FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8908, 242 aa 1>>>pF1KB8908 242 - 242 aa - 242 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1661+/-0.000319; mu= 7.2801+/- 0.020 mean_var=172.7123+/-34.602, 0's: 0 Z-trim(121.4): 212 B-trim: 330 in 2/53 Lambda= 0.097592 statistics sampled from 37656 (37943) to 37656 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.445), width: 16 Scan time: 6.180 The best scores are: opt bits E(85289) NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 1678 247.5 1.5e-65 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 1009 153.3 3.5e-37 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 997 151.7 1.1e-36 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 997 151.7 1.1e-36 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 796 123.4 4.2e-28 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 784 121.7 1.4e-27 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 536 86.4 2.2e-17 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 452 74.9 1.3e-13 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 452 74.9 1.3e-13 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 452 74.9 1.3e-13 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 452 75.0 1.6e-13 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 435 72.5 7.1e-13 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 417 69.9 4e-12 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 417 70.0 4.2e-12 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 410 68.8 6.1e-12 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 408 68.7 1e-11 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 349 60.4 3.1e-09 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 346 60.0 4.7e-09 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 344 59.8 5.7e-09 NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 322 56.6 4.8e-08 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 318 56.1 7.1e-08 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 318 56.1 7.1e-08 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 313 55.4 1.1e-07 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 310 54.9 1.5e-07 NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 311 55.2 1.7e-07 NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 302 53.9 4.1e-07 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 297 53.1 5.3e-07 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 297 53.1 5.6e-07 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 298 53.4 5.7e-07 NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 287 51.8 1.8e-06 NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 287 51.9 2e-06 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 280 50.8 3e-06 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 277 50.5 5e-06 NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 272 49.7 7.5e-06 NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 270 49.4 8.5e-06 NP_005513 (OMIM: 142955,601536) homeobox protein H ( 335) 268 49.2 1.1e-05 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 264 48.5 1.5e-05 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 257 47.7 3.9e-05 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 257 47.7 3.9e-05 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 249 46.3 5.7e-05 NP_067016 (OMIM: 142988) homeobox protein Hox-D12 ( 270) 249 46.4 6.1e-05 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 249 46.5 7.4e-05 NP_059106 (OMIM: 142976,614931) homeobox protein H ( 330) 248 46.3 7.7e-05 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 246 46.0 8.8e-05 >>NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [Homo (242 aa) initn: 1678 init1: 1678 opt: 1678 Z-score: 1297.7 bits: 247.5 E(85289): 1.5e-65 Smith-Waterman score: 1678; 100.0% identity (100.0% similar) in 242 aa overlap (1-242:1-242) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN 190 200 210 220 230 240 pF1KB8 KD :: NP_073 KD >>XP_005257343 (OMIM: 142963) PREDICTED: homeobox protei (242 aa) initn: 966 init1: 579 opt: 1009 Z-score: 788.6 bits: 153.3 E(85289): 3.5e-37 Smith-Waterman score: 1009; 62.3% identity (82.0% similar) in 244 aa overlap (1-241:1-238) 10 20 30 40 50 pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP--GGSAPGFQHASHHVQD ::::::: ::::::.::::.: :::: : :..: ..:::: ::: ::: :. .:. XP_005 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGS---FQHPSQ-IQE 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 FFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSA :.: : :..:.. ::::::...:::: ..::::. : ::::.::: . ..::: ::: .: XP_005 FYH-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 NTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKR .. .: .:. ::. .::::::.: ::: ::::::::::::::::::::::::::: XP_005 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 RIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEEK ::::::::::::::::::::::::::::::::::.:... ..:..:.. :. . .: XP_005 RIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEG 180 190 200 210 220 230 240 pF1KB8 EENKD . .: XP_005 DAQKGDKK 240 >>NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [Homo (243 aa) initn: 947 init1: 645 opt: 997 Z-score: 779.5 bits: 151.7 E(85289): 1.1e-36 Smith-Waterman score: 997; 62.0% identity (81.6% similar) in 245 aa overlap (1-241:1-239) 10 20 30 40 50 pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP--GGSAPGFQHASHHVQD ::::::: ::::::.::::.: :::: : :..: ..:::: ::: ::: :. .:. NP_076 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGS---FQHPSQ-IQE 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 FFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSA :.: : :..:.. ::::::...:::: ..::::. : ::::.::: . ..::: ::: .: NP_076 FYH-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 NTNSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRK .. .: .:. ::. .::::::.: ::: :::::::::::::::::::::::::: NP_076 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEE :::::::::::::::::::::::::::::::::::.:... ..:..:.. :. . .: NP_076 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADE 180 190 200 210 220 230 240 pF1KB8 KEENKD . .: NP_076 GDAQKGDKK 240 >>XP_016880053 (OMIM: 142963) PREDICTED: homeobox protei (243 aa) initn: 947 init1: 645 opt: 997 Z-score: 779.5 bits: 151.7 E(85289): 1.1e-36 Smith-Waterman score: 997; 62.0% identity (81.6% similar) in 245 aa overlap (1-241:1-239) 10 20 30 40 50 pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP--GGSAPGFQHASHHVQD ::::::: ::::::.::::.: :::: : :..: ..:::: ::: ::: :. .:. XP_016 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGS---FQHPSQ-IQE 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 FFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSA :.: : :..:.. ::::::...:::: ..::::. : ::::.::: . ..::: ::: .: XP_016 FYH-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 NTNSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRK .. .: .:. ::. .::::::.: ::: :::::::::::::::::::::::::: XP_016 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEE :::::::::::::::::::::::::::::::::::.:... ..:..:.. :. . .: XP_016 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADE 180 190 200 210 220 230 240 pF1KB8 KEENKD . .: XP_016 GDAQKGDKK 240 >>NP_001186675 (OMIM: 142985) homeobox protein Hox-D8 is (289 aa) initn: 893 init1: 601 opt: 796 Z-score: 625.6 bits: 123.4 E(85289): 4.2e-28 Smith-Waterman score: 866; 54.3% identity (69.1% similar) in 265 aa overlap (15-238:23-285) 10 20 30 40 pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP----GGSAPG :::...:.::::.: :: :: . . :.:: : NP_001 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 10 20 30 40 50 60 50 60 70 pF1KB8 FQHASHHV----------------------QDFFHHGTSGISNSGYQQNP---------- : :: .. :..:: : .: ..:: : NP_001 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPG-GGSPAAAYQAAPPPPPHPPPPP 70 80 90 100 110 80 90 100 110 120 130 pF1KB8 ----CS-LSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ :. ..:::. .:::::. : :: .. .:::: .:::::::::.. : .: :::: NP_001 PPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSG-NIGEDPDHLNQ 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB8 NSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER .:::: :::::::.::::: :::::::.:::::::::::::::::::::::::::.:::: NP_001 SSSPSQMFPWMRPQAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER 180 190 200 210 220 230 200 210 220 230 240 pF1KB8 QVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD :::::::::::::::::::::.: .:.: : : .: .: ::.. : NP_001 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN 240 250 260 270 280 >>NP_062458 (OMIM: 142985) homeobox protein Hox-D8 isofo (290 aa) initn: 885 init1: 646 opt: 784 Z-score: 616.4 bits: 121.7 E(85289): 1.4e-27 Smith-Waterman score: 854; 54.1% identity (68.8% similar) in 266 aa overlap (15-238:23-286) 10 20 30 40 pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP----GGSAPG :::...:.::::.: :: :: . . :.:: : NP_062 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 10 20 30 40 50 60 50 60 70 pF1KB8 FQHASHHV----------------------QDFFHHGTSGISNSGYQQNP---------- : :: .. :..:: : .: ..:: : NP_062 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPG-GGSPAAAYQAAPPPPPHPPPPP 70 80 90 100 110 80 90 100 110 120 130 pF1KB8 ----CS-LSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ :. ..:::. .:::::. : :: .. .:::: .:::::::::.. : .: :::: NP_062 PPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSG-NIGEDPDHLNQ 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB8 NSSPSLMFPWMRPHA-PGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTE .:::: :::::::.: :::: :::::::.:::::::::::::::::::::::::::.::: NP_062 SSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTE 180 190 200 210 220 230 200 210 220 230 240 pF1KB8 RQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD ::::::::::::::::::::::.: .:.: : : .: .: ::.. : NP_062 RQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN 240 250 260 270 280 290 >>NP_001186676 (OMIM: 142985) homeobox protein Hox-D8 is (106 aa) initn: 540 init1: 483 opt: 536 Z-score: 433.2 bits: 86.4 E(85289): 2.2e-17 Smith-Waterman score: 536; 79.4% identity (89.2% similar) in 102 aa overlap (138-238:1-102) 110 120 130 140 150 160 pF1KB8 VVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHA-PGRRSGRQTYSRYQTLELEK :::::::.: :::: :::::::.::::::: NP_001 MFPWMRPQAAPGRRRGRQTYSRFQTLELEK 10 20 30 170 180 190 200 210 220 pF1KB8 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEG ::::::::::::::::::::.:::::::::::::::::::::::::.: .:.: : : NP_001 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETK 40 50 60 70 80 90 230 240 pF1KB8 NEEEEKEEEEKEENKD .: .: ::.. : NP_001 KEAQELEEDRAEGLTN 100 >>XP_005257341 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 443 init1: 342 opt: 452 Z-score: 365.2 bits: 74.9 E(85289): 1.3e-13 Smith-Waterman score: 452; 39.8% identity (60.2% similar) in 241 aa overlap (1-224:1-224) 10 20 30 40 50 pF1KB8 MSSYFVNPLFSKYKAG--ESL--EPAYYDCRFPQSVGRSHALVYGPG-GSAPGFQHASHH ::::::: : :. ::. . :. . . . : . :::: :. :: .:.. XP_005 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPL-RHYPAPYGPGPGQDKGFATSSYY 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 VQDFFHHGTSGISNSGY-QQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDC ...:: . ::. .: : :: : .: ::... : XP_005 PP----------AGGGYGRAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRK 60 70 80 90 100 120 130 140 150 160 pF1KB8 KSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGRRSGRQTYSRYQTLELEK .. :. .: :. . .. :.: ..:::. .:. : :::::.::::::::: XP_005 SDCAQDKSVFGETEEQKCSTP--VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEK 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN---NKDKLPGARDEEKVE :: .: ::::.::::..::: :::::.::::::::::::::. . ..: . ..::: XP_005 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA 170 180 190 200 210 220 230 240 pF1KB8 EEGNEEEEKEEEEKEENKD : XP_005 E >>XP_005257340 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 443 init1: 342 opt: 452 Z-score: 365.2 bits: 74.9 E(85289): 1.3e-13 Smith-Waterman score: 452; 39.8% identity (60.2% similar) in 241 aa overlap (1-224:1-224) 10 20 30 40 50 pF1KB8 MSSYFVNPLFSKYKAG--ESL--EPAYYDCRFPQSVGRSHALVYGPG-GSAPGFQHASHH ::::::: : :. ::. . :. . . . : . :::: :. :: .:.. XP_005 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPL-RHYPAPYGPGPGQDKGFATSSYY 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 VQDFFHHGTSGISNSGY-QQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDC ...:: . ::. .: : :: : .: ::... : XP_005 PP----------AGGGYGRAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRK 60 70 80 90 100 120 130 140 150 160 pF1KB8 KSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGRRSGRQTYSRYQTLELEK .. :. .: :. . .. :.: ..:::. .:. : :::::.::::::::: XP_005 SDCAQDKSVFGETEEQKCSTP--VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEK 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN---NKDKLPGARDEEKVE :: .: ::::.::::..::: :::::.::::::::::::::. . ..: . ..::: XP_005 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA 170 180 190 200 210 220 230 240 pF1KB8 EEGNEEEEKEEEEKEENKD : XP_005 E >>NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [Homo (224 aa) initn: 443 init1: 342 opt: 452 Z-score: 365.2 bits: 74.9 E(85289): 1.3e-13 Smith-Waterman score: 452; 39.8% identity (60.2% similar) in 241 aa overlap (1-224:1-224) 10 20 30 40 50 pF1KB8 MSSYFVNPLFSKYKAG--ESL--EPAYYDCRFPQSVGRSHALVYGPG-GSAPGFQHASHH ::::::: : :. ::. . :. . . . : . :::: :. :: .:.. NP_061 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPL-RHYPAPYGPGPGQDKGFATSSYY 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 VQDFFHHGTSGISNSGY-QQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDC ...:: . ::. .: : :: : .: ::... : NP_061 PP----------AGGGYGRAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRK 60 70 80 90 100 120 130 140 150 160 pF1KB8 KSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGRRSGRQTYSRYQTLELEK .. :. .: :. . .. :.: ..:::. .:. : :::::.::::::::: NP_061 SDCAQDKSVFGETEEQKCSTP--VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEK 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN---NKDKLPGARDEEKVE :: .: ::::.::::..::: :::::.::::::::::::::. . ..: . ..::: NP_061 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA 170 180 190 200 210 220 230 240 pF1KB8 EEGNEEEEKEEEEKEENKD : NP_061 E 242 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:26:46 2016 done: Fri Nov 4 16:26:47 2016 Total Scan time: 6.180 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]