

             180       190          
pF1KB8 ELPELWLGQNEFDFTADFPSSC       
       :::::.:::.:::  .:. :.        
NP_597 ELPELFLGQSEFDCFSDLGSAPPAGSVSC
         160       170       180    




193 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:19:47 2016 done: Fri Nov  4 16:19:48 2016
 Total Scan time:  6.300 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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