FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8935, 284 aa 1>>>pF1KB8935 284 - 284 aa - 284 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8766+/-0.000944; mu= 3.6884+/- 0.057 mean_var=124.1766+/-26.969, 0's: 0 Z-trim(108.4): 16 B-trim: 611 in 1/52 Lambda= 0.115094 statistics sampled from 10199 (10215) to 10199 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.314), width: 16 Scan time: 2.200 The best scores are: opt bits E(32554) CCDS47857.1 TCEA1 gene_id:6917|Hs108|chr8 ( 280) 1739 299.6 1.7e-81 CCDS47858.1 TCEA1 gene_id:6917|Hs108|chr8 ( 301) 1731 298.2 4.6e-81 CCDS13554.1 TCEA2 gene_id:6919|Hs108|chr20 ( 272) 1148 201.4 5.9e-52 CCDS13553.1 TCEA2 gene_id:6919|Hs108|chr20 ( 299) 1148 201.4 6.4e-52 CCDS44086.1 TCEA3 gene_id:6920|Hs108|chr1 ( 348) 843 150.8 1.3e-36 >>CCDS47857.1 TCEA1 gene_id:6917|Hs108|chr8 (280 aa) initn: 1752 init1: 1669 opt: 1739 Z-score: 1576.5 bits: 299.6 E(32554): 1.7e-81 Smith-Waterman score: 1739; 95.4% identity (96.8% similar) in 284 aa overlap (1-284:1-280) 10 20 30 40 50 60 pF1KB8 MEDEVVRFAKKMDKMNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLL ::::::::::::::: . . ::::::::::::::::::::::::::::::::::: CCDS47 MEDEVVRFAKKMDKM----VQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 DGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 DSVQLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISN :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMWKNLTKEAIREHQMAKTGGTQ ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: CCDS47 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQ 180 190 200 210 220 230 250 260 270 280 pF1KB8 TDLFTCGKCKKKNCTYTQVQTRSADEPVTTFVVCNECGNRWKFC :::::::::::::::::::::::::::.:::::::::::::::: CCDS47 TDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 240 250 260 270 280 >>CCDS47858.1 TCEA1 gene_id:6917|Hs108|chr8 (301 aa) initn: 1814 init1: 1731 opt: 1731 Z-score: 1568.8 bits: 298.2 E(32554): 4.6e-81 Smith-Waterman score: 1784; 93.4% identity (94.0% similar) in 301 aa overlap (1-284:1-301) 10 20 30 40 pF1KB8 MEDEVVRFAKKMDKM-----------------NIPMTLELLQSTRIGMSVNAIRKQSTDE ::::::::::::::: :::::::::::::::::::::::::::: CCDS47 MEDEVVRFAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 EVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDET 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 NARDTYVSSFPRAPSTSDSVQLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEI ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS47 NARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 RNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMWKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: CCDS47 RNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 TKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPVTTFVVCNECGNRWKF ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: CCDS47 TKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKF 250 260 270 280 290 300 pF1KB8 C : CCDS47 C >>CCDS13554.1 TCEA2 gene_id:6919|Hs108|chr20 (272 aa) initn: 1135 init1: 918 opt: 1148 Z-score: 1046.3 bits: 201.4 E(32554): 5.9e-52 Smith-Waterman score: 1148; 66.5% identity (83.3% similar) in 269 aa overlap (17-284:10-272) 10 20 30 40 50 60 pF1KB8 MEDEVVRFAKKMDKMNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLL .:.::.::::::.::::::.::::.:::: .::::::::::::: CCDS13 MDLLRELKAMPITLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLL 10 20 30 40 50 70 80 90 100 110 pF1KB8 DGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDT-YVSSFPRAPST :. : : .. . : :: .:. : . .: . : .: ...:: .: : CCDS13 DA-SDAKARERGRGMPLPTS-----SRDASEAPDPSRKRPELPRAPSTPRITTFPPVPVT 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 SDSVQLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRIS :.:. ::::::.:::.: :..::::: :.:..:::: :.... ::::::::::::::: CCDS13 CDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRIS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 NLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMWKNLTKEAIREHQMAKTGGT ::::::::.::.::::: : :. .: ::.::::::::::. : .:::::::::::.:::: CCDS13 NLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGT 170 180 190 200 210 220 240 250 260 270 280 pF1KB8 QTDLFTCGKCKKKNCTYTQVQTRSADEPVTTFVVCNECGNRWKFC ::::::::::.:::::::::::::.:::.:::::::::::::::: CCDS13 QTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC 230 240 250 260 270 >>CCDS13553.1 TCEA2 gene_id:6919|Hs108|chr20 (299 aa) initn: 1135 init1: 918 opt: 1148 Z-score: 1045.6 bits: 201.4 E(32554): 6.4e-52 Smith-Waterman score: 1163; 61.8% identity (79.1% similar) in 301 aa overlap (2-284:5-299) 10 20 30 40 pF1KB8 MEDEVVRFAKKMDKM-----------------NIPMTLELLQSTRIGMSVNAIRKQS :.:..:.:...::: .:.::.::::::.::::::.:::: CCDS13 MMGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPITLHLLQSTRVGMSVNALRKQS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 TDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRK .:::: .::::::::::::::. : : .. . : :: .:. : . .: CCDS13 SDEEVIALAKSLIKSWKKLLDA-SDAKARERGRGMPLPTS-----SRDASEAPDPSRKRP 70 80 90 100 110 110 120 130 140 150 pF1KB8 DETNARDT-YVSSFPRAPSTSDSVQLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAI . : .: ...:: .: : :.:. ::::::.:::.: :..::::: :.:..:::: : CCDS13 ELPRAPSTPRITTFPPVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECI 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB8 YQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEM .... :::::::::::::::::::::::.::.::::: : :. .: ::.::::::::::. CCDS13 FRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEI 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 WKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPVTTFVVCNECGN : .:::::::::::.::::::::::::::.:::::::::::::.:::.::::::::::: CCDS13 RKAMTKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGN 240 250 260 270 280 290 280 pF1KB8 RWKFC ::::: CCDS13 RWKFC >>CCDS44086.1 TCEA3 gene_id:6920|Hs108|chr1 (348 aa) initn: 1045 init1: 809 opt: 843 Z-score: 770.9 bits: 150.8 E(32554): 1.3e-36 Smith-Waterman score: 967; 52.9% identity (74.4% similar) in 312 aa overlap (19-284:38-348) 10 20 30 40 pF1KB8 MEDEVVRFAKKMDKMNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSL :...:::.::::..::..::. .:.::.:: CCDS44 LRIAKKLEKMVARKNTEGALDLLKKLHSCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSL 10 20 30 40 50 60 50 60 70 80 pF1KB8 AKSLIKSWKKLLDGPST---EKDLDE---KKKEPAITSQN-SPEA--------REE---- :: :::.::.:::.:. :: .. :::: .. .. .::: ::. CCDS44 AKVLIKNWKRLLDSPGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKREDPKTR 70 80 90 100 110 120 90 100 110 120 pF1KB8 -----STSSGNVSNRK---DETNARDTYVSSFPRAPS-------------------TSDS : ::.. : .. ...:. . . : :..:: :.:: CCDS44 RDSVDSKSSASSSPKRPSVERSNSSKSKAES-PKTPSSPLTPTFASSMCLLAPCYLTGDS 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB8 VQLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLK :. :: :::.:::.. ::: :.. ....:.::. ::::...:::::.::::::::::: CCDS44 VRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLK 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB8 DAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMWKNLTKEAIREHQMAKTGGTQTD : .::.::.::: : : :.:.:::::::::::.:. . .:.:::::::::::::: :: CCDS44 DPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTD 250 260 270 280 290 300 250 260 270 280 pF1KB8 LFTCGKCKKKNCTYTQVQTRSADEPVTTFVVCNECGNRWKFC :: :.:::::::::.::::::::::.::::.::::::::::: CCDS44 LFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC 310 320 330 340 284 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:35:04 2016 done: Fri Nov 4 16:35:04 2016 Total Scan time: 2.200 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]