FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8919, 264 aa 1>>>pF1KB8919 264 - 264 aa - 264 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9281+/-0.000326; mu= 2.7929+/- 0.021 mean_var=309.7680+/-61.929, 0's: 0 Z-trim(125.7): 184 B-trim: 0 in 0/62 Lambda= 0.072871 statistics sampled from 49834 (50067) to 49834 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.853), E-opt: 0.2 (0.587), width: 16 Scan time: 8.020 The best scores are: opt bits E(85289) NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 1873 209.1 6.9e-54 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 1873 209.1 6.9e-54 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 925 109.4 6.7e-24 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 909 107.7 2.2e-23 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 705 86.4 7.2e-17 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 529 67.8 2.4e-11 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 497 64.4 2.5e-10 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 474 61.9 1.2e-09 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 474 61.9 1.2e-09 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 474 61.9 1.2e-09 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 474 62.0 1.4e-09 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 458 60.2 3.7e-09 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 422 56.5 5.3e-08 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 407 54.9 1.6e-07 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 400 54.1 2.6e-07 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 394 53.3 3.1e-07 XP_005246571 (OMIM: 142981) PREDICTED: homeobox pr ( 146) 382 52.0 7.2e-07 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 388 53.1 8.3e-07 NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 384 52.5 9.1e-07 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 376 51.6 1.4e-06 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 377 51.8 1.6e-06 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 364 50.7 5.5e-06 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 364 50.7 5.5e-06 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 364 50.7 5.5e-06 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 364 50.7 5.5e-06 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 364 50.7 5.5e-06 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 364 50.7 5.5e-06 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 364 50.7 5.5e-06 NP_005513 (OMIM: 142955,601536) homeobox protein H ( 335) 338 47.8 3e-05 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 340 48.2 3.1e-05 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 334 47.4 3.9e-05 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 332 47.1 4.4e-05 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 332 47.2 4.9e-05 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 332 47.2 4.9e-05 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 330 46.9 5.1e-05 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 333 47.4 5.2e-05 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 333 47.4 5.2e-05 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 333 47.4 5.2e-05 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 333 47.4 5.2e-05 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 333 47.4 5.2e-05 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 333 47.4 5.2e-05 NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 331 47.1 5.3e-05 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 332 47.4 6e-05 XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 333 47.6 6.2e-05 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 1873 init1: 1873 opt: 1873 Z-score: 1088.5 bits: 209.1 E(85289): 6.9e-54 Smith-Waterman score: 1873; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264) 10 20 30 40 50 60 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 SYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP 190 200 210 220 230 240 250 260 pF1KB8 GTSEDHSQSATPPEQQRAEDITRL :::::::::::::::::::::::: NP_705 GTSEDHSQSATPPEQQRAEDITRL 250 260 >>NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 1873 init1: 1873 opt: 1873 Z-score: 1088.5 bits: 209.1 E(85289): 6.9e-54 Smith-Waterman score: 1873; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264) 10 20 30 40 50 60 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP 190 200 210 220 230 240 250 260 pF1KB8 GTSEDHSQSATPPEQQRAEDITRL :::::::::::::::::::::::: NP_055 GTSEDHSQSATPPEQQRAEDITRL 250 260 >>NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [Homo (251 aa) initn: 1092 init1: 704 opt: 925 Z-score: 550.1 bits: 109.4 E(85289): 6.7e-24 Smith-Waterman score: 953; 59.9% identity (71.8% similar) in 252 aa overlap (1-231:1-237) 10 20 30 40 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIP-EHSPEYY--GRTRESGFQHHH-------- : :::.:..:::.::::::::::::..:.: .::: :: :. :::.:: . NP_076 MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEAGFGRRAAC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 --------QELYPPPPPRPSYPERQYSCTSLQGPGNS-RGHGPAQAGHHHPEKSQSLCEP .. ::::: : : :: : :. .: :: :: .: :: NP_076 TVQRYAACRDPGPPPPPPPPPPPPP-------PPGLSPRAPAPPPAGALLPEPGQR-CE- 70 80 90 100 110 110 120 130 140 150 pF1KB8 APLSGASASPSPAPPACSQ-PAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRS ..: :: :: :.: : :: .: :.:.:::::.:.::::::::: ::::::: NP_076 ------AVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRS 120 130 140 150 160 160 170 180 190 200 210 pF1KB8 RTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPN :::::::::::::::::::::::::::.::::.:::::::::::::::::::::::.::: NP_076 RTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPN 170 180 190 200 210 220 220 230 240 250 260 pF1KB8 TKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL ::.::. ::.: NP_076 TKIRSGGAAGSAGGPPGRPNGGPRAL 230 240 250 >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 828 init1: 597 opt: 909 Z-score: 540.9 bits: 107.7 E(85289): 2.2e-23 Smith-Waterman score: 909; 55.1% identity (73.5% similar) in 272 aa overlap (1-264:1-255) 10 20 30 40 50 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR :.::::...:.:.:::::::::: :..:. :.. .::: .: : .. :: :: NP_055 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYG----GGAQG--ADFQPPGLYPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PSYPERQYSCTSLQGPGNS---RGHG--PAQAGHHHPEKSQSLCEPAPLSGASASPSPAP :.. :. .. : :::.. :::: :. : :. .. : ::: . : : :. NP_055 PDFGEQPFG-GSGPGPGSALPARGHGQEPGGPGGHYAAPGEP-C-PAPPAPPPA-PLPGA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 PACSQPAPDHP-SSAASKQP-IVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELE : :: : .: :..: ::: .:::::::.::..:::::.:::::::::::::::::::: NP_055 RAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 KEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP ::::.::::::::::::::.:::::::::::::::::::::::.::::: ::. NP_055 KEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSS------- 180 190 200 210 220 240 250 260 pF1KB8 STLSAATPGTSEDHSQSATPPEQQRAEDITRL :. :... ..: :: : ... :.: : NP_055 SSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL 230 240 250 >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 820 init1: 659 opt: 705 Z-score: 423.9 bits: 86.4 E(85289): 7.2e-17 Smith-Waterman score: 705; 48.6% identity (62.5% similar) in 253 aa overlap (10-252:71-306) 10 20 30 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGR ..: :. : . : :. NP_002 GYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAA--DT 50 60 70 80 90 40 50 60 70 80 90 pF1KB8 TRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGP--GNSRGH------GPAQAGHHHP . :.. . : ::.: : : .:: : .: : . : NP_002 AYPYGYRGGAS---PGRPPQPEQPPAQA-----KGPAHGLHASHVLQPQLPPPLQPRAVP 100 110 120 130 140 150 100 110 120 130 140 pF1KB8 EKSQSLCEPAPLS-GASASPSPAPPACSQPAPDH-PSSAASKQPIVYPWMKKIHVSTVNP . :: :: . :. :. : ::: :. : . .:.:.:::::::::::.::: NP_002 PAAPRRCEAAPATPGVPAGGS--APACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNP 160 170 180 190 200 150 160 170 180 190 200 pF1KB8 NYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRM .::::::::::::::::::::::::::.::::::::::::::.:::::::.::::::::: NP_002 SYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRM 210 220 230 240 250 260 210 220 230 240 250 260 pF1KB8 KWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL ::::::.:::::.::. :.: ::. :: .. .: : NP_002 KWKKDHKLPNTKMRSSNSASA-----SAGPPGKAQTQSPHLHPHPHPSTSTPVPSSI 270 280 290 300 310 320 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 586 init1: 382 opt: 529 Z-score: 324.7 bits: 67.8 E(85289): 2.4e-11 Smith-Waterman score: 529; 49.2% identity (64.9% similar) in 185 aa overlap (54-231:96-267) 30 40 50 60 70 80 pF1KB8 SQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQ-GPGNSRGHG : : : : :... .::.. :: NP_061 SGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLP--------CSAVAPSPGSDSHHG 70 80 90 100 110 90 100 110 120 130 pF1KB8 -----PAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP-APDHPSSAASKQPIVY ..: : . .. ::.. :: . : : ..:: : :: .: NP_061 GKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIY 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB8 PWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLS :::.:.:.: . : .: : ::.:::::: :.::::::::.::::::::::::::.:::: NP_061 PWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB8 ERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQ ::::::::::::::::::..: : : ::.: NP_061 ERQIKIWFQNRRMKWKKDNKL---KSMSMAAAGGAFRP 240 250 260 270 260 pF1KB8 RAEDITRL >>NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [Homo (269 aa) initn: 452 init1: 384 opt: 497 Z-score: 306.6 bits: 64.4 E(85289): 2.5e-10 Smith-Waterman score: 520; 46.2% identity (67.2% similar) in 195 aa overlap (53-228:76-266) 30 40 50 60 70 pF1KB8 YSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGP------- .: : .: . . :: ::..: NP_002 GYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSC-SLSSPESLPCTN 50 60 70 80 90 100 80 90 100 110 120 pF1KB8 GNSRGHGP-AQAGHHHPEKSQSLCEPAPLSGASASPSPAPPAC---------SQPAPDHP :.:.: : :.. . ...: . . .. :::: : : .:: : NP_002 GDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMAT 110 120 130 140 150 160 130 140 150 160 170 180 pF1KB8 SSAA--SKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTR :.:: .. : ..:::.:.:.: ...: . ::.:::::: :.::::::::.:::::: NP_002 STAAPEGQTPQIFPWMRKLHIS---HDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTR 170 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 RRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTS ::::::::.::::::::::::::::::::::..: . .. .: : NP_002 RRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP 230 240 250 260 250 260 pF1KB8 EDHSQSATPPEQQRAEDITRL >>NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [Homo (224 aa) initn: 388 init1: 356 opt: 474 Z-score: 294.4 bits: 61.9 E(85289): 1.2e-09 Smith-Waterman score: 474; 41.1% identity (61.5% similar) in 231 aa overlap (8-225:1-215) 10 20 30 40 50 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR :.: ... :: .:.:.. . : : ::. .. :: : : NP_061 MSSYFVNSTFPVTLASGQESFLGQL-PLY-----SSGYADPLRH-YPAPYGPG 10 20 30 40 60 70 80 90 100 110 pF1KB8 PSYPERQYSCTSLQGP-GNSRG------HGPAQAGHHHPEKSQSLCEPAPLSGASASPS- :. .. .. .: : :.. : .::: : ... : : : ::::. .: NP_061 PGQ-DKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKE---SACA---LSGADEQPPF 50 60 70 80 90 120 130 140 150 160 pF1KB8 -PAP--PACSQPAPDHPSSAASK-QPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQ : : :.: . .: . :::::.... . : . : .:.: .::: : NP_061 HPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMN--SCNSSSFGPSGRRGRQTYTRYQ 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB8 VLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPP .:::::::::::::::::::::::.:::.:::::::::::::::::. .: ... :: NP_061 TLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEE 160 170 180 190 200 210 230 240 250 260 pF1KB8 AGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL NP_061 EEEKQAE 220 >>XP_005257340 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 388 init1: 356 opt: 474 Z-score: 294.4 bits: 61.9 E(85289): 1.2e-09 Smith-Waterman score: 474; 41.1% identity (61.5% similar) in 231 aa overlap (8-225:1-215) 10 20 30 40 50 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR :.: ... :: .:.:.. . : : ::. .. :: : : XP_005 MSSYFVNSTFPVTLASGQESFLGQL-PLY-----SSGYADPLRH-YPAPYGPG 10 20 30 40 60 70 80 90 100 110 pF1KB8 PSYPERQYSCTSLQGP-GNSRG------HGPAQAGHHHPEKSQSLCEPAPLSGASASPS- :. .. .. .: : :.. : .::: : ... : : : ::::. .: XP_005 PGQ-DKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKE---SACA---LSGADEQPPF 50 60 70 80 90 120 130 140 150 160 pF1KB8 -PAP--PACSQPAPDHPSSAASK-QPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQ : : :.: . .: . :::::.... . : . : .:.: .::: : XP_005 HPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMN--SCNSSSFGPSGRRGRQTYTRYQ 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB8 VLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPP .:::::::::::::::::::::::.:::.:::::::::::::::::. .: ... :: XP_005 TLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEE 160 170 180 190 200 210 230 240 250 260 pF1KB8 AGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL XP_005 EEEKQAE 220 >>XP_005257341 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 388 init1: 356 opt: 474 Z-score: 294.4 bits: 61.9 E(85289): 1.2e-09 Smith-Waterman score: 474; 41.1% identity (61.5% similar) in 231 aa overlap (8-225:1-215) 10 20 30 40 50 pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR :.: ... :: .:.:.. . : : ::. .. :: : : XP_005 MSSYFVNSTFPVTLASGQESFLGQL-PLY-----SSGYADPLRH-YPAPYGPG 10 20 30 40 60 70 80 90 100 110 pF1KB8 PSYPERQYSCTSLQGP-GNSRG------HGPAQAGHHHPEKSQSLCEPAPLSGASASPS- :. .. .. .: : :.. : .::: : ... : : : ::::. .: XP_005 PGQ-DKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKE---SACA---LSGADEQPPF 50 60 70 80 90 120 130 140 150 160 pF1KB8 -PAP--PACSQPAPDHPSSAASK-QPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQ : : :.: . .: . :::::.... . : . : .:.: .::: : XP_005 HPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMN--SCNSSSFGPSGRRGRQTYTRYQ 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB8 VLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPP .:::::::::::::::::::::::.:::.:::::::::::::::::. .: ... :: XP_005 TLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEE 160 170 180 190 200 210 230 240 250 260 pF1KB8 AGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL XP_005 EEEKQAE 220 264 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:30:00 2016 done: Fri Nov 4 16:30:01 2016 Total Scan time: 8.020 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]