FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8945, 304 aa 1>>>pF1KB8945 304 - 304 aa - 304 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5752+/-0.000334; mu= 8.1677+/- 0.021 mean_var=242.0812+/-49.791, 0's: 0 Z-trim(123.3): 223 B-trim: 0 in 0/55 Lambda= 0.082432 statistics sampled from 42477 (42771) to 42477 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.501), width: 16 Scan time: 6.690 The best scores are: opt bits E(85289) NP_573574 (OMIM: 616253) GS homeobox 2 [Homo sapie ( 304) 2111 263.3 4.5e-70 NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264) 516 73.5 5.2e-13 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 324 50.7 3.9e-06 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 324 50.7 3.9e-06 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 313 49.3 9.3e-06 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 310 49.1 1.4e-05 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 303 48.4 2.7e-05 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 301 48.2 3.5e-05 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 301 48.2 3.5e-05 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 293 46.9 4.8e-05 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 291 46.8 6.1e-05 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 290 46.7 7.2e-05 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 287 46.3 8.3e-05 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 286 46.2 9.6e-05 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 286 46.3 0.00011 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 286 46.3 0.00011 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 286 46.4 0.00012 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 286 46.4 0.00012 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 286 46.4 0.00012 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 286 46.4 0.00012 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 286 46.4 0.00012 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 286 46.4 0.00012 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 286 46.4 0.00012 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 286 46.5 0.00013 XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 286 46.6 0.00014 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 279 45.3 0.00015 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 280 45.5 0.00016 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 277 45.1 0.00019 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 279 45.5 0.00019 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 277 45.3 0.00026 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 277 45.3 0.00026 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 277 45.3 0.00026 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 277 45.3 0.00026 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 277 45.3 0.00026 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 277 45.3 0.00026 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 277 45.3 0.00026 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 273 44.7 0.00028 >>NP_573574 (OMIM: 616253) GS homeobox 2 [Homo sapiens] (304 aa) initn: 2111 init1: 2111 opt: 2111 Z-score: 1379.1 bits: 263.3 E(85289): 4.5e-70 Smith-Waterman score: 2111; 100.0% identity (100.0% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB8 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 CPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 RVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 ADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 LSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKE 250 260 270 280 290 300 pF1KB8 ISPL :::: NP_573 ISPL >>NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapiens] (264 aa) initn: 649 init1: 415 opt: 516 Z-score: 354.6 bits: 73.5 E(85289): 5.2e-13 Smith-Waterman score: 725; 45.0% identity (64.8% similar) in 318 aa overlap (1-302:1-261) 10 20 30 40 50 pF1KB8 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPG-CPSRKSGAFC : ::: ::::....... :: : : : : ..::: .. .:: : .::.: .: NP_663 MPRSFLVDSLVLREAGEKKA--PEGSPPPLF--PYAVPPPHALHGLSPGACHARKAGLLC 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 VCPLCVT-SHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQF ::::::: :.::. : ::::::..: : .:. NP_663 VCPLCVTASQLHGPPGP------------------------PALPLLKASFP--PFGSQY 60 70 80 90 120 130 140 150 160 170 pF1KB8 CPRVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTY : : : .. :. .:: .: . ::::::::: . :.: NP_663 C----------HAPLGRQ--HSAVSPG----VAHGPAAAAAAAALYQ----------TSY 100 110 120 180 190 200 210 220 230 pF1KB8 NVADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATY . :::.:::... .: ..:.:..:::::::::::::::::::.:::::::::::::::: NP_663 PLPDPRQFHCISVDSS-SNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATY 130 140 150 160 170 180 240 250 260 270 280 pF1KB8 LNLSEKQVKIWFQNRRVKHKKEGKGTQR------------NSHAGCKCVG-SQVHYARSE :::::::::::::::::::::::::... .. ::::.. :... .... NP_663 LNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDD 190 200 210 220 230 240 290 300 pF1KB8 DEDSLSPASAN-DDKEISPL :: .::.:.. ::.... NP_663 DELPMSPSSSGKDDRDLTVTP 250 260 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 363 init1: 248 opt: 324 Z-score: 231.2 bits: 50.7 E(85289): 3.9e-06 Smith-Waterman score: 324; 42.1% identity (63.6% similar) in 140 aa overlap (129-262:81-216) 100 110 120 130 140 150 pF1KB8 AGALPLLKSQFSSAPGDAQFCPRVNHAHHHHHPPQHHHHHHQPQQ----PGSAAAAAAAA : : : ::: . .: :. ..:.:. NP_705 ELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASP 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 AAAAAAAALGHPQHHAPVCTATTYNVADP--RRFHCLTMGGSDASQVPNGKRMRTAFTST . : : . :.: : .:. .. : ...: :.. . . : :: :::.: NP_705 SPAPPACSQPAPDH--PSSAASKQPIVYPWMKKIHVSTVNPNYNGGEP--KRSRTAYTRQ 120 130 140 150 160 220 230 240 250 260 270 pF1KB8 QLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGC :.::::.:: : ::.: :::::: : :::.:.::::::::.: ::. . NP_705 QVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAP 170 180 190 200 210 220 280 290 300 pF1KB8 KCVGSQVHYARSEDEDSLSPASANDDKEISPL NP_705 PAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 230 240 250 260 >>NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 363 init1: 248 opt: 324 Z-score: 231.2 bits: 50.7 E(85289): 3.9e-06 Smith-Waterman score: 324; 42.1% identity (63.6% similar) in 140 aa overlap (129-262:81-216) 100 110 120 130 140 150 pF1KB8 AGALPLLKSQFSSAPGDAQFCPRVNHAHHHHHPPQHHHHHHQPQQ----PGSAAAAAAAA : : : ::: . .: :. ..:.:. NP_055 ELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASP 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 AAAAAAAALGHPQHHAPVCTATTYNVADP--RRFHCLTMGGSDASQVPNGKRMRTAFTST . : : . :.: : .:. .. : ...: :.. . . : :: :::.: NP_055 SPAPPACSQPAPDH--PSSAASKQPIVYPWMKKIHVSTVNPNYNGGEP--KRSRTAYTRQ 120 130 140 150 160 220 230 240 250 260 270 pF1KB8 QLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGC :.::::.:: : ::.: :::::: : :::.:.::::::::.: ::. . NP_055 QVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAP 170 180 190 200 210 220 280 290 300 pF1KB8 KCVGSQVHYARSEDEDSLSPASANDDKEISPL NP_055 PAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 230 240 250 260 >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 299 init1: 250 opt: 313 Z-score: 224.3 bits: 49.3 E(85289): 9.3e-06 Smith-Waterman score: 313; 35.5% identity (55.6% similar) in 214 aa overlap (77-277:26-234) 50 60 70 80 90 100 pF1KB8 GPGCPSRKSGAFCVCPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGAL---P :. : :: :.:..:. .: : NP_055 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRP 10 20 30 40 50 110 120 130 140 150 160 pF1KB8 LLKSQ-FS-SAPGDAQFCPRVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAA . : :. :.:: .. : .:... : :. : .: : : : .: : NP_055 DFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHY---AAPGEPCPAPPAPPPAPLPGARA 60 70 80 90 100 110 170 180 190 200 210 pF1KB8 ALGHPQHHAPVCTATTY-NVADP--RRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELE .. : :: :. : .. : ... . .. : :: :::.: :.:::: NP_055 YSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEP--KRSRTAYTRQQVLELE 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB8 REFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK-----GTQRNSHAGCK .:: : ::.: :::::: : :::.:.::::::::.: ::. : : . .: .. . NP_055 KEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSS 180 190 200 210 220 230 280 290 300 pF1KB8 CVGSQVHYARSEDEDSLSPASANDDKEISPL : .: NP_055 CSSSVAPSQHLQPMAKDHHTDLTTL 240 250 >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 318 init1: 251 opt: 310 Z-score: 221.3 bits: 49.1 E(85289): 1.4e-05 Smith-Waterman score: 310; 32.7% identity (52.5% similar) in 263 aa overlap (25-276:36-292) 10 20 30 40 50 pF1KB8 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRK : :: . : :: . .. : : NP_002 FLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQP-PAPPTQHLPLQQPQLPHAG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 SGAFCVCPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPG .: . . . ..: . ::. : : : : :: : : . :. NP_002 GGREPTASYYAPRTAREPAYPAAALYPAHGAADT-AYPYGYRG--GASPGRPPQPEQPPA 70 80 90 100 110 120 120 130 140 150 160 pF1KB8 DAQFCPRVNHAHH---HHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHP---QH .:. . :: : . :: . . : : :: :. .. :...: . : NP_002 QAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLAD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 HAPVCTATTYNVADP--RRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMY ..:. :. : ...: ... : . : :: :::.: :.::::.:: : : NP_002 KSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEP--KRSRTAYTRQQVLELEKEFHFNRY 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 LSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK--GTQ-RNSHAGCKCVGSQVHYAR :.: :::::: : :::.::::::::::.: ::. : .:. :.:... .: NP_002 LTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQT 240 250 260 270 280 290 290 300 pF1KB8 SEDEDSLSPASANDDKEISPL NP_002 QSPHLHPHPHPSTSTPVPSSI 300 310 320 >>NP_006726 (OMIM: 604685,612290) homeobox protein Hox-A (376 aa) initn: 451 init1: 260 opt: 303 Z-score: 216.0 bits: 48.4 E(85289): 2.7e-05 Smith-Waterman score: 331; 39.6% identity (65.9% similar) in 164 aa overlap (130-290:91-232) 100 110 120 130 140 150 pF1KB8 GALPLLKSQFSSAPGDAQFCPRVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAA .::.. . .. .. .: ::::::. NP_006 PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPW--MKEKKAAKKTALLPAAAAAAT 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 AAALGHPQHHAPVCTA--TTYNVADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLEL ::: : :.: . . ..:: . ::: .:.:::.:.:::::: NP_006 AAATG------PACLSHKESLEIADG------SGGGS--------RRLRTAYTNTQLLEL 120 130 140 150 220 230 240 250 260 270 pF1KB8 EREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQ-RNSHAGCKCVG :.:: : :: : ::.:::. :.:.:.:::.::::::.:::.. . . .::.. :: . NP_006 EKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLE 160 170 180 190 200 210 280 290 300 pF1KB8 SQVHYARSEDEDSLSPASANDDKEISPL .. . ..:.: .: NP_006 DSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLT 220 230 240 250 260 270 >>XP_006712540 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 319 init1: 266 opt: 301 Z-score: 214.0 bits: 48.2 E(85289): 3.5e-05 Smith-Waterman score: 309; 32.6% identity (55.2% similar) in 230 aa overlap (38-262:51-254) 10 20 30 40 50 60 pF1KB8 DSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCVCPLCVTS ::: . : :. . :: . . XP_006 AYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPA 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB8 HLHSSRGSVGAGSGG-AGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCPRVNHAH : .:. :: :.: . .::.: . : :.:. .. : : . XP_006 H----KGAELNGSCMRPGTGNSQGGGGG-----SQPPGLNSE-QQPPQPPPPPPTL---- 90 100 110 120 130 140 150 160 170 180 pF1KB8 HHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHA-PVCTATTYNVADPRR ::. .: .::... : .. :... . ... : . : . .. XP_006 ----PPS------SPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQN--SKQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 FHCLTMGGSDASQVPNG---KRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLS : : : : .. : : ::.:::.::.::.:::.:: : :: : ::.:.:. :::. XP_006 NSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 EKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKEIS :.:.::::::::.:.::. : XP_006 ERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAY 240 250 260 270 280 290 >>XP_005246567 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 319 init1: 266 opt: 301 Z-score: 214.0 bits: 48.2 E(85289): 3.5e-05 Smith-Waterman score: 309; 32.6% identity (55.2% similar) in 230 aa overlap (38-262:51-254) 10 20 30 40 50 60 pF1KB8 DSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCVCPLCVTS ::: . : :. . :: . . XP_005 AYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPA 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB8 HLHSSRGSVGAGSGG-AGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCPRVNHAH : .:. :: :.: . .::.: . : :.:. .. : : . XP_005 H----KGAELNGSCMRPGTGNSQGGGGG-----SQPPGLNSE-QQPPQPPPPPPTL---- 90 100 110 120 130 140 150 160 170 180 pF1KB8 HHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHA-PVCTATTYNVADPRR ::. .: .::... : .. :... . ... : . : . .. XP_005 ----PPS------SPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQN--SKQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 FHCLTMGGSDASQVPNG---KRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLS : : : : .. : : ::.:::.::.::.:::.:: : :: : ::.:.:. :::. XP_005 NSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 EKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKEIS :.:.::::::::.:.::. : XP_005 ERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAY 240 250 260 270 280 290 >>XP_005246566 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 319 init1: 266 opt: 301 Z-score: 214.0 bits: 48.2 E(85289): 3.5e-05 Smith-Waterman score: 309; 32.6% identity (55.2% similar) in 230 aa overlap (38-262:51-254) 10 20 30 40 50 60 pF1KB8 DSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCVCPLCVTS ::: . : :. . :: . . XP_005 AYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPA 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB8 HLHSSRGSVGAGSGG-AGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCPRVNHAH : .:. :: :.: . .::.: . : :.:. .. : : . XP_005 H----KGAELNGSCMRPGTGNSQGGGGG-----SQPPGLNSE-QQPPQPPPPPPTL---- 90 100 110 120 130 140 150 160 170 180 pF1KB8 HHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHA-PVCTATTYNVADPRR ::. .: .::... : .. :... . ... : . : . .. XP_005 ----PPS------SPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQN--SKQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 FHCLTMGGSDASQVPNG---KRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLS : : : : .. : : ::.:::.::.::.:::.:: : :: : ::.:.:. :::. XP_005 NSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 EKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKEIS :.:.::::::::.:.::. : XP_005 ERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAY 240 250 260 270 280 290 304 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:36:53 2016 done: Fri Nov 4 16:36:54 2016 Total Scan time: 6.690 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]