FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8902, 234 aa 1>>>pF1KB8902 234 - 234 aa - 234 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8088+/-0.000316; mu= 5.4160+/- 0.020 mean_var=201.0421+/-40.004, 0's: 0 Z-trim(123.0): 237 B-trim: 0 in 0/60 Lambda= 0.090455 statistics sampled from 41748 (42018) to 41748 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.493), width: 16 Scan time: 7.900 The best scores are: opt bits E(85289) NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 1574 216.7 2.7e-56 NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 1002 141.9 6e-34 NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 367 59.4 8.9e-09 NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 316 52.7 8.4e-07 NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 303 51.1 3.1e-06 NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 294 49.7 5.2e-06 NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 282 48.2 1.7e-05 XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 282 48.2 1.7e-05 NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 281 48.2 2.4e-05 NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 280 48.0 2.4e-05 NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 278 47.7 2.7e-05 NP_003308 (OMIM: 118700,188550,600635,610978) home ( 371) 278 47.8 3e-05 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 279 48.0 3.1e-05 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 279 48.0 3.1e-05 NP_001073136 (OMIM: 118700,188550,600635,610978) h ( 401) 278 47.8 3.2e-05 NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 ( 354) 275 47.4 3.8e-05 NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 272 46.9 4.1e-05 NP_006553 (OMIM: 604255) transcription factor LBX1 ( 281) 272 46.9 4.3e-05 NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 263 45.7 9.7e-05 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 266 46.3 0.0001 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 266 46.3 0.0001 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 266 46.3 0.0001 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 266 46.3 0.0001 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 266 46.3 0.0001 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 266 46.3 0.0001 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 266 46.3 0.0001 NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 264 46.0 0.0001 NP_612138 (OMIM: 601911,616788) homeobox protein D ( 240) 259 45.1 0.00012 NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 259 45.2 0.00013 NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 257 45.0 0.00017 XP_006723629 (OMIM: 604612) PREDICTED: homeobox pr ( 202) 251 44.0 0.00023 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 253 44.4 0.00023 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 253 44.4 0.00023 NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 253 44.4 0.00024 NP_001476 (OMIM: 601135) homeobox protein GBX-2 is ( 348) 254 44.6 0.00025 NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 253 44.5 0.00027 XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 253 44.5 0.00027 NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 ( 273) 251 44.1 0.00028 NP_001980 (OMIM: 142996) homeobox even-skipped hom ( 407) 251 44.3 0.00037 NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 249 44.0 0.00041 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 247 43.7 0.00048 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 244 43.4 0.00069 NP_001925 (OMIM: 601911,616788) homeobox protein D ( 168) 235 41.9 0.00084 XP_016879780 (OMIM: 601911,616788) PREDICTED: home ( 168) 235 41.9 0.00084 >>NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 isof (234 aa) initn: 1574 init1: 1574 opt: 1574 Z-score: 1131.8 bits: 216.7 E(85289): 2.7e-56 Smith-Waterman score: 1574; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234) 10 20 30 40 50 60 pF1KB8 MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 RKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW 190 200 210 220 230 >>NP_001243268 (OMIM: 602041) homeobox protein Nkx-3.1 i (159 aa) initn: 1002 init1: 1002 opt: 1002 Z-score: 730.5 bits: 141.9 E(85289): 6e-34 Smith-Waterman score: 1002; 97.4% identity (98.1% similar) in 155 aa overlap (80-234:5-159) 50 60 70 80 90 100 pF1KB8 RQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENT :. : :::::::::::::::::::::::: NP_001 MLRVPEPRPGEAETLAETEPERHLGSYLLDSENT 10 20 30 110 120 130 140 150 160 pF1KB8 SGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 IWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSW 100 110 120 130 140 150 230 pF1KB8 SPAFW ::::: NP_001 SPAFW >>NP_001180 (OMIM: 602183,613330) homeobox protein Nkx-3 (333 aa) initn: 480 init1: 355 opt: 367 Z-score: 278.5 bits: 59.4 E(85289): 8.9e-09 Smith-Waterman score: 396; 39.6% identity (62.3% similar) in 212 aa overlap (32-230:136-322) 10 20 30 40 50 60 pF1KB8 LRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPE .:. ...: :. .. :.. . : :. : . NP_001 RCADARGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDD 110 120 130 140 150 160 70 80 90 100 110 120 pF1KB8 PEGGRSRAGAQNDQLSTGPRAAPEEAET-LAETEPERHLGSYLLDSENTSGALPRLPQTP : : ::. . : .: .. . . .:: : : : .: NP_001 GVGPR---GAHVSALCSGAGGGGGSGPAGVAEEEEE--------------------PAAP 170 180 190 200 130 140 150 160 170 180 pF1KB8 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK : .:::::::::.::.::::.:.::.:::.:::: :: .:::::::::::::::::::: NP_001 KPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTK 210 220 230 240 250 260 190 200 210 220 pF1KB8 RKQLSSEL---GDLEKHSSLPALKE---------EAFSRASLVSVYNSYPYYPYLYCVGS :.:....: . :. .. .: . :.. ::. . :: :::: ::. . NP_001 RRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSY-YYPY-YCLPG 270 280 290 300 310 320 230 pF1KB8 WSPAFW :. NP_001 WALSTCAAAAGTQ 330 >>NP_001129743 (OMIM: 217095,611770) homeobox protein Nk (301 aa) initn: 306 init1: 257 opt: 316 Z-score: 243.1 bits: 52.7 E(85289): 8.4e-07 Smith-Waterman score: 316; 38.7% identity (62.8% similar) in 191 aa overlap (17-198:27-205) 10 20 30 40 pF1KB8 MLRVPEPRPGEAKAEGAAPPTP---SKPLT-SFLIQDILRDGAQ-RQGGR :: : : ..: . ..: .: :.. ...: NP_001 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGG 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 TSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTG-PRAAPEEAETLA--ETEPERHLGSY ...:. : :: :: .: . : : :. . . : :. ::: .:. NP_001 GGGDRKLDGS-----EPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGN- 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 LLDSENTSGALPRLPQTPKQPQKRS-RAAFSHTQVIELERKFSHQKYLSAPERAHLAKNL ..... :. : : :: :.:. :. ::..::. :::.:..:.::::::: :::. : NP_001 --SGDSVRGG--RSEQ-PKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASAL 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 KLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYP .:: ::::::::::::: ::.. .. : .: : : NP_001 QLTSTQVKIWFQNRRYKCKRQRQDKSL-ELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAP 170 180 190 200 210 220 230 pF1KB8 YLYCVGSWSPAFW NP_001 AFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQ 230 240 250 260 270 280 >>NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 [Hom (364 aa) initn: 268 init1: 268 opt: 303 Z-score: 232.9 bits: 51.1 E(85289): 3.1e-06 Smith-Waterman score: 303; 42.5% identity (62.7% similar) in 153 aa overlap (84-228:104-254) 60 70 80 90 100 110 pF1KB8 PEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGS-YLLDSENTSGA :.: : :. .: : : : .:.: NP_660 NSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGD 80 90 100 110 120 130 120 130 140 150 160 pF1KB8 LPRLPQTPKQPQKRSR----AAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQV . . ..:. ::: . ::..::.::::.:..:.::::::: :::..:::: ::: NP_660 C-KAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQV 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB8 KIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEA---FSRASLVSVYNSYPYYPYLYC :::::::::: ::.. .. : .: :. : .. : . : . : : : : NP_660 KIWFQNRRYKCKRQRQDKSL-ELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYS 200 210 220 230 240 250 230 pF1KB8 VGSWSPAFW ::. NP_660 VGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGGGGGTSAATT 260 270 280 290 300 310 >>NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 [Hom (239 aa) initn: 274 init1: 274 opt: 294 Z-score: 228.9 bits: 49.7 E(85289): 5.2e-06 Smith-Waterman score: 301; 40.8% identity (60.5% similar) in 152 aa overlap (51-199:27-161) 30 40 50 60 70 pF1KB8 TPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPE-PEPEPEGGRSRAGAQNDQLSTG .:.:::. :.:.: .: :. : NP_055 MATSGRLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDP------CAAWLDS-ERG 10 20 30 40 80 90 100 110 120 130 pF1KB8 PRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIEL : :. :: : :: . .: : : . . .:. :. ::..:..:: NP_055 HY--PSSDESSLETSPP--------DSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLEL 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 ERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQL--SSELGDLEKHSSL ::.: .:.::::::: .::. :.:: :::::::::.::: :: . ..: :: . : NP_055 ERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAEL 100 110 120 130 140 150 200 210 220 230 pF1KB8 PALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW : NP_055 HAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSA 160 170 180 190 200 210 >>NP_005510 (OMIM: 600647) homeobox protein HMX2 [Homo s (273 aa) initn: 269 init1: 205 opt: 282 Z-score: 219.7 bits: 48.2 E(85289): 1.7e-05 Smith-Waterman score: 282; 33.1% identity (55.6% similar) in 239 aa overlap (9-228:30-257) 10 20 30 pF1KB8 MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGA :.:: : .. :. .. :. .. :: NP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW 10 20 30 40 50 60 40 50 60 70 80 pF1KB8 Q--------RQGGRTSSQRQRDPEPEP---EPEPEGGRSRAGAQNDQLSTGPRAAPEEAE . ..: . .. ... : : : :. :: . .: : : .: ... NP_005 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGG-----LERTPFLSPSHSD 70 80 90 100 110 90 100 110 120 130 140 pF1KB8 TLAETEPERHLGSYLLDSENTSGALPRLPQTPKQP---QKRSRAAFSHTQVIELERKFSH . : :: : . : . .. :: . .: .:..:..::..:: .:: :. NP_005 F--KEEKERLLPA---GSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDM 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB8 QKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLE-KHSSLPALKEE- ..:::. ::: ::..:.::::::: :::::: : :: :::.:: . :.: .: NP_005 KRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKR-QLSAELEAANMAHASAQTLVSMP 180 190 200 210 220 210 220 230 pF1KB8 -AFSRASL--VSVYNSYPYYPYLYCVGSWSPAFW .: .:: : : : . :: :: NP_005 LVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY 230 240 250 260 270 >>XP_005269800 (OMIM: 600647) PREDICTED: homeobox protei (273 aa) initn: 269 init1: 205 opt: 282 Z-score: 219.7 bits: 48.2 E(85289): 1.7e-05 Smith-Waterman score: 282; 33.1% identity (55.6% similar) in 239 aa overlap (9-228:30-257) 10 20 30 pF1KB8 MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGA :.:: : .. :. .. :. .. :: XP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW 10 20 30 40 50 60 40 50 60 70 80 pF1KB8 Q--------RQGGRTSSQRQRDPEPEP---EPEPEGGRSRAGAQNDQLSTGPRAAPEEAE . ..: . .. ... : : : :. :: . .: : : .: ... XP_005 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGG-----LERTPFLSPSHSD 70 80 90 100 110 90 100 110 120 130 140 pF1KB8 TLAETEPERHLGSYLLDSENTSGALPRLPQTPKQP---QKRSRAAFSHTQVIELERKFSH . : :: : . : . .. :: . .: .:..:..::..:: .:: :. XP_005 F--KEEKERLLPA---GSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDM 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB8 QKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLE-KHSSLPALKEE- ..:::. ::: ::..:.::::::: :::::: : :: :::.:: . :.: .: XP_005 KRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKR-QLSAELEAANMAHASAQTLVSMP 180 190 200 210 220 210 220 230 pF1KB8 -AFSRASL--VSVYNSYPYYPYLYCVGSWSPAFW .: .:: : : : . :: :: XP_005 LVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY 230 240 250 260 270 >>NP_064447 (OMIM: 605212) barH-like 2 homeobox protein (387 aa) initn: 251 init1: 194 opt: 281 Z-score: 217.1 bits: 48.2 E(85289): 2.4e-05 Smith-Waterman score: 288; 32.7% identity (55.2% similar) in 223 aa overlap (6-223:119-321) 10 20 30 pF1KB8 MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDIL .: : . :.: .: .::::.::: NP_064 HHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDIL 90 100 110 120 130 140 40 50 60 70 80 90 pF1KB8 RDGAQRQGGRTSSQRQRDPEPEPEPEP----EGGRSRAGAQNDQLSTGPRAAPEEAETLA :. . : .:. :. : :. : . .... . : :.... NP_064 GDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKR---EDSQSDI 150 160 170 180 190 200 100 110 120 130 140 150 pF1KB8 ETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSA . . .. :. . : : : : :.:.: .:.::: :. .:::.: .:::::. NP_064 KCHGTKEEGDREITSSRES---P--PVRAKKPRK-ARTAFSDHQLNQLERSFERQKYLSV 210 220 230 240 250 160 170 180 190 200 210 pF1KB8 PERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLV .: :: :.::.:::: :.:::: : ::. . .: :: : :: . ..: NP_064 QDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ---TAVG-LE-------LLAEAGNYSALQ 260 270 280 290 300 220 230 pF1KB8 SVYNS-YPYYPYLYCVGSWSPAFW .. : : :.: : NP_064 RMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPG 310 320 330 340 350 360 >>NP_061815 (OMIM: 142992,612109) homeobox protein HMX1 (348 aa) initn: 274 init1: 210 opt: 280 Z-score: 216.9 bits: 48.0 E(85289): 2.4e-05 Smith-Waterman score: 280; 36.8% identity (56.8% similar) in 185 aa overlap (9-188:89-266) 10 20 30 pF1KB8 MLRVPEPRPGEAKAEGAAPPTPSKPLT---SFLIQDIL :: :: :. :.. . . NP_061 QARRRRLQRRRQLLAGTGPGGEARARALLGPGALGLGPRPPPGPGPPFALGCGGAARWYP 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB8 RDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEP : . :: . . .:: :: : ::.. :: . :: :. .:: :: : NP_061 RAHGGYGGGLSPDTSDRDS---PETGEEMGRAE-GAW--PRGPGPGAVQREAAELAARGP 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB8 E--RHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPE . .: : . ..: . .:..:..::..::..:: :. ..:::. : NP_061 AAGTEEASELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAE 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB8 RAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSV :: :: .:.:::::::::::::: : :: ::..:: NP_061 RAGLAASLQLTETQVKIWFQNRRNKWKR-QLAAELEAASLSPPGAQRLVRVPVLYHESPP 240 250 260 270 280 290 220 230 pF1KB8 YNSYPYYPYLYCVGSWSPAFW NP_061 AAAAAGPPATLPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV 300 310 320 330 340 234 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:21:36 2016 done: Fri Nov 4 20:21:37 2016 Total Scan time: 7.900 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]