FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8905, 237 aa 1>>>pF1KB8905 237 - 237 aa - 237 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0816+/-0.000684; mu= 9.1654+/- 0.042 mean_var=155.8645+/-30.964, 0's: 0 Z-trim(116.5): 12 B-trim: 0 in 0/54 Lambda= 0.102731 statistics sampled from 17085 (17095) to 17085 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.525), width: 16 Scan time: 2.790 The best scores are: opt bits E(32554) CCDS9608.1 NRL gene_id:4901|Hs108|chr14 ( 237) 1592 246.4 1.2e-65 CCDS34955.1 MAFA gene_id:389692|Hs108|chr8 ( 353) 456 78.2 7.9e-15 CCDS13311.1 MAFB gene_id:9935|Hs108|chr20 ( 323) 439 75.6 4.3e-14 CCDS42198.1 MAF gene_id:4094|Hs108|chr16 ( 373) 432 74.6 9.7e-14 CCDS10928.1 MAF gene_id:4094|Hs108|chr16 ( 403) 432 74.7 1e-13 >>CCDS9608.1 NRL gene_id:4901|Hs108|chr14 (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1291.8 bits: 246.4 E(32554): 1.2e-65 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>CCDS34955.1 MAFA gene_id:389692|Hs108|chr8 (353 aa) initn: 686 init1: 430 opt: 456 Z-score: 379.7 bits: 78.2 E(32554): 7.9e-15 Smith-Waterman score: 531; 42.2% identity (63.7% similar) in 256 aa overlap (27-229:73-325) 10 20 30 40 50 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEP :. : : .. ::. ...: :. . : CCDS34 HRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPS-GGP 50 60 70 80 90 100 60 70 80 90 100 pF1KB8 GMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQG----------PVP : ::.: : .:.::.:::.. :..:. :::.:.::.:.: : :.: :. CCDS34 GAVGGTSG-KPALEDLYWMSGYQHHLNP-EALNLTPEDAVEALIGSGHHGAHHGAHHPAA 110 120 130 140 150 110 120 pF1KB8 VD------GP----------------HG-------------------YYPGSPEETGA-Q . :: :: .. :. . :: . CCDS34 AAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGH 160 170 180 190 200 210 130 140 150 160 170 180 pF1KB8 HVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQR ::.: ::::: ::::::::::::::: ...:..::::.:::::::::::.:: ::.::: CCDS34 HVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQR 220 230 240 250 260 270 190 200 210 220 230 pF1KB8 RGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTS-SGPGSGDPSHLFL . ::.:. .: .:.. :. ::.:::.:::::: . ..:.. .:::: CCDS34 HILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQ 280 290 300 310 320 330 CCDS34 AGPGGAKGTADFFL 340 350 >>CCDS13311.1 MAFB gene_id:9935|Hs108|chr20 (323 aa) initn: 782 init1: 423 opt: 439 Z-score: 366.5 bits: 75.6 E(32554): 4.3e-14 Smith-Waterman score: 501; 41.0% identity (58.2% similar) in 261 aa overlap (33-226:53-305) 10 20 30 40 50 60 pF1KB8 LPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVGAT : ... ::: :::: ::.:: : : CCDS13 DFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFS-P-----T 30 40 50 60 70 70 80 90 100 pF1KB8 EGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVP-----VDG-------- : . ::.:::.:. ::.. :::.:.::.:.: : :. ::: :. CCDS13 E-QKTHLEDLYWMASNYQQMNP-EALNLTPEDAVEALIGSHPVPQPLQSFDSFRGAHHHH 80 90 100 110 120 130 110 120 pF1KB8 ------PHGYYPGS-----------------------PEETGAQHVQ------------- :: :::. : ..:. .: CCDS13 HHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHPGPGPHA 140 150 160 170 180 190 130 140 150 160 170 pF1KB8 ------------LAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQA . .:::: :::::::::::.::: .::..::::.:::::::::::. CCDS13 TASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQS 200 210 220 230 240 250 180 190 200 210 220 230 pF1KB8 CRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHL :: ::.::.. :: :...: :.. :. ::.::::::: ::..:..:..:: CCDS13 CRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGFREAGSTSD 260 270 280 290 300 310 pF1KB8 FL CCDS13 SPSSPEFFL 320 >>CCDS42198.1 MAF gene_id:4094|Hs108|chr16 (373 aa) initn: 730 init1: 413 opt: 432 Z-score: 360.1 bits: 74.6 E(32554): 9.7e-14 Smith-Waterman score: 432; 50.7% identity (71.5% similar) in 144 aa overlap (83-226:212-355) 60 70 80 90 100 110 pF1KB8 FSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHG ::: : : .: : : : : : CCDS42 HHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAG 190 200 210 220 230 240 120 130 140 150 160 170 pF1KB8 YYPGSPEETGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGY . . .: ... .:::: ::.:::::::::::: ...:..::::.::::::::: CCDS42 AGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGY 250 260 270 280 290 300 180 190 200 210 220 230 pF1KB8 AQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDP ::.:: ::.:::. ::.:. .: :.: :. :..::.:::: :: . ..:.::: CCDS42 AQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENGS 310 320 330 340 350 360 pF1KB8 SHLFL CCDS42 SSDNPSSPEFFM 370 >>CCDS10928.1 MAF gene_id:4094|Hs108|chr16 (403 aa) initn: 730 init1: 413 opt: 432 Z-score: 359.7 bits: 74.7 E(32554): 1e-13 Smith-Waterman score: 432; 50.7% identity (71.5% similar) in 144 aa overlap (83-226:212-355) 60 70 80 90 100 110 pF1KB8 FSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHG ::: : : .: : : : : : CCDS10 HHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAG 190 200 210 220 230 240 120 130 140 150 160 170 pF1KB8 YYPGSPEETGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGY . . .: ... .:::: ::.:::::::::::: ...:..::::.::::::::: CCDS10 AGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGY 250 260 270 280 290 300 180 190 200 210 220 230 pF1KB8 AQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDP ::.:: ::.:::. ::.:. .: :.: :. :..::.:::: :: . ..:.::: CCDS10 AQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENGS 310 320 330 340 350 360 pF1KB8 SHLFL CCDS10 SSDNPSSPEFFITEPTRKLEPSVGYATFWKPQHRVLTSVFTK 370 380 390 400 237 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:45:55 2016 done: Sat Nov 5 00:45:56 2016 Total Scan time: 2.790 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]