FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8901, 233 aa 1>>>pF1KB8901 233 - 233 aa - 233 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4893+/-0.00085; mu= 13.2360+/- 0.051 mean_var=68.1229+/-13.493, 0's: 0 Z-trim(106.8): 26 B-trim: 0 in 0/50 Lambda= 0.155392 statistics sampled from 9154 (9175) to 9154 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.282), width: 16 Scan time: 2.050 The best scores are: opt bits E(32554) CCDS13189.1 BCL2L1 gene_id:598|Hs108|chr20 ( 233) 1550 356.2 1.1e-98 CCDS13188.1 BCL2L1 gene_id:598|Hs108|chr20 ( 170) 816 191.6 2.8e-49 CCDS11981.1 BCL2 gene_id:596|Hs108|chr18 ( 239) 599 143.0 1.6e-34 CCDS45882.1 BCL2 gene_id:596|Hs108|chr18 ( 205) 551 132.2 2.5e-31 CCDS9591.1 BCL2L2 gene_id:599|Hs108|chr14 ( 193) 531 127.7 5.2e-30 CCDS55906.1 PABPN1 gene_id:100529063|Hs108|chr14 ( 333) 462 112.4 3.8e-25 >>CCDS13189.1 BCL2L1 gene_id:598|Hs108|chr20 (233 aa) initn: 1550 init1: 1550 opt: 1550 Z-score: 1885.5 bits: 356.2 E(32554): 1.1e-98 Smith-Waterman score: 1550; 100.0% identity (100.0% similar) in 233 aa overlap (1-233:1-233) 10 20 30 40 50 60 pF1KB8 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 WIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 190 200 210 220 230 >>CCDS13188.1 BCL2L1 gene_id:598|Hs108|chr20 (170 aa) initn: 1093 init1: 816 opt: 816 Z-score: 998.3 bits: 191.6 E(32554): 2.8e-49 Smith-Waterman score: 971; 73.0% identity (73.0% similar) in 233 aa overlap (1-233:1-170) 10 20 30 40 50 60 pF1KB8 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP ::::: CCDS13 QSFEQ------------------------------------------------------- 190 200 210 220 230 pF1KB8 WIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK ::::::::::::::::::::::::::::::::::::::::::::: CCDS13 --------DTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 130 140 150 160 170 >>CCDS11981.1 BCL2 gene_id:596|Hs108|chr18 (239 aa) initn: 606 init1: 524 opt: 599 Z-score: 733.2 bits: 143.0 E(32554): 1.6e-34 Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (5-196:11-203) 10 20 30 40 pF1KB8 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS :::.:. .. :::::.:: :. .:: . . :: : : . .:: CCDS11 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS : . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :. CCDS11 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI ...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. : CCDS11 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL : ::. ::: ::. :::.:::::.:::::: CCDS11 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG 180 190 200 210 220 230 >>CCDS45882.1 BCL2 gene_id:596|Hs108|chr18 (205 aa) initn: 558 init1: 476 opt: 551 Z-score: 676.0 bits: 132.2 E(32554): 2.5e-31 Smith-Waterman score: 551; 49.5% identity (70.8% similar) in 192 aa overlap (5-188:11-195) 10 20 30 40 pF1KB8 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS :::.:. .. :::::.:: :. .:: . . :: : : . .:: CCDS45 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS : . .: . . ..::. :: .. : .: .:. .::.:::.: :::: :. CCDS45 PAASRDPVARTSPLQTPAAPGA----AAGPALSPVP-PVVHLTLRQAGDDFSRRYRRDFA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI ...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. : CCDS45 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL : ::. ::: ::. :::.:::: CCDS45 ALWMTEYLNRHLHTWIQDNGGWVGALGDVSLG 180 190 200 >>CCDS9591.1 BCL2L2 gene_id:599|Hs108|chr14 (193 aa) initn: 595 init1: 507 opt: 531 Z-score: 652.2 bits: 127.7 E(32554): 5.2e-30 Smith-Waterman score: 531; 51.7% identity (77.5% similar) in 151 aa overlap (82-231:37-185) 60 70 80 90 100 110 pF1KB8 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS : : ..::.: :::::: :.::.::::.. CCDS95 APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA 10 20 30 40 50 60 120 130 140 150 160 170 pF1KB8 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM :::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... :: CCDS95 QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM 70 80 90 100 110 120 180 190 200 210 220 230 pF1KB8 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF ..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.: CCDS95 VAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV 130 140 150 160 170 180 pF1KB8 SRK . CCDS95 TVGAFFASK 190 >>CCDS55906.1 PABPN1 gene_id:100529063|Hs108|chr14 (333 aa) initn: 526 init1: 460 opt: 462 Z-score: 565.0 bits: 112.4 E(32554): 3.8e-25 Smith-Waterman score: 462; 58.7% identity (82.6% similar) in 109 aa overlap (82-189:37-145) 60 70 80 90 100 110 pF1KB8 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS : : ..::.: :::::: :.::.::::.. CCDS55 APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA 10 20 30 40 50 60 120 130 140 150 160 170 pF1KB8 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM :::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... :: CCDS55 QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM 70 80 90 100 110 120 180 190 200 210 220 230 pF1KB8 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF ..::. .: ::. .:::. CCDS55 VAYLETQLADWIHSSGGWELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPPGNAGPV 130 140 150 160 170 180 233 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:25:07 2016 done: Fri Nov 4 16:25:07 2016 Total Scan time: 2.050 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]