FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8904, 237 aa 1>>>pF1KB8904 237 - 237 aa - 237 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2337+/-0.000708; mu= 7.5967+/- 0.043 mean_var=144.8985+/-29.649, 0's: 0 Z-trim(115.5): 45 B-trim: 586 in 2/52 Lambda= 0.106547 statistics sampled from 16054 (16100) to 16054 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.495), width: 16 Scan time: 2.780 The best scores are: opt bits E(32554) CCDS13278.1 TGIF2 gene_id:60436|Hs108|chr20 ( 237) 1581 253.4 9.6e-68 CCDS11833.1 TGIF1 gene_id:7050|Hs108|chr18 ( 272) 533 92.4 3.3e-19 CCDS11832.1 TGIF1 gene_id:7050|Hs108|chr18 ( 286) 533 92.4 3.4e-19 CCDS11835.1 TGIF1 gene_id:7050|Hs108|chr18 ( 252) 532 92.2 3.5e-19 CCDS11834.1 TGIF1 gene_id:7050|Hs108|chr18 ( 401) 533 92.5 4.5e-19 CCDS58772.1 C20orf24 gene_id:100527943|Hs108|chr20 ( 155) 418 74.5 4.5e-14 CCDS14459.1 TGIF2LX gene_id:90316|Hs108|chrX ( 241) 416 74.3 7.8e-14 CCDS14775.1 TGIF2LY gene_id:90655|Hs108|chrY ( 185) 369 67.0 9.6e-12 >>CCDS13278.1 TGIF2 gene_id:60436|Hs108|chr20 (237 aa) initn: 1581 init1: 1581 opt: 1581 Z-score: 1329.7 bits: 253.4 E(32554): 9.6e-68 Smith-Waterman score: 1581; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGSPTGGLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGSPTGGLF 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 NTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ 190 200 210 220 230 >>CCDS11833.1 TGIF1 gene_id:7050|Hs108|chr18 (272 aa) initn: 762 init1: 515 opt: 533 Z-score: 458.3 bits: 92.4 E(32554): 3.3e-19 Smith-Waterman score: 661; 49.6% identity (64.7% similar) in 252 aa overlap (3-217:19-269) 10 20 30 40 pF1KB8 MSDS-DLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYN :: :. : . . .:::.::::::::::.::::::: :::: CCDS11 MKGKKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 AYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDV :::::::: :: ::.::.::.::::::::::::::::::::::::::::::::.: :.. CCDS11 AYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISET 70 80 90 100 110 120 110 120 130 140 pF1KB8 A-----------LPR-----------GSSPSVLAVSVPAPTNVLS-LSVCSMPLHSGQGE . .: : .:.. : :.. : :. :. :. CCDS11 SSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTA 130 140 150 160 170 180 150 160 170 180 pF1KB8 KPAAPFPR------GELESPKPLVTPGSTLTLLTRAEAGSPTG-------GLFNTPPPTP .:: :. . . ... . : : : : .: :::::::::: CCDS11 LKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTP 190 200 210 220 230 240 190 200 210 220 230 pF1KB8 PEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ :. .. :::.:::::.:::.:::::::: . CCDS11 PDLNQ-DFSGFQLLVDVALKRAAEMELQAKLTA 250 260 270 >>CCDS11832.1 TGIF1 gene_id:7050|Hs108|chr18 (286 aa) initn: 762 init1: 515 opt: 533 Z-score: 458.0 bits: 92.4 E(32554): 3.4e-19 Smith-Waterman score: 661; 49.6% identity (64.7% similar) in 252 aa overlap (3-217:33-283) 10 20 30 pF1KB8 MSDS-DLGEDEGLLSLAGKRKRRGNLPKESVK :: :. : . . .:::.::::::::::. CCDS11 CSGKSCALARSSLTSSQGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQ 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 ILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQF ::::::: :::::::::::: :: ::.::.::.:::::::::::::::::::::::::: CCDS11 ILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQF 70 80 90 100 110 120 100 110 120 pF1KB8 TISRRGGKASDVA-----------LPR-----------GSSPSVLAVSVPAPTNVLS-LS ::::::.: :... .: : .:.. : :.. : :. CCDS11 TISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLA 130 140 150 160 170 180 130 140 150 160 170 pF1KB8 VCSMPLHSGQGEKPAAPFPR------GELESPKPLVTPGSTLTLLTRAEAGSPTG----- :. :. .:: :. . . ... . : : : : .: CCDS11 RPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNT 190 200 210 220 230 240 180 190 200 210 220 230 pF1KB8 --GLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSEN :::::::::::. .. :::.:::::.:::.:::::::: . CCDS11 QSGLFNTPPPTPPDLNQ-DFSGFQLLVDVALKRAAEMELQAKLTA 250 260 270 280 pF1KB8 PQ >>CCDS11835.1 TGIF1 gene_id:7050|Hs108|chr18 (252 aa) initn: 762 init1: 515 opt: 532 Z-score: 457.9 bits: 92.2 E(32554): 3.5e-19 Smith-Waterman score: 660; 49.8% identity (64.7% similar) in 249 aa overlap (5-217:6-249) 10 20 30 40 50 pF1KB8 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTN ::. . : .:::.::::::::::.::::::: :::::::::::: :: ::. CCDS11 MDIPLDLSSSAG----SGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTH 10 20 30 40 50 60 70 80 90 100 pF1KB8 LSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVA-----------LPR- ::.::.::::::::::::::::::::::::::::::::.: :... .: CCDS11 LSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPAL 60 70 80 90 100 110 110 120 130 140 150 pF1KB8 ----------GSSPSVLAVSVPAPTNVLS-LSVCSMPLHSGQGEKPAAPFPR------GE : .:.. : :.. : :. :. :. .:: :. CCDS11 EETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQ 120 130 140 150 160 170 160 170 180 190 200 pF1KB8 LESPKPLVTPGSTLTLLTRAEAGSPTG-------GLFNTPPPTPPEQDKEDFSSFQLLVE . . ... . : : : : .: :::::::::::. .. :::.:::::. CCDS11 NTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQ-DFSGFQLLVD 180 190 200 210 220 230 210 220 230 pF1KB8 VALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ :::.:::::::: . CCDS11 VALKRAAEMELQAKLTA 240 250 >>CCDS11834.1 TGIF1 gene_id:7050|Hs108|chr18 (401 aa) initn: 725 init1: 515 opt: 533 Z-score: 455.9 bits: 92.5 E(32554): 4.5e-19 Smith-Waterman score: 661; 49.6% identity (64.7% similar) in 252 aa overlap (3-217:148-398) 10 20 30 pF1KB8 MSDS-DLGEDEGLLSLAGKRKRRGNLPKESVK :: :. : . . .:::.::::::::::. CCDS11 QGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQ 120 130 140 150 160 170 40 50 60 70 80 90 pF1KB8 ILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQF ::::::: :::::::::::: :: ::.::.::.:::::::::::::::::::::::::: CCDS11 ILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQF 180 190 200 210 220 230 100 110 120 pF1KB8 TISRRGGKASDVA-----------LPR-----------GSSPSVLAVSVPAPTNVLS-LS ::::::.: :... .: : .:.. : :.. : :. CCDS11 TISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLA 240 250 260 270 280 290 130 140 150 160 170 pF1KB8 VCSMPLHSGQGEKPAAPFPR------GELESPKPLVTPGSTLTLLTRAEAGSPTG----- :. :. .:: :. . . ... . : : : : .: CCDS11 RPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNT 300 310 320 330 340 350 180 190 200 210 220 230 pF1KB8 --GLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSEN :::::::::::. .. :::.:::::.:::.:::::::: . CCDS11 QSGLFNTPPPTPPDLNQ-DFSGFQLLVDVALKRAAEMELQAKLTA 360 370 380 390 400 pF1KB8 PQ >>CCDS58772.1 C20orf24 gene_id:100527943|Hs108|chr20 (155 aa) initn: 415 init1: 415 opt: 418 Z-score: 366.1 bits: 74.5 E(32554): 4.5e-14 Smith-Waterman score: 418; 89.2% identity (90.5% similar) in 74 aa overlap (1-69:1-74) 10 20 30 40 50 60 pF1KB8 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 SVLQ-----ICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLA :::: . :: CCDS58 SVLQDEFLDVIYWFRQIIAVVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDE 70 80 90 100 110 120 >>CCDS14459.1 TGIF2LX gene_id:90316|Hs108|chrX (241 aa) initn: 498 init1: 358 opt: 416 Z-score: 361.8 bits: 74.3 E(32554): 7.8e-14 Smith-Waterman score: 531; 44.7% identity (68.3% similar) in 208 aa overlap (18-221:50-240) 10 20 30 40 pF1KB8 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPS :.::.:::: :::::::::.: ::..:::: CCDS14 PAKTQSPAQDTSIMSRNNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPS 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB8 EQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPR :.:: :: .::::.::: :::::::::.:::::.. .:: :... :: . .. . CCDS14 EEEKQMLSEKTNLSLLQISNWFINARRRILPDMLQQRRNDP---IIGHKTGKDAHATHLQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB8 GSSPSVLAVSVPA-PTNVLSLSVCSMPLHSGQGEKPAAPFPRGEL---ESPKPLVTPGST .. :: : : :. : :: :: : :.:.:.. ..: : .:.. CCDS14 STEASVPAKSGPSGPDNVQSL--------------PLWPLPKGQMSREKQPDPESAPSQK 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 LTLLTRAEAGSPTGGLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLP :: ... . .. . : ... ::::: :::..:.:::::.::.:.:.:. CCDS14 LTGIAQPKKKVKVSVTSPSSPELVSPEEHADFSSFLLLVDAAVQRAAELELEKKQEPNP 190 200 210 220 230 240 230 pF1KB8 LLHTPIPLVSENPQ >>CCDS14775.1 TGIF2LY gene_id:90655|Hs108|chrY (185 aa) initn: 352 init1: 352 opt: 369 Z-score: 324.4 bits: 67.0 E(32554): 9.6e-12 Smith-Waterman score: 369; 52.2% identity (75.2% similar) in 113 aa overlap (18-130:50-159) 10 20 30 40 pF1KB8 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPS :.::.:::: :::::::::.: ::..:::: CCDS14 PAKTQSPAQDTSIMSRNNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPS 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB8 EQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPR :.:: :: .::::.:.: :::::::::.:::::.. .:: :... :: . .. . CCDS14 EEEKQMLSEKTNLSLLRISNWFINARRRILPDMLQQRRNDP---IIGHKTGKDAHATHLQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB8 GSSPSVLAVSVPAPTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLL .. :: : : :. .. . : CCDS14 STEASVPAKSGPVVQTMYKACPCGPCQRARCQERSNQIRSRPLARSSPE 140 150 160 170 180 237 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:25:39 2016 done: Fri Nov 4 16:25:39 2016 Total Scan time: 2.780 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]