Result of FASTA (omim) for pF1KB8932
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8932, 283 aa
  1>>>pF1KB8932 283 - 283 aa - 283 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8534+/-0.000332; mu= -2.2816+/- 0.021
 mean_var=317.4752+/-64.608, 0's: 0 Z-trim(126.0): 198  B-trim: 888 in 2/60
 Lambda= 0.071981
 statistics sampled from 50654 (50914) to 50654 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.85), E-opt: 0.2 (0.597), width:  16
 Scan time:  8.220

The best scores are:                                      opt bits E(85289)
NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 2029 223.0   5e-58
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  463 60.6 6.1e-09
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  463 60.6 6.1e-09
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  463 60.6 6.1e-09
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  463 60.6 6.1e-09
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  463 60.6 6.1e-09
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443)  463 60.6 6.1e-09
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443)  463 60.6 6.1e-09
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320)  394 53.3   7e-07
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356)  393 53.2 8.1e-07
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432)  393 53.3 9.3e-07
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432)  393 53.3 9.3e-07
NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251)  387 52.5 9.7e-07
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255)  380 51.7 1.6e-06
NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264)  377 51.4 2.1e-06
NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264)  377 51.4 2.1e-06
NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299)  367 50.5 4.7e-06
XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430)  370 50.9 4.9e-06
XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358)  367 50.5 5.3e-06
NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358)  367 50.5 5.3e-06
NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431)  367 50.6   6e-06
XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431)  367 50.6   6e-06
XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431)  367 50.6   6e-06
XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431)  367 50.6   6e-06
XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431)  367 50.6   6e-06
XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431)  367 50.6   6e-06
XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488)  367 50.7 6.6e-06
XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578)  367 50.7 7.4e-06
NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264)  355 49.2   1e-05
NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222)  317 45.1 0.00014
XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247)  317 45.2 0.00015
NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290)  318 45.4 0.00015
NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401)  320 45.7 0.00017
NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289)  315 45.0 0.00019
NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265)  312 44.7 0.00022
NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270)  311 44.6 0.00024
NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224)  309 44.3 0.00025


>>NP_000200 (OMIM: 125853,260370,600733,606176,606392) p  (283 aa)
 initn: 2029 init1: 2029 opt: 2029  Z-score: 1162.8  bits: 223.0 E(85289): 5e-58
Smith-Waterman score: 2029; 100.0% identity (100.0% similar) in 283 aa overlap (1-283:1-283)

               10        20        30        40        50        60
pF1KB8 MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 WMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 VMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPP
              190       200       210       220       230       240

              250       260       270       280   
pF1KB8 PPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
       :::::::::::::::::::::::::::::::::::::::::::
NP_000 PPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
              250       260       270       280   

>>XP_005249788 (OMIM: 142954) PREDICTED: homeobox protei  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
XP_005 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_005 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
XP_005 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
XP_005 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

XP_005 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>XP_005249789 (OMIM: 142954) PREDICTED: homeobox protei  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
XP_005 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_005 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
XP_005 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
XP_005 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

XP_005 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>XP_006715778 (OMIM: 142954) PREDICTED: homeobox protei  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
XP_006 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
XP_006 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
XP_006 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_006 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
XP_006 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
XP_006 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

XP_006 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>XP_011513645 (OMIM: 142954) PREDICTED: homeobox protei  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
XP_011 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
XP_011 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
XP_011 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_011 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
XP_011 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
XP_011 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

XP_011 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>XP_005249787 (OMIM: 142954) PREDICTED: homeobox protei  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
XP_005 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_005 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
XP_005 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
XP_005 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

XP_005 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>NP_705895 (OMIM: 142954) homeobox protein Hox-A3 isofo  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
NP_705 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
NP_705 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
NP_705 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
NP_705 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
NP_705 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
NP_705 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

NP_705 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>NP_109377 (OMIM: 142954) homeobox protein Hox-A3 isofo  (443 aa)
 initn: 453 init1: 310 opt: 463  Z-score: 281.5  bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)

                                        10               20        
pF1KB8                          MNGEEQYYAAT-------QLYKDPCAFQR----GP
                                 :...: : :.       . ..  :..:     : 
NP_109 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
               10        20        30        40        50        60

           30        40               50        60        70       
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
        :.      :::     ::  ::    :: :: :   .:    .::. .:   :: :  :
NP_109 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
               70        80        90        100       110         

        80        90         100        110       120       130    
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
       :.       : . : :   :.  : : ..:.  .:. :. ..  ::::: .. .. .   
NP_109 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
        120            130       140       150       160       170 

                 140        150       160       170       180      
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
           :.  .:  .   . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
NP_109 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
             180       190       200       210       220       230 

        190       200       210       220           230            
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
       ::.:::::::::::.::.. : .:  :. :: . ..    :     ..: . :. ..:  
NP_109 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
             240       250        260       270       280       290

     240       250       260       270       280                   
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR                
       :  ::  . :: .  .     :::.   .  :: . :  ::.                  
NP_109 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
              300            310       320       330       340     

NP_109 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
         350       360       370       380       390       400     

>>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo  (320 aa)
 initn: 383 init1: 290 opt: 394  Z-score: 244.5  bits: 53.3 E(85289): 7e-07
Smith-Waterman score: 415; 36.8% identity (57.7% similar) in 239 aa overlap (17-249:101-315)

                             10        20        30        40      
pF1KB8               MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPP
                                     : ... : .:   . ::    . .:::   
NP_002 ASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASP---GRPP----QPEQPPAQA
               80        90       100       110              120   

         50          60        70        80        90       100    
pF1KB8 PHPFPG--ALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGA
         :  :  :  .:.   :: ..:  ::: :  :   .     :.  :    :: :.   :
NP_002 KGPAHGLHASHVLQPQLPPPLQPRAVPPAA--PRRCEAAPATPGVPAGGSAPACPL-LLA
           130       140       150         160       170        180

          110       120       130       140       150       160    
pF1KB8 EPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKE
       . . :   ..  . .::::. .. : . .. ::    ::   ::.:::::: :.::::::
NP_002 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGG----EP---KRSRTAYTRQQVLELEKE
              190       200       210              220       230   

          170       180       190       200           210       220
pF1KB8 FLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEED----KKRGGGTAVGGGGV
       : ::.:..: ::.:.:  : :.::..:::::::::::::..     : :....: ...: 
NP_002 FHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAG-
           240       250       260       270       280       290   

              230       240       250       260       270       280
pF1KB8 AEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQ
         :     . : .    : : : :. ..:                               
NP_002 --PPGKAQTQSPH----LHPHPHPSTSTPVPSSI                          
              300           310       320                          

>>NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [Homo  (356 aa)
 initn: 380 init1: 281 opt: 393  Z-score: 243.4  bits: 53.2 E(85289): 8.1e-07
Smith-Waterman score: 406; 34.8% identity (51.5% similar) in 264 aa overlap (45-282:44-302)

           20        30        40        50        60        70    
pF1KB8 KDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLA
                                     ::: ::  .. .:. :.     :       
NP_002 SQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRAE
            20        30        40        50        60        70   

           80        90        100       110        120       130  
pF1KB8 DDPAVAHLHHHLPAQLALPH-PPAGPFPEGAEPGVLEEPNRVQL-PFPWMKSTKAHAWKG
       : ::.       :    ::  :::  ::   :    ..:..    : :  ... : .  .
NP_002 DGPALPP-----PPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGS
            80             90       100       110       120        

             140       150       160       170       180       190 
pF1KB8 QWAG-GAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIK
          : :   :     .: ::::: .::::::::: ::::. ::::::.:..:.::::..:
NP_002 PADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVK
      130       140       150       160       170       180        

             200         210         220       230                 
pF1KB8 IWFQNRRMKWKKEEDKKR--GGGTAVGGG--GVAEPEQDCAVTSGE--------ELLALP
       .:::::::: :.. ....   :  :  :.   . .: .. :.. :         :    :
NP_002 VWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHP
      190       200       210       220       230       240        

     240       250                  260       270       280        
pF1KB8 PPPPPGGAVPPAAPVAAR-EG----------RLPPGLSASPQPSSVAPRRPQEPR     
       :   ::.      :.:.: ::          :   ::  .: : .:   : . :      
NP_002 PEVVPGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPEDVFSGRQDSPFLPDLN
      250       260       270       280       290       300        

NP_002 FFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP
      310       320       330       340       350      




283 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:33:26 2016 done: Fri Nov  4 16:33:28 2016
 Total Scan time:  8.220 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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