FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8911, 250 aa 1>>>pF1KB8911 250 - 250 aa - 250 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5684+/-0.000342; mu= 7.0949+/- 0.022 mean_var=212.5662+/-44.577, 0's: 0 Z-trim(121.4): 197 B-trim: 32 in 1/55 Lambda= 0.087968 statistics sampled from 37642 (37876) to 37642 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.444), width: 16 Scan time: 7.720 The best scores are: opt bits E(85289) NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 1718 229.8 3.6e-60 NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 714 102.4 8.5e-22 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 592 86.9 4e-17 NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 475 72.2 1.4e-12 NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 432 66.7 6e-11 NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 427 66.1 9.4e-11 NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 416 64.8 2.8e-10 NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 368 58.6 1.7e-08 NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 346 55.8 1.1e-07 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 333 53.9 2.7e-07 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 321 52.5 9.4e-07 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 318 52.2 1.2e-06 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 52.7 1.3e-06 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 52.7 1.3e-06 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 52.7 1.3e-06 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 52.7 1.3e-06 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 52.7 1.3e-06 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 321 52.7 1.3e-06 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 321 52.7 1.3e-06 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 313 51.4 1.7e-06 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 310 51.1 2.2e-06 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 310 51.1 2.2e-06 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 310 51.1 2.2e-06 NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 309 51.0 2.8e-06 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 306 50.5 2.9e-06 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 296 49.3 8.1e-06 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 294 49.0 8.8e-06 NP_000513 (OMIM: 140000,142959,176305) homeobox pr ( 388) 291 48.9 1.6e-05 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 284 47.7 2.1e-05 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 286 48.1 2.2e-05 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 282 47.5 2.5e-05 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 282 47.5 2.5e-05 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 282 47.5 2.5e-05 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 275 46.2 2.8e-05 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 282 47.6 2.9e-05 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 276 46.8 4.7e-05 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 279 47.4 4.9e-05 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 275 46.6 5e-05 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 276 46.8 5.1e-05 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 276 47.0 6.4e-05 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 276 47.0 6.4e-05 NP_067016 (OMIM: 142988) homeobox protein Hox-D12 ( 270) 271 46.2 7.3e-05 NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 270 46.0 7.9e-05 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 269 46.0 9.3e-05 >>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo (250 aa) initn: 1718 init1: 1718 opt: 1718 Z-score: 1201.2 bits: 229.8 E(85289): 3.6e-60 Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250) 10 20 30 40 50 60 pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM 190 200 210 220 230 240 250 pF1KB8 KKMNKEQGKE :::::::::: NP_076 KKMNKEQGKE 250 >>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo (260 aa) initn: 769 init1: 485 opt: 714 Z-score: 512.3 bits: 102.4 E(85289): 8.5e-22 Smith-Waterman score: 778; 51.9% identity (68.7% similar) in 262 aa overlap (1-247:1-254) 10 20 30 40 50 pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFP-SGQY-ASSRQPGHAEHL-EFPSCSFQPKAP :: .: .:.:::::.:::..:: ..:: .: . :..: : . .:::::: :: NP_008 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP----GQGQ ::..::::. ..: ::::: :: :..::.:::::: . . : : . NP_008 VFSTSWAPVPSQSS----VVYHPY-GPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRH 70 80 90 100 110 120 130 140 150 160 pF1KB8 AAVKAEPLLG-----APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKE :.: . : .::: .. :.: . : :. . : . ::. :: NP_008 YALKPDAYPGRRADCGPGE--GRSYPDY-MYGSPGELRDRAPQTLPSPEADALAGSKHKE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 RP---DQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS . : .:: :::.::::.::::::::::::::::::::::::::::::.::::.:::. NP_008 EKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLT 180 190 200 210 220 230 230 240 250 pF1KB8 ERQVKIWFQNRRMKMKKMNKEQGKE :::::::::::::::::::::. NP_008 ERQVKIWFQNRRMKMKKMNKEKTDKEQS 240 250 260 >>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo (272 aa) initn: 704 init1: 485 opt: 592 Z-score: 428.4 bits: 86.9 E(85289): 4e-17 Smith-Waterman score: 761; 49.5% identity (69.5% similar) in 275 aa overlap (1-250:1-271) 10 20 30 40 50 pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSR--QPGH-----AEHLEFPSCSFQ :. .:.:..:::::.. . :: .. :.:: . :: . ::: .: :::: NP_689 MATTGALGNYYVDSFLL--GADAAD-ELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQ 10 20 30 40 50 60 70 80 90 100 pF1KB8 PKAPVFGASWAPLSPHASGSLPS-VYH-----PYIQPQGVPPA----ESRYLRTWLEPAP :: :::::: :. .....:. ::: ::..::. : : ..::.:.::::.: NP_689 SKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQA-PVAAAAPDGRYMRSWLEPTP 60 70 80 90 100 110 110 120 130 140 150 pF1KB8 RG---EAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSA-GREAVLSNQRPGYG--- . . :.. ..: ::: . :. : :: : : : ...:. : NP_689 GALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB8 -DNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRR .: :.. :: : .::.::::::::.:::::::::.:::::::::::::::::::: NP_689 ENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRR 180 190 200 210 220 230 220 230 240 250 pF1KB8 HEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE .::::::::.:::::::::::::::::.::...:. NP_689 YEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE 240 250 260 270 >>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo (352 aa) initn: 674 init1: 467 opt: 475 Z-score: 346.8 bits: 72.2 E(85289): 1.4e-12 Smith-Waterman score: 536; 39.9% identity (57.6% similar) in 278 aa overlap (54-247:70-347) 30 40 50 60 70 80 pF1KB8 PPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWA--PLSPHASGSLPSVYHPY :.. ::.:::. : .: :.... ..:::: NP_055 PPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPY 40 50 60 70 80 90 90 100 110 120 pF1KB8 IQPQGVPPAES---RYLRTWLEPAPR-----------GEAAPGQGQAAVKAEPLLG---- . : . . : ::.:.:.:: : : ..::.: . . : : NP_055 VPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYG 100 110 120 130 140 150 130 140 pF1KB8 -------APGELL--------------------------KQGT--PEYSLETSAGREAVL ::. .::. ::.: .. ..:. NP_055 IKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAA 160 170 180 190 200 210 150 160 170 pF1KB8 SN--QRPGYG-----------------DNKI--CEGSEDKER---PDQ-----TNPSANW .. :: : :. : : .:.... :.: .::.::: NP_055 ATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANW 220 230 240 250 260 270 180 190 200 210 220 230 pF1KB8 LHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMK .::::.::::::::::::::::::::::::::::::.::::.:::.:::::::::::::: NP_055 IHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMK 280 290 300 310 320 330 240 250 pF1KB8 MKKMNKEQGKE ::::.::. NP_055 MKKMSKEKCPKGD 340 350 >>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D (340 aa) initn: 478 init1: 401 opt: 432 Z-score: 317.5 bits: 66.7 E(85289): 6e-11 Smith-Waterman score: 436; 39.4% identity (64.2% similar) in 218 aa overlap (35-246:125-327) 10 20 30 40 50 60 pF1KB8 GTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQ-PKAPVFGASW :.. :.. ..: :: . :..:: : . NP_002 TQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSY-QRLVPESCPVENPEVPVPG--Y 100 110 120 130 140 150 70 80 90 100 110 120 pF1KB8 APLSP-HASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLL :: .:.:. . .:.: . :. ::: : : . : .. : . NP_002 FRLSQTYATGKTQEYNN---SPEGSSTV-------MLQLNPRGAAKPQLSAAQLQMEKKM 160 170 180 190 200 130 140 150 160 170 pF1KB8 GAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKIC----EGSEDKERPDQTNPSAN . : . : . : : .. : ..: .. .. . .:.::. . .:..: NP_002 NEP--VSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSN 210 220 230 240 250 180 190 200 210 220 230 pF1KB8 WLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRM :: :.:.:::::::::.:::::::::::::::::.:: :... .::..:::::::::::: NP_002 WLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRM 260 270 280 290 300 310 240 250 pF1KB8 KMKKMNKEQGKE :.:::..: NP_002 KLKKMSRENRIRELTANLTFS 320 330 340 >>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom (342 aa) initn: 429 init1: 404 opt: 427 Z-score: 314.0 bits: 66.1 E(85289): 9.4e-11 Smith-Waterman score: 451; 41.7% identity (65.4% similar) in 211 aa overlap (43-246:140-329) 20 30 40 50 60 70 pF1KB8 DSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASG :: : : :. .: ..: .:: :: NP_059 VCCMYSAEKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSA--LDKTPHCSG 110 120 130 140 150 160 80 90 100 110 120 pF1KB8 SLPSVYHPYIQPQGVPPA----ESRYL--RTWLEPAPRGEA-APGQGQAAVKAEPLLGAP . . :. : .. : :: : .. . .:.... .:. .. .:.: :..: NP_059 A-NDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNE--IKTEQSLAGP 170 180 190 200 210 220 130 140 150 160 170 180 pF1KB8 GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSS .:.: : . ..: ... : .:: : ::. : ..::: :.:. NP_059 -----KGSPSESEK----ERAKAADSSPDTSDN------EAKEEIKAENTTGNWLTAKSG 230 240 250 260 190 200 210 220 230 240 pF1KB8 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK :::::::::.:::::::::::::::::.:: :... .::..:::::::::::::.::::. NP_059 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR 270 280 290 300 310 320 250 pF1KB8 EQGKE : NP_059 ENRIRELTSNFNFT 330 340 >>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom (410 aa) initn: 447 init1: 390 opt: 416 Z-score: 305.6 bits: 64.8 E(85289): 2.8e-10 Smith-Waterman score: 416; 47.8% identity (68.6% similar) in 159 aa overlap (100-246:244-397) 70 80 90 100 110 120 pF1KB8 ASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP-----GQGQAAVKAEPLLGA .: :: : :...:: : . : . NP_061 FRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSP 220 230 240 250 260 270 130 140 150 160 170 pF1KB8 PGELL-------KQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSA : : .:: : .::..: :: :. .... .:. .. . .: NP_061 PPPTLACGSGGGSQGDEEAHASSSAAEE--LS---PAPSESSKASPEKDSLGNSKGENAA 280 290 300 310 320 180 190 200 210 220 230 pF1KB8 NWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRR ::: :.:.:::::::::.:::::::::::::::::.:: :..: ..:..::::::::::: NP_061 NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRR 330 340 350 360 370 380 240 250 pF1KB8 MKMKKMNKEQGKE ::.::::.: NP_061 MKLKKMNRENRIRELTANFNFS 390 400 410 >>NP_067015 (OMIM: 142986) homeobox protein Hox-D11 [Hom (338 aa) initn: 369 init1: 312 opt: 368 Z-score: 273.6 bits: 58.6 E(85289): 1.7e-08 Smith-Waterman score: 388; 38.2% identity (59.3% similar) in 204 aa overlap (48-247:137-328) 20 30 40 50 60 70 pF1KB8 HESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPH--ASGSLP :. :. :: .: : .: ::. NP_067 YAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYS 110 120 130 140 150 160 80 90 100 110 120 130 pF1KB8 SVYHPYIQPQGVPP-AESRYLRTWLEPAPRGEAAPGQGQ-AAVKAEPLLGAPGELLKQGT .: . : ::: :. . : : :: : . :: :..: :: : :. NP_067 AVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGG---GGGS 170 180 190 200 210 220 140 150 160 170 180 190 pF1KB8 PEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYT : ... : : . . : ::.. : :. :.. . . ::::::::: NP_067 P--CTKATPGSEPKGAAEGSG-GDGEGPPGEAGAEK------SSSAVAPQRSRKKRCPYT 230 240 250 260 270 200 210 220 230 240 250 pF1KB8 KYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE ::: :::.::.::.:.....: ...:.:::..::::::::::::: ::.:... NP_067 KYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTG 280 290 300 310 320 330 NP_067 NPLF >>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A (313 aa) initn: 370 init1: 300 opt: 346 Z-score: 259.0 bits: 55.8 E(85289): 1.1e-07 Smith-Waterman score: 357; 33.1% identity (61.3% similar) in 248 aa overlap (24-247:69-303) 10 20 30 40 pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKF-PSGQYA---SSRQPGHAEHLEFPS : .:. : :. : :... : . :. :: NP_005 SSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPS 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB8 CSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQPQGV-PPAESRYLRTWLEPAPRGEAA . : . :.. : : . : . .. : .. . .:: : : .....: .:.. :. NP_005 AAGVP-GDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFET-AYGTPENLAS 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB8 ---PGQGQAAVKAEPL---LGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICE ::. ..: :. : .: . :.: : :.: : : . NP_005 SDYPGD-KSAEKGPPAATATSAAAAAAATGAPATSSSDSGG----------GGGCRETAA 160 170 180 190 200 170 180 190 200 pF1KB8 GSEDKER---PDQTN-PSANWLHARS---------SRKKRCPYTKYQTLELEKEFLFNMY ..:.::: :.... : .. :... .::::::::::: :::.::.:..: NP_005 AAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVY 210 220 230 240 250 260 210 220 230 240 250 pF1KB8 LTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE .....: ...:.:::..::::::::::::: ::.:... NP_005 INKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL 270 280 290 300 310 >>NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [Homo (222 aa) initn: 328 init1: 284 opt: 333 Z-score: 251.8 bits: 53.9 E(85289): 2.7e-07 Smith-Waterman score: 333; 37.0% identity (57.8% similar) in 211 aa overlap (48-250:17-220) 20 30 40 50 60 70 pF1KB8 HESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLP-S :. ..: . .:: . : . :.: : NP_061 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLS 10 20 30 40 80 90 100 110 120 130 pF1KB8 VYHPYIQP----QGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQG . : : .:: : . . .:: . ::::.. . .: :: :: . .: NP_061 ITFPPPAPSNSLHGVDMAANPRAHP-DRPACSAAAAPGHAPGRDEAAPL--NPG-MYSQK 50 60 70 80 90 100 140 150 160 170 180 pF1KB8 TPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHAR---SSRKKR . . .:: : . ..... :. : . : : : . :: .....: NP_061 AARPALEERAKSSGEIKEEQAQTGQPA---GLSQPPAPPQIYPWMTKLHMSHETDGKRSR 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 CPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGK ::.:::::::::: :: :::: :: :.: : :.:::.:::::::::: :: .: ..: NP_061 TSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSK 160 170 180 190 200 210 250 pF1KB8 E : NP_061 EAL 220 250 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:27:55 2016 done: Fri Nov 4 16:27:56 2016 Total Scan time: 7.720 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]