FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8899, 233 aa 1>>>pF1KB8899 233 - 233 aa - 233 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0891+/-0.000314; mu= 11.5251+/- 0.020 mean_var=106.6396+/-21.997, 0's: 0 Z-trim(119.3): 262 B-trim: 1787 in 2/54 Lambda= 0.124198 statistics sampled from 32764 (33075) to 32764 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.388), width: 16 Scan time: 7.030 The best scores are: opt bits E(85289) NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 1616 299.5 3.3e-81 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 589 115.4 7.9e-26 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 589 115.4 7.9e-26 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 589 115.4 7.9e-26 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 589 115.5 9.6e-26 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 513 101.7 7.5e-22 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 513 101.8 1e-21 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 462 92.7 6.5e-19 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 455 91.4 1.3e-18 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 445 89.7 5.1e-18 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 435 87.9 1.8e-17 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 428 86.6 3.9e-17 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 422 85.6 9.1e-17 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 422 85.6 9.1e-17 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 421 85.4 9.9e-17 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 418 84.9 1.7e-16 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 413 83.9 2.4e-16 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 408 83.0 4.9e-16 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 388 79.5 6.7e-15 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 381 78.2 1.4e-14 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 381 78.2 1.4e-14 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 380 78.1 1.8e-14 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 370 76.2 5.4e-14 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 358 73.8 1.3e-13 NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 338 70.6 3.8e-12 NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 309 65.3 1.1e-10 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 306 64.9 2.2e-10 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 304 64.6 3.1e-10 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 304 64.6 3.1e-10 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 304 64.6 3.1e-10 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 304 64.6 3.1e-10 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 304 64.6 3.1e-10 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 304 64.6 3.1e-10 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 304 64.6 3.1e-10 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 301 63.9 3.1e-10 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 294 62.6 7e-10 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 295 62.9 7.1e-10 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 295 62.9 8.1e-10 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 295 62.9 8.1e-10 NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 294 62.7 8.9e-10 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 295 63.0 9.3e-10 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 295 63.0 9.4e-10 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 295 63.0 9.4e-10 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 295 63.0 9.4e-10 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 295 63.0 9.4e-10 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 295 63.0 9.4e-10 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 295 63.0 9.4e-10 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 295 63.0 1e-09 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 291 62.1 1.1e-09 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 295 63.1 1.2e-09 >>NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [Homo (233 aa) initn: 1616 init1: 1616 opt: 1616 Z-score: 1579.0 bits: 299.5 E(85289): 3.3e-81 Smith-Waterman score: 1616; 100.0% identity (100.0% similar) in 233 aa overlap (1-233:1-233) 10 20 30 40 50 60 pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 190 200 210 220 230 >>XP_005257340 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 780 init1: 551 opt: 589 Z-score: 584.7 bits: 115.4 E(85289): 7.9e-26 Smith-Waterman score: 815; 57.2% identity (75.8% similar) in 236 aa overlap (1-233:1-224) 10 20 30 40 50 pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGY-DALRPFPASYGASSLPDKTYTSPCFYQ ::::::: ::: .: :::.:::::::::..:: : :: .:: :: . :: ... .: XP_005 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 QSNSVLACNRASY-EYG-ASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS ... . .::. .:: : :: .:. :. . ::. .: : : :: . : : . XP_005 PAGG--GYGRAAPCDYGPAPAFYREKE-SACALSGADEQ--PP----FHPEPR-KSDCA- 70 80 90 100 120 130 140 150 160 170 pF1KB8 GQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFN : :.. : ..: ..:::::::::::: .. .: :::::::::::::::::::::.: XP_005 -QDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 RYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE ::::::::::::.:::::::::::::::::::::::.::....: :.:. : : .: XP_005 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 >>NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [Homo (224 aa) initn: 780 init1: 551 opt: 589 Z-score: 584.7 bits: 115.4 E(85289): 7.9e-26 Smith-Waterman score: 815; 57.2% identity (75.8% similar) in 236 aa overlap (1-233:1-224) 10 20 30 40 50 pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGY-DALRPFPASYGASSLPDKTYTSPCFYQ ::::::: ::: .: :::.:::::::::..:: : :: .:: :: . :: ... .: NP_061 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 QSNSVLACNRASY-EYG-ASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS ... . .::. .:: : :: .:. :. . ::. .: : : :: . : : . NP_061 PAGG--GYGRAAPCDYGPAPAFYREKE-SACALSGADEQ--PP----FHPEPR-KSDCA- 70 80 90 100 120 130 140 150 160 170 pF1KB8 GQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFN : :.. : ..: ..:::::::::::: .. .: :::::::::::::::::::::.: NP_061 -QDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 RYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE ::::::::::::.:::::::::::::::::::::::.::....: :.:. : : .: NP_061 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 >>XP_005257341 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 780 init1: 551 opt: 589 Z-score: 584.7 bits: 115.4 E(85289): 7.9e-26 Smith-Waterman score: 815; 57.2% identity (75.8% similar) in 236 aa overlap (1-233:1-224) 10 20 30 40 50 pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGY-DALRPFPASYGASSLPDKTYTSPCFYQ ::::::: ::: .: :::.:::::::::..:: : :: .:: :: . :: ... .: XP_005 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 QSNSVLACNRASY-EYG-ASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS ... . .::. .:: : :: .:. :. . ::. .: : : :: . : : . XP_005 PAGG--GYGRAAPCDYGPAPAFYREKE-SACALSGADEQ--PP----FHPEPR-KSDCA- 70 80 90 100 120 130 140 150 160 170 pF1KB8 GQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFN : :.. : ..: ..:::::::::::: .. .: :::::::::::::::::::::.: XP_005 -QDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 RYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE ::::::::::::.:::::::::::::::::::::::.::....: :.:. : : .: XP_005 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 >>XP_011523029 (OMIM: 142961) PREDICTED: homeobox protei (288 aa) initn: 764 init1: 551 opt: 589 Z-score: 583.2 bits: 115.5 E(85289): 9.6e-26 Smith-Waterman score: 815; 57.2% identity (75.8% similar) in 236 aa overlap (1-233:65-288) 10 20 30 pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQA ::::::: ::: .: :::.:::::::::.. XP_011 GFNAARRSDYKTQQIINPAEQQRPRAPPLPMSSYFVNSTFPVTLASGQESFLGQLPLYSS 40 50 60 70 80 90 40 50 60 70 80 pF1KB8 GY-DALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASY-EYG-ASCFYSDKDLSG :: : :: .:: :: . :: ... .: ... . .::. .:: : :: .:. :. XP_011 GYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGG--GYGRAAPCDYGPAPAFYREKE-SA 100 110 120 130 140 150 90 100 110 120 130 140 pF1KB8 ASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCA . ::. .: : : :: . : : . : :.. : ..: ..:::::::::::: XP_011 CALSGADEQ--PP----FHPEPR-KSDCA--QDKSVFGETEEQKCSTPVYPWMQRMNSCN 160 170 180 190 200 150 160 170 180 190 200 pF1KB8 GAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRR .. .: :::::::::::::::::::::.:::::::::::::.::::::::::::::::: XP_011 SSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRR 210 220 230 240 250 260 210 220 230 pF1KB8 MKWKKENKLINSTQPSGEDSEAKAGE ::::::.::....: :.:. : : .: XP_011 MKWKKESKLLSASQLSAEEEEEKQAE 270 280 >>NP_710160 (OMIM: 142972) homeobox protein Hox-C6 isofo (153 aa) initn: 521 init1: 488 opt: 513 Z-score: 513.3 bits: 101.7 E(85289): 7.5e-22 Smith-Waterman score: 513; 67.2% identity (81.0% similar) in 116 aa overlap (114-229:21-133) 90 100 110 120 130 140 pF1KB8 DLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRM : :: ::.. :.: . .::::::: NP_710 MLSNCRQNTLGHNTQTSIAQDFSSEQGRT---APQDQKASIQIYPWMQRM 10 20 30 40 150 160 170 180 190 200 pF1KB8 NSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF :: .:. ::. ::::: :.:::::::::::::::::::::::::::::::::::::::: NP_710 NSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF 50 60 70 80 90 100 210 220 230 pF1KB8 QNRRMKWKKENKLINSTQPSGEDSEAKAGE ::::::::::..: .. . .: . : NP_710 QNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE 110 120 130 140 150 >>NP_004494 (OMIM: 142972) homeobox protein Hox-C6 isofo (235 aa) initn: 714 init1: 488 opt: 513 Z-score: 510.8 bits: 101.8 E(85289): 1e-21 Smith-Waterman score: 696; 49.8% identity (71.6% similar) in 229 aa overlap (1-229:1-215) 10 20 30 40 50 60 pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ :.:::.::.. : .::: : .. : ...:: .: : ..:::. .. :..: . : NP_004 MNSYFTNPSLSCHLAGGQD-VLPNVALNSTAYDPVRHF-STYGAAVAQNRIYSTPFYSPQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG : :.. .:. :.::.. ::..::. . . .: : . : : : :: :: NP_004 ENVVFSSSRGPYDYGSNSFYQEKDMLS-----NCRQNTLGHNTQTSIAQ----DFSSEQG 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL .. . :.: . .::::::::: .:. ::. ::::: :.::::::::::::::::: NP_004 RTAPQ---DQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYL 110 120 130 140 150 160 190 200 210 220 230 pF1KB8 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE :::::::::::::::::::::::::::::::::..: .. . .: . : NP_004 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKRE 170 180 190 200 210 220 NP_004 ETEEEKQKE 230 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 492 init1: 444 opt: 462 Z-score: 460.6 bits: 92.7 E(85289): 6.5e-19 Smith-Waterman score: 462; 45.3% identity (66.1% similar) in 192 aa overlap (36-216:71-256) 10 20 30 40 50 60 pF1KB8 VNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLP-DKTYTSPCFYQQSNSV : . :: ::. : . :..: .: . NP_061 HSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAS--ASAAPAEPRYSQPATSTHSPQP 50 60 70 80 90 70 80 90 100 110 pF1KB8 --LACNRASYEYGASCFYSDKDL----SGASP-SGS---GKQRGPGDYLHFSPEQQYKPD : :. .. :.. .. :. :::: .:: ....: : : .. : NP_061 DPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTA---SGAEEDAP- 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB8 SSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEF .:: :..: . . .::::.... . : .:.:.: .::::::::::::: NP_061 ASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEF 160 170 180 190 200 210 180 190 200 210 220 230 pF1KB8 HFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE :::::::::::::::.::::.:::::::::::::::::.::: NP_061 HFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 220 230 240 250 260 270 >>NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [Homo (217 aa) initn: 439 init1: 392 opt: 455 Z-score: 455.1 bits: 91.4 E(85289): 1.3e-18 Smith-Waterman score: 456; 43.3% identity (62.3% similar) in 215 aa overlap (40-233:12-215) 10 20 30 40 50 60 pF1KB8 FPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNR ..: ::: ..... : .:.. ..: : NP_004 MSSLYYANTLFSKYPASS---SVFATGAFPEQTSCAFASNP 10 20 30 70 80 90 100 110 pF1KB8 ASYEYGASCFYS-DKDLSGASPSGSGK--QRGPGDY------------LHFSP-EQQYK- :::. : ...: :.:.: : . : : .: .: ::. . NP_004 QRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSG 40 50 60 70 80 90 120 130 140 150 160 pF1KB8 --P-DSSSGQG-KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTL : ::... : : .: . . .::::. :. .:::::::::::: NP_004 VCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSS--------GTDRKRGRQTYTRYQTL 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB8 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE :::::::.:::::::::::::..:::::::::::::::::::::::: . . . .: NP_004 ELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAE 160 170 180 190 200 210 230 pF1KB8 AKAGE :. : NP_004 AEEEEEE >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 449 init1: 366 opt: 445 Z-score: 444.5 bits: 89.7 E(85289): 5.1e-18 Smith-Waterman score: 447; 39.1% identity (54.8% similar) in 248 aa overlap (1-231:3-230) 10 20 30 40 50 pF1KB8 MSSYFVN-----PTFPGSLPSGQDSFLG-QLPLYQAGYDALRPFPASYGASSLPDKTY ::::.:: : :: : ..:: : : .: .. ::. : : NP_055 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGG--------GAQGADFQPPGLY 10 20 30 40 50 60 70 80 90 100 pF1KB8 TSPCFYQQSNSVLACNRASYEYGASCFYSDKDLS----GASPSGSGKQRG-PGDYLHFSP : : .: .:.: . : : :.: : . . ::. : NP_055 PRPDFGEQP------------FGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPP 60 70 80 90 100 110 120 130 140 150 160 pF1KB8 EQQYKP----DSSSGQGKALHDEGADRKYTSPVYPWMQRM--NSCAGAVYGSHGRRGRQT : . : . :. : . :::::... :: :.. .:.: . NP_055 APPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTA 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 YTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQ ::: :.::::::::::::::::::::::..:::.:::::::::::::::::..:: :. NP_055 YTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKG 170 180 190 200 210 220 230 pF1KB8 PSGEDSEAKAGE :. .: ... NP_055 RSSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL 230 240 250 233 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:00:07 2016 done: Sat Nov 5 20:00:08 2016 Total Scan time: 7.030 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]