FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8917, 260 aa 1>>>pF1KB8917 260 - 260 aa - 260 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2148+/-0.000347; mu= 8.0237+/- 0.022 mean_var=186.1210+/-38.059, 0's: 0 Z-trim(120.8): 201 B-trim: 362 in 2/54 Lambda= 0.094011 statistics sampled from 36246 (36527) to 36246 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.428), width: 16 Scan time: 5.820 The best scores are: opt bits E(85289) NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 1815 257.7 1.5e-68 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 714 108.4 1.3e-23 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 693 105.6 9.9e-23 NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 531 83.7 4.9e-16 NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 464 74.7 2.9e-13 NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 449 72.6 1.1e-12 NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 431 70.2 5.7e-12 NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 339 57.7 3.3e-08 NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 335 57.1 4.4e-08 NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 324 55.6 1.3e-07 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 322 55.2 1.3e-07 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 313 54.1 3.4e-07 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 309 53.4 4.3e-07 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 310 53.7 4.5e-07 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 307 53.1 4.9e-07 NP_005915 (OMIM: 600535) homeobox protein MOX-2 [H ( 304) 306 53.1 6.8e-07 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 304 52.8 7e-07 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 302 52.5 8e-07 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 301 52.4 9.3e-07 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 301 52.4 9.3e-07 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 301 52.4 1e-06 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 299 52.2 1.4e-06 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 294 51.4 1.7e-06 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 290 51.0 3.1e-06 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 282 49.4 3.2e-06 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 288 50.6 3.3e-06 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 286 50.5 5.1e-06 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 283 50.0 5.4e-06 NP_776272 (OMIM: 142975) homeobox protein Hox-C12 ( 282) 282 49.9 6.1e-06 NP_000513 (OMIM: 140000,142959,176305) homeobox pr ( 388) 283 50.1 6.9e-06 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 277 49.1 8.4e-06 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 277 49.1 8.4e-06 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 277 49.1 8.4e-06 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 277 49.2 1e-05 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 278 49.5 1.2e-05 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 278 49.5 1.2e-05 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 278 49.5 1.2e-05 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 278 49.5 1.2e-05 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 278 49.5 1.2e-05 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 278 49.5 1.2e-05 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 278 49.5 1.2e-05 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 274 48.9 1.5e-05 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 273 48.7 1.6e-05 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 267 47.5 1.7e-05 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 270 48.2 1.8e-05 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 270 48.2 1.8e-05 NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 271 48.4 1.9e-05 XP_011533180 (OMIM: 600297) PREDICTED: homeobox pr ( 204) 266 47.5 2.2e-05 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 267 47.7 2.2e-05 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 266 47.6 2.6e-05 >>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo (260 aa) initn: 1815 init1: 1815 opt: 1815 Z-score: 1351.7 bits: 257.7 E(85289): 1.5e-68 Smith-Waterman score: 1815; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF 190 200 210 220 230 240 250 260 pF1KB8 QNRRMKMKKMNKEKTDKEQS :::::::::::::::::::: NP_008 QNRRMKMKKMNKEKTDKEQS 250 260 >>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo (250 aa) initn: 769 init1: 485 opt: 714 Z-score: 544.9 bits: 108.4 E(85289): 1.3e-23 Smith-Waterman score: 778; 51.9% identity (68.7% similar) in 262 aa overlap (1-254:1-247) 10 20 30 40 50 60 pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA :: .: .:.:::::.:::..:: ..:: .: . :..: : . .:::::: :: NP_076 MSISGTLSSYYVDSIISHESEDAPPAKFP-SGQY-ASSRQPGHAEHL-EFPSCSFQPKAP 10 20 30 40 50 70 80 90 100 110 pF1KB8 VFSTSWAPVPSQSS----VVYHPY-GPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRH ::..::::. ..: ::::: :: :..::.:::::: . . : : . NP_076 VFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP----GQGQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 YALKPDAYPGRRADCGPGE--GRSYPDY-MYGSPGELRDRAPQTLPSPEADALAGSKHKE :.: . : .::: .. :.: . : :. . : . ::. :: NP_076 AAVKAEPLLG-----APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKE 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 EKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLT . : .:: :::.::::.::::::::::::::::::::::::::::::.::::.:::. NP_076 RP---DQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS 170 180 190 200 210 220 240 250 260 pF1KB8 ERQVKIWFQNRRMKMKKMNKEKTDKEQS :::::::::::::::::::::. NP_076 ERQVKIWFQNRRMKMKKMNKEQGKE 230 240 250 >>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo (272 aa) initn: 800 init1: 537 opt: 693 Z-score: 529.1 bits: 105.6 E(85289): 9.9e-23 Smith-Waterman score: 824; 51.3% identity (70.4% similar) in 277 aa overlap (1-258:1-272) 10 20 30 40 50 pF1KB8 MSATGPISNYYVDS-LISHDNEDLLA-SRF-PATGAHPAAARPSGLVPDCSDFPSCSFAP :..:: ..:::::: :.. : : :. .:. :.: ..: : .. . . :: ::: NP_689 MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPP--RQAATLAEHPDFSPCSFQS 10 20 30 40 50 60 70 80 90 100 pF1KB8 KPAVFSTSWAPVPSQSS-----VVYH-----PY-GPQPHLGA---DTRYMRTWLEPLSGA : .::..:: :: . .. .::: :: :: ..: : ::::.:::: :: NP_689 KATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 VSFPSFPAGGRHYALKPDAYPGRRADCGPGEGR--SYPDYMYGSPGELRDRAPQTLPSPE .:: ..:.. : :..::. .::.:: . . : :: ::: :.. :. : NP_689 LSFAGLPSS-RPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 ADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDR .: : .: .::.::.:::.::::::::::::::.::::::::::::::::::: NP_689 NNAENESGG--DKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDR 180 190 200 210 220 230 230 240 250 260 pF1KB8 RYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS ::::::.:::::::::::::::::::::.::... : NP_689 RYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE 240 250 260 270 >>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo (352 aa) initn: 827 init1: 515 opt: 531 Z-score: 408.9 bits: 83.7 E(85289): 4.9e-16 Smith-Waterman score: 703; 47.8% identity (59.5% similar) in 289 aa overlap (49-257:62-350) 20 30 40 50 60 70 pF1KB8 DNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQS----- .: ::::::. ::::.::. :::: NP_055 EVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAA 40 50 60 70 80 90 80 90 100 pF1KB8 -SVVYHPYGPQPHLGADT----RYMRTWLEPLSG-------------------AVSFPSF : .:::: : : :.:.. ::.:.:.::: : :: NP_055 MSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSG 100 110 120 130 140 150 110 120 130 140 pF1KB8 PAGGRHYALKPD--AYPG-------------------RRADCG---PGEGRSYPDYMYGS ::.::::..::. : :. .:..:. ..: : :.. .: NP_055 PANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNS 160 170 180 190 200 210 150 160 170 pF1KB8 --------------PGELRDRAPQTLPSPEADA-----LAGSKHKEE--------KADLD :: : : : : .: . : . ::: . .:: NP_055 FLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLD 220 230 240 250 260 270 180 190 200 210 220 230 pF1KB8 PSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKI :.::.::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_055 PNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKI 280 290 300 310 320 330 240 250 260 pF1KB8 WFQNRRMKMKKMNKEKTDKEQS ::::::::::::.::: : NP_055 WFQNRRMKMKKMSKEKCPKGD 340 350 >>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom (410 aa) initn: 470 init1: 392 opt: 464 Z-score: 359.0 bits: 74.7 E(85289): 2.9e-13 Smith-Waterman score: 472; 40.3% identity (58.8% similar) in 243 aa overlap (25-258:175-402) 10 20 30 40 50 pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPA--AARPSGLVPDCSDFPS :.. : ..: : : : : :: . . NP_061 PQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGT 150 160 170 180 190 200 60 70 80 90 100 110 pF1KB8 CSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAG : .: :. : : : ... : .::: . : : :.. .: NP_061 SSGVPVPGYFRLSQAYGTAKG--YGSGGGGAQQLGAGPFPAQP---PGRGFDLPPALASG 210 220 230 240 250 120 130 140 150 160 pF1KB8 GRHYALKP---DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAP----QTLPSPEADAL . : : :. : :: : : . . ..: . .. .: .. ::: :.: NP_061 SADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSL 260 270 280 290 300 310 170 180 190 200 210 220 pF1KB8 AGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEV ..:: :.: :::. :.: :::::::::.:::::::::::::::::.:: :. NP_061 GNSKG--ENA--------ANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEI 320 330 340 350 360 230 240 250 260 pF1KB8 ARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS .: ..::.:::::::::::::.::::.:. .: NP_061 SRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS 370 380 390 400 410 >>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom (342 aa) initn: 439 init1: 418 opt: 449 Z-score: 349.0 bits: 72.6 E(85289): 1.1e-12 Smith-Waterman score: 470; 35.9% identity (60.2% similar) in 259 aa overlap (6-258:95-334) 10 20 30 pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHP :.:. ....: . : . . : NP_059 ALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGP 70 80 90 100 110 120 40 50 60 70 80 90 pF1KB8 AAARPSGLVPD-C---SDFPSCSFA-PKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADT :: : .:. : . : :. .:. . . .: : .. :. . :. . NP_059 EAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRA 130 140 150 160 170 180 100 110 120 130 140 pF1KB8 RYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGEL- ..... :.: :::: : . . .:. ... :: :::.: NP_059 EHLES--PQLGGKVSFPETPKSDSQTP-SPNEIKTEQSLAGPK----------GSPSESE 190 200 210 220 230 150 160 170 180 190 200 pF1KB8 RDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEK ..:: . ::. .. .: : .. : ..::. :.: :::::::::.::::::: NP_059 KERAKAADSSPD------TSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEK 240 250 260 270 280 210 220 230 240 250 260 pF1KB8 EFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS ::::::::::.:: :.....:::.:::::::::::::.::::.:. .: NP_059 EFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT 290 300 310 320 330 340 >>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D (340 aa) initn: 485 init1: 411 opt: 431 Z-score: 335.8 bits: 70.2 E(85289): 5.7e-12 Smith-Waterman score: 435; 39.4% identity (66.2% similar) in 216 aa overlap (43-258:134-332) 20 30 40 50 60 70 pF1KB8 DSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQ :::. . .: :. : : . . .. NP_002 TTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVEN-PEVPVPGYFRLSQTYATGK 110 120 130 140 150 160 80 90 100 110 120 130 pF1KB8 SSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGP . . :. .:. :..: ... :.: ::.. :.. :. .. : . . . NP_002 T----QEYNNSPE-GSSTVMLQ--LNP-RGAAK-PQLSAAQLQMEKKMNEPVSGQEPTKV 170 180 190 200 210 140 150 160 170 180 190 pF1KB8 GEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARST .. .: :. : : : : .. :::. ..:: : .. ..:..::. :.: NP_002 SQVES-PEAKGGLPEERSCLAEVSVSSPEV------QEKESKEEIKSDTPTSNWLTAKSG 220 230 240 250 260 200 210 220 230 240 250 pF1KB8 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNK :::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.:::.. NP_002 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSR 270 280 290 300 310 320 260 pF1KB8 EKTDKEQS :. .: NP_002 ENRIRELTANLTFS 330 340 >>NP_067015 (OMIM: 142986) homeobox protein Hox-D11 [Hom (338 aa) initn: 362 init1: 312 opt: 339 Z-score: 268.4 bits: 57.7 E(85289): 3.3e-08 Smith-Waterman score: 357; 34.5% identity (57.4% similar) in 235 aa overlap (30-254:116-328) 10 20 30 40 50 pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSF-APK :..: :: :.: . :. : ::. NP_067 GGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPE 90 100 110 120 130 140 60 70 80 90 100 110 pF1KB8 PAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYM----RTWLEPLSGAVSF----PSFP : . :: : :.:: :: . .. :. . : .: .: :. : NP_067 P----VCAAPGP--------PHGPA---GAASNFYSAVGRNGILP-QGFDQFYEAAPGPP 150 160 170 180 120 130 140 150 160 170 pF1KB8 AGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKH .: . : : : .. :. :. ::: .: . :. :.. .:. . NP_067 FAGPQPP-PPPAPPQPEGAADKGDPRTGAGGGGGSP--CTKATPGSEPKGAAEGSGGDGE 190 200 210 220 230 240 180 190 200 210 220 pF1KB8 KEE-KADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVL .: . :. . . . .::::::::::: :::.::.::.:.....: ...:.: NP_067 GPPGEAGAEKSSSA---VAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRML 250 260 270 280 290 300 230 240 250 260 pF1KB8 NLTERQVKIWFQNRRMKMKKMNKEKTDKEQS :::.::::::::::::: ::.:... NP_067 NLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF 310 320 330 >>NP_055027 (OMIM: 605559) homeobox protein Hox-C11 [Hom (304 aa) initn: 345 init1: 304 opt: 335 Z-score: 266.1 bits: 57.1 E(85289): 4.4e-08 Smith-Waterman score: 337; 31.4% identity (55.8% similar) in 226 aa overlap (40-254:79-294) 10 20 30 40 50 60 pF1KB8 YYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAP- ::: ... :: : . : NP_055 SFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPS 50 60 70 80 90 100 70 80 90 100 110 pF1KB8 ------VPSQSSVVYHPYGPQPHL---GADTRYMRTWLEPLSGAVSFPSFPAGGRHYALK . ...: : . :: : . .. . : . : . :: NP_055 TVTEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGD---- 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB8 PDAYPGRRADC-GPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLD : : : : : ::... :. .: : .: . : .. .:. . ... . NP_055 PPAEP----PCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKE 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB8 PSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKI :.. .: .: ::::::::.:.: :::.::.::.:.....: ...:.::::.::::: NP_055 PAKGAAP--NAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKI 230 240 250 260 270 240 250 260 pF1KB8 WFQNRRMKMKKMNKEKTDKEQS :::::::: ::..... NP_055 WFQNRRMKEKKLSRDRLQYFSGNPLL 280 290 300 >>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A (313 aa) initn: 355 init1: 310 opt: 324 Z-score: 257.8 bits: 55.6 E(85289): 1.3e-07 Smith-Waterman score: 350; 34.8% identity (54.0% similar) in 250 aa overlap (29-254:69-303) 10 20 30 40 50 pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAA-----RPSGLVP-DCSDFPS ::: :: . :: :: . :: NP_005 SSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPS 40 50 60 70 80 90 60 70 80 90 100 pF1KB8 CSFAPKPAVFSTSWA----PVPSQSSVVYHPYGPQPHLGA--DTRYMRTWLEPLSGAVS- . .: .. ..: :.:. :: : : . : : . .. : . : : NP_005 AAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSD 100 110 120 130 140 150 110 120 130 140 150 pF1KB8 FPS-------FPAGGRHYALKPDAYPGRRA----DCGPGEGRSYPDYMYGSPGELRDRAP .:. ::. : : : : : : : : . .. . : : : NP_005 YPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCR--ETAAAAEEKERRRRP 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB8 QTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFN .. :::.. : : :.:: . . . :::::::::::: :::.::.:. NP_005 ESSSSPESS----SGHTEDKAGGSSG---------QRTRKKRCPYTKYQIRELEREFFFS 220 230 240 250 260 220 230 240 250 260 pF1KB8 MYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS .:.....: ...:.::::.::::::::::::: ::.:... NP_005 VYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL 270 280 290 300 310 260 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:29:15 2016 done: Fri Nov 4 16:29:16 2016 Total Scan time: 5.820 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]