FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8938, 290 aa 1>>>pF1KB8938 290 - 290 aa - 290 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8311+/-0.00041; mu= -5.7833+/- 0.026 mean_var=480.3063+/-96.314, 0's: 0 Z-trim(125.4): 101 B-trim: 0 in 0/59 Lambda= 0.058521 statistics sampled from 48814 (48931) to 48814 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.574), width: 16 Scan time: 9.110 The best scores are: opt bits E(85289) NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 2069 188.0 1.9e-47 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 2052 186.5 5e-47 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 788 79.7 6e-15 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 788 79.7 6e-15 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 784 79.4 7.5e-15 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 777 78.8 1.1e-14 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 717 73.3 2.3e-13 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 414 48.2 2e-05 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 411 47.9 2.2e-05 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 406 47.4 2.8e-05 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 396 46.6 5.2e-05 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 396 46.6 5.2e-05 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 396 46.6 5.2e-05 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 396 46.7 6.1e-05 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 388 45.9 8.5e-05 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 379 45.3 0.00016 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 369 44.1 0.0002 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 376 45.3 0.00026 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 376 45.3 0.00026 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 376 45.3 0.00026 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 376 45.3 0.00026 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 376 45.3 0.00026 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 376 45.3 0.00026 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 376 45.3 0.00026 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 369 44.3 0.00026 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 362 43.7 0.00038 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 362 43.8 0.00043 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 339 42.0 0.0018 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 318 40.1 0.0054 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 318 40.1 0.0058 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 316 39.9 0.0061 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 317 40.3 0.008 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 40.3 0.008 NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 310 39.4 0.0088 >>NP_062458 (OMIM: 142985) homeobox protein Hox-D8 isofo (290 aa) initn: 2069 init1: 2069 opt: 2069 Z-score: 973.0 bits: 188.0 E(85289): 1.9e-47 Smith-Waterman score: 2069; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQ 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 VKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN :::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 VKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN 250 260 270 280 290 >>NP_001186675 (OMIM: 142985) homeobox protein Hox-D8 is (289 aa) initn: 1436 init1: 1436 opt: 2052 Z-score: 965.3 bits: 186.5 E(85289): 5e-47 Smith-Waterman score: 2052; 99.7% identity (99.7% similar) in 290 aa overlap (1-290:1-289) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQ ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSQMFPWMRPQA-PGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQ 190 200 210 220 230 250 260 270 280 290 pF1KB8 VKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN 240 250 260 270 280 >>XP_016880053 (OMIM: 142963) PREDICTED: homeobox protei (243 aa) initn: 941 init1: 699 opt: 788 Z-score: 389.4 bits: 79.7 E(85289): 6e-15 Smith-Waterman score: 878; 52.1% identity (68.8% similar) in 288 aa overlap (1-287:1-235) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG ::::::: :.::::. ::.. :.:::: :: ..::: .. .:: :..: XP_016 MSSYFVNSLFSKYKT--------GESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG 10 20 30 40 70 80 90 100 110 120 pF1KB8 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP . ::: . ::..: .. .: :: : XP_016 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP----------- 50 60 70 130 140 150 160 170 pF1KB8 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS :. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .:: XP_016 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS 80 90 100 110 120 180 190 200 210 220 230 pF1KB8 SSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER ::.:.::::::::: :::::::::::.:::::::::::::::::::::::::::.:::: XP_016 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER 130 140 150 160 170 180 240 250 260 270 280 290 pF1KB8 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN ::::::::::::::::::::::: :. : .. : :.. .. : :: XP_016 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK 190 200 210 220 230 240 >>NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [Homo (243 aa) initn: 941 init1: 699 opt: 788 Z-score: 389.4 bits: 79.7 E(85289): 6e-15 Smith-Waterman score: 878; 52.1% identity (68.8% similar) in 288 aa overlap (1-287:1-235) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG ::::::: :.::::. ::.. :.:::: :: ..::: .. .:: :..: NP_076 MSSYFVNSLFSKYKT--------GESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG 10 20 30 40 70 80 90 100 110 120 pF1KB8 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP . ::: . ::..: .. .: :: : NP_076 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP----------- 50 60 70 130 140 150 160 170 pF1KB8 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS :. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .:: NP_076 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS 80 90 100 110 120 180 190 200 210 220 230 pF1KB8 SSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER ::.:.::::::::: :::::::::::.:::::::::::::::::::::::::::.:::: NP_076 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER 130 140 150 160 170 180 240 250 260 270 280 290 pF1KB8 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN ::::::::::::::::::::::: :. : .. : :.. .. : :: NP_076 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK 190 200 210 220 230 240 >>NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [Homo (242 aa) initn: 885 init1: 646 opt: 784 Z-score: 387.6 bits: 79.4 E(85289): 7.5e-15 Smith-Waterman score: 917; 55.2% identity (68.8% similar) in 288 aa overlap (1-286:1-238) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG :::::::::.::::: ::...:.::::.: :: :: . . :.:: : NP_073 MSSYFVNPLFSKYKA--------GESLEPAYYDCRFPQSVGRSHALVYGP----GGSAPG 10 20 30 40 70 80 90 100 110 pF1KB8 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPG-GGSPAAAYQAAPPPPPHPPPPP : :: .: : :..:: : .: ..:: : NP_073 FQHA-----SH-HV----------------QDFFHHGTSGISNSGYQQNP---------- 50 60 70 120 130 140 150 160 170 pF1KB8 PPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSG-NIGEDPDHLNQ :. ..:::. .:::::. : :: .. .:::: .:::::::::.. : .: :::: NP_073 ----CS-LSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ 80 90 100 110 120 130 180 190 200 210 220 230 pF1KB8 SSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTE .:::: :::::::.: :::: :::::::.:::::::::::::::::::::::::::.::: NP_073 NSSPSLMFPWMRPHA-PGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTE 140 150 160 170 180 190 240 250 260 270 280 290 pF1KB8 RQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN ::::::::::::::::::::::.: .:.: : : .: .: ::.. : NP_073 RQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD 200 210 220 230 240 >>XP_005257343 (OMIM: 142963) PREDICTED: homeobox protei (242 aa) initn: 918 init1: 491 opt: 777 Z-score: 384.4 bits: 78.8 E(85289): 1.1e-14 Smith-Waterman score: 867; 52.1% identity (68.8% similar) in 288 aa overlap (1-287:1-234) 10 20 30 40 50 60 pF1KB8 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG ::::::: :.::::. ::.. :.:::: :: ..::: .. .:: :..: XP_005 MSSYFVNSLFSKYKT--------GESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG 10 20 30 40 70 80 90 100 110 120 pF1KB8 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP . ::: . ::..: .. .: :: : XP_005 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP----------- 50 60 70 130 140 150 160 170 pF1KB8 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS :. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .:: XP_005 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS 80 90 100 110 120 180 190 200 210 220 230 pF1KB8 SSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER ::.:.::::::::: :::::::::::.:::::::::::::::::::::::::::.:::: XP_005 PSPTQLFPWMRPQAA-GRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER 130 140 150 160 170 180 240 250 260 270 280 290 pF1KB8 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN ::::::::::::::::::::::: :. : .. : :.. .. : :: XP_005 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK 190 200 210 220 230 240 >>NP_001186676 (OMIM: 142985) homeobox protein Hox-D8 is (106 aa) initn: 717 init1: 717 opt: 717 Z-score: 361.1 bits: 73.3 E(85289): 2.3e-13 Smith-Waterman score: 717; 100.0% identity (100.0% similar) in 106 aa overlap (185-290:1-106) 160 170 180 190 200 210 pF1KB8 ELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEK :::::::::::::::::::::::::::::: NP_001 MFPWMRPQAAPGRRRGRQTYSRFQTLELEK 10 20 30 220 230 240 250 260 270 pF1KB8 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETK 40 50 60 70 80 90 280 290 pF1KB8 KEAQELEEDRAEGLTN :::::::::::::::: NP_001 KEAQELEEDRAEGLTN 100 >>NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [Homo (251 aa) initn: 366 init1: 366 opt: 414 Z-score: 218.6 bits: 48.2 E(85289): 2e-05 Smith-Waterman score: 460; 38.7% identity (58.7% similar) in 230 aa overlap (61-271:17-231) 40 50 60 70 80 90 pF1KB8 YYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPSGTGCGGREGRG :: ... :: : ::. : NP_076 MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQ--RR 10 20 30 40 100 110 120 130 140 pF1KB8 QEYFHP--GGGSPAAA----YQA----APPPPPHPPPPPPPPPCGGIACHGEPAKFYGYD . :.: : : :: : : .::::: ::::::::: :.. .. : NP_076 ESSFQPEAGFGRRAACTVQRYAACRDPGPPPPPPPPPPPPPPP--GLSPRAPAPPPAG-- 50 60 70 80 90 100 150 160 170 180 190 pF1KB8 NLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMR--------PQ : .: . . : : ... . .:.: . . : ..:::: :. NP_076 ALLPEPGQRCEAVSSSPPPPPC--AQNPLHPSPSH-SACKEPV-VYPWMRKVHVSTVNPN 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 AAPGR-RRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMK : :. .:.: .:.: :.::::::: .: ::::.::.:..::: :.:::.:::::::::: NP_076 YAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMK 160 170 180 190 200 210 260 270 280 290 pF1KB8 WKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN :::.. :.: .. ...: NP_076 WKKDH---KLPNTK--IRSGGAAGSAGGPPGRPNGGPRAL 220 230 240 250 >>NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [Homo (230 aa) initn: 428 init1: 339 opt: 411 Z-score: 217.6 bits: 47.9 E(85289): 2.2e-05 Smith-Waterman score: 419; 41.6% identity (63.7% similar) in 190 aa overlap (97-286:39-217) 70 80 90 100 110 120 pF1KB8 QAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGG : :. :.:. .. : . : : . NP_008 ALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPLYQSPFA- 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB8 IACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMF . .: : :: :: : . .:. . :.. . : : . . . ... NP_008 -SGYGLGADAYG--NL---PCASYDQNIPGLCSDLAKGACDKTDEGALH-GAAEANFRIY 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB8 PWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQ :::: ...: :.::::::.:.::::::::: :: ::::.::::..::: :::::.::::: NP_008 PWMR-SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 130 140 150 160 170 250 260 270 280 290 pF1KB8 NRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN :::::::::. ::. :.. . .: . . : :.:. NP_008 NRRMKWKKEH-KDEGPTA-AAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE 180 190 200 210 220 230 >>NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [Homo (217 aa) initn: 427 init1: 345 opt: 406 Z-score: 215.6 bits: 47.4 E(85289): 2.8e-05 Smith-Waterman score: 436; 40.0% identity (61.3% similar) in 230 aa overlap (58-283:22-217) 30 40 50 60 70 80 pF1KB8 NPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG-FPHAPPQAHAHPHPSPPPSGTGCGGR :.: ::. : : .:. : :.: :. NP_004 MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFAS-NPQRPGYGAGSGAS 10 20 30 40 50 90 100 110 120 130 140 pF1KB8 EGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHG---EPAKFYGYDNLQ . ... ..::::. :. :.: .:. : ::..: :.. NP_004 FAASMQGLYPGGGGMAG--QSA----------------AGVYAAGYGLEPSSF----NMH 60 70 80 150 160 170 180 190 200 pF1KB8 RQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQT :. .:. : : ...: :. : . : ...:::: ... :.::::: NP_004 CAPF---EQNLSGVCPGDSAKAAGA-KEQRDSDLAAESNFRIYPWMR-SSGTDRKRGRQT 90 100 110 120 130 140 210 220 230 240 250 260 pF1KB8 YSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPV :.:.::::::::: .: ::::.::::..:.: :::::.::::::::::::::: : : NP_004 YTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKEN-KTAGPG 150 160 170 180 190 200 270 280 290 pF1KB8 SRQEVKDGETKKEAQELEEDRAEGLTN . :. . ::.: ::. NP_004 TT-----GQDRAEAEEEEEE 210 290 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:35:45 2016 done: Fri Nov 4 16:35:46 2016 Total Scan time: 9.110 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]