FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8942, 301 aa 1>>>pF1KB8942 301 - 301 aa - 301 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6748+/-0.000769; mu= 7.4082+/- 0.047 mean_var=191.9625+/-39.968, 0's: 0 Z-trim(115.7): 174 B-trim: 919 in 1/51 Lambda= 0.092569 statistics sampled from 16056 (16247) to 16056 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.499), width: 16 Scan time: 3.050 The best scores are: opt bits E(32554) CCDS4387.1 5 gene_id:1482|Hs108|chr5 ( 324) 718 107.4 1.5e-23 CCDS41558.1 3 gene_id:159296|Hs108|chr10 ( 364) 656 99.2 5.1e-21 CCDS13145.1 2 gene_id:4821|Hs108|chr20 ( 273) 506 79.0 4.4e-15 >>CCDS4387.1 5 gene_id:1482|Hs108|chr5 (324 aa) initn: 652 init1: 424 opt: 718 Z-score: 536.3 bits: 107.4 E(32554): 1.5e-23 Smith-Waterman score: 759; 45.2% identity (64.8% similar) in 330 aa overlap (1-301:1-324) 10 20 30 40 50 pF1KB8 MLLSP-VTSTPFSVKDILRLERE-RSCPAA---SPHPRVRKSPENFQYLRMDAEPRGSEV :. :: .: ::::::::: ::.. :: :: : . .. .: . . . : .. CCDS43 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 HNAGGGGGDRKLDGSEPPGGPCEAVLEMDA----ERMGEPQPGLNAASPLGGGTRVPERG : : : : : . : ... . ...:.: : .: . .. CCDS43 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDP---AKDPRAEKKELCALQ 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQL . ..... .:.:.::.::::::::::::: ::::::::::::::::..:::.:.: CCDS43 KAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKL 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 TSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTP----RRVAVPVLVRDGKPCLGPG-PG ::::::::::::::::::::::..:::.: : : ::.:::::::::::::: . : CCDS43 TSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPY 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 APAFP---SPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAG------ :::. .:: . . : : ::.:: . :: .: :. :.::.: : ..:. CCDS43 APAYGVGLNPY--GYNAYPAYPGYGGAACSPGY-SCTAAYPAGPSPAQPATAAANNNFVN 240 250 260 270 280 290 280 290 300 pF1KB8 FGHGGQNAT-----PQGHLA-ATLQGVRAW :: : ::. ::.. . .::.:.::: CCDS43 FGVGDLNAVQSPGIPQSNSGVSTLHGIRAW 300 310 320 >>CCDS41558.1 3 gene_id:159296|Hs108|chr10 (364 aa) initn: 671 init1: 510 opt: 656 Z-score: 490.9 bits: 99.2 E(32554): 5.1e-21 Smith-Waterman score: 722; 46.7% identity (68.3% similar) in 306 aa overlap (1-289:2-298) 10 20 30 40 pF1KB8 MLLSPVTSTPFSVKDILRLERERS------CPAASPH-----PRVRKSPENFQYL---R :: :::::::::::::: ::.... : : : . . :. :. . CCDS41 MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 MDAEPRGSEVHNAGG-GGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGG : : .: .. .. ...: . :.. : : ..::. . . : . ... . CCDS41 EDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREH . .... ..:: . .::.:: :.:::::::::::::. :::::::::::::::::: CCDS41 SCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREH 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 LASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGH--PLTPRRVAVPVLVRDGKPCLG :::.:.::::::::::::::::::::::::::::..: : ::::::::::::::::. CCDS41 LASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVT 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 PGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGG : .: :. .:::...: :: :.. : . :::. :.: .. : . :.:... . CCDS41 P--SAQAYGAPYSVGASAYS----YNSFP-AYGYGNSAAAAAAAAA--AAAAAAAYSSSY 250 260 270 280 290 290 300 pF1KB8 QNATPQGHLAATLQGVRAW : : : CCDS41 GCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGA 300 310 320 330 340 350 >>CCDS13145.1 2 gene_id:4821|Hs108|chr20 (273 aa) initn: 484 init1: 349 opt: 506 Z-score: 384.2 bits: 79.0 E(32554): 4.4e-15 Smith-Waterman score: 509; 40.4% identity (61.0% similar) in 282 aa overlap (7-276:6-268) 10 20 30 40 50 60 pF1KB8 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGG :.: ::::::: : . . . : ..::. : .: : . .: CCDS13 MSLTNTKTGFSVKDILDLP-----DTNDEEGSVAEGPEE--------ENEGPEPAKRAG 10 20 30 40 70 80 90 100 110 pF1KB8 GGGDRKLDG--SEPPGGPCEAVLEMDAERMGEPQPGLN--------AASPLGGGTRVPER :. ::. : : .: . : ::. .: : .... :: CCDS13 PLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 GVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQ .. .: :. . . : ..:: :::::.::. :::::.::::::::::::::: .. CCDS13 SADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 LTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAF :: :::::::::.::: :: : .:..:.. : .:::::::::::::::: . : CCDS13 LTPTQVKIWFQNHRYKMKRARAEKGMEVTPLP-SPRRVAVPVLVRDGKPCHALKAQDLA- 170 180 190 200 210 220 240 250 260 270 280 pF1KB8 PSPYSAAVSPYSCYGGYS--GAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQ . ..:.. :.: :.. : :.: :.. :..:. :. : ::..: CCDS13 AATFQAGI-PFSAYSAQSLQHMQYNAQYSS--ASTPQYPTAH-PLVQAQQWTW 230 240 250 260 270 290 300 pF1KB8 GHLAATLQGVRAW 301 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:36:22 2016 done: Fri Nov 4 16:36:23 2016 Total Scan time: 3.050 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]