FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8907, 239 aa 1>>>pF1KB8907 239 - 239 aa - 239 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6367+/-0.000256; mu= 14.1064+/- 0.016 mean_var=88.5760+/-17.832, 0's: 0 Z-trim(121.6): 4 B-trim: 0 in 0/55 Lambda= 0.136275 statistics sampled from 38506 (38511) to 38506 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.452), width: 16 Scan time: 7.700 The best scores are: opt bits E(85289) NP_001013633 (OMIM: 616129) leucine rich adaptor p ( 239) 1601 323.7 1.8e-88 NP_981948 (OMIM: 616130) leucine rich adaptor prot ( 228) 282 64.4 2e-10 >>NP_001013633 (OMIM: 616129) leucine rich adaptor prote (239 aa) initn: 1601 init1: 1601 opt: 1601 Z-score: 1709.5 bits: 323.7 E(85289): 1.8e-88 Smith-Waterman score: 1601; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239) 10 20 30 40 50 60 pF1KB8 MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGECELGTSGALLLPGASSTGHDLGDKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGECELGTSGALLLPGASSTGHDLGDKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALKMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALKMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RSRRGSWDSLPDTSTTDRLDSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRRGSWDSLPDTSTTDRLDSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGER 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ARTEVDVAATRLGSLRAVWKPPGERLQGGPPESPEDESAKLGFEAHWFWEQCQDDVTFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARTEVDVAATRLGSLRAVWKPPGERLQGGPPESPEDESAKLGFEAHWFWEQCQDDVTFL 190 200 210 220 230 >>NP_981948 (OMIM: 616130) leucine rich adaptor protein (228 aa) initn: 391 init1: 186 opt: 282 Z-score: 308.3 bits: 64.4 E(85289): 2e-10 Smith-Waterman score: 329; 37.3% identity (61.1% similar) in 193 aa overlap (10-161:7-196) 10 20 30 pF1KB8 MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGE------------------------CE :::::.: :.:::.::.:.:.:::: : NP_981 MEDSPLPDLRDIELKLGRKVPESLVRSLRGEEPVPRERDRDPCGGSGGGGGGGGGCS 10 20 30 40 50 40 50 60 70 pF1KB8 LGTSGALLLPGASST-------GHDLGD----------KIMALKMELAYLRAIDVKILQQ ..: . :. ::. : :. :. :..:.. ::: ::....: NP_981 SSSSYCSFPPSLSSSSSSSPTSGSPRGSHSSALERLETKLHLLRQEMVNLRATDVRLMRQ 60 70 80 90 100 110 80 90 100 110 120 130 pF1KB8 LVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPGRSRRGSWDSLPDTSTTDRL :...::.::...:..::..:.::. :::..: :: : . : :::..:: : : : : NP_981 LLVINESIESIKWMIEEKATITSRGSSLSGSLCSLLE-SQSTSLRGSYNSLHDGS--DGL 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB8 DSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGERARTEVDVAATRLGSLRAVW :..:.::.:::.: . .: : NP_981 DGISVGSYLDTLADDVPGHQTPSDLDQFSDSSLIEDSQALHKRPKLDSEYYCFG 180 190 200 210 220 239 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:46:31 2016 done: Sat Nov 5 00:46:33 2016 Total Scan time: 7.700 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]