FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8905, 237 aa 1>>>pF1KB8905 237 - 237 aa - 237 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0261+/-0.000275; mu= 9.6037+/- 0.017 mean_var=164.4013+/-32.603, 0's: 0 Z-trim(123.8): 27 B-trim: 0 in 0/60 Lambda= 0.100028 statistics sampled from 44316 (44348) to 44316 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.52), width: 16 Scan time: 7.070 The best scores are: opt bits E(85289) XP_011535104 (OMIM: 162080,613750) PREDICTED: neur ( 237) 1592 240.4 2.1e-63 XP_005267766 (OMIM: 162080,613750) PREDICTED: neur ( 237) 1592 240.4 2.1e-63 XP_011535106 (OMIM: 162080,613750) PREDICTED: neur ( 237) 1592 240.4 2.1e-63 XP_005267767 (OMIM: 162080,613750) PREDICTED: neur ( 237) 1592 240.4 2.1e-63 XP_005267765 (OMIM: 162080,613750) PREDICTED: neur ( 237) 1592 240.4 2.1e-63 XP_011535107 (OMIM: 162080,613750) PREDICTED: neur ( 237) 1592 240.4 2.1e-63 NP_006168 (OMIM: 162080,613750) neural retina-spec ( 237) 1592 240.4 2.1e-63 XP_011535103 (OMIM: 162080,613750) PREDICTED: neur ( 339) 1592 240.5 2.7e-63 XP_016876839 (OMIM: 162080,613750) PREDICTED: neur ( 132) 715 113.6 1.7e-25 XP_011535108 (OMIM: 162080,613750) PREDICTED: neur ( 234) 715 113.8 2.6e-25 NP_963883 (OMIM: 610303) transcription factor MafA ( 353) 456 76.6 6.2e-14 NP_005452 (OMIM: 166300,608968,617041) transcripti ( 323) 439 74.1 3.2e-13 NP_001026974 (OMIM: 177075,601088,610202) transcri ( 373) 432 73.2 7.1e-13 XP_016878722 (OMIM: 177075,601088,610202) PREDICTE ( 383) 432 73.2 7.3e-13 XP_016878724 (OMIM: 177075,601088,610202) PREDICTE ( 383) 432 73.2 7.3e-13 XP_016878723 (OMIM: 177075,601088,610202) PREDICTE ( 383) 432 73.2 7.3e-13 NP_005351 (OMIM: 177075,601088,610202) transcripti ( 403) 432 73.2 7.5e-13 NP_001155045 (OMIM: 604877) transcription factor M ( 164) 287 51.9 8e-07 NP_036455 (OMIM: 604877) transcription factor MafF ( 164) 287 51.9 8e-07 NP_001155044 (OMIM: 604877) transcription factor M ( 164) 287 51.9 8e-07 NP_116100 (OMIM: 602020) transcription factor MafG ( 162) 278 50.6 1.9e-06 NP_002350 (OMIM: 602020) transcription factor MafG ( 162) 278 50.6 1.9e-06 XP_011521880 (OMIM: 602020) PREDICTED: transcripti ( 162) 278 50.6 1.9e-06 XP_006715836 (OMIM: 600197) PREDICTED: transcripti ( 156) 276 50.3 2.3e-06 NP_002351 (OMIM: 600197) transcription factor MafK ( 156) 276 50.3 2.3e-06 XP_005249908 (OMIM: 600197) PREDICTED: transcripti ( 156) 276 50.3 2.3e-06 NP_001155046 (OMIM: 604877) transcription factor M ( 135) 264 48.5 7e-06 >>XP_011535104 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>XP_005267766 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>XP_011535106 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>XP_005267767 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>XP_005267765 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>XP_011535107 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>NP_006168 (OMIM: 162080,613750) neural retina-specific (237 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1259.3 bits: 240.4 E(85289): 2.1e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237) 10 20 30 40 50 60 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 190 200 210 220 230 >>XP_011535103 (OMIM: 162080,613750) PREDICTED: neural r (339 aa) initn: 1592 init1: 1592 opt: 1592 Z-score: 1257.3 bits: 240.5 E(85289): 2.7e-63 Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:103-339) 10 20 30 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREPSEG :::::::::::::::::::::::::::::: XP_011 LAEAESRRAPLAAPRGRAQRKVHSSQPSSRMALPPSPLAMEYVNDFDLMKFEVKREPSEG 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB8 RPGPPTASLGSTPYSSVPPSPTFSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPGPPTASLGSTPYSSVPPSPTFSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGL 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB8 SPEEAMELLQGQGPVPVDGPHGYYPGSPEETGAQHVQLAERFSDAALVSMSVRELNRQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEEAMELLQGQGPVPVDGPHGYYPGSPEETGAQHVQLAERFSDAALVSMSVRELNRQLR 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB8 GCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLAR 260 270 280 290 300 310 220 230 pF1KB8 ERDLYKARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::::::::: XP_011 ERDLYKARCDRLTSSGPGSGDPSHLFL 320 330 >>XP_016876839 (OMIM: 162080,613750) PREDICTED: neural r (132 aa) initn: 738 init1: 715 opt: 715 Z-score: 578.5 bits: 113.6 E(85289): 1.7e-25 Smith-Waterman score: 715; 99.1% identity (100.0% similar) in 111 aa overlap (127-237:22-132) 100 110 120 130 140 150 pF1KB8 ELLQGQGPVPVDGPHGYYPGSPEETGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDE .::::::::::::::::::::::::::::: XP_016 MALPPSPLAMEYVNDFDLMKFELAERFSDAALVSMSVRELNRQLRGCGRDE 10 20 30 40 50 160 170 180 190 200 210 pF1KB8 ALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYK 60 70 80 90 100 110 220 230 pF1KB8 ARCDRLTSSGPGSGDPSHLFL ::::::::::::::::::::: XP_016 ARCDRLTSSGPGSGDPSHLFL 120 130 >>XP_011535108 (OMIM: 162080,613750) PREDICTED: neural r (234 aa) initn: 744 init1: 715 opt: 715 Z-score: 575.4 bits: 113.8 E(85289): 2.6e-25 Smith-Waterman score: 721; 61.4% identity (71.8% similar) in 220 aa overlap (22-237:35-234) 10 20 30 40 pF1KB8 MALPPSPLAMEYVNDFDLMKFEVKREP-SEGR-PGPPTASLGSTPYSS--V ::. : : :: :. : . :. .:: XP_011 GSAERSEEREEVLRVADRDRAVRGERGREGEVQAETRSTGRLPSQETRGAGGWTHSSRPC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PPSPTFSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPV :: : . : .. .:. : : : :... ... : : : : :. XP_011 PPPPRM---GNLAEAESRRAPLAAPRGRA--QRKVHSSQ-----PSSRMAL----PPSPL 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 DGPHGYYPGSPEETGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTL . .. .. .:::::::::::::::::::::::::::::::::::::::: XP_011 AMEY------VNDFDLMKFELAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTL 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 KNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGP 170 180 190 200 210 220 230 pF1KB8 GSGDPSHLFL :::::::::: XP_011 GSGDPSHLFL 230 237 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:45:56 2016 done: Sat Nov 5 00:45:57 2016 Total Scan time: 7.070 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]