FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8885, 193 aa 1>>>pF1KB8885 193 - 193 aa - 193 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4185+/-0.000298; mu= -4.0374+/- 0.019 mean_var=205.3358+/-43.351, 0's: 0 Z-trim(123.6): 9 B-trim: 1992 in 1/56 Lambda= 0.089504 statistics sampled from 43697 (43712) to 43697 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.513), width: 16 Scan time: 6.300 The best scores are: opt bits E(85289) NP_001138358 (OMIM: 300149) cbp/p300-interacting t ( 193) 1281 176.5 2.3e-44 NP_001138359 (OMIM: 300149) cbp/p300-interacting t ( 193) 1281 176.5 2.3e-44 NP_004134 (OMIM: 300149) cbp/p300-interacting tran ( 193) 1281 176.5 2.3e-44 XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-in ( 219) 1281 176.5 2.6e-44 NP_001138357 (OMIM: 300149) cbp/p300-interacting t ( 219) 1281 176.5 2.6e-44 NP_001161860 (OMIM: 602937,614431,614433) cbp/p300 ( 270) 258 44.5 0.00018 NP_006070 (OMIM: 602937,614431,614433) cbp/p300-in ( 270) 258 44.5 0.00018 NP_001161861 (OMIM: 602937,614431,614433) cbp/p300 ( 275) 258 44.5 0.00018 NP_597724 (OMIM: 606815) cbp/p300-interacting tran ( 184) 254 43.9 0.00019 >>NP_001138358 (OMIM: 300149) cbp/p300-interacting trans (193 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 917.4 bits: 176.5 E(85289): 2.3e-44 Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_001 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 130 140 150 160 170 180 190 pF1KB8 NEFDFTADFPSSC ::::::::::::: NP_001 NEFDFTADFPSSC 190 >>NP_001138359 (OMIM: 300149) cbp/p300-interacting trans (193 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 917.4 bits: 176.5 E(85289): 2.3e-44 Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_001 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 130 140 150 160 170 180 190 pF1KB8 NEFDFTADFPSSC ::::::::::::: NP_001 NEFDFTADFPSSC 190 >>NP_004134 (OMIM: 300149) cbp/p300-interacting transact (193 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 917.4 bits: 176.5 E(85289): 2.3e-44 Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_004 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 130 140 150 160 170 180 190 pF1KB8 NEFDFTADFPSSC ::::::::::::: NP_004 NEFDFTADFPSSC 190 >>XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-intera (219 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 916.6 bits: 176.5 E(85289): 2.6e-44 Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:27-219) 10 20 30 pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL :::::::::::::::::::::::::::::::::: XP_011 MEPSAQQLQLAASLPANLSNFCQGSEMPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 MQLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD 130 140 150 160 170 180 160 170 180 190 pF1KB8 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC ::::::::::::::::::::::::::::::::::::::: XP_011 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC 190 200 210 >>NP_001138357 (OMIM: 300149) cbp/p300-interacting trans (219 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 916.6 bits: 176.5 E(85289): 2.6e-44 Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:27-219) 10 20 30 pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL :::::::::::::::::::::::::::::::::: NP_001 MEPSAQQLQLAASLPANLSNFCQGSEMPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 MQLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD 130 140 150 160 170 180 160 170 180 190 pF1KB8 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC ::::::::::::::::::::::::::::::::::::::: NP_001 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC 190 200 210 >>NP_001161860 (OMIM: 602937,614431,614433) cbp/p300-int (270 aa) initn: 344 init1: 248 opt: 258 Z-score: 201.3 bits: 44.5 E(85289): 0.00018 Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:89-259) 20 30 40 50 60 70 pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP :.. :... : :..:.:. . . NP_001 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK 60 70 80 90 100 110 80 90 100 110 pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE . :: :: :: :. :.. :.... ...::: :: NP_001 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG 120 130 140 150 160 170 120 130 140 150 160 pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD .: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::: NP_001 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD 180 190 200 210 220 230 170 180 190 pF1KB8 RANELPELWLGQNEFDFTADFPSSC : .:::::::::::::: .:: NP_001 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 240 250 260 270 >>NP_006070 (OMIM: 602937,614431,614433) cbp/p300-intera (270 aa) initn: 344 init1: 248 opt: 258 Z-score: 201.3 bits: 44.5 E(85289): 0.00018 Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:89-259) 20 30 40 50 60 70 pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP :.. :... : :..:.:. . . NP_006 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK 60 70 80 90 100 110 80 90 100 110 pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE . :: :: :: :. :.. :.... ...::: :: NP_006 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG 120 130 140 150 160 170 120 130 140 150 160 pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD .: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::: NP_006 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD 180 190 200 210 220 230 170 180 190 pF1KB8 RANELPELWLGQNEFDFTADFPSSC : .:::::::::::::: .:: NP_006 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 240 250 260 270 >>NP_001161861 (OMIM: 602937,614431,614433) cbp/p300-int (275 aa) initn: 344 init1: 248 opt: 258 Z-score: 201.2 bits: 44.5 E(85289): 0.00018 Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:94-264) 20 30 40 50 60 70 pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP :.. :... : :..:.:. . . NP_001 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK 70 80 90 100 110 120 80 90 100 110 pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE . :: :: :: :. :.. :.... ...::: :: NP_001 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG 130 140 150 160 170 180 120 130 140 150 160 pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD .: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::: NP_001 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD 190 200 210 220 230 240 170 180 190 pF1KB8 RANELPELWLGQNEFDFTADFPSSC : .:::::::::::::: .:: NP_001 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 250 260 270 >>NP_597724 (OMIM: 606815) cbp/p300-interacting transact (184 aa) initn: 230 init1: 147 opt: 254 Z-score: 201.0 bits: 43.9 E(85289): 0.00019 Smith-Waterman score: 254; 34.5% identity (55.0% similar) in 171 aa overlap (36-192:14-176) 10 20 30 40 50 60 pF1KB8 RPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSS :. ..: : : . . .: .:. NP_597 MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSG 10 20 30 40 70 80 90 100 110 pF1KB8 GSPIGSPTTTPPTK-----------PPS-FNLHPA--PHLLASMQLQKLNSQYQGMAAAT : :.: :: . ::: :. :: : . .:: . . : : ::: NP_597 LRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 PGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRAN :. :: :: : : . . . .: :.. . .:.. .:::.: :: .:::: :. NP_597 PNAPG--GPP-----GPQPAPSAA-APPPPAHALGGMDAELIDEEALTSLELELGLHRVR 110 120 130 140 150 180 190 pF1KB8 ELPELWLGQNEFDFTADFPSSC :::::.:::.::: .:. :. NP_597 ELPELFLGQSEFDCFSDLGSAPPAGSVSC 160 170 180 193 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:19:47 2016 done: Fri Nov 4 16:19:48 2016 Total Scan time: 6.300 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]