FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8914, 255 aa 1>>>pF1KB8914 255 - 255 aa - 255 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4137+/-0.000378; mu= 2.3300+/- 0.024 mean_var=468.3695+/-95.252, 0's: 0 Z-trim(126.7): 129 B-trim: 999 in 1/56 Lambda= 0.059262 statistics sampled from 53029 (53197) to 53029 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.866), E-opt: 0.2 (0.624), width: 16 Scan time: 8.680 The best scores are: opt bits E(85289) NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 1819 168.4 1.2e-41 XP_005246571 (OMIM: 142981) PREDICTED: homeobox pr ( 146) 1072 104.1 1.4e-22 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 903 90.1 4.4e-18 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 903 90.1 4.4e-18 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 852 85.7 8.8e-17 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 744 76.6 6.1e-14 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 526 57.9 2.3e-08 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 499 55.4 1e-07 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 481 53.9 2.9e-07 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 481 53.9 2.9e-07 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 481 53.9 2.9e-07 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 481 54.0 3.4e-07 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 459 52.1 1.2e-06 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 445 50.8 2.5e-06 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 393 46.1 4.4e-05 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 396 46.6 4.4e-05 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 397 47.0 5.5e-05 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 393 46.4 5.5e-05 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 380 45.4 0.00013 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 376 44.9 0.00015 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 371 44.9 0.00029 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 371 44.9 0.00029 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 368 44.7 0.00035 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 368 44.7 0.00035 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 368 44.7 0.00035 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 368 44.7 0.00035 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 368 44.7 0.00035 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 368 44.7 0.00035 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 368 44.7 0.00035 NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 344 42.3 0.0011 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 347 42.8 0.0011 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 343 42.3 0.0012 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 338 41.8 0.0016 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 338 42.0 0.0018 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 338 42.0 0.0018 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 338 42.1 0.002 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 338 42.1 0.002 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 338 42.1 0.002 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 338 42.1 0.002 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 338 42.1 0.002 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 338 42.1 0.002 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 338 42.1 0.002 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 338 42.2 0.0022 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 338 42.3 0.0024 >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 1819 init1: 1819 opt: 1819 Z-score: 869.0 bits: 168.4 E(85289): 1.2e-41 Smith-Waterman score: 1819; 99.6% identity (99.6% similar) in 255 aa overlap (1-255:1-255) 10 20 30 40 50 60 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLT :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQH 190 200 210 220 230 240 250 pF1KB8 LQPMAKDHHTDLTTL ::::::::::::::: NP_055 LQPMAKDHHTDLTTL 250 >>XP_005246571 (OMIM: 142981) PREDICTED: homeobox protei (146 aa) initn: 1072 init1: 1072 opt: 1072 Z-score: 526.3 bits: 104.1 E(85289): 1.4e-22 Smith-Waterman score: 1072; 99.3% identity (99.3% similar) in 144 aa overlap (1-144:1-144) 10 20 30 40 50 60 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLT :: ::::::::::::::::::::: XP_005 PPSGTALKQPAVVYPWMKKVHVNSGI 130 140 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 828 init1: 597 opt: 903 Z-score: 445.6 bits: 90.1 E(85289): 4.4e-18 Smith-Waterman score: 903; 54.4% identity (73.5% similar) in 272 aa overlap (1-255:1-264) 10 20 30 40 50 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYG----GGAQG--ADFQPPGLYPR :.::::...:.:.:::::::::: :..:. :.. .::: .: : .. :: :: NP_705 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PDFGEQPFGGSG-PGPGSALPARGHGQEPGGPGGHYAAPGEP-C-PAPPAPPPA-PLPGA :.. :. .. .. :::.. :::: :. : :. .. : ::: . : : :. NP_705 PSYPERQYSCTSLQGPGNS---RGHG--PAQAGHHHPEKSQSLCEPAPLSGASASPSPAP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RAYSQSDPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELE : :: : .: ..: ::: .:::::::.::..:::::.:::::::::::::::::::: NP_705 PACSQPAPDHPS-SAASKQP-IVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELE 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 KEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSS------- ::::.::::::::::::::.:::::::::::::::::::::::.::::: ::. NP_705 KEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP 180 190 200 210 220 230 230 240 250 pF1KB8 SSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL :. :... ..: :: : ... :.: : NP_705 STLSAATPGTSEDHSQSATPPEQQRAEDITRL 240 250 260 >>NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 828 init1: 597 opt: 903 Z-score: 445.6 bits: 90.1 E(85289): 4.4e-18 Smith-Waterman score: 903; 54.4% identity (73.5% similar) in 272 aa overlap (1-255:1-264) 10 20 30 40 50 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYG----GGAQG--ADFQPPGLYPR :.::::...:.:.:::::::::: :..:. :.. .::: .: : .. :: :: NP_055 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PDFGEQPFGGSG-PGPGSALPARGHGQEPGGPGGHYAAPGEP-C-PAPPAPPPA-PLPGA :.. :. .. .. :::.. :::: :. : :. .. : ::: . : : :. NP_055 PSYPERQYSCTSLQGPGNS---RGHG--PAQAGHHHPEKSQSLCEPAPLSGASASPSPAP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RAYSQSDPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELE : :: : .: ..: ::: .:::::::.::..:::::.:::::::::::::::::::: NP_055 PACSQPAPDHPS-SAASKQP-IVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELE 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 KEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSS------- ::::.::::::::::::::.:::::::::::::::::::::::.::::: ::. NP_055 KEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP 180 190 200 210 220 230 230 240 250 pF1KB8 SSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL :. :... ..: :: : ... :.: : NP_055 STLSAATPGTSEDHSQSATPPEQQRAEDITRL 240 250 260 >>NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [Homo (251 aa) initn: 963 init1: 599 opt: 852 Z-score: 422.3 bits: 85.7 E(85289): 8.8e-17 Smith-Waterman score: 856; 57.7% identity (71.4% similar) in 248 aa overlap (1-229:1-237) 10 20 30 40 50 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYL-GEQGADYYGGGAQG-ADFQPP-GLYPRPDF :.:::...::.:::::::::::: :. :: .... ::.:: . ..::: :. : NP_076 MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEAGFGRRAAC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GEQPFGGS-GPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPA----PLPGAR- : ... ::: : : : :: : :::::: : :: : NP_076 TVQRYAACRDPGPPPPPPP----PPPPPP-----PPGLS-PRAPAPPPAGALLPEPGQRC 70 80 90 100 110 120 130 140 150 160 pF1KB8 -AYSQSDPKQP---------PPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAY : :.: : : : .: :.: ::::::.::::..:::::.::::::::::: NP_076 EAVSSSPPPPPCAQNPLHPSPSHSACKEP-VVYPWMRKVHVSTVNPNYAGGEPKRSRTAY 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 TRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGR :::::::::::::.:::::::::.::::.::::::::::::::::::::::::::::: : NP_076 TRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIR 170 180 190 200 210 220 230 240 250 pF1KB8 SSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL :.....:. NP_076 SGGAAGSAGGPPGRPNGGPRAL 230 240 250 >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 835 init1: 633 opt: 744 Z-score: 371.3 bits: 76.6 E(85289): 6.1e-14 Smith-Waterman score: 744; 53.2% identity (66.5% similar) in 248 aa overlap (4-243:71-306) 10 20 30 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQG .::.. .: .: : : NP_002 GYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAY 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB8 ADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGG---HYA : :::. :: :.: ::: ... ::. .: : .: .: : . . NP_002 PYGYRGGAS------PGRPPQP---EQP-PAQAKGPAHGLHA-SHVLQPQLPPPLQPRAV 110 120 130 140 100 110 120 130 140 pF1KB8 APGEP--CPAPPAPPPAPLPG-ARAYSQSDPKQPPPGTALKQPAVVYPWMKKVHVNSVNP :. : : : :: : .: : : : . : : :.: ::::::::.::..::: NP_002 PPAAPRRCEAAPATPGVPAGGSAPACPLLLADKSPLGLKGKEP-VVYPWMKKIHVSAVNP 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB8 NYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRM .:.:::::::::::::::::::::::::::::::::::::::::::::::.::::::::: NP_002 SYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRM 210 220 230 240 250 260 210 220 230 240 250 pF1KB8 KWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQ--HLQPMAKDHHTDLTTL :::::::::::: :::.:.:.:. . : .: ::.: NP_002 KWKKDHKLPNTKMRSSNSASASAGPPGKAQTQSPHLHPHPHPSTSTPVPSSI 270 280 290 300 310 320 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 436 init1: 408 opt: 526 Z-score: 271.3 bits: 57.9 E(85289): 2.3e-08 Smith-Waterman score: 526; 47.1% identity (66.2% similar) in 204 aa overlap (27-215:62-256) 10 20 30 40 50 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGE-QGADYYGGGAQGADFQP----PGL :..: . : :...:..: .: :. NP_061 EQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPRYSQPAT 40 50 60 70 80 90 60 70 80 90 100 pF1KB8 Y---PRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGG-------HYAAPGEPCPAPPA :.:: : .. .:.::: :... .. :. : .. : : NP_061 STHSPQPD--PLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGA 100 110 120 130 140 110 120 130 140 150 160 pF1KB8 PPPAPLPGARAYSQSDPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAY :: . .: .::.:. ::. :: . ::::.:.:.. . : : : ::.:::: NP_061 EEDAPASSEQASAQSEPSPAPPA----QPQI-YPWMRKLHIS--HDNIGGPEGKRARTAY 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB8 TRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGR :: :.:::::::::::::::::::::::.::::::::::::::::::::::.:: NP_061 TRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMA 210 220 230 240 250 260 230 240 250 pF1KB8 SSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL NP_061 AAGGAFRP 270 >>NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [Homo (222 aa) initn: 483 init1: 366 opt: 499 Z-score: 259.7 bits: 55.4 E(85289): 1e-07 Smith-Waterman score: 499; 44.9% identity (64.0% similar) in 225 aa overlap (3-215:1-216) 10 20 30 40 50 pF1KB8 MVMSSYMVNSKYVD-PKFPPCEEYLQGGYLGE---QGADY-YGGGAQGADFQPPGLYPRP ::::..:: : . :..: . :.: . :.. : ::: . : ::. : NP_061 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPA--PSN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DFGEQPFGGSGPGPGSALPARGHGQEPG-GPGGHYAAPGEP-CPAPPAPPPAPLPGARAY .. .. ..: :: . . :: .:: ::: .: . : :: :.. NP_061 SLHGVDMA-ANPRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSS 60 70 80 90 100 110 120 130 140 150 160 pF1KB8 SQSDPKQPPPG--TALKQPAV---VYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLE .. .: : ..:.:: . .:::: :.:.. . : : :::::.::: :.:: NP_061 GEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMS----HETDG--KRSRTSYTRYQTLE 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 LEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSS ::::::::::::::::::::..:::.:::::::::::::::::: :. NP_061 LEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL 170 180 190 200 210 220 230 240 250 pF1KB8 SSCSSSVAPSQHLQPMAKDHHTDLTTL >>XP_005257341 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 440 init1: 371 opt: 481 Z-score: 251.3 bits: 53.9 E(85289): 2.9e-07 Smith-Waterman score: 481; 44.1% identity (57.2% similar) in 222 aa overlap (3-215:1-207) 10 20 30 40 50 60 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ ::::.::: :: : ..::. :..: :: : :: : .: XP_005 MSSYFVNS-----TFPVTLASGQESFLGQL--PLYSSGY--AD--PLRHYPAP-YGPG 10 20 30 40 70 80 90 100 110 pF1KB8 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPG------EPCP---APPAPPPAPLPGAR : .: . .: : : : ..: . ::. : : :: : : XP_005 PGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKS 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 AYSQSDPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEK .: : . : . :::::... :: : . : .:.: .::: :.::::: XP_005 DCAQ-DKSVFGETEEQKCSTPVYPWMQRM--NSCNSSSFGPSGRRGRQTYTRYQTLELEK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 EFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSC :::.::::::::::::::.:::.:::::::::::::::::. :: XP_005 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA 170 180 190 200 210 220 240 250 pF1KB8 SSSVAPSQHLQPMAKDHHTDLTTL XP_005 E >>XP_005257340 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 440 init1: 371 opt: 481 Z-score: 251.3 bits: 53.9 E(85289): 2.9e-07 Smith-Waterman score: 481; 44.1% identity (57.2% similar) in 222 aa overlap (3-215:1-207) 10 20 30 40 50 60 pF1KB8 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ ::::.::: :: : ..::. :..: :: : :: : .: XP_005 MSSYFVNS-----TFPVTLASGQESFLGQL--PLYSSGY--AD--PLRHYPAP-YGPG 10 20 30 40 70 80 90 100 110 pF1KB8 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPG------EPCP---APPAPPPAPLPGAR : .: . .: : : : ..: . ::. : : :: : : XP_005 PGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKS 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 AYSQSDPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEK .: : . : . :::::... :: : . : .:.: .::: :.::::: XP_005 DCAQ-DKSVFGETEEQKCSTPVYPWMQRM--NSCNSSSFGPSGRRGRQTYTRYQTLELEK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 EFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSC :::.::::::::::::::.:::.:::::::::::::::::. :: XP_005 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA 170 180 190 200 210 220 240 250 pF1KB8 SSSVAPSQHLQPMAKDHHTDLTTL XP_005 E 255 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:28:37 2016 done: Fri Nov 4 16:28:38 2016 Total Scan time: 8.680 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]