Result of FASTA (omim) for
pF1KB8894
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8894, 217 aa
1>>>pF1KB8894 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2468+/-0.000281; mu= 12.8178+/- 0.018
mean_var=137.4543+/-28.016, 0's: 0 Z-trim(122.9): 66 B-trim: 2122 in 1/55
Lambda= 0.109394
statistics sampled from 41628 (41698) to 41628 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.489), width: 16
Scan time: 6.390
The best scores are: opt bits E(85289)
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 1471 242.2 4.9e-64
XP_005268588 (OMIM: 602406) PREDICTED: heart- and ( 214) 691 119.1 5.5e-27
NP_004812 (OMIM: 602406) heart- and neural crest d ( 215) 689 118.8 6.9e-27
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 254 50.1 3e-06
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 253 50.0 3.4e-06
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 253 50.0 3.4e-06
NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 218 44.4 0.00016
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 217 44.3 0.00018
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 217 44.3 0.00018
NP_004307 (OMIM: 100790,209880) achaete-scute homo ( 236) 213 43.7 0.0003
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189) 211 43.3 0.00032
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 205 42.3 0.00056
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 205 42.3 0.00056
NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179) 205 42.3 0.0006
NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179) 205 42.3 0.0006
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172) 203 42.0 0.00073
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172) 203 42.0 0.00073
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331) 203 42.3 0.0011
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331) 203 42.3 0.0011
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 203 42.3 0.0011
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331) 203 42.3 0.0011
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331) 203 42.3 0.0011
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 203 42.3 0.0011
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 203 42.3 0.0011
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331) 203 42.3 0.0011
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 203 42.3 0.0011
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 203 42.3 0.0011
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 203 42.3 0.0011
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206) 197 41.1 0.0016
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280) 197 41.3 0.002
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302) 197 41.3 0.0021
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351) 197 41.4 0.0023
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108) 186 39.1 0.0034
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 190 40.2 0.0047
NP_660161 (OMIM: 609875) protein atonal homolog 7 ( 152) 183 38.8 0.006
>>NP_068808 (OMIM: 602407) heart- and neural crest deriv (217 aa)
initn: 1471 init1: 1471 opt: 1471 Z-score: 1270.7 bits: 242.2 E(85289): 4.9e-64
Smith-Waterman score: 1471; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB8 MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEK
130 140 150 160 170 180
190 200 210
pF1KB8 RKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
:::::::::::::::::::::::::::::::::::::
NP_068 RKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
190 200 210
>>XP_005268588 (OMIM: 602406) PREDICTED: heart- and neur (214 aa)
initn: 658 init1: 386 opt: 691 Z-score: 605.4 bits: 119.1 E(85289): 5.5e-27
Smith-Waterman score: 691; 54.4% identity (73.9% similar) in 226 aa overlap (1-217:1-214)
10 20 30 40 50
pF1KB8 MSLVGGFPHHPVVHHEGYPFAAAAAAAAA---AAASRCSHEENPYFHGWLIGHPEMSPPD
:.:::.. :: ::. .: : . :::: :.: :::..::.. : . ::
XP_005 MNLVGSYAHH---HHHHHPHPAHPMLHEPFLFGPASRC-HQERPYFQSWLLS-PADAAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 YSMALSYSPEYASGAAGLDHSHYG-GVPPGAGP---PGLGGPRPVKRRGTANRKERRRTQ
. . .: :..::. . :: . :: .: .::: : .:.:.. .::::::.
XP_005 FPAG---GPPPAAAAAA---TAYGPDARPGQSPGRLEALGG-RLGRRKGSGPKKERRRTE
60 70 80 90 100
120 130 140 150 160 170
pF1KB8 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKK
::::::::::::::::::::::::::::::::::::::::.:::: :.:. ::::::.::
XP_005 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKK
110 120 130 140 150 160
180 190 200 210
pF1KB8 TDV-KEEKRKKEL-NEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
.: .: :::.:: .: . ... .:. ::::::::.::::::.:
XP_005 ADGGRESKRKRELQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ
170 180 190 200 210
>>NP_004812 (OMIM: 602406) heart- and neural crest deriv (215 aa)
initn: 678 init1: 386 opt: 689 Z-score: 603.7 bits: 118.8 E(85289): 6.9e-27
Smith-Waterman score: 689; 54.2% identity (73.6% similar) in 227 aa overlap (1-217:1-215)
10 20 30 40 50
pF1KB8 MSLVGGFPHHPVVHHEGYPFAAAAAAAAA---AAASRCSHEENPYFHGWLIGHPEMSPPD
:.:::.. :: ::. .: : . :::: :.: :::..::.. : . ::
NP_004 MNLVGSYAHH---HHHHHPHPAHPMLHEPFLFGPASRC-HQERPYFQSWLLS-PADAAPD
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 YSMALSYSPEYASGAAGLDHSHYG-GVPPGAGP---PGLGGPRPVKRRGTANRKERRRTQ
. . .: :..::. . :: . :: .: .::: : .:.:.. .::::::.
NP_004 FPAG---GPPPAAAAAA---TAYGPDARPGQSPGRLEALGG-RLGRRKGSGPKKERRRTE
60 70 80 90 100
120 130 140 150 160 170
pF1KB8 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKK
::::::::::::::::::::::::::::::::::::::::.:::: :.:. ::::::.::
NP_004 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKK
110 120 130 140 150 160
180 190 200 210
pF1KB8 TDV-KEEKRKKEL--NEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
.: .: :::.:: .: . ... .:. ::::::::.::::::.:
NP_004 ADGGRESKRKRELQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ
170 180 190 200 210
>>NP_004600 (OMIM: 601010) transcription factor 15 [Homo (199 aa)
initn: 252 init1: 236 opt: 254 Z-score: 233.1 bits: 50.1 E(85289): 3e-06
Smith-Waterman score: 254; 42.0% identity (65.5% similar) in 119 aa overlap (52-169:30-143)
30 40 50 60 70 80
pF1KB8 AAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYG
: . : :.. .:: : . : .. .
NP_004 MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGPEAARRGPGPGGGRRA
10 20 30 40 50
90 100 110 120 130 140
pF1KB8 GVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTL
: :::: . :..: .:: .:: ::::.:.::. :: ::. :.: :::::.::
NP_004 GGGGGAGPVVV-----VRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB8 RLATSYIAYLMDLLAKDDQNGEAEA-FKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKT
:::.::::.: ..: :. ... :.:
NP_004 RLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQPRSICTFCLSNQRK
120 130 140 150 160 170
>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra (201 aa)
initn: 285 init1: 244 opt: 253 Z-score: 232.2 bits: 50.0 E(85289): 3.4e-06
Smith-Waterman score: 254; 42.5% identity (63.8% similar) in 127 aa overlap (50-165:16-141)
20 30 40 50 60 70
pF1KB8 FAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSP----PDYSMALSYSPEYA----SG
.::.:: : . : : : ..
NP_001 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAA
10 20 30 40
80 90 100 110 120
pF1KB8 AAGLDHSHY--GGVPPGAGPPGLGGP-RPVKRRGTANRKERRRTQSINSAFAELRECIPN
::. .. :: :.: :: : : : ..: ::: .:: ::.:.:.::. :: ::.
NP_001 RCGLQGARRRAGGRRAGGGGPG-GRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 VPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEI
::: :::::.:::::.:::..: ..: . :...
NP_001 EPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPP
110 120 130 140 150 160
190 200 210
pF1KB8 LKSTVSSNDKKTKGRTGWPQHVWALELKQ
NP_001 PPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
170 180 190 200
>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo (201 aa)
initn: 285 init1: 244 opt: 253 Z-score: 232.2 bits: 50.0 E(85289): 3.4e-06
Smith-Waterman score: 254; 42.5% identity (63.8% similar) in 127 aa overlap (50-165:16-141)
20 30 40 50 60 70
pF1KB8 FAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSP----PDYSMALSYSPEYA----SG
.::.:: : . : : : ..
XP_006 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAA
10 20 30 40
80 90 100 110 120
pF1KB8 AAGLDHSHY--GGVPPGAGPPGLGGP-RPVKRRGTANRKERRRTQSINSAFAELRECIPN
::. .. :: :.: :: : : : ..: ::: .:: ::.:.:.::. :: ::.
XP_006 RCGLQGARRRAGGRRAGGGGPG-GRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 VPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEI
::: :::::.:::::.:::..: ..: . :...
XP_006 EPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPP
110 120 130 140 150 160
190 200 210
pF1KB8 LKSTVSSNDKKTKGRTGWPQHVWALELKQ
XP_006 PPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
170 180 190 200
>>NP_005089 (OMIM: 603628) musculin [Homo sapiens] (206 aa)
initn: 241 init1: 193 opt: 218 Z-score: 202.2 bits: 44.4 E(85289): 0.00016
Smith-Waterman score: 218; 32.5% identity (58.6% similar) in 169 aa overlap (1-162:12-171)
10 20 30 40
pF1KB8 MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIG
: : : ..:: . :. .. . :. . . ..::.: :
NP_005 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPD------G
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 HPE---MSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGP-PGLGGPRPVKR--RGT
. : .. . . . . ..:..: : :: : : :. :. :. :..
NP_005 EEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGG---GKKPLPAKGSAAECKQSQRNA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 ANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD-QNG
:: .:: : . ...::..:. .: :: ::::::. :::::.::::.: .:: .: .::
NP_005 ANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENG
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 EAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
NP_005 YVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
180 190 200
>>XP_011513798 (OMIM: 101400,123100,180750,601622) PREDI (202 aa)
initn: 297 init1: 124 opt: 217 Z-score: 201.5 bits: 44.3 E(85289): 0.00018
Smith-Waterman score: 217; 45.5% identity (73.9% similar) in 88 aa overlap (81-163:85-171)
60 70 80 90 100
pF1KB8 PEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGG-PRPVK----RRGTAN
::. :.: . :: :. . .: ::
XP_011 AAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMAN
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 RKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAE
.::.::::.: ::: ::. ::..:.: :::::.::.::. :: .:...: .:. ...
XP_011 VRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKMA
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 AFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
XP_011 SCSYVAHERLSYAFSVWRMEGAWSMSASH
180 190 200
>>NP_000465 (OMIM: 101400,123100,180750,601622) twist-re (202 aa)
initn: 297 init1: 124 opt: 217 Z-score: 201.5 bits: 44.3 E(85289): 0.00018
Smith-Waterman score: 217; 45.5% identity (73.9% similar) in 88 aa overlap (81-163:85-171)
60 70 80 90 100
pF1KB8 PEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGG-PRPVK----RRGTAN
::. :.: . :: :. . .: ::
NP_000 AAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMAN
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 RKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAE
.::.::::.: ::: ::. ::..:.: :::::.::.::. :: .:...: .:. ...
NP_000 VRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKMA
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 AFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
NP_000 SCSYVAHERLSYAFSVWRMEGAWSMSASH
180 190 200
>>NP_004307 (OMIM: 100790,209880) achaete-scute homolog (236 aa)
initn: 349 init1: 158 opt: 213 Z-score: 197.2 bits: 43.7 E(85289): 0.0003
Smith-Waterman score: 246; 31.9% identity (56.4% similar) in 204 aa overlap (8-195:20-211)
10 20 30
pF1KB8 MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAAS-----------RCSH
:..: . . ::.::::::::::. . ..
NP_004 MESSAKMESGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 EENPYFHGWLIGHP-----EMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGL
.. : .. :.: . .: . . : ::: :. : .: : : .
NP_004 QQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAA-
70 80 90 100 110
100 110 120 130 140 150
pF1KB8 GGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLM
: :: :..:: :.. .: .:: ::: .:: :. :.::..::: :. :: :.
NP_004 -----VARR---NERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 DLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWA
.:: :.... . ::.: . . .. . ...:: . : :::
NP_004 QLL--DEHDAVSAAFQAGVLSPTISPN-YSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQE
180 190 200 210 220
pF1KB8 LELKQ
NP_004 LLDFTNWF
230
217 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:23:01 2016 done: Fri Nov 4 16:23:02 2016
Total Scan time: 6.390 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]