FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8909, 244 aa 1>>>pF1KB8909 244 - 244 aa - 244 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2831+/-0.000901; mu= 1.9598+/- 0.053 mean_var=243.4958+/-53.436, 0's: 0 Z-trim(114.9): 780 B-trim: 834 in 1/51 Lambda= 0.082192 statistics sampled from 14501 (15438) to 14501 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.474), width: 16 Scan time: 2.400 The best scores are: opt bits E(32554) CCDS6633.1 KLF9 gene_id:687|Hs108|chr9 ( 244) 1700 213.7 8.9e-56 CCDS10025.1 KLF13 gene_id:51621|Hs108|chr15 ( 288) 608 84.3 9.5e-17 CCDS12075.1 KLF16 gene_id:83855|Hs108|chr19 ( 252) 547 77.0 1.3e-14 CCDS5825.1 KLF14 gene_id:136259|Hs108|chr7 ( 323) 545 76.9 1.8e-14 CCDS47905.1 KLF10 gene_id:7071|Hs108|chr8 ( 469) 497 71.4 1.2e-12 CCDS6294.1 KLF10 gene_id:7071|Hs108|chr8 ( 480) 497 71.4 1.2e-12 CCDS5372.1 SP8 gene_id:221833|Hs108|chr7 ( 490) 484 69.9 3.7e-12 CCDS43555.1 SP8 gene_id:221833|Hs108|chr7 ( 508) 484 69.9 3.7e-12 CCDS46453.1 SP9 gene_id:100131390|Hs108|chr2 ( 484) 471 68.3 1.1e-11 CCDS44898.1 SP1 gene_id:6667|Hs108|chr12 ( 778) 473 68.8 1.2e-11 CCDS8857.1 SP1 gene_id:6667|Hs108|chr12 ( 785) 473 68.8 1.2e-11 CCDS54333.1 KLF11 gene_id:8462|Hs108|chr2 ( 495) 468 68.0 1.4e-11 CCDS1668.1 KLF11 gene_id:8462|Hs108|chr2 ( 512) 468 68.0 1.4e-11 CCDS33322.1 SP5 gene_id:389058|Hs108|chr2 ( 398) 456 66.4 3.2e-11 CCDS5373.1 SP4 gene_id:6671|Hs108|chr7 ( 784) 458 67.0 4.3e-11 CCDS3036.1 KLF15 gene_id:28999|Hs108|chr3 ( 416) 452 66.0 4.5e-11 CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX ( 359) 447 65.3 6.2e-11 CCDS73475.1 SP7 gene_id:121340|Hs108|chr12 ( 413) 446 65.3 7.4e-11 CCDS44897.1 SP7 gene_id:121340|Hs108|chr12 ( 431) 446 65.3 7.6e-11 CCDS46452.1 SP3 gene_id:6670|Hs108|chr2 ( 713) 450 66.0 7.7e-11 CCDS2254.1 SP3 gene_id:6670|Hs108|chr2 ( 781) 450 66.0 8.2e-11 >>CCDS6633.1 KLF9 gene_id:687|Hs108|chr9 (244 aa) initn: 1700 init1: 1700 opt: 1700 Z-score: 1114.8 bits: 213.7 E(32554): 8.9e-56 Smith-Waterman score: 1700; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244) 10 20 30 40 50 60 pF1KB8 MSAAAYMDFVAAQCLVSISNRAAVPEHGVAPDAERLRLPEREVTKEHGDPGDTWKDYCTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MSAAAYMDFVAAQCLVSISNRAAVPEHGVAPDAERLRLPEREVTKEHGDPGDTWKDYCTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSPEERQDPGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 VTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSPEERQDPGSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 PSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKKAL 190 200 210 220 230 240 pF1KB8 ANAL :::: CCDS66 ANAL >>CCDS10025.1 KLF13 gene_id:51621|Hs108|chr15 (288 aa) initn: 717 init1: 574 opt: 608 Z-score: 414.1 bits: 84.3 E(32554): 9.5e-17 Smith-Waterman score: 714; 45.6% identity (66.9% similar) in 263 aa overlap (1-235:1-259) 10 20 30 40 50 pF1KB8 MSAAAYMDFVAAQCLVSISNRAAV--PEHGVA--PD-AERLRLPEREVTKEHGDPGDTWK :.::::.: ::.::::.:.::.: :..: :. : : ..:. : : CCDS10 MAAAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERRDG----K 10 20 30 40 50 60 70 80 90 100 pF1KB8 DYCTLVTIAKSLLDLNKYRPIQTPS-----VCSDSLESP-------DEDMGSDSDVTTES : .: ..:. : :::. : .:. . . . ..: : . .. .. . CCDS10 DSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAA 60 70 80 90 100 110 110 120 130 140 150 pF1KB8 GSSPSHS---PEERQDPGSAPSPLSLLHPGV---AAKGK-----HASEKRHKCPYSGCGK ::. : :: .: :.: . .::. . .:. .. ...::: :.:: : CCDS10 PPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEK 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB8 VYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRF ::::::::::: :.::::::: :.: :: :::.:::::.::::::::::.: ::.::::: CCDS10 VYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRF 180 190 200 210 220 230 220 230 240 pF1KB8 MRSDHLTKHARRHTEFHPSMIKRSKKALANAL :::::::::::::..:::.:..: CCDS10 MRSDHLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP 240 250 260 270 280 >>CCDS12075.1 KLF16 gene_id:83855|Hs108|chr19 (252 aa) initn: 734 init1: 495 opt: 547 Z-score: 375.8 bits: 77.0 E(32554): 1.3e-14 Smith-Waterman score: 571; 43.9% identity (61.5% similar) in 244 aa overlap (1-235:1-219) 10 20 30 40 50 pF1KB8 MSAA-AYMDFVAAQCLVSISNRAAV------PEHGVAPDAE-RLRLPEREVTKEHGDPGD :::: : .:. ::. :..::. :.: :: :..: : .: .::... : :: CCDS12 MSAAVACVDYFAADVLMAISSGAVVHRGRPGPE-GAGPAAGLDVRAARREAASP-GTPGP 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 TWKDYCTLVTIAKSLLDLNKYRP-IQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSP :.. : . . :. .: .: :. : . :.:: . :: CCDS12 PPPP-----PAASGPGPGAAAAPHLLAASILADLRGGPGAAPGGASPA---SSSSAASSP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 EERQDPGSAPSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER . ::.::: :. : :.::. :.:.: ::::::.: :.::::: CCDS12 SSGRAPGAAPS---------------AAAKSHRCPFPDCAKAYYKSSHLKSHLRTHTGER 120 130 140 150 180 190 200 210 220 230 pF1KB8 PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPS :: : : : :::.:::::.::.:::::::.: :::: ::: :::::.:::::: :::. CCDS12 PFACDWQGCDKKFARSDELARHHRTHTGEKRFSCPLCSKRFTRSDHLAKHARRHPGFHPD 160 170 180 190 200 210 240 pF1KB8 MIKRSKKALANAL ...: CCDS12 LLRRPGARSTSPSDSLPCSLAGSPAPSPAPSPAPAGL 220 230 240 250 >>CCDS5825.1 KLF14 gene_id:136259|Hs108|chr7 (323 aa) initn: 778 init1: 534 opt: 545 Z-score: 373.2 bits: 76.9 E(32554): 1.8e-14 Smith-Waterman score: 545; 60.7% identity (78.7% similar) in 122 aa overlap (118-238:172-291) 90 100 110 120 130 140 pF1KB8 SPDEDMGSDSDVTTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKRHKCPY :..:.: . : .. . :::.::. CCDS58 ESSSDAPAVPSAPAAPGAPAASGGFSGGALGAGPAPAADQAP--RRRSVTPAAKRHQCPF 150 160 170 180 190 150 160 170 180 190 200 pF1KB8 SGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPL :: :.: ::::::.: :.::::::: : : :: :::.:::::.::::::::::.: ::: CCDS58 PGCTKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSCPL 200 210 220 230 240 250 210 220 230 240 pF1KB8 CEKRFMRSDHLTKHARRHTEFHPSMIK-RSKKALANAL : :.: :::::::::::: .::.::. :... CCDS58 CPKQFSRSDHLTKHARRHPTYHPDMIEYRGRRRTPRIDPPLTSEVESSASGSGPGPAPSF 260 270 280 290 300 310 CCDS58 TTCL 320 >>CCDS47905.1 KLF10 gene_id:7071|Hs108|chr8 (469 aa) initn: 501 init1: 475 opt: 497 Z-score: 340.4 bits: 71.4 E(32554): 1.2e-12 Smith-Waterman score: 497; 47.8% identity (67.3% similar) in 159 aa overlap (75-225:284-440) 50 60 70 80 90 pF1KB8 KEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSL----ESPDED-MGSDSDV : : :.:: . . : : . CCDS47 GGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQP 260 270 280 290 300 310 100 110 120 130 140 150 pF1KB8 TTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKR---HKCPYSGCGKVYGK ...:.. : ::. . ::.: . :..: . . .: : : . ::::.: : CCDS47 VVQSSKPPVVSPNGTRLSPIAPAP--GFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFK 320 330 340 350 360 370 160 170 180 190 200 210 pF1KB8 SSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSD ::::::: :.::::.:: :.: : ..:.:::::.:: :::::::.: ::.:..:::::: CCDS47 SSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSD 380 390 400 410 420 430 220 230 240 pF1KB8 HLTKHARRHTEFHPSMIKRSKKALANAL ::::::::: CCDS47 HLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 440 450 460 >>CCDS6294.1 KLF10 gene_id:7071|Hs108|chr8 (480 aa) initn: 501 init1: 475 opt: 497 Z-score: 340.3 bits: 71.4 E(32554): 1.2e-12 Smith-Waterman score: 497; 47.8% identity (67.3% similar) in 159 aa overlap (75-225:295-451) 50 60 70 80 90 pF1KB8 KEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSL----ESPDED-MGSDSDV : : :.:: . . : : . CCDS62 GGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQP 270 280 290 300 310 320 100 110 120 130 140 150 pF1KB8 TTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKR---HKCPYSGCGKVYGK ...:.. : ::. . ::.: . :..: . . .: : : . ::::.: : CCDS62 VVQSSKPPVVSPNGTRLSPIAPAP--GFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFK 330 340 350 360 370 380 160 170 180 190 200 210 pF1KB8 SSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSD ::::::: :.::::.:: :.: : ..:.:::::.:: :::::::.: ::.:..:::::: CCDS62 SSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSD 390 400 410 420 430 440 220 230 240 pF1KB8 HLTKHARRHTEFHPSMIKRSKKALANAL ::::::::: CCDS62 HLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 450 460 470 480 >>CCDS5372.1 SP8 gene_id:221833|Hs108|chr7 (490 aa) initn: 576 init1: 438 opt: 484 Z-score: 331.8 bits: 69.9 E(32554): 3.7e-12 Smith-Waterman score: 484; 46.0% identity (65.6% similar) in 163 aa overlap (70-226:280-439) 40 50 60 70 80 90 pF1KB8 EREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSD--- .. ..:. :. :: :: :.. CCDS53 GYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPV-LPGSYPDSAPSPLAGAGGSMLS 250 260 270 280 290 300 100 110 120 130 140 150 pF1KB8 SDVTTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKR---HKCPYSGCGKV . .. :.:: : .. . .. : .. : :: .: :.: ::::: CCDS53 AGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAG--ASLRRKGLHSCHIPGCGKV 310 320 330 340 350 360 160 170 180 190 200 210 pF1KB8 YGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFM :::.:::::: : ::::::: :.: : :.:.::::: :: :::::::.: ::.:.:::: CCDS53 YGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFM 370 380 390 400 410 420 220 230 240 pF1KB8 RSDHLTKHARRHTEFHPSMIKRSKKALANAL :::::.::.. :. CCDS53 RSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHR 430 440 450 460 470 480 >>CCDS43555.1 SP8 gene_id:221833|Hs108|chr7 (508 aa) initn: 576 init1: 438 opt: 484 Z-score: 331.7 bits: 69.9 E(32554): 3.7e-12 Smith-Waterman score: 484; 46.0% identity (65.6% similar) in 163 aa overlap (70-226:298-457) 40 50 60 70 80 90 pF1KB8 EREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSD--- .. ..:. :. :: :: :.. CCDS43 GYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPV-LPGSYPDSAPSPLAGAGGSMLS 270 280 290 300 310 320 100 110 120 130 140 150 pF1KB8 SDVTTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKR---HKCPYSGCGKV . .. :.:: : .. . .. : .. : :: .: :.: ::::: CCDS43 AGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAG--ASLRRKGLHSCHIPGCGKV 330 340 350 360 370 380 160 170 180 190 200 210 pF1KB8 YGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFM :::.:::::: : ::::::: :.: : :.:.::::: :: :::::::.: ::.:.:::: CCDS43 YGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFM 390 400 410 420 430 440 220 230 240 pF1KB8 RSDHLTKHARRHTEFHPSMIKRSKKALANAL :::::.::.. :. CCDS43 RSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHR 450 460 470 480 490 500 >>CCDS46453.1 SP9 gene_id:100131390|Hs108|chr2 (484 aa) initn: 525 init1: 435 opt: 471 Z-score: 323.6 bits: 68.3 E(32554): 1.1e-11 Smith-Waterman score: 471; 44.8% identity (66.3% similar) in 172 aa overlap (60-225:247-414) 30 40 50 60 70 80 pF1KB8 APDAERLRLPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESP :.. .. :: . ..:. :: ::: . CCDS46 LGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPV-LPSY-SDSSAAV 220 230 240 250 260 270 90 100 110 120 130 140 pF1KB8 DEDMGS---DSDVTTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKR---H .: .. ... .:.: ..: .. . .. : .. : :: .: : CCDS46 AAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAG--ASLRRKGLH 280 290 300 310 320 330 150 160 170 180 190 200 pF1KB8 KCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQF .: ::::::::.:::::: : ::::::: :.: : :.:.::::: :: :::::::.: CCDS46 SCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRF 340 350 360 370 380 390 210 220 230 240 pF1KB8 RCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKKALANAL ::.:.:::::::::.:: . : CCDS46 ACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSA 400 410 420 430 440 450 >>CCDS44898.1 SP1 gene_id:6667|Hs108|chr12 (778 aa) initn: 559 init1: 437 opt: 473 Z-score: 322.3 bits: 68.8 E(32554): 1.2e-11 Smith-Waterman score: 473; 50.4% identity (68.6% similar) in 137 aa overlap (91-225:566-701) 70 80 90 100 110 pF1KB8 VTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSPE--ERQDPG . . .:. :. .::. .:. .: CCDS44 QVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENSPDAQPQAGRRTRRE 540 550 560 570 580 590 120 130 140 150 160 170 pF1KB8 SAPSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWP . : : ..: ...:.: : .::::::::.:::.:: : ::::::: ::: CCDS44 ACTCPYCKDSEG-RGSGDPGKKKQHICHIQGCGKVYGKTSHLRAHLRWHTGERPFMCTWS 600 610 620 630 640 650 180 190 200 210 220 230 pF1KB8 DCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKK : :.:.::::: :: :::::::.: :: : :::::::::.:: . : CCDS44 YCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTHQNKKGGPGVALSV 660 670 680 690 700 710 240 pF1KB8 ALANAL CCDS44 GTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGINVMQVADLQSINIS 720 730 740 750 760 770 244 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:27:17 2016 done: Fri Nov 4 16:27:17 2016 Total Scan time: 2.400 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]